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Issue Archive

Volume 130, Issue 21
November 23 2017
Issue Cover

Table of Contents

INSIDE BLOOD COMMENTARIES

INSIDE BLOOD COMMENTARY
Chronic GVHD: progress in salvage treatment?
Clinical Trials & Observations
Hildegard T. Greinix
View Articletitled, Chronic GVHD: progress in salvage treatment?
INSIDE BLOOD COMMENTARY
CAR emissions: cytokines tell the story
Shannon L. Maude
View Articletitled, CAR emissions: cytokines tell the story
INSIDE BLOOD COMMENTARY
Road trip to remission with CARs
Samantha M. Jaglowski
View Articletitled, Road trip to remission with CARs
INSIDE BLOOD COMMENTARY
Low VWF: an established mild bleeding disorder?
Frank W. G. Leebeek,Johan Boender
View Articletitled, Low VWF: an established mild bleeding disorder?

PLENARY PAPER

CLINICAL TRIALS AND OBSERVATIONS
Ibrutinib for chronic graft-versus-host disease after failure of prior therapy
Clinical Trials & Observations
David Miklos,Corey S. Cutler,Mukta Arora,Edmund K. Waller,Madan Jagasia,Iskra Pusic,Mary E. Flowers,Aaron C. Logan,Ryotaro Nakamura,Bruce R. Blazar,Yunfeng Li,Stephen Chang,Indu Lal,Jason Dubovsky,Danelle F. James,Lori Styles,Samantha Jaglowski
View Articletitled, Ibrutinib for chronic graft-versus-host disease after failure of prior therapy
Supplemental data

BLOOD SPOTLIGHT

Novel approaches to hemophilia therapy: successes and challenges
Clinical Trials & Observations
Valder R. Arruda,Bhavya S. Doshi,Benjamin J. Samelson-Jones
View Articletitled, Novel approaches to hemophilia therapy: successes and challenges

REVIEW ARTICLE

Inherited bone marrow failure syndromes: considerations pre- and posttransplant
Clinical Trials & Observations
Blanche P. Alter
View Articletitled, Inherited bone marrow failure syndromes: considerations pre- and posttransplant
Signaling pathways and immune evasion mechanisms in classical Hodgkin lymphoma
Clinical Trials & Observations
W. Robert Liu,Margaret A. Shipp
View Articletitled, Signaling pathways and immune evasion mechanisms in classical Hodgkin lymphoma
Thrombocytopenia in pregnancy
Clinical Trials & Observations
Douglas B. Cines,Lisa D. Levine
View Articletitled, Thrombocytopenia in pregnancy

EVIDENCE-BASED FOCUSED REVIEW

FCR achieves long-term durable remissions in patients with IGHV-mutated CLL
Clinical Trials & Observations
Chatree Chai-Adisaksopha,Jennifer R. Brown
View Articletitled, FCR achieves long-term durable remissions in patients with <em>IGHV</em>-mutated CLL
Supplemental data

HEMATOPOIESIS AND STEM CELLS

TGF-β–induced intracellular PAI-1 is responsible for retaining hematopoietic stem cells in the niche
Takashi Yahata,Abd Aziz Ibrahim,Yukari Muguruma,Mesut Eren,Alexander M. Shaffer,Nobuo Watanabe,Satoko Kaneko,Tetsuo Nakabayashi,Takashi Dan,Noriaki Hirayama,Douglas E. Vaughan,Toshio Miyata,Kiyoshi Ando
View Articletitled, TGF-β–induced intracellular PAI-1 is responsible for retaining hematopoietic stem cells in the niche
Supplemental data

IMMUNOBIOLOGY AND IMMUNOTHERAPY

Kinetics and biomarkers of severe cytokine release syndrome after CD19 chimeric antigen receptor–modified T-cell therapy
Clinical Trials & Observations
Kevin A. Hay,Laïla-Aïcha Hanafi,Daniel Li,Juliane Gust,W. Conrad Liles,Mark M. Wurfel,José A. López,Junmei Chen,Dominic Chung,Susanna Harju-Baker,Sindhu Cherian,Xueyan Chen,Stanley R. Riddell,David G. Maloney,Cameron J. Turtle
View Articletitled, Kinetics and biomarkers of severe cytokine release syndrome after CD19 chimeric antigen receptor–modified T-cell therapy
Supplemental data
Effective “activated PI3Kδ syndrome”–targeted therapy with the PI3Kδ inhibitor leniolisib
Clinical Trials & Observations
V. Koneti Rao,Sharon Webster,Virgil A. S. H. Dalm,Anna Šedivá,P. Martin van Hagen,Steven Holland,Sergio D. Rosenzweig,Andreas D. Christ,Birgitte Sloth,Maciej Cabanski,Aniket D. Joshi,Stefan de Buck,Julie Doucet,Danilo Guerini,Christoph Kalis,Ilona Pylvaenaeinen,Nicolas Soldermann,Anuj Kashyap,Gulbu Uzel,Michael J. Lenardo,Dhavalkumar D. Patel,Carrie L. Lucas,Christoph Burkhart
View Articletitled, Effective “activated PI3Kδ syndrome”–targeted therapy with the PI3Kδ inhibitor leniolisib
Supplemental data

LYMPHOID NEOPLASIA

Cellular kinetics of CTL019 in relapsed/refractory B-cell acute lymphoblastic leukemia and chronic lymphocytic leukemia
Karen Thudium Mueller,Shannon L. Maude,David L. Porter,Noelle Frey,Patricia Wood,Xia Han,Edward Waldron,Abhijit Chakraborty,Rakesh Awasthi,Bruce L. Levine,J. Joseph Melenhorst,Stephan A. Grupp,Carl H. June,Simon F. Lacey
View Articletitled, Cellular kinetics of CTL019 in relapsed/refractory B-cell acute lymphoblastic leukemia and chronic lymphocytic leukemia
Supplemental data
Enhancer profiling identifies critical cancer genes and characterizes cell identity in adult T-cell leukemia
Regina Wan Ju Wong,Phuong Cao Thi Ngoc,Wei Zhong Leong,Alice Wei Yee Yam,Tinghu Zhang,Kaori Asamitsu,Shinsuke Iida,Takashi Okamoto,Ryuzo Ueda,Nathanael S. Gray,Takashi Ishida,Takaomi Sanda
View Articletitled, Enhancer profiling identifies critical cancer genes and characterizes cell identity in adult T-cell leukemia
Supplemental data

RED CELLS, IRON, AND ERYTHROPOIESIS

Deletion of BMP6 worsens the phenotype of HJV-deficient mice and attenuates hepcidin levels reached after LPS challenge
Brief Report
Chloé Latour,Céline Besson-Fournier,Ophélie Gourbeyre,Delphine Meynard,Marie-Paule Roth,Hélène Coppin
View Articletitled, Deletion of BMP6 worsens the phenotype of HJV-deficient mice and attenuates hepcidin levels reached after LPS challenge
Supplemental data

THROMBOSIS AND HEMOSTASIS

Novel insights into the clinical phenotype and pathophysiology underlying low VWF levels
Clinical Trials & Observations
Michelle Lavin,Sonia Aguila,Sonja Schneppenheim,Niall Dalton,Kenneth L. Jones,Jamie M. O’Sullivan,Niamh M. O’Connell,Kevin Ryan,Barry White,Mary Byrne,Marie Rafferty,Mairead M. Doyle,Margaret Nolan,Roger J. S. Preston,Ulrich Budde,Paula James,Jorge Di Paola,James S. O’Donnell
View Articletitled, Novel insights into the clinical phenotype and pathophysiology underlying low VWF levels
Supplemental data

LETTER TO BLOOD

Adverse effect of hydroxyurea on spermatogenesis in patients with sickle cell anemia after 6 months of treatment
Isabelle Berthaut,Dora Bachir,Salma Kotti,Céline Chalas,Katia Stankovic,Florence Eustache,Célia Ravel,Anoosha Habibi,Sylvie Brailly-Tabard,Laurence Lévy-Dutel,Alexandre Bleibtreu,Tabassome Simon,Frédéric Galactéros,François Lionnet,Jacqueline Mandelbaum
View Articletitled, Adverse effect of hydroxyurea on spermatogenesis in patients with sickle cell anemia after 6 months of treatment

BLOOD WORK

Carcinocythemia (carcinoma cell leukemia)
Andrew J. Johnsrud,Sergio Pina-Oviedo
View Articletitled, Carcinocythemia (carcinoma cell leukemia)
“Soccer ball” cells to “donut” cells: an unusual case of Richter syndrome
Beenu Thakral,Sergej Konoplev
View Articletitled, “Soccer ball” cells to “donut” cells: an unusual case of Richter syndrome
All Issues

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