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Journal Articles

Generation and Characterisation of KY1066, a Fully Human Antibody Targeting the Enzymatic Activity of Matriptase-2 for the Treatment of Iron Overload in Beta Thalassemia

Matthew Wake, PhD, Jonathan Papworth, BSc, Luke Bayliss, BSc, Benjamin Grimshaw, PhD, Natalie Rynkiewicz, PhD, Jemima Paterson, BSc, Alicia Poindron, MSc, Erin Spearing, Emily Carter, Robyne Hudson, BSc, Verena Petzer, MD, Amelie Largounez, BSc, Audrey Belot, BSc, Anais Palin, BSc, Igor Theurl, MD PhD, Volker Germaschewski, Delphine Meynard, PhD

Blood (2019) 134 (Supplement_1): 3532.

https://doi.org/10.1182/blood-2019-124075

Published: 2019

Journal Articles

Deletion of BMP6 Worsens the Phenotype of Hemojuvelin-Deficient Mice and Attenuates Hepcidin Levels Reached after LPS Stimulation

Chloé Latour, Céline Besson-Fournier, Ophélie Gourbeyre, Delphine Meynard, PhD, Aguilar-Martinez Patricia, MD PhD, Marie-Paule Roth, MD, Helene Coppin, PhD

Blood (2017) 130 (Supplement 1): 226.

https://doi.org/10.1182/blood.V130.Suppl_1.226.226

Published: 2017

Journal Articles

Deletion of BMP6 worsens the phenotype of HJV-deficient mice and attenuates hepcidin levels reached after LPS challenge

Chloé Latour, Céline Besson-Fournier, Ophélie Gourbeyre, Delphine Meynard, Marie-Paule Roth, Hélène Coppin

Blood (2017) 130 (21): 2339–2343.

https://doi.org/10.1182/blood-2017-07-795658

Published: 2017

Includes: Supplemental data

Journal Articles

Hepcidin upregulation by inflammation is independent of Smad1/5/8 signaling by activin B

Céline Besson-Fournier, Aurélie Gineste, Chloé Latour, Ophélie Gourbeyre, Delphine Meynard, Patricia Martin, Eric Oswald, Hélène Coppin, Marie-Paule Roth

Blood (2017) 129 (4): 533–536.

https://doi.org/10.1182/blood-2016-10-748541

Published: 2017

Includes: Supplemental data

Journal Articles

Hepcidin Upregulation By Inflammation Is Not Causally Related to Liver Activation of Smad1/5/8 Signaling By Activin B

Celine Besson-Fournier, Aurelie Gineste, Chloe Latour, Ophelie Gourbeyre, Delphine Meynard, PhD, Patricia Aguilar-Martinez, MD PhD, Eric Oswald, DVM, PhD, Patricia Martin, PhD, Helene Coppin, PhD, Marie-Paule Roth, MD

Blood (2016) 128 (22): 262.

https://doi.org/10.1182/blood.V128.22.262.262

Published: 2016

Journal Articles

Limiting hepatic Bmp-Smad signaling by matriptase-2 is required for erythropoietin-mediated hepcidin suppression in mice

Antonella Nai, Aude Rubio, Alessandro Campanella, Ophélie Gourbeyre, Irene Artuso, Jessica Bordini, Aurélie Gineste, Chloé Latour, Céline Besson-Fournier, Herbert Y. Lin, Hélène Coppin, Marie-Paule Roth, Clara Camaschella, Laura Silvestri, Delphine Meynard

Blood (2016) 127 (19): 2327–2336.

https://doi.org/10.1182/blood-2015-11-681494

Published: 2016

Includes: Supplemental data

Journal Articles

The liver: conductor of systemic iron balance

Delphine Meynard, Jodie L. Babitt, Herbert Y. Lin

Blood (2014) 123 (2): 168–176.

https://doi.org/10.1182/blood-2013-06-427757

Published: 2014

Journal Articles

Regulation of TMPRSS6 by BMP6 and iron in human cells and mice

Delphine Meynard, Valentina Vaja, Chia Chi Sun, Elena Corradini, Shanzhuo Chen, Carlos López-Otín, Lovorka Grgurevic, Charles C. Hong, Marit Stirnberg, Michael Gütschow, Slobodan Vukicevic, Jodie L. Babitt, Herbert Y. Lin

Blood (2011) 118 (3): 747–756.

https://doi.org/10.1182/blood-2011-04-348698

Published: 2011

Includes: Supplemental data

Journal Articles

BMP/Smad signaling is not enhanced in Hfe -deficient mice despite increased Bmp6 expression

Léon Kautz, Delphine Meynard, Céline Besson-Fournier, Valérie Darnaud, Talal Al Saati, Hélène Coppin, Marie-Paule Roth

Blood (2009) 114 (12): 2515–2520.

https://doi.org/10.1182/blood-2009-02-206771

Published: 2009

Includes: Supplemental data

Journal Articles

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1 , and Atoh8 in the mouse liver

Léon Kautz, Delphine Meynard, Annabelle Monnier, Valérie Darnaud, Régis Bouvet, Rui-Hong Wang, Chiuxia Deng, Sophie Vaulont, Jean Mosser, Hélène Coppin, Marie-Paule Roth

Blood (2008) 112 (4): 1503–1509.

https://doi.org/10.1182/blood-2008-03-143354

Published: 2008

Includes: Supplemental data

NARROW

Generation and Characterisation of KY1066, a Fully Human Antibody Targeting the Enzymatic Activity of Matriptase-2 for the Treatment of Iron Overload in Beta Thalassemia

Deletion of BMP6 Worsens the Phenotype of Hemojuvelin-Deficient Mice and Attenuates Hepcidin Levels Reached after LPS Stimulation

Deletion of BMP6 worsens the phenotype of HJV-deficient mice and attenuates hepcidin levels reached after LPS challenge

Hepcidin upregulation by inflammation is independent of Smad1/5/8 signaling by activin B

Hepcidin Upregulation By Inflammation Is Not Causally Related to Liver Activation of Smad1/5/8 Signaling By Activin B

Limiting hepatic Bmp-Smad signaling by matriptase-2 is required for erythropoietin-mediated hepcidin suppression in mice

The liver: conductor of systemic iron balance

Regulation of TMPRSS6 by BMP6 and iron in human cells and mice

BMP/Smad signaling is not enhanced in Hfe -deficient mice despite increased Bmp6 expression

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1 , and Atoh8 in the mouse liver

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American Society of Hematology

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ASH Publications

American Society of Hematology

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