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Monitoring of childhood ALL using BCR-ABL1 genomic breakpoints identifies a subgroup with CML-like biology
Lower levels of vitamin A are associated with increased gastrointestinal graft-versus-host disease in children
Long-term follow-up of patients with CLL treated with the selective Bruton’s tyrosine kinase inhibitor ONO/GS-4059
Impact of doxorubicin dose capping on the outcome of DLBCL patients with elevated body surface area
Issue Archive
Table of Contents
INSIDE BLOOD COMMENTARIES
PERSPECTIVE
HOW I TREAT
HEMATOPOIESIS AND STEM CELLS
Hsp90 inhibition destabilizes Ezh2 protein in alloreactive T cells and reduces graft-versus-host disease in mice
Qingrong Huang,Shan He,Yuanyuan Tian,Yuting Gu,Pan Chen,Changhong Li,Jiefang Huang,Yongnian Liu,Hongshuang Yu,Min Jin,Shaoyan Hu,Qing Tong,Anqi Ma,Jian Jin,Elizabeth Hexner,Henry Fung,Ran Reshef,Yi Zhang,Yanyun Zhang
IMMUNOBIOLOGY
LYMPHOID NEOPLASIA
Genetic profiling of MYC and BCL2 in diffuse large B-cell lymphoma determines cell-of-origin–specific clinical impact
Daisuke Ennishi,Anja Mottok,Susana Ben-Neriah,Hennady P. Shulha,Pedro Farinha,Fong Chun Chan,Barbara Meissner,Merrill Boyle,Christoffer Hother,Robert Kridel,Daniel Lai,Saeed Saberi,Ali Bashashati,Sohrab P. Shah,Ryan D. Morin,Marco A. Marra,Kerry J. Savage,Laurie H. Sehn,Christian Steidl,Joseph M. Connors,Randy D. Gascoyne,David W. Scott
Monitoring of childhood ALL using BCR-ABL1 genomic breakpoints identifies a subgroup with CML-like biology
Clinical Trials & Observations
Lenka Hovorkova,Marketa Zaliova,Nicola C. Venn,Kirsten Bleckmann,Marie Trkova,Eliska Potuckova,Martina Vaskova,Jana Linhartova,Katerina Machova Polakova,Eva Fronkova,Walter Muskovic,Jodie E. Giles,Peter J. Shaw,Gunnar Cario,Rosemary Sutton,Jan Stary,Jan Trka,Jan Zuna
MYELOID NEOPLASIA
Caspase-3 controls AML1-ETO–driven leukemogenesis via autophagy modulation in a ULK1-dependent manner
Na Man,Yurong Tan,Xiao-Jian Sun,Fan Liu,Guoyan Cheng,Sarah M. Greenblatt,Camilo Martinez,Daniel L. Karl,Koji Ando,Ming Sun,Dan Hou,Bingyi Chen,Mingjiang Xu,Feng-Chun Yang,Zhu Chen,Saijuan Chen,Stephen D. Nimer,Lan Wang
THROMBOSIS AND HEMOSTASIS
TRANSPLANTATION
Lower levels of vitamin A are associated with increased gastrointestinal graft-versus-host disease in children
Clinical Trials & Observations
Dana T. Lounder,Pooja Khandelwal,Christopher E. Dandoy,Sonata Jodele,Michael S. Grimley,Gregory Wallace,Adam Lane,Cynthia Taggart,Ashley C. Teusink-Cross,Kelly E. Lake,Stella M. Davies
LETTERS TO BLOOD
Long-term follow-up of patients with CLL treated with the selective Bruton’s tyrosine kinase inhibitor ONO/GS-4059
Clinical Trials & Observations
Harriet S. Walter,Sandrine Jayne,Simon A. Rule,Guillaume Cartron,Franck Morschhauser,Salvador Macip,Lionel Karlin,Ceri Jones,Charles Herbaux,Philippe Quittet,Nimish Shah,Claire V. Hutchinson,Christopher Fegan,Yingsi Yang,Siddhartha Mitra,Gilles Salles,Martin J. S. Dyer
Impact of doxorubicin dose capping on the outcome of DLBCL patients with elevated body surface area
Clinical Trials & Observations
Caroline Gay,Richard Delarue,Noel Milpied,Lucie Oberic,Bertrand Coiffier,Sami Boussetta,Corinne Haioun,Hervé Tilly,Gilles Salles,Thierry Lamy,Marie-Antoinette Lester,Roch Houot
BLOOD WORK
CONTINUING MEDICAL EDUCATION (CME) QUESTIONS
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Destabilizing Ezh2 protein in alloreactive T cells by the Hsp90 inhibitor AUY922 leads to inhibition of inflammation in graft-versus-host disease target organs, such as the skin and liver. See the article by Huang et al on page 2737.
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