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Neurofilament light chain serum levels correlate with the severity of neurotoxicity after CAR T-cell treatment
Blinatumomab induces complete response in refractory PTLD after hematopoietic cell transplantation
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STIMULUS REPORT
Prognostic value of low-level MRD in adult acute lymphoblastic leukemia detected by low- and high-throughput methods
Michaela Kotrová,Johannes Koopmann,Heiko Trautmann,Nael Alakel,Joachim Beck,Kathrin Nachtkamp,Björn Steffen,Simon Raffel,Andreas Viardot,Klaus Wethmar,Nikos Darzentas,Claudia D. Baldus,Nicola Gökbuget,Monika Brüggemann
Neurofilament light chain serum levels correlate with the severity of neurotoxicity after CAR T-cell treatment
Clinical Trials & Observations
Florian Schoeberl,Steffen Tiedt,Anita Schmitt,Viktoria Blumenberg,Philipp Karschnia,Vanessa Granja Burbano,Veit L. Bücklein,Kai Rejeski,Christian Schmidt,Galina Busch,Michael von Bergwelt-Baildon,Jörg-Christian Tonn,Michael Schmitt,Marion Subklewe,Louisa von Baumgarten
G6b-B regulates an essential step in megakaryocyte maturation
Isabelle C. Becker,Zoltan Nagy,Georgi Manukjan,Melanie Haffner-Luntzer,Maximilian Englert,Tobias Heib,Timo Vögtle,Carina Gross,Richa Bharti,Sascha Dietrich,Kristina Mott,Johannes Heck,Sebastian Stegmaier,Anke Baranowsky,Thorsten Schinke,Nicolas Schlegel,Tobias Heckel,David Stegner,Irina Pleines,Anita Ignatius,Harald Schulze,Bernhard Nieswandt
MYELOID NEOPLASIA
Patient-specific MDS-RS iPSCs define the mis-spliced transcript repertoire and chromatin landscape of SF3B1-mutant HSPCs
Georgios Asimomitis,André G. Deslauriers,Andriana G. Kotini,Elsa Bernard,Davide Esposito,Malgorzata Olszewska,Nikolaos Spyrou,Juan Arango Ossa,Teresa Mortera-Blanco,Richard Koche,Yasuhito Nannya,Luca Malcovati,Seishi Ogawa,Mario Cazzola,Stuart A. Aaronson,Eva Hellström-Lindberg,Elli Papaemmanuil,Eirini P. Papapetrou
Characteristics and outcomes of patients with blastic plasmacytoid dendritic cell neoplasm treated with frontline HCVAD
Naveen Pemmaraju,Nathaniel R. Wilson,Guillermo Garcia-Manero,Koji Sasaki,Joseph D. Khoury,Nitin Jain,Gautam Borthakur,Farhad Ravandi,Naval Daver,Tapan Kadia,Courtney DiNardo,Elias Jabbour,Sherry Pierce,Muzaffar Qazilbash,Marina Konopleva,Hagop Kantarjian
Metalloproteinase inhibition reduces AML growth, prevents stem cell loss, and improves chemotherapy effectiveness
Chiara Pirillo,Flora Birch,Floriane S. Tissot,Sara Gonzalez Anton,Myriam Haltalli,Valentina Tini,Isabella Kong,Cécile Piot,Ben Partridge,Constandina Pospori,Karen Keeshan,Salvatore Santamaria,Edwin Hawkins,Brunangelo Falini,Andrea Marra,Delfim Duarte,Chiu Fan Lee,Edward Roberts,Cristina Lo Celso
Molecular and cytogenetic characterization of myelodysplastic syndromes in cell-free DNA
Nieves Garcia-Gisbert,Sara Garcia-Ávila,Brayan Merchán,Marta Salido,Concepción Fernández-Rodríguez,Joan Gibert,Lierni Fernández-Ibarrondo,Laura Camacho,Marta Lafuente,Raquel Longarón,Blanca Espinet,Patricia Vélez,Ramon M. Pujol,Marcio Andrade-Campos,Leonor Arenillas,Antonio Salar,Xavier Calvo,Carles Besses,Beatriz Bellosillo
RED CELLS, IRON, AND ERYTHROPOIESIS
THROMBOSIS AND HEMOSTASIS
Validation of the Khorana score for predicting venous thromboembolism in 40 218 patients with cancer initiating chemotherapy
Thure Filskov Overvad,Anne Gulbech Ording,Peter Brønnum Nielsen,Flemming Skjøth,Ida Ehlers Albertsen,Simon Noble,Anders Krog Vistisen,Inger Lise Gade,Marianne Tang Severinsen,Gregory Piazza,Torben Bjerregaard Larsen
TRANSPLANTATION
MicroRNA-31 regulates T-cell metabolism via HIF1α and promotes chronic GVHD pathogenesis in mice
Yongxia Wu,Corey Mealer,Steven Schutt,Carole L. Wilson,David Bastian,M. Hanief Sofi,Mengmeng Zhang,Zhenwu Luo,Hee-Jin Choi,Kaipo Yang,Linlu Tian,Hung Nguyen,Kris Helke,Lynn M. Schnapp,Honglin Wang,Xue-Zhong Yu
RESEARCH LETTER
Letermovir reduces chronic GVHD risk in calcineurin inhibitor-free GVHD prophylaxis after hematopoietic cell transplantation
Francesca Lorentino,Elisabetta Xue,Sara Mastaglio,Fabio Giglio,Daniela Clerici,Francesca Farina,Simona Piemontese,Alessandro Bruno,Lorenzo Lazzari,Annalisa Ruggeri,Elena Guggiari,Francesca Lunghi,Andrea A. Assanelli,Sarah Marktel,Magda Marcatti,Matteo G. Carrabba,Massimo Bernardi,Consuelo Corti,Jacopo Peccatori,Fabio Ciceri,Raffaella Greco,Maria Teresa Lupo-Stanghellini
Blinatumomab induces complete response in refractory PTLD after hematopoietic cell transplantation
Clinical Trials & Observations
Sanyukta Janardan,Edwin Horwitz,Benjamin Watkins,Kirsten Williams,Shanmuganathan Chandrakasan,Muna Qayed,Suhag Parikh,Staci Arnold,Frank Keller,Adina Alazraki,Michelle Schoettler,Kathryn Leung
Childhood acute myeloid leukemia with 5q deletion and HNRNPH1-MLLT10 fusion: the first case report
Ko Kudo,Yasuo Kubota,Tsutomu Toki,Rika Kanezaki,Akie Kobayashi,Tomohiko Sato,Takuya Kamio,Shinya Sasaki,Norio Shiba,Daisuke Tomizawa,Souichi Adachi,Kenichi Yoshida,Seishi Ogawa,Masafumi Seki,Junko Takita,Etsuro Ito,Kiminori Terui
A genetically distinct pediatric subtype of primary CNS large B-cell lymphoma is associated with favorable clinical outcome
Ekin Güney,Calixto-Hope G. Lucas,Zhongxia Qi,Jingwei Yu,Ruth Zhang,Robert S. Ohgami,James L. Rubenstein,Daniel R. Boué,Kristian Schafernak,Gerald B. Wertheim,Sonika Dahiya,Lisa Giulino-Roth,Andishe Attarbaschi,Matthew J. Barth,Shalin Kothari,Oussama Abla,Adam L. Cohen,Joe S. Mendez,Andrew Bollen,Arie Perry,Tarik Tihan,Melike Pekmezci,David A. Solomon,Kwun Wah Wen
ERRATUM
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Cover Image
Cover Image
Loss of microRNA-31 in donor T cells attenuates collagen deposition in recipient skin during development of chronic graft-versus-host disease. BALB/c mice were lethally irradiated and injected with bone marrow plus splenocytes isolated from B6 mice with or without microRNA-31 deficiency in T cells. Collagen deposition in recipient skin was evaluated with Masson’s trichrome stain on day 50 after bone marrow transplantation. See the article by Wu et al.
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