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Gautam Borthakur
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Journal Articles

Therapy-related chronic myelomonocytic leukemia does not have the high-risk features of a therapy-related neoplasm

Alex Bataller, Georgina Gener-Ricos, Emmanuel Almanza-Huante, Kelly S. Chien, Samuel Urrutia, Alexandre Bazinet, Juan Jose Rodriguez-Sevilla, Danielle Hammond, Koji Sasaki, Koichi Takahashi, Courtney D. DiNardo, Farhad Ravandi, Gautam Borthakur, Tapan M. Kadia, Rashmi Kanagal-Shamanna, Hagop M. Kantarjian, Guillermo Garcia-Manero, Guillermo Montalban-Bravo
Journal: Blood Advances
Blood Adv (2024) 8 (11): 2695–2706.
https://doi.org/10.1182/bloodadvances.2024012565
Published: 2024
Includes: Supplemental data
Journal Articles

Prognostic risk signature in patients with acute myeloid leukemia treated with hypomethylating agents and venetoclax

Clinical Trials & Observations
Alex Bataller, Alexandre Bazinet, Courtney D. DiNardo, Abhishek Maiti, Gautam Borthakur, Naval G. Daver, Nicholas J. Short, Elias J. Jabbour, Ghayas C. Issa, Naveen Pemmaraju, Musa Yilmaz, Guillermo Montalban-Bravo, Koichi Takahashi, Sanam Loghavi, Guillermo Garcia-Manero, Farhad Ravandi, Hagop M. Kantarjian, Tapan M. Kadia
Journal: Blood Advances
Blood Adv (2024) 8 (4): 927–935.
https://doi.org/10.1182/bloodadvances.2023011757
Published: 2024
Includes: Supplemental data
Journal Articles

A phase 1/2 study of mini-hyper-CVD plus venetoclax in patients with relapsed/refractory acute lymphoblastic leukemia

Clinical Trials & Observations
Nicholas J. Short, Elias Jabbour, Nitin Jain, Jayastu Senapati, Lewis Nasr, Fadi G. Haddad, Zhenhua Li, Yu-Chih Hsiao, Jun J. Yang, Naveen Pemmaraju, Maro Ohanian, William G. Wierda, Guillermo Montalban-Bravo, Gautam Borthakur, Lina Han, Lianchun Xiao, Xuelin Huang, Regina Abramova, Min Zhao, Rebecca Garris, Marina Konopleva, Farhad Ravandi, Hagop Kantarjian
Journal: Blood Advances
Blood Adv (2024) 8 (4): 909–915.
https://doi.org/10.1182/bloodadvances.2023012231
Published: 2024
Includes: Supplemental data
Journal Articles

Impact of type of induction therapy on outcomes in older adults with AML after allogeneic stem cell transplantation

Clinical Trials & Observations
Nicholas J. Short, Faustine Ong, Farhad Ravandi, Graciela Nogueras-Gonzalez, Tapan M. Kadia, Naval Daver, Courtney D. DiNardo, Marina Konopleva, Gautam Borthakur, Betul Oran, Gheath Al-Atrash, Rohtesh Mehta, Elias J. Jabbour, Musa Yilmaz, Ghayas C Issa, Abhishek Maiti, Richard E Champlin, Hagop Kantarjian, Elizabeth J Shpall, Uday Popat
Journal: Blood Advances
Blood Adv (2023) 7 (14): 3573–3581.
https://doi.org/10.1182/bloodadvances.2022009632
Published: 2023
Includes: Supplemental data
Journal Articles

Undetectable measurable residual disease is associated with improved outcomes in AML irrespective of treatment intensity

Alexandre Bazinet, Tapan Kadia, Nicholas J. Short, Gautam Borthakur, Sa A. Wang, Wei Wang, Sanam Loghavi, Jeffrey Jorgensen, Keyur Patel, Courtney DiNardo, Naval Daver, Yesid Alvarado, Fadi G. Haddad, Sherry Pierce, Graciela Nogueras Gonzalez, Abhishek Maiti, Koji Sasaki, Musa Yilmaz, Philip Thompson, William Wierda, Guillermo Garcia-Manero, Michael Andreeff, Elias Jabbour, Marina Konopleva, Xuelin Huang, Hagop Kantarjian, Farhad Ravandi
Journal: Blood Advances
Blood Adv (2023) 7 (13): 3284–3296.
https://doi.org/10.1182/bloodadvances.2022009391
Published: 2023
Includes: Supplemental data
Journal Articles

A global study for acute myeloid leukemia with RARG rearrangement

Hong-Hu Zhu, Ya-Zhen Qin, Zhang-Lin Zhang, Yong-Jing Liu, Li-Jun Wen, M. James You, Cheng Zhang, Esperanza Such, Hong Luo, Hong-Jian Yuan, Hong-Sheng Zhou, Hong-Xing Liu, Reng Xu, Ji Li, Jian-Hu Li, Jian-Ping Hao, Jie Jin, Liang Yu, Jing-Ying Zhang, Li-Ping Liu, Le-Ping Zhang, Rui-Bin Huang, Shu-Hong Shen, Su-Jun Gao, Wei Wang, Xiao-Jing Yan, Xin-You Zhang, Xin Du, Xiao-Xia Chu, Yan-Fang Yu, Yi Wang, Ying-Chang Mi, Ying Lu, Zhen Cai, Zhan Su, David Christopher Taussig, Suzanne MacMahon, Edward D. Ball, Huan-You Wang, John S. Welch, C. Cameron Yin, Gautam Borthakur, Miguel A. Sanz, Hagop M. Kantarjian, Jin-Yan Huang, Jiong Hu, Su-Ning Chen
Journal: Blood Advances
Blood Adv (2023) 7 (13): 2972–2982.
https://doi.org/10.1182/bloodadvances.2022008364
Published: 2023
Includes: Supplemental data
Journal Articles

Targeted therapy with the mutant IDH2 inhibitor enasidenib for high-risk IDH2 -mutant myelodysplastic syndrome

Clinical Trials & Observations
Courtney D. DiNardo, Sangeetha Venugopal, Curtis Lachowiez, Koichi Takahashi, Sanam Loghavi, Guillermo Montalban-Bravo, Xuemei Wang, Hetty Carraway, Mikkael Sekeres, Ameenah Sukkur, Danielle Hammond, Kelly Chien, Abhishek Maiti, Lucia Masarova, Koji Sasaki, Yesid Alvarado, Tapan Kadia, Nicholas J. Short, Naval Daver, Gautam Borthakur, Farhad Ravandi, Hagop M. Kantarjian, Bhumika Patel, Amy Dezern, Gail Roboz, Guillermo Garcia-Manero
Journal: Blood Advances
Blood Adv (2023) 7 (11): 2378–2387.
https://doi.org/10.1182/bloodadvances.2022008378
Published: 2023
Includes: Supplemental data
Journal Articles

A phase 2 study of nivolumab combined with ibrutinib in patients with diffuse large B-cell Richter transformation of CLL

Clinical Trials & Observations
Nitin Jain, Jayastu Senapati, Beenu Thakral, Alessandra Ferrajoli, Philip Thompson, Jan Burger, Sreyashi Basu, Tapan Kadia, Naval Daver, Gautam Borthakur, Marina Konopleva, Naveen Pemmaraju, Erin Parry, Catherine J. Wu, Joseph Khoury, Carlos Bueso-Ramos, Naveen Garg, Xuemei Wang, Wanda Lopez, Ana Ayala, Susan O’Brien, Hagop Kantarjian, Michael Keating, James Allison, Padmanee Sharma, William Wierda
Journal: Blood Advances
Blood Adv (2023) 7 (10): 1958–1966.
https://doi.org/10.1182/bloodadvances.2022008790
Published: 2023
Includes: Supplemental data
Journal Articles

Clinical outcomes associated with NPM1 mutations in patients with relapsed or refractory AML

Ghayas C. Issa, Aram Bidikian, Sangeetha Venugopal, Marina Konopleva, Courtney D. DiNardo, Tapan M. Kadia, Gautam Borthakur, Elias Jabbour, Naveen Pemmaraju, Musa Yilmaz, Nicholas J. Short, Abhishek Maiti, Koji Sasaki, Lucia Masarova, Sherry Pierce, Koichi Takahashi, Guilin Tang, Sanam Loghavi, Keyur Patel, Michael Andreeff, Kapil Bhalla, Guillermo Garcia-Manero, Farhad Ravandi, Hagop Kantarjian, Naval Daver
Journal: Blood Advances
Blood Adv (2023) 7 (6): 933–942.
https://doi.org/10.1182/bloodadvances.2022008316
Published: 2023
Includes: Supplemental data
Journal Articles

Validation of the ALFA-1200 model in older patients with AML treated with intensive chemotherapy

Clinical Trials & Observations
Hussein A. Abbas, Hanxiao Sun, Sherry Pierce, Rashmi Kanagal-Shamanna, Ziyi Li, Musa Yilmaz, Gautam Borthakur, Adam J. DiPippo, Elias Jabbour, Marina Konopleva, Nicholas J. Short, Courtney DiNardo, Naval Daver, Farhad Ravandi, Tapan M. Kadia
Journal: Blood Advances
Blood Adv (2023) 7 (5): 828–831.
https://doi.org/10.1182/bloodadvances.2022007172
Published: 2023
Includes: Supplemental data
Journal Articles

Validation of ALFA 1200 score in patients with AML >60 years treated with double nucleoside–based low-intensity therapy

Sangeetha Venugopal, Gautam Borthakur, Naval Daver, Courtney D. DiNardo, Naveen Pemmaraju, Nicholas J. Short, Hussein A. Abbas, Guillermo Garcia-Manero, Marina Konopleva, Farhad Ravandi, Tapan M. Kadia
Journal: Blood Advances
Blood Adv (2022) 6 (19): 5546–5549.
https://doi.org/10.1182/bloodadvances.2021006689
Published: 2022
Journal Articles

Characteristics and outcomes of patients with blastic plasmacytoid dendritic cell neoplasm treated with frontline HCVAD

Naveen Pemmaraju, Nathaniel R. Wilson, Guillermo Garcia-Manero, Koji Sasaki, Joseph D. Khoury, Nitin Jain, Gautam Borthakur, Farhad Ravandi, Naval Daver, Tapan Kadia, Courtney DiNardo, Elias Jabbour, Sherry Pierce, Muzaffar Qazilbash, Marina Konopleva, Hagop Kantarjian
Journal: Blood Advances
Blood Adv (2022) 6 (10): 3027–3035.
https://doi.org/10.1182/bloodadvances.2021006645
Published: 2022
Includes: Supplemental data
Journal Articles

Secondary cytogenetic abnormalities in core-binding factor AML harboring inv(16) vs t(8;21)

Se young Han, Krzysztof Mrózek, Jenna Voutsinas, Qian Wu, Elizabeth A. Morgan, Hanne Vestergaard, Robert Ohgami, Philip M. Kluin, Thomas Kielsgaard Kristensen, Sheeja Pullarkat, Michael Boe Møller, Ana-Iris Schiefer, Linda B. Baughn, Young Kim, David Czuchlewski, Jacobien R. Hilberink, Hans-Peter Horny, Tracy I. George, Michelle Dolan, Nam K. Ku, Cecilia Arana Yi, Vinod Pullarkat, Jessica Kohlschmidt, Amandeep Salhotra, Lori Soma, Clara D. Bloomfield, Dong Chen, Wolfgang R. Sperr, Guido Marcucci, Christina Cho, Cem Akin, Jason Gotlib, Sigurd Broesby-Olsen, Melissa Larson, Michael A. Linden, H. Joachim Deeg, Gregor Hoermann, Miguel-Angel Perales, Jason L. Hornick, Mark R. Litzow, Ryotaro Nakamura, Daniel Weisdorf, Gautam Borthakur, Gerwin Huls, Peter Valent, Celalettin Ustun, Cecilia C. S. Yeung
Journal: Blood Advances
Blood Adv (2021) 5 (10): 2481–2489.
https://doi.org/10.1182/bloodadvances.2020003605
Published: 2021
Includes: Supplemental data
Journal Articles

Single-center experience with venetoclax combinations in patients with newly diagnosed and relapsed AML evolving from MPNs

Clinical Trials & Observations
Lucia Masarova, Courtney D. DiNardo, Prithviraj Bose, Naveen Pemmaraju, Naval G. Daver, Tapan M. Kadia, Helen T. Chifotides, Lingsha Zhou, Gautam Borthakur, Zeev Estrov, Marina Konopleva, Srdan Verstovsek
Journal: Blood Advances
Blood Adv (2021) 5 (8): 2156–2164.
https://doi.org/10.1182/bloodadvances.2020003934
Published: 2021
Includes: Supplemental data
Journal Articles

Impact of splicing mutations in acute myeloid leukemia treated with hypomethylating agents combined with venetoclax

Clinical Trials & Observations
Curtis A. Lachowiez, Sanam Loghavi, Ken Furudate, Guillermo Montalban-Bravo, Abhishek Maiti, Tapan Kadia, Naval Daver, Gautam Borthakur, Naveen Pemmaraju, Koji Sasaki, Yesid Alvarado, Musa Yilmaz, Nicholas J. Short, Kelly Chien, Maro Ohanian, Sherry Pierce, Keyur P. Patel, Elias Jabbour, Farhad Ravandi, Hagop M. Kantarjian, Guillermo Garcia-Manero, Koichi Takahashi, Marina Y. Konopleva, Courtney D. DiNardo
Journal: Blood Advances
Blood Adv (2021) 5 (8): 2173–2183.
https://doi.org/10.1182/bloodadvances.2020004173
Published: 2021
Includes: Supplemental data
Journal Articles

Prognostic value of measurable residual disease after venetoclax and decitabine in acute myeloid leukemia

Clinical Trials & Observations
Abhishek Maiti, Courtney D. DiNardo, Sa A. Wang, Jeffrey Jorgensen, Tapan M. Kadia, Naval G. Daver, Nicholas J. Short, Musa Yilmaz, Naveen Pemmaraju, Gautam Borthakur, Prithviraj Bose, Ghayas C. Issa, Alessandra Ferrajoli, Elias J. Jabbour, Nitin Jain, Guillermo Garcia-Manero, Maro Ohanian, Koichi Takahashi, Guillermo Montalban-Bravo, Lucia Masarova, Jan A. Burger, Philip A. Thompson, Srdan Verstovsek, Koji Sasaki, Michael Andreeff, Caitlin R. Rausch, Kathryn S. Montalbano, Sherry Pierce, Wei Qiao, Jing Ning, Hagop M. Kantarjian, Marina Y. Konopleva, Farhad Ravandi
Journal: Blood Advances
Blood Adv (2021) 5 (7): 1876–1883.
https://doi.org/10.1182/bloodadvances.2020003717
Published: 2021
Includes: Supplemental data
Journal Articles

Clinical value of event-free survival in acute myeloid leukemia

Clinical Trials & Observations
Abhishek Maiti, Hagop M. Kantarjian, Vinita Popat, Gautam Borthakur, Guillermo Garcia-Manero, Marina Y. Konopleva, Courtney D. DiNardo, Srdan Verstovsek, Michael Andreeff, Tapan M. Kadia, Helen O. Ajufo, Rohit V. Goswamy, Carlos Blanco, Miguel Velasquez, Naval G. Daver, Naveen Pemmaraju, Sherry R. Pierce, William G. Wierda, Steven M. Kornblau, Farhad Ravandi, Jorge E. Cortes
Journal: Blood Advances
Blood Adv (2020) 4 (8): 1690–1699.
https://doi.org/10.1182/bloodadvances.2019001150
Published: 2020
Includes: Supplemental data
Journal Articles

Outcomes of older patients with NPM1-mutated AML: current treatments and the promise of venetoclax-based regimens

Clinical Trials & Observations
Curtis A. Lachowiez, Sanam Loghavi, Tapan M. Kadia, Naval Daver, Gautam Borthakur, Naveen Pemmaraju, Kiran Naqvi, Yesid Alvarado, Musa Yilmaz, Nicholas Short, Maro Ohanian, Sherry R. Pierce, Keyur P. Patel, Wei Qiao, Jing Ning, Koji Sasaki, Koichi Takahashi, Elias Jabbour, Michael Andreeff, Farhad Ravandi, Hagop M. Kantarjian, Marina Konopleva, Courtney D. DiNardo
Journal: Blood Advances
Blood Adv (2020) 4 (7): 1311–1320.
https://doi.org/10.1182/bloodadvances.2019001267
Published: 2020
Includes: Supplemental data
Journal Articles

Analysis of cardiovascular and arteriothrombotic adverse events in chronic-phase CML patients after frontline TKIs

Clinical Trials & Observations
Preetesh Jain, Hagop Kantarjian, Prajwal C. Boddu, Graciela M. Nogueras-González, Srdan Verstovsek, Guillermo Garcia-Manero, Gautam Borthakur, Koji Sasaki, Tapan M. Kadia, Princy Sam, Hycienth Ahaneku, Susan O’Brien, Zeev Estrov, Farhad Ravandi, Elias Jabbour, Jorge E. Cortes
Journal: Blood Advances
Blood Adv (2019) 3 (6): 851–861.
https://doi.org/10.1182/bloodadvances.2018025874
Published: 2019
Includes: Supplemental data
Journal Articles

Co-occurrence of FLT3 -TKD and NPM1 mutations defines a highly favorable prognostic AML group

Clinical Trials & Observations
Prajwal Boddu, Hagop Kantarjian, Gautam Borthakur, Tapan Kadia, Naval Daver, Sherry Pierce, Michael Andreeff, Farhad Ravandi, Jorge Cortes, Steven M. Kornblau
Journal: Blood Advances
Blood Adv (2017) 1 (19): 1546–1550.
https://doi.org/10.1182/bloodadvances.2017009019
Published: 2017
Includes: Supplemental data