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Jun J. Yang
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Journal Articles

Anti-leukemia efficacy of the dual BCL2/BCL-XL inhibitor AZD0466 in acute lymphoblastic leukemia preclinical models

Sankaranarayanan Kannan, Yizhen Li, Natalia Baran, Xu Yang, Sanaz Ghotbaldini, Qi Zhang Tatarata, Satoshi Yoshimura, Zhenhua Li, Yu-Chih Hsiao, Srividya B Balachander, Courtney L. Andersen, Justin Cidado, Jiyang Yu, Nitin Jain, Jun J. Yang, Marina Y. Konopleva
Journal: Blood Advances
Blood Adv bloodadvances.2024013423.
https://doi.org/10.1182/bloodadvances.2024013423
Published: 2024
Includes: Supplemental data
Journal Articles

A phase 1/2 study of mini-hyper-CVD plus venetoclax in patients with relapsed/refractory acute lymphoblastic leukemia

Clinical Trials & Observations
Nicholas J. Short, Elias Jabbour, Nitin Jain, Jayastu Senapati, Lewis Nasr, Fadi G. Haddad, Zhenhua Li, Yu-Chih Hsiao, Jun J. Yang, Naveen Pemmaraju, Maro Ohanian, William G. Wierda, Guillermo Montalban-Bravo, Gautam Borthakur, Lina Han, Lianchun Xiao, Xuelin Huang, Regina Abramova, Min Zhao, Rebecca Garris, Marina Konopleva, Farhad Ravandi, Hagop Kantarjian
Journal: Blood Advances
Blood Adv (2024) 8 (4): 909–915.
https://doi.org/10.1182/bloodadvances.2023012231
Published: 2024
Includes: Supplemental data
Journal Articles

ETV6 represses inflammatory response genes and regulates HSPC function during stress hematopoiesis in mice

Mackenzie Bloom, Ninad Oak, Rebekah Baskin-Doerfler, Ruopeng Feng, Ilaria Iacobucci, Pradyumna Baviskar, Xujie Zhao, Alexa N. Stroh, Chunliang Li, Patrick Ozark, Heather S. Tillman, Yichao Li, Katherine C. Verbist, Sabrin Albeituni, Danny C. Scott, Moeko T. King, Shannon L. McKinney-Freeman, Mitchell J. Weiss, Jun J. Yang, Kim E. Nichols
Journal: Blood Advances
Blood Adv (2023) 7 (18): 5608–5623.
https://doi.org/10.1182/bloodadvances.2022009313
Published: 2023
Includes: Supplemental data
Journal Articles

Identification of TCF3 germline variants in pediatric B-cell acute lymphoblastic leukemia

Carolin Escherich, Wenan Chen, Satoshi Miyamoto, Yui Namikawa, Wenjian Yang, David T. Teachey, Zhenhua Li, Elizabeth A. Raetz, Eric Larsen, Meenakshi Devidas, Paul L. Martin, W. Paul Bowman, Gang Wu, Ching-Hon Pui, Stephen P. Hunger, Mignon L. Loh, Masatoshi Takagi, Jun J. Yang
Journal: Blood Advances
Blood Adv (2023) 7 (10): 2177–2180.
https://doi.org/10.1182/bloodadvances.2022008563
Published: 2023
Includes: Supplemental data
Journal Articles

Amino acid stress response genes promote L-asparaginase resistance in pediatric acute lymphoblastic leukemia

Daniel C. Ferguson, J. Robert McCorkle, Kelly R. Barnett, Erik J. Bonten, Brennan P. Bergeron, Kashi Raj Bhattarai, Wenjian Yang, Colton Smith, Baranda S. Hansen, Richa Bajpai, Qian Dong, Robert J. Autry, Yoshihiro Gocho, Jonathan D. Diedrich, Kristine R. Crews, Shondra M. Pruett-Miller, Kathryn G. Roberts, Wendy Stock, Charles G. Mullighan, Hiroto Inaba, Sima Jeha, Ching-Hon Pui, Jun J. Yang, Mary V. Relling, William E. Evans, Daniel Savic
Journal: Blood Advances
Blood Adv (2022) 6 (11): 3386–3397.
https://doi.org/10.1182/bloodadvances.2022006965
Published: 2022
Includes: Supplemental data
Journal Articles

Genome-wide CRISPR/Cas9 screening identifies determinant of panobinostat sensitivity in acute lymphoblastic leukemia

Clinical Trials & Observations
Chuang Jiang, Maoxiang Qian, Yoshihiro Gocho, Wentao Yang, Guoqing Du, Shuhong Shen, Jun J. Yang, Hui Zhang
Journal: Blood Advances
Blood Adv (2022) 6 (8): 2496–2509.
https://doi.org/10.1182/bloodadvances.2021006152
Published: 2022
Includes: Supplemental data
Journal Articles

NUDT15 variants confer high incidence of second malignancies in children with acute lymphoblastic leukemia

Clinical Trials & Observations
Masanori Yoshida, Kazuhiko Nakabayashi, Wentao Yang, Aiko Sato-Otsubo, Shin-ichi Tsujimoto, Hiroko Ogata-Kawata, Tomoko Kawai, Keisuke Ishiwata, Mika Sakamoto, Kohji Okamura, Kaoru Yoshida, Ryota Shirai, Tomoo Osumi, Takaya Moriyama, Rina Nishii, Hiroyuki Takahashi, Chikako Kiyotani, Yoko Shioda, Keita Terashima, Sae Ishimaru, Yuki Yuza, Masatoshi Takagi, Yuki Arakawa, Akitoshi Kinoshita, Moeko Hino, Toshihiko Imamura, Daisuke Hasegawa, Yozo Nakazawa, Mayuko Okuya, Harumi Kakuda, Nao Takasugi, Akiko Inoue, Kentaro Ohki, Takako Yoshioka, Shuichi Ito, Daisuke Tomizawa, Katsuyoshi Koh, Kimikazu Matsumoto, Masashi Sanada, Nobutaka Kiyokawa, Akira Ohara, Seishi Ogawa, Atsushi Manabe, Akira Niwa, Kenichiro Hata, Jun J. Yang, Motohiro Kato
Journal: Blood Advances
Blood Adv (2021) 5 (23): 5420–5428.
https://doi.org/10.1182/bloodadvances.2021005507
Published: 2021
Includes: Supplemental data
Journal Articles

Distinct clinical characteristics of DUX4- and PAX5 -altered childhood B-lymphoblastic leukemia

Zhenhua Li, Shawn Hsien Ren Lee, Winnie Hui Ni Chin, Yi Lu, Nan Jiang, Evelyn Huizi Lim, Elaine Coustan-Smith, Kean Hui Chiew, Bernice Ling Zhi Oh, Grace Shimin Koh, Zhiwei Chen, Shirley Kow Yin Kham, Thuan Chong Quah, Hai Peng Lin, Ah Moy Tan, Hany Ariffin, Jun J. Yang, Allen Eng-Juh Yeoh
Journal: Blood Advances
Blood Adv (2021) 5 (23): 5226–5238.
https://doi.org/10.1182/bloodadvances.2021004895
Published: 2021
Includes: Supplemental data