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Nitin Jain
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Journal Articles

Anti-leukemia efficacy of the dual BCL2/BCL-XL inhibitor AZD0466 in acute lymphoblastic leukemia preclinical models

Sankaranarayanan Kannan, Yizhen Li, Natalia Baran, Xu Yang, Sanaz Ghotbaldini, Qi Zhang Tatarata, Satoshi Yoshimura, Zhenhua Li, Yu-Chih Hsiao, Srividya B Balachander, Courtney L. Andersen, Justin Cidado, Jiyang Yu, Nitin Jain, Jun J. Yang, Marina Y. Konopleva
Journal: Blood Advances
Blood Adv bloodadvances.2024013423.
https://doi.org/10.1182/bloodadvances.2024013423
Published: 2024
Includes: Supplemental data
Journal Articles

Venetoclax plus low intensity chemotherapy for adults with acute lymphoblastic leukemia

Clinical Trials & Observations
Marlise R. Luskin, Shai Shimony, Julia H. Keating, Eric S Winer, Jacqueline S. Garcia, Richard M. Stone, Elias J. Jabbour, Yael Flamand, Kristen Stevenson, Jeremy Adam Ryan, Zhihong Zeng, Anthony Letai, Marina Y. Konopleva, Nitin Jain, Daniel J DeAngelo
Journal: Blood Advances
Blood Adv bloodadvances.2024014405.
https://doi.org/10.1182/bloodadvances.2024014405
Published: 2024
Includes: Supplemental data
Journal Articles

A multicenter study of venetoclax-based treatment for patients with Richter transformation of chronic lymphocytic leukemia

Clinical Trials & Observations
Paul J. Hampel, Mahesh Swaminathan, Kerry A. Rogers, Erin M. Parry, Jan A. Burger, Matthew S. Davids, Wei Ding, Alessandra Ferrajoli, Jonathan M. Hyak, Nitin Jain, Saad S. Kenderian, Yucai Wang, William G. Wierda, Jennifer A. Woyach, Sameer A. Parikh, Philip A. Thompson
Journal: Blood Advances
Blood Adv (2024) 8 (10): 2342–2350.
https://doi.org/10.1182/bloodadvances.2023012080
Published: 2024
Includes: Supplemental data
Journal Articles

A phase 1/2 study of mini-hyper-CVD plus venetoclax in patients with relapsed/refractory acute lymphoblastic leukemia

Clinical Trials & Observations
Nicholas J. Short, Elias Jabbour, Nitin Jain, Jayastu Senapati, Lewis Nasr, Fadi G. Haddad, Zhenhua Li, Yu-Chih Hsiao, Jun J. Yang, Naveen Pemmaraju, Maro Ohanian, William G. Wierda, Guillermo Montalban-Bravo, Gautam Borthakur, Lina Han, Lianchun Xiao, Xuelin Huang, Regina Abramova, Min Zhao, Rebecca Garris, Marina Konopleva, Farhad Ravandi, Hagop Kantarjian
Journal: Blood Advances
Blood Adv (2024) 8 (4): 909–915.
https://doi.org/10.1182/bloodadvances.2023012231
Published: 2024
Includes: Supplemental data
Journal Articles

Chimeric antigen receptor T-cell therapy for adult B-cell acute lymphoblastic leukemia: state-of-the-(C)ART and the road ahead

Oren Pasvolsky, Partow Kebriaei, Bijal D. Shah, Elias Jabbour, Nitin Jain
Journal: Blood Advances
Blood Adv (2023) 7 (14): 3350–3360.
https://doi.org/10.1182/bloodadvances.2022009462
Published: 2023
Journal Articles

BH3 profiling identifies BCL-2 dependence in adult patients with early T-cell progenitor acute lymphoblastic leukemia

Elyse A. Olesinski, Karanpreet S. Bhatia, Aarthi N. Mahesh, Shazwina Rosli, Jameelah S. Mohamed, Wei Y. Jen, Nitin Jain, Jacqueline S. Garcia, Gee C. Wong, Melissa Ooi, Anthony Letai, Marina Konopleva, Shruti Bhatt
Journal: Blood Advances
Blood Adv (2023) 7 (12): 2917–2923.
https://doi.org/10.1182/bloodadvances.2022007728
Published: 2023
Includes: Supplemental data
Journal Articles

A phase 2 study of nivolumab combined with ibrutinib in patients with diffuse large B-cell Richter transformation of CLL

Clinical Trials & Observations
Nitin Jain, Jayastu Senapati, Beenu Thakral, Alessandra Ferrajoli, Philip Thompson, Jan Burger, Sreyashi Basu, Tapan Kadia, Naval Daver, Gautam Borthakur, Marina Konopleva, Naveen Pemmaraju, Erin Parry, Catherine J. Wu, Joseph Khoury, Carlos Bueso-Ramos, Naveen Garg, Xuemei Wang, Wanda Lopez, Ana Ayala, Susan O’Brien, Hagop Kantarjian, Michael Keating, James Allison, Padmanee Sharma, William Wierda
Journal: Blood Advances
Blood Adv (2023) 7 (10): 1958–1966.
https://doi.org/10.1182/bloodadvances.2022008790
Published: 2023
Includes: Supplemental data
Journal Articles

High-sensitivity next-generation sequencing MRD assessment in ALL identifies patients at very low risk of relapse

Nicholas J. Short, Hagop Kantarjian, Farhad Ravandi, Marina Konopleva, Nitin Jain, Rashmi Kanagal-Shamanna, Keyur P. Patel, Walid Macaron, Tapan M. Kadia, Sa Wang, Jeffrey L. Jorgensen, Joseph D. Khoury, Musa Yilmaz, Partow Kebriaei, Koichi Takahashi, Guillermo Garcia-Manero, Naval Daver, Sean M. Post, Xuelin Huang, Steven M. Kornblau, Sara Pelletier, Wilmer Flores, Jairo Matthews, Rebecca Garris, Elias Jabbour
Journal: Blood Advances
Blood Adv (2022) 6 (13): 4006–4014.
https://doi.org/10.1182/bloodadvances.2022007378
Published: 2022
Includes: Supplemental data
Journal Articles

Characteristics and outcomes of patients with blastic plasmacytoid dendritic cell neoplasm treated with frontline HCVAD

Naveen Pemmaraju, Nathaniel R. Wilson, Guillermo Garcia-Manero, Koji Sasaki, Joseph D. Khoury, Nitin Jain, Gautam Borthakur, Farhad Ravandi, Naval Daver, Tapan Kadia, Courtney DiNardo, Elias Jabbour, Sherry Pierce, Muzaffar Qazilbash, Marina Konopleva, Hagop Kantarjian
Journal: Blood Advances
Blood Adv (2022) 6 (10): 3027–3035.
https://doi.org/10.1182/bloodadvances.2021006645
Published: 2022
Includes: Supplemental data
Journal Articles

Outcomes of acute lymphoblastic leukemia with KMT2A ( MLL ) rearrangement: the MD Anderson experience

Clinical Trials & Observations
Guillaume Richard-Carpentier, Hagop M. Kantarjian, Guilin Tang, C. Cameron Yin, Joseph D. Khoury, Ghayas C. Issa, Fadi Haddad, Nitin Jain, Farhad Ravandi, Nicholas J. Short, Courtney D. DiNardo, Koichi Takahashi, Marina Y. Konopleva, Naval G. Daver, Tapan Kadia, Guillermo Garcia-Manero, Rebecca Garris, Susan O’Brien, Elias Jabbour
Journal: Blood Advances
Blood Adv (2021) 5 (23): 5415–5419.
https://doi.org/10.1182/bloodadvances.2021004580
Published: 2021
Journal Articles

Long-term outcome of hyper-CVAD-R for Burkitt leukemia/lymphoma and high-grade B-cell lymphoma: focus on CNS relapse

Clinical Trials & Observations
Bachar Samra, Joseph D. Khoury, Kiyomi Morita, Farhad Ravandi, Guillaume Richard-Carpentier, Nicholas J. Short, Siba El Hussein, Philip Thompson, Nitin Jain, Hagop Kantarjian, Elias Jabbour
Journal: Blood Advances
Blood Adv (2021) 5 (20): 3913–3918.
https://doi.org/10.1182/bloodadvances.2021004427
Published: 2021
Includes: Supplemental data
Journal Articles

Final results of a phase 2 clinical trial of LCL161, an oral SMAC mimetic for patients with myelofibrosis

Clinical Trials & Observations
Naveen Pemmaraju, Bing Z. Carter, Prithviraj Bose, Nitin Jain, Tapan M. Kadia, Guillermo Garcia-Manero, Carlos E. Bueso-Ramos, Courtney D. DiNardo, Sharon Bledsoe, Naval G. Daver, Uday Popat, Marina Y. Konopleva, Lingsha Zhou, Sherry Pierce, Zeev E. Estrov, Gautam M. Borthakur, Maro Ohanian, Wei Qiao, Lucia Masarova, Xuemei Wang, Po Yee Mak, Jorge Cortes, Elias Jabbour, Srdan Verstovsek
Journal: Blood Advances
Blood Adv (2021) 5 (16): 3163–3173.
https://doi.org/10.1182/bloodadvances.2020003829
Published: 2021
Journal Articles

Prognostic value of measurable residual disease after venetoclax and decitabine in acute myeloid leukemia

Clinical Trials & Observations
Abhishek Maiti, Courtney D. DiNardo, Sa A. Wang, Jeffrey Jorgensen, Tapan M. Kadia, Naval G. Daver, Nicholas J. Short, Musa Yilmaz, Naveen Pemmaraju, Gautam Borthakur, Prithviraj Bose, Ghayas C. Issa, Alessandra Ferrajoli, Elias J. Jabbour, Nitin Jain, Guillermo Garcia-Manero, Maro Ohanian, Koichi Takahashi, Guillermo Montalban-Bravo, Lucia Masarova, Jan A. Burger, Philip A. Thompson, Srdan Verstovsek, Koji Sasaki, Michael Andreeff, Caitlin R. Rausch, Kathryn S. Montalbano, Sherry Pierce, Wei Qiao, Jing Ning, Hagop M. Kantarjian, Marina Y. Konopleva, Farhad Ravandi
Journal: Blood Advances
Blood Adv (2021) 5 (7): 1876–1883.
https://doi.org/10.1182/bloodadvances.2020003717
Published: 2021
Includes: Supplemental data
Journal Articles

Incidental Richter transformation in chronic lymphocytic leukemia patients during temporary interruption of ibrutinib

Paul J. Hampel, Hua-Jay J. Cherng, Timothy G. Call, Wei Ding, Mahsa Khanlari, Ellen D. McPhail, Roberto N. Miranda, Pei Lin, Hussein A. Tawbi, Alessandra Ferrajoli, William G. Wierda, Nitin Jain, Sameer A. Parikh
Journal: Blood Advances
Blood Adv (2020) 4 (18): 4508–4511.
https://doi.org/10.1182/bloodadvances.2020002454
Published: 2020
Includes: Supplemental data
Journal Articles

A phase 1 study of azacitidine with high-dose cytarabine and mitoxantrone in high-risk acute myeloid leukemia

Clinical Trials & Observations
Kirk E. Cahill, Yasmin H. Karimi, Theodore G. Karrison, Nitin Jain, Margaret Green, Howard Weiner, Noreen Fulton, Sabah Kadri, Lucy A. Godley, Andrew S. Artz, Hongtao Liu, Michael J. Thirman, Michelle M. Le Beau, Megan E. McNerney, Jeremy Segal, Richard A. Larson, Wendy Stock, Olatoyosi Odenike
Journal: Blood Advances
Blood Adv (2020) 4 (4): 599–606.
https://doi.org/10.1182/bloodadvances.2019000795
Published: 2020
Includes: Supplemental data
Journal Articles

Loncastuximab tesirine, an anti-CD19 antibody-drug conjugate, in relapsed/refractory B-cell acute lymphoblastic leukemia

Clinical Trials & Observations
Nitin Jain, Wendy Stock, Amer Zeidan, Ehab Atallah, James McCloskey, Leonard Heffner, Benjamin Tomlinson, Bhavana Bhatnagar, Jay Feingold, David Ungar, Grace Chao, Xiaoyan Zhang, Yajuan Qin, Karin Havenith, Hagop Kantarjian, Matthew J. Wieduwilt
Journal: Blood Advances
Blood Adv (2020) 4 (3): 449–457.
https://doi.org/10.1182/bloodadvances.2019000767
Published: 2020
Includes: Supplemental data
Journal Articles

Efficacy and predictors of response of lenalidomide and rituximab in patients with treatment-naive and relapsed CLL

Clinical Trials & Observations
Paolo Strati, Koichi Takahashi, Christine B. Peterson, Michael J. Keating, Philip A. Thompson, Naval G. Daver, Nitin Jain, Jan A. Burger, Zeev Estrov, Susan M. O'Brien, Hagop M. Kantarjian, William G. Wierda, P. Andrew Futreal, Alessandra Ferrajoli
Journal: Blood Advances
Blood Adv (2019) 3 (9): 1533–1539.
https://doi.org/10.1182/bloodadvances.2019031336
Published: 2019