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Issue Archive

Volume 5, Issue 6
March 23 2021
Issue Cover

Table of Contents

REVIEW ARTICLE

Immunotherapy perspectives in the new era of B-cell editing
Natsuko Ueda,Marine Cahen,Yannic Danger,Jérôme Moreaux,Christophe Sirac,Michel Cogné
View Articletitled, Immunotherapy perspectives in the new era of B-cell editing

CLINICAL TRIALS AND OBSERVATIONS

Safety and reactogenicity of the recombinant zoster vaccine after allogeneic hematopoietic cell transplantation
Clinical Trials & Observations
Emily Baumrin,Natalie E. Izaguirre,Bruce Bausk,Monica M. Feeley,Camden P. Bay,Qiheng Yang,Vincent T. Ho,Lindsey R. Baden,Nicolas C. Issa
View Articletitled, Safety and reactogenicity of the recombinant zoster vaccine after allogeneic hematopoietic cell transplantation
Supplemental data
Unmarried or less-educated patients with mantle cell lymphoma are less likely to undergo a transplant, leading to lower survival
Clinical Trials & Observations
Ingrid Glimelius,Karin E. Smedby,Alexandra Albertsson-Lindblad,Michael J. Crowther,Sandra Eloranta,Mats Jerkeman,Caroline E. Weibull
View Articletitled, Unmarried or less-educated patients with mantle cell lymphoma are less likely to undergo a transplant, leading to lower survival
Supplemental data
Older adults with newly diagnosed high-risk/secondary AML who achieved remission with CPX-351: phase 3 post hoc analyses
Clinical Trials & Observations
Tara L. Lin,David A. Rizzieri,Daniel H. Ryan,Gary J. Schiller,Jonathan E. Kolitz,Geoffrey L. Uy,Donna E. Hogge,Scott R. Solomon,Matthew J. Wieduwilt,Robert J. Ryan,Stefan Faderl,Jorge E. Cortes,Jeffrey E. Lancet
View Articletitled, Older adults with newly diagnosed high-risk/secondary AML who achieved remission with CPX-351: phase 3 post hoc analyses
Supplemental data
Rheumatologic diseases impact the risk of progression of MGUS to overt multiple myeloma
Clinical Trials & Observations
Normann Steiner,Georg Göbel,Daniela Michaeler,Anna-Luise Platz,Wolfgang Prokop,Anna Maria Wolf,Dominik Wolf,Christina Duftner,Eberhard Gunsilius
View Articletitled, Rheumatologic diseases impact the risk of progression of MGUS to overt multiple myeloma
Supplemental data

HEMATOPOIESIS AND STEM CELLS

Autophagy is dispensable for the maintenance of hematopoietic stem cells in neonates
Michihiro Hashimoto,Terumasa Umemoto,Ayako Nakamura-Ishizu,Takayoshi Matsumura,Tomomasa Yokomizo,Maiko Sezaki,Hitoshi Takizawa,Toshio Suda
View Articletitled, Autophagy is dispensable for the maintenance of hematopoietic stem cells in neonates
Supplemental data
Using mitochondrial activity to select for potent human hematopoietic stem cells
Jiajing Qiu,Jana Gjini,Tasleem Arif,Kateri Moore,Miao Lin,Saghi Ghaffari
View Articletitled, Using mitochondrial activity to select for potent human hematopoietic stem cells
Supplemental data

IMMUNOBIOLOGY AND IMMUNOTHERAPY

Cytokine release syndrome and neurological event costs in lisocabtagene maraleucel–treated patients in the TRANSCEND NHL 001 trial
Jeremy S. Abramson,Tanya Siddiqi,Jacob Garcia,Christine Dehner,Yeonhee Kim,Andy Nguyen,Sophie Snyder,November McGarvey,Matthew Gitlin,Corey Pelletier,Monika P. Jun
View Articletitled, Cytokine release syndrome and neurological event costs in lisocabtagene maraleucel–treated patients in the TRANSCEND NHL 001 trial

LYMPHOID NEOPLASIA

Autologous stem cell transplantation after anti-PD-1 therapy for multiply relapsed or refractory Hodgkin lymphoma
Clinical Trials & Observations
Reid W. Merryman,Robert A. Redd,Taiga Nishihori,Julio Chavez,Yago Nieto,Justin M. Darrah,Uttam Rao,Michael T. Byrne,David A. Bond,Kami J. Maddocks,Michael A. Spinner,Ranjana H. Advani,Hatcher J. Ballard,Jakub Svoboda,Anurag K. Singh,Joseph P. McGuirk,Dipenkumar Modi,Radhakrishnan Ramchandren,Jason Romancik,Jonathon B. Cohen,Matthew J. Frigault,Yi-Bin Chen,Anthony V. Serritella,Justine Kline,Stephen Ansell,Sunita Nathan,Maryam Rahimian,Robin M. Joyce,Mansi Shah,Kevin A. David,Steven Park,Anne W. Beaven,Alma Habib,Veronika Bachanova,Shazia Nakhoda,Nadia Khan,Ryan C. Lynch,Stephen D. Smith,Vincent T. Ho,Ann LaCasce,Philippe Armand,Alex F. Herrera
View Articletitled, Autologous stem cell transplantation after anti-PD-1 therapy for multiply relapsed or refractory Hodgkin lymphoma
Supplemental data
Characteristics and outcomes of KSHV-associated multicentric Castleman disease with or without other KSHV diseases
Clinical Trials & Observations
Ramya Ramaswami,Kathryn Lurain,Mark N. Polizzotto,Irene Ekwede,Kirsta Waldon,Seth M. Steinberg,Ralph Mangusan,Anaida Widell,Adam Rupert,Jomy George,Priscila H. Gonçalves,Vickie A. Marshall,Denise Whitby,Hao-Wei Wang,Stefania Pittaluga,Elaine S. Jaffe,Richard F. Little,Thomas S. Uldrick,Robert Yarchoan
View Articletitled, Characteristics and outcomes of KSHV-associated multicentric Castleman disease with or without other KSHV diseases
Supplemental data
Revisiting IL-6 expression in the tumor microenvironment of classical Hodgkin lymphoma
Alex Reza Gholiha,Peter Hollander,Ingrid Glimelius,Gustaf Hedstrom,Daniel Molin,Henrik Hjalgrim,Karin E. Smedby,Jamileh Hashemi,Rose-Marie Amini,Gunilla Enblad
View Articletitled, Revisiting IL-6 expression in the tumor microenvironment of classical Hodgkin lymphoma
Supplemental data
Outcomes of older patients with follicular lymphoma using individual data from 5922 patients in 18 randomized controlled trials
Clinical Trials & Observations
Carla Casulo,Jesse G. Dixon,Fang-Shu Ou,Eva Hoster,Bruce A. Peterson,Howard S. Hochster,Pauline Brice,Marco Ladetto,Wolfgang Hiddemann,Robert Marcus,Eva Kimby,Michael Herold,Tina Nielsen,Franck Morschhauser,Mathias Rummel,Anton Hagenbeek,Umberto Vitolo,Gilles A. Salles,Qian Shi,Christopher R. Flowers,on behalf of the FLASH group
View Articletitled, Outcomes of older patients with follicular lymphoma using individual data from 5922 patients in 18 randomized controlled trials

PLATELETS AND THROMBOPOIESIS

Misdiagnosed thrombocytopenia in children and adolescents: analysis of the Pediatric and Adult Registry on Chronic ITP
Clinical Trials & Observations
Alexandra Schifferli,Andrea Heiri,Paul Imbach,Susanne Holzhauer,Markus G. Seidel,Diane Nugent,Marc Michel,Thomas Kühne
View Articletitled, Misdiagnosed thrombocytopenia in children and adolescents: analysis of the Pediatric and Adult Registry on Chronic ITP
Dissecting pathways to thrombocytopenia in a mouse model of visceral leishmaniasis
Gulab Fatima Rani,Olivier Preham,Helen Ashwin,Najmeeyah Brown,Ian S. Hitchcock,Paul M. Kaye
View Articletitled, Dissecting pathways to thrombocytopenia in a mouse model of visceral leishmaniasis
Supplemental data
Mitochondrial dynamics and reactive oxygen species initiate thrombopoiesis from mature megakaryocytes
Sonia Poirault-Chassac,Valérie Nivet-Antoine,Amandine Houvert,Alexandre Kauskot,Evelyne Lauret,René Lai-Kuen,Isabelle Dusanter-Fourt,Dominique Baruch
View Articletitled, Mitochondrial dynamics and reactive oxygen species initiate thrombopoiesis from mature megakaryocytes
Supplemental data

THROMBOSIS AND HEMOSTASIS

Glioblastoma cell populations with distinct oncogenic programs release podoplanin as procoagulant extracellular vesicles
Nadim Tawil,Rayhaan Bassawon,Brian Meehan,Ali Nehme,Laura Montermini,Tenzin Gayden,Nicolas De Jay,Cristiana Spinelli,Shilpa Chennakrishnaiah,Dongsic Choi,Lata Adnani,Michele Zeinieh,Nada Jabado,Claudia L. Kleinman,Michael Witcher,Yasser Riazalhosseini,Nigel S. Key,David Schiff,Steven P. Grover,Nigel Mackman,Charles P. Couturier,Kevin Petrecca,Mario L. Suvà,Anoop Patel,Itay Tirosh,Hamed Najafabadi,Janusz Rak
View Articletitled, Glioblastoma cell populations with distinct oncogenic programs release podoplanin as procoagulant extracellular vesicles
Supplemental data

TRANSPLANTATION

A prognostic score including mutation profile and clinical features for patients with CMML undergoing stem cell transplantation
Clinical Trials & Observations
Nico Gagelmann,Anita Badbaran,Dietrich W. Beelen,Rachel B. Salit,Friedrich Stölzel,Christina Rautenberg,Heiko Becker,Aleksandar Radujkovic,Victoria Panagiota,Rashit Bogdanov,Maximilian Christopeit,Yong Park,Olivier Nibourel,Thomas Luft,Michael Koldehoff,Maarten Corsten,Michael Heuser,Jürgen Finke,Guido Kobbe,Uwe Platzbecker,Marie Robin,Bart L. Scott,Nicolaus Kröger
View Articletitled, A prognostic score including mutation profile and clinical features for patients with CMML undergoing stem cell transplantation
Supplemental data

COMMENTARIES

Early progression of disease in follicular lymphoma is a robust correlate but not a surrogate for overall survival
Clinical Trials & Observations
Emmanuel Bachy,James R. Cerhan,Gilles Salles
View Articletitled, Early progression of disease in follicular lymphoma is a robust correlate but not a surrogate for overall survival
Supplemental data
Clonal evolution and heterogeneity in advanced systemic mastocytosis revealed by single-cell DNA sequencing
Ken-Hong Lim,Jo-Ning Wu,To-Yu Huang,Jie-Yang Jhuang,Yu-Cheng Chang,Huan-Chau Lin,Yi-Hao Chiang,Ying-Wen Su,Caleb Gon-Shen Chen,Yi-Fang Chang,Johnson Lin
View Articletitled, Clonal evolution and heterogeneity in advanced systemic mastocytosis revealed by single-cell DNA sequencing
Supplemental data
Azacitidine maintenance after allogeneic hematopoietic cell transplantation for MDS and AML
Clinical Trials & Observations
Firas El Chaer,Uma Borate,Rémy Duléry,Shernan G. Holtan,Arjun Datt Law,Lori Muffly,Samah Nassereddine,Rory M. Shallis,Kate Stringaris,Justin Taylor,Steven M. Devine,Mohamad Mohty,Christopher S. Hourigan
View Articletitled, Azacitidine maintenance after allogeneic hematopoietic cell transplantation for MDS and AML

ERRATUM

Oran B, de Lima M, Garcia-Manero G, et al. A phase 3 randomized study of 5-azacitidine maintenance vs observation after transplant in high-risk AML and MDS patients. Blood Adv. 2020;4(21):5580-5588.
View Articletitled, Oran B, de Lima M, Garcia-Manero G, et al. A phase 3 randomized study of 5-azacitidine maintenance vs observation after transplant in high-risk AML and MDS patients. <em>Blood Adv.</em> 2020;4(21):5580-5588.
  • Cover Image

    Cover Image

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    COVER FIGURE
    Changes in the mitochondrial network during thrombopoiesis. A mature intermediate megakaryocyte characterized by loss of roundness displays small mitochondria, shown by fluorescence microscopy upon MitoTracker (red) and α-tubulin (green) labeling, which contribute to thrombopoiesis initiation. See the article by Poirault-Chassac et al.

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