1-20 of 2020
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Journal Articles

Platelet activation and platelet-monocyte aggregate formation trigger tissue factor expression in patients with severe COVID-19

Eugenio D. Hottz, Isaclaudia G. Azevedo-Quintanilha, Lohanna Palhinha, Lívia Teixeira, Ester A. Barreto, Camila R. R. Pão, Cassia Righy, Sérgio Franco, Thiago M. L. Souza, Pedro Kurtz, Fernando A. Bozza, Patrícia T. Bozza
Journal: Blood
Blood (2020) 136 (11): 1330–1341.
https://doi.org/10.1182/blood.2020007252
Published: 2020
Includes: Supplemental data
Journal Articles

Talin-1 is the principal platelet Rap1 effector of integrin activation

Frederic Lagarrigue, David S. Paul, Alexandre R. Gingras, Andrew J. Valadez, Hao Sun, Jenny Lin, Monica N. Cuevas, Jailal N. Ablack, Miguel Alejandro Lopez-Ramirez, Wolfgang Bergmeier, Mark H. Ginsberg
Journal: Blood
Blood (2020) 136 (10): 1180–1190.
https://doi.org/10.1182/blood.2020005348
Published: 2020
Includes: Supplemental data
Journal Articles

The 14-3-3ζ–c-Src–integrin-β3 complex is vital for platelet activation

Chuanbin Shen, Ming Liu, Runjia Xu, Gan Wang, June Li, Pingguo Chen, Wenjing Ma, James Mwangi, Qiumin Lu, Zilei Duan, Zhiye Zhang, Fatima Zohra Dahmani, Daniel Thomas Mackeigan, Heyu Ni, Ren Lai
Journal: Blood
Blood (2020) 136 (8): 974–988.
https://doi.org/10.1182/blood.2019002314
Published: 2020
Includes: Supplemental data
Journal Articles

Integrin α6 mediates the drug resistance of acute lymphoblastic B-cell leukemia

Eun Ji Gang, Hye Na Kim, Yao-Te Hsieh, Yongsheng Ruan, Heather A. Ogana, Solomon Lee, Jennifer Pham, Huimin Geng, Eugene Park, Lars Klemm, Cheryl L. Willman, William L. Carroll, Steven D. Mittelman, Etan Orgel, Matthew J. Oberley, Chintan Parekh, Hisham Abdel-Azim, Deepa Bhojwani, Alan S. Wayne, Adèle De Arcangelis, Elisabeth Georges-Labouesse, Elizabeth Wayner, Halvard Bonig, Aspram Minasyan, Johanna ten Hoeve, Thomas G. Graeber, Markus Müschen, Nora Heisterkamp, Yong-Mi Kim
Journal: Blood
Blood (2020) 136 (2): 210–223.
https://doi.org/10.1182/blood.2019001417
Published: 2020
Includes: Supplemental data
Journal Articles

Adhesion to fibronectin via α5β1 integrin supports expansion of the megakaryocyte lineage in primary myelofibrosis

Brief Report
Shinobu Matsuura, Cristal Reyna Thompson, Seng Kah Ng, Christina Marie Ward, Aikaterini Karagianni, Carla Mazzeo, Alessandro Malara, Alessandra Balduini, Katya Ravid
Journal: Blood
Blood (2020) 135 (25): 2286–2291.
https://doi.org/10.1182/blood.2019004230
Published: 2020
Includes: Supplemental data
Journal Articles

Integrin α9β1: a new target to fight thrombosis

Alexander Brill
Journal: Blood
Blood (2020) 135 (11): 787–788.
https://doi.org/10.1182/blood.2020004999
Published: 2020
Journal Articles

Targeting myeloid-cell specific integrin α9β1 inhibits arterial thrombosis in mice

Brief Report
Nirav Dhanesha, Manasa K. Nayak, Prakash Doddapattar, Manish Jain, Gagan D. Flora, Shigeyuki Kon, Anil K. Chauhan
Journal: Blood
Blood (2020) 135 (11): 857–861.
https://doi.org/10.1182/blood.2019002846
Published: 2020
Includes: Supplemental data
Journal Articles

Activation and suppression of hematopoietic integrins in hemostasis and immunity

Martijn A. Nolte, Coert Margadant
Journal: Blood
Blood (2020) 135 (1): 7–16.
https://doi.org/10.1182/blood.2019003336
Published: 2020
Journal Articles

Adhesion-Mediated Multiple Myeloma (MM) Disease Progression: Junctional Adhesion Molecule a Enhances Angiogenesis and Multiple Myeloma Dissemination and Predicts Poor Survival

Antonio Giovanni Solimando, MD, Matteo Claudio Da Via', MD, Patrizia Leone, Giorgio Croci, Paola Borrelli, Paula Tabares Gaviria, Andreas Brandl, PhD, Giuseppe Di Lernia, Francesco Paolo Bianchi, Silvio Tafuri, Umair Munawar, MSc, Torsten Steinbrunn, Alessandra Balduini, MD, Assunta Melaccio, Hilka Rauert-Wunderlich, Katharina Schmiedgen, Hannah Manz, Paolo Ditonno, Roberto Ria, MD, Erik Henke, Carolina Terragna, Wolfram Klapper, Nora Trinks, Ulrich Terpitz, Giacomo Corleone, Leo Rasche, MD, Andreas Rosenwald, MD, Martin Kortuem, Michele Cavo, Domenico Ribatti, MD, Vito Racanelli, Hermann Einsele, MD, Angelo Vacca, MD PhD, Andreas Beilhack, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 855.
https://doi.org/10.1182/blood-2019-126674
Published: 2019
Journal Articles

Evaluation of Efficacy and Safety of Cold-Stored Platelets in Healthy Human Subjects Treated with Dual Antiplatelet Therapy

Jeffrey Miles, M.S., Shawn Lawrence Bailey, BS, Lydia Fang, M.S., Barbara Osborne, RN, Jill Corson, RN, Johnathan P. Mack, MD, Moritz Stolla, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 718.
https://doi.org/10.1182/blood-2019-124122
Published: 2019
Journal Articles

The Role of Gα 13 in Integrin β 2 -Dependent Neutrophil Transendothelial Migration

Claire W Chang, BS, Ni Cheng, PhD, Xiaoping Du, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1037.
https://doi.org/10.1182/blood-2019-130526
Published: 2019
Journal Articles

Dominant Role of αIIbβ3 in Platelet Interactions with Polymerizing Cross-Linked Fibrin

Claudia Lorena Buitrago, PhD, Barry S. Coller, MD, Hina Zafar
Journal: Blood
Blood (2019) 134 (Supplement_1): 1061.
https://doi.org/10.1182/blood-2019-122753
Published: 2019
Journal Articles

CD162 Is a Key E-Selectin Receptor Promoting Acute Myeloid Leukemia Chemo-Resistance in the Bone Marrow Niche

Johanna D Erbani, Joshua Tay, PhD, Valerie Barbier, Masters, Jean-Pierre Levesque, PhD, John L. Magnani, PhD, Ingrid G Winkler, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 907.
https://doi.org/10.1182/blood-2019-132233
Published: 2019
Journal Articles

Oxphos Inhibition Induces Formation of Tunneling Nanotubes in AML Cells and Facilitates Mitochondrial Transfer from BM Stroma to AML That Contributes to Microenvironment-Mediated Drug-Resistance of AML

Haeun Yang, Yoko Tabe, MD PhD, Kaori Saito, Kotoko Yamatani, MD, Rodrigo Jacamo, PhD, Helen Ma, MS, Vivian Ruvolo, MS, Qi Zhang, PhD, Vinitha Mary Kuruvilla, MSc, Natalia Baran, PhDMD, Junichi Imoto, Kazuho Ikeo, PhD, Kaori Moriya, Yuko Murakami-Tonami, MD PhD, Koya Suzuki, PhD, Takashi Miida, MD PhD, Michael Andreeff, MD PhD, Christopher P Vellano, Joseph Marszalek, Marina Y Konopleva, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 911.
https://doi.org/10.1182/blood-2019-125007
Published: 2019
Journal Articles

The Critical Role of Kindlin-3 in Intiation of Physiological Thrombus Formation ~ Analysis of Kindlin-3 Deficient Patient

Hisashi Kato, MD PhD, Shigenori Honda, MD, Hirokazu Kashiwagi, Nobuko Nishiura, Keigo Akuta, Koichi Kokame, Toshiyuki Miyata, Yoshiaki Tomiyama, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1062.
https://doi.org/10.1182/blood-2019-129668
Published: 2019
Journal Articles

The VLA-4 Integrin Is Constitutively Activated in a Fraction of CD49d-Expressing Chronic Lymphocytic Leukemia Via Autonomous BCR-Mediated Signaling

Erika Tissino, PhD, Tamara Bittolo, PhD, Dania Benedetti, PhD, Riccardo Bomben, PhD, Andrea Härzschel, Palash Maity, Gabriela Forestieri, Antonella Nicolò, M.Sc; B.Sc., Moumita Datta, Enrico Santinelli, MD, Francesca Maria Rossi, PhD, Alexandre Chigaev, Larry A. Sklar, Francesco Zaja, MD, Gabriele Pozzato, MD, Pietro Bulian, MD, Giovanni Francesco D'Arena, MD, Annalisa Chiarenza, MD PhD, Francesco Di Raimondo, MD, Hassan Jumaa, PhD, Davide Rossi, MD PhD, Giovanni Del Poeta, MD, Tanja Nicole Hartmann, Antonella Zucchetto, Valter Gattei, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 849.
https://doi.org/10.1182/blood-2019-124313
Published: 2019
Journal Articles

B Cell Specific Knockdown of the Erythropoietin (EPO) Receptor Attenuates EPO-Induced Bone Loss in Mice

Albert Kolomansky, MD, Naamit Deshet-Unger, PhD, Nathalie Ben-Califa, PhD, Zamzam Awida, Maria Ibrahim, B.Sc., Tamar Liron, PhD, Sahar Hiram-Bab, PhD, Howard S. Oster, MD PhD, Moshe Mittelman, MD, Martina Rauner, PhD, Ben Wielockx, PhD, Yankel Gabet, DMD, PhD, Drorit Neumann, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 939.
https://doi.org/10.1182/blood-2019-127092
Published: 2019
Journal Articles

Mature Osteoblasts Promote Multiple Myeloma Survival through Cell-Cell Contact and Immune Modulation Mechanisms

Keertik Fulzele, PhD, Cristina Panaroni, PhD, Kenta Mukaihara, MD PhD, Tomoaki Mori, MD PhD, Shrikanta Chattopadhyay, MBBS, Noopur S. Raje, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1802.
https://doi.org/10.1182/blood-2019-131213
Published: 2019
Journal Articles

Altered Structure and Function of Mesenchymal Stromal Cell-Derived Extracellular Matrix in MDS Can be Restored By Luspatercept

Manja Wobus, PhD, Anna Mies, Valentina Magno, PhD, Cindy Welzel, Susann Winter, PhD, Friedrich Stoelzel, MD, Carsten Werner, PhD, Martin Bornhaeuser, MD, Uwe Platzbecker, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1699.
https://doi.org/10.1182/blood-2019-129814
Published: 2019
Journal Articles

Alpha-Dystroglycan Supports Platelet Aggregation and Thrombus Formation

Yiming Wang, MD PhD, Reid C. Gallant, MSc, Miguel A. D. Neves, PhD MSc, Xi Lei, MSc, Sahil Gupta, MSc, Rodrigo Coelho, BSc, Tatianna Wong, MSc, Ronald D. Cohn, MD, Kevin P. Campbell, PhD, Heyu Ni, MD MSc, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 11.
https://doi.org/10.1182/blood-2019-131521
Published: 2019