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Steven D. Mittelman
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Journal Articles

Trial in Progress: Update on the TACL T2020-003 Randomized Phase 2 Trial to Improve Diet and Exercise in Acute Lymphoblastic Leukemia (IDEAL-2)

Etan Orgel, Sarah K. Tasian, Yueh-Yun Chi, Jemily Malvar, Christina M. Dieli-Conwright, Rubi Buxton, Mackenzie Frederick, Hannah Williams, Karen R Rabin, Susan R Rheingold, Robin Norris, Tamara P. Miller, Brent L. Wood, Ellynore Florendo, Ellen Chang, Lisa Hartman, Mallorie M. Heneghan, Michelle L. Hermiston, Joel Kaplan, Tamra Slone, Deepa Bhojwani, Alan S. Wayne, Steven D. Mittelman
Journal: Blood
Blood (2024) 144 (Supplement 1): 2828.1.
https://doi.org/10.1182/blood-2024-201871
Published: 2024
Journal Articles

Increased prevalence of CRLF2 rearrangements in obesity-associated acute lymphoblastic leukemia

Clinical Trials & Observations
Steven D. Mittelman, Jiyoon Kim, Gordana Raca, Gang Li, Matthew J. Oberley, Etan Orgel
Journal: Blood
Blood (2021) 138 (2): 199–202.
https://doi.org/10.1182/blood.2021011106
Published: 2021
Includes: Supplemental data
Journal Articles

Integrin α6 mediates the drug resistance of acute lymphoblastic B-cell leukemia

Eun Ji Gang, Hye Na Kim, Yao-Te Hsieh, Yongsheng Ruan, Heather A. Ogana, Solomon Lee, Jennifer Pham, Huimin Geng, Eugene Park, Lars Klemm, Cheryl L. Willman, William L. Carroll, Steven D. Mittelman, Etan Orgel, Matthew J. Oberley, Chintan Parekh, Hisham Abdel-Azim, Deepa Bhojwani, Alan S. Wayne, Adèle De Arcangelis, Elisabeth Georges-Labouesse, Elizabeth Wayner, Halvard Bonig, Aspram Minasyan, Johanna ten Hoeve, Thomas G. Graeber, Markus Müschen, Nora Heisterkamp, Yong-Mi Kim
Journal: Blood
Blood (2020) 136 (2): 210–223.
https://doi.org/10.1182/blood.2019001417
Published: 2020
Includes: Supplemental data
Journal Articles

Age but Not Adiposity Predicts Asparaginase-Induced Hepatotoxicity during Induction Therapy for Adolescent and Young Adults with Acute Lymphoblastic Leukemia

Etan Orgel, MD MS, Celia Framson, MPH, RD, Rubi Vazquez, PT DPT, David R. Freyer, DO MS, Steven D. Mittelman, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2662.
https://doi.org/10.1182/blood-2018-99-110268
Published: 2018
Journal Articles

L-Carnitine Does Not Reduce Cytotoxicity from Induction Chemotherapy for Acute Lymphoblastic Leukemia

Jessica Sea, PhD, Etan Orgel, MD MS, Steven D. Mittelman, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5156.
https://doi.org/10.1182/blood-2018-99-117921
Published: 2018
Journal Articles

Integrin alpha6-Deletion Induces Apoptosis and Src Signaling Changes in Acute Lymphoblastic Leukemia Cells

Eun Ji Gang, MD PhD, Hye Na Kim, Johanna Scott, PhD, Matthew J Oberley, MDPhD, Etan Orgel, MD MS, Steven D. Mittelman, MDPhD, Yao-Te Hsieh, PhD, Markus Muschen, MD, Deepa Bhojwani, MD, Daniel Braas, PhD, Thomas Graeber, PhD, Nora Heisterkamp, PhD, Yong-Mi Kim, MD MPH, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3878.
https://doi.org/10.1182/blood.V130.Suppl_1.3878.3878
Published: 2017
Journal Articles

Megakaryocytes Support Viability Proliferation and Protection of Primary Pre-B ALL Cells from Chemotherapy

Stephanie Nicole Shishido, PhD, EunJi Gang, MDPhD, Ruth Xu, Hye Na Kim, Yann Duchartre, PhD, Steven D. Mittelman, MDPhD, Hisham Abdel-Azim, MD, Matthew J Oberley, MDPhD, Nora Heisterkamp, PhD, Yong-Mi Kim, MDPhDMPH
Journal: Blood
Blood (2015) 126 (23): 3763.
https://doi.org/10.1182/blood.V126.23.3763.3763
Published: 2015
Journal Articles

Obesity is associated with residual leukemia following induction therapy for childhood B-precursor acute lymphoblastic leukemia

Etan Orgel, Jonathan Tucci, Waseem Alhushki, Jemily Malvar, Richard Sposto, Cecilia H. Fu, David R. Freyer, Hisham Abdel-Azim, Steven D. Mittelman
Journal: Blood
Blood (2014) 124 (26): 3932–3938.
https://doi.org/10.1182/blood-2014-08-595389
Published: 2014
Includes: Supplemental data
Journal Articles

Correlation of Body Mass Index to Dual-Energy X-Ray Absorptiometry in Assessment of Body Composition during Therapy for Childhood Acute Lymphoblastic Leukemia

Etan Orgel, MD MS, Nicole Mueske, MS, David Robert Freyer, DO, MS, Steven D Mittelman, MD PhD
Journal: Blood
Blood (2014) 124 (21): 3663.
https://doi.org/10.1182/blood.V124.21.3663.3663
Published: 2014
Journal Articles

Pituitary Iron and Volume Predicts Hypogonadal Hypogonadism in Transfusional Iron Overload

Leila Noetzli, BS, Ashok Panigrahy, MD, Steven D Mittelman, Aleya Hyderi, BS, Ani Dongelyan, BA, Thomas D. Coates, MD, John C Wood, MD, Ph.D
Journal: Blood
Blood (2011) 118 (21): 1094.
https://doi.org/10.1182/blood.V118.21.1094.1094
Published: 2011
Journal Articles

What Predicts Adrenal Insufficiency in Patients with Thalassemia Major?

Karen E Huang, MD, Steven D Mittelman, MD, PhD, Thomas D. Coates, MD, Mitchell Geffner, MD, John C Wood, MD, Ph.D
Journal: Blood
Blood (2011) 118 (21): 5299.
https://doi.org/10.1182/blood.V118.21.5299.5299
Published: 2011
Journal Articles

Pituitary Iron and Volume in Transfusional Iron Overload: Normative Data.

Leila J Noetzli, BS, Ashok Panigrahy, MD, Mehrdad Joukar, Aleya Hyderi, Steven D Mittelman, MD, PhD, Thomas Coates, John C Wood
Journal: Blood
Blood (2009) 114 (22): 4073.
https://doi.org/10.1182/blood.V114.22.4073.4073
Published: 2009
Journal Articles

Pituitary Iron and Volume in Transfusional Iron Overload.

Leila J Noetzli, Ashok Panigrahy, Mehrdad Joukar, Aleya Hyderi, Steven D Mittelman, MD, PhD, Thomas Coates, John C Wood
Journal: Blood
Blood (2009) 114 (22): 2017.
https://doi.org/10.1182/blood.V114.22.2017.2017
Published: 2009
Journal Articles

Pancreatic Iron and Pancreatic Function in Thalassemia

Leila J Noetzli, BS, Thomas D. Coates, MD, Steven D Mittelman, MD, PhD, John C Wood, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 3876.
https://doi.org/10.1182/blood.V112.11.3876.3876
Published: 2008
Journal Articles

Obesity Alters the Pharmacokinetics of Vincristine in Mice.

James W Behan, Vassilios I Avramis, PhD, Jason P Yun, Anna Butturini, MD, Steven D Mittelman, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 1636.
https://doi.org/10.1182/blood.V112.11.1636.1636
Published: 2008
Journal Articles

Adipocytes Secrete Factors That Cause Leukemia Drug Resistance.

James W Behan, Jason P Yun, Marina P Proektor, Ehsan A Ehsanipour, Anna Butturini, MD, Nora Heisterkamp, PhD, Steven D Mittelman, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 1346.
https://doi.org/10.1182/blood.V112.11.1346.1346
Published: 2008
Journal Articles

Obesity Accelerates T-Cell Leukemia in a Spontaneous Mouse Model.

Jason P Yun, Lars Klemm, James W Behan, Markus Müschen, MD, PhD, Steven D Mittelman, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 1909.
https://doi.org/10.1182/blood.V112.11.1909.1909
Published: 2008