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Michael Kühn
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Journal Articles

Acute resistance to BET inhibitors remodels compensatory transcriptional programs via p300 coactivation

Viral Shah, George Giotopoulos, Hikari Osaki, Markus Meyerhöfer, Eshwar Meduri, Aaron Gallego-Crespo, Malte Andreas Behrendt, Maria Saura-Pañella, Aarti Tarkar, Benedict Schubert, Haiyang Yun, Sarah J. Horton, Shuchi Agrawal-Singh, Dr, Patricia S Hähnel, Faisal Basheer, Dave Lugo, Ioanna Eleftheriadou, Olena Barbash, Arindam Dhar, Michael Kühn, Borhane Guezguez, Matthias Theobald, Thomas Kindler, Paolo Gallipoli, Paul Sung-Hao Yeh, Mark A. Dawson, Rab K Prinjha, Brian JP Huntly, Daniel Sasca
Journal: Blood
Blood blood.2022019306.
https://doi.org/10.1182/blood.2022019306
Published: 2024
Includes: Supplemental data
Journal Articles

The Transcriptional Activators p300/Crebbp Are Context-Dependent Functional Repressors of Interferon Genes, Offering Therapeutic Promise in AML

Markus Meyerhöfer, Viral Shah, Aarón Gallego-Crespo, Malte Andreas Behrendt, Yawen Zhou, Maria Saura-Pañella, Björn Häupl, Thomas Kindler, Matthias Theobald, Falk Butter, George S Vassiliou, Michael Kühn, Brian J P Huntly, Thomas Oellerich, Daniel Sasca
Journal: Blood
Blood (2024) 144 (Supplement 1): 152.
https://doi.org/10.1182/blood-2024-194781
Published: 2024
Journal Articles

Acute Resistance to BET Inhibitors Remodels Compensatory Transcriptional Programs Via p300 Co-Activation

Viral Shah, George Giotopoulos, Hikari Osaki, Markus Meyerhöfer, Eshwar Meduri, Aarón Gallego-Crespo, Malte Andreas Behrendt, Maria Saura-Pañella, Benedict Schubert, Haiyang Yun, Sarah J Horton, Shuchi Agrawal Singh, Patricia S Hähnel, Faisal Basheer, Dave Lugo, Michael Kühn, Borhane Guezguez, Matthias Theobald, Thomas Kindler, Paolo Gallipoli, Paul Yeh, Mark A. Dawson, Rab Prinjha, Brian J P Huntly, Daniel Sasca
Journal: Blood
Blood (2024) 144 (Supplement 1): 722.
https://doi.org/10.1182/blood-2024-202515
Published: 2024
Journal Articles

The Genomic Landscape and Its Clinical Implication in NPM1 -Mutated AML Patients: A Study within the AMLSG 09-09 Clinical Trial

Sibylle Cocciardi, Nina Weiß, Maral Saadati, Sabrina Skambraks, Daniela Weber, Isabelle Schneider, Annika Meid, Sophia Aicher, Kathrin Bengesser-Kuhn, Andrea Corbacioglu, Verena I. Gaidzik, Frauke Theis, Walter Fiedler, Michael Kühn, Ulrich Germing, Karin T. Mayer, Michael Lübbert, Felicitas Thol, Michael Heuser, Arnold Ganser, Lars Bullinger, Axel Benner, Hartmut Döhner, Konstanze Döhner
Journal: Blood
Blood (2023) 142 (Supplement 1): 4311.
https://doi.org/10.1182/blood-2023-185566
Published: 2023