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Kerstin Görlich
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Journal Articles

Single and Combinational Multiplex Base-Edited 'Universal' CAR T Cells in a Humanised Model of Primary CD7+CD33+ AML

Arnold Kloos, Christos Georgiadis, Annie Etuk, Soragia Athina Gkazi, Farhatullah Syed, Toni Braybrook, Hong Zhan, Renuka Kadirkamanathan, Nadine Kattre, Kerstin Görlich, Thomas Fangmann, Axel Schambach, Martin G. Sauer, Michael Heuser, Waseem Qasim
Journal: Blood
Blood (2022) 140 (Supplement 1): 7425–7426.
https://doi.org/10.1182/blood-2022-168719
Published: 2022
Journal Articles

Efficacy of Chemotherapy, Phd-Inhibitor Molidustat or BRD4 Inhibitor JQ1 in Combination with Targeted Inhibition of Mutated IDH1 in Human AML In Vivo

Anuhar Chaturvedi, PhD, Charu Gupta, Stefan Kaulfuss, PhD, Basem Othman, Kerstin Görlich, Renate Schottmann, Olaf Panknin, Markus Wagner, PhD, Arnold Ganser, MD, Michael Jeffers, PhD, Andrea Haegebarth, Michael Heuser, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3933.
https://doi.org/10.1182/blood-2019-124016
Published: 2019
Journal Articles

Signaling Pathways of Mutant IDH1 Independent of R-2-Hydroxyglutarate

Charu Gupta, Michelle Maria Araujo Cruz, PhD, Nidhi Jyotsana, PhD, Amit Sharma, PhD, Ramya Goparaju, PhD, Kerstin Görlich, Renate Schottmann, Eduard Struys, PhD, Erwin E Jansen, Felicitas Thol, MD, Arnold Ganser, MD, Michael Heuser, MD, Anuhar Chaturvedi, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2617.
https://doi.org/10.1182/blood-2018-99-110159
Published: 2018
Journal Articles

Prolyl Hydroxylase 3 (Phd3) Is a Therapeutic Target in Isocitrate Dehydrogenase 1 (IDH1) Mutated Acute Myeloid Leukemia

Anuhar Chaturvedi, PhD, Michelle Maria Araujo Cruz, PhD, Ramya Goparaju, PhD, Razif Gabdoulline, Renate Schottmann, Kerstin Görlich, Arnold Kloos, Felicitas Thol, MD, Robert Geffers, PhD, Dimitrios Mougiakakos, Peter Carmeliet, MD PhD, Arnold Ganser, MD, Michael Heuser, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 759.
https://doi.org/10.1182/blood-2018-99-110425
Published: 2018
Journal Articles

Synergistic Activity of IDH1 Inhibitor Bay-1436032 with Azacitidine in IDH1 Mutant Acute Myeloid Leukemia

Anuhar Chaturvedi, PhD, Charu Gupta, Ramya Goparaju, Razif Gabdoulline, PhD, Stefan Kaulfuss, PhD, Kerstin Görlich, Renate Schottmann, Olaf Panknin, Markus Wagner, PhD, Robert Geffers, PhD, Arnold Ganser, MD, Felicitas Thol, MD, Michael Jeffers, PhD, Andrea Haegebarth, Michael Heuser, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1352.
https://doi.org/10.1182/blood.V130.Suppl_1.1352.1352
Published: 2017
Journal Articles

High-Throughput Drug Screening Identifies Pyrimethamine As a Potent and Selective Inhibitor of Acute Myeloid Leukemia

Amit Sharma, PhD, Nidhi Jyotsana, Courteney K. Lai, BSc, Anuhar Chaturvedi, PhD, Kerstin Görlich, Cecilia Murphy, Jan E. Blanchard, Arnold Ganser, Eric Brown, John A. Hassell, R. Keith Humphries, MD PhD, Michael A Morgan, PhD, Michael Heuser, MD
Journal: Blood
Blood (2014) 124 (21): 2304.
https://doi.org/10.1182/blood.V124.21.2304.2304
Published: 2014
Journal Articles

Mutant IDH1 promotes leukemogenesis in vivo and can be specifically targeted in human AML

Anuhar Chaturvedi, Michelle Maria Araujo Cruz, Nidhi Jyotsana, Amit Sharma, Haiyang Yun, Kerstin Görlich, Martin Wichmann, Adrian Schwarzer, Matthias Preller, Felicitas Thol, Johann Meyer, Reinhard Haemmerle, Eduard A. Struys, Erwin E. Jansen, Ute Modlich, Zhixiong Li, Laura M. Sly, Robert Geffers, Robert Lindner, Dietmar J. Manstein, Ulrich Lehmann, Jürgen Krauter, Arnold Ganser, Michael Heuser
Journal: Blood
Blood (2013) 122 (16): 2877–2887.
https://doi.org/10.1182/blood-2013-03-491571
Published: 2013
Includes: Supplemental data
Journal Articles

Frequency and prognostic impact of mutations in SRSF2 , U2AF1 , and ZRSR2 in patients with myelodysplastic syndromes

Felicitas Thol, Sofia Kade, Carola Schlarmann, Patrick Löffeld, Michael Morgan, Jürgen Krauter, Marcin W. Wlodarski, Britta Kölking, Martin Wichmann, Kerstin Görlich, Gudrun Göhring, Gesine Bug, Oliver Ottmann, Charlotte M. Niemeyer, Wolf-Karsten Hofmann, Brigitte Schlegelberger, Arnold Ganser, Michael Heuser
Journal: Blood
Blood (2012) 119 (15): 3578–3584.
https://doi.org/10.1182/blood-2011-12-399337
Published: 2012
Includes: Supplemental data
Journal Articles

Integrative prognostic risk score in acute myeloid leukemia with normal karyotype

Clinical Trials & Observations
Frederik Damm, Michael Heuser, Michael Morgan, Katharina Wagner, Kerstin Görlich, Anika Großhennig, Iyas Hamwi, Felicitas Thol, Ewa Surdziel, Walter Fiedler, Michael Lübbert, Lothar Kanz, Christoph Reuter, Gerhard Heil, Ruud Delwel, Bob Löwenberg, Peter J. M. Valk, Jürgen Krauter, Arnold Ganser
Journal: Blood
Blood (2011) 117 (17): 4561–4568.
https://doi.org/10.1182/blood-2010-08-303479
Published: 2011
Includes: Supplemental data