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José Angel Martínez-Climent
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Journal Articles

The alternative RelB NF-κB subunit is a novel critical player in diffuse large B-cell lymphoma

Baptiste Eluard, Stéphanie Nuan-Aliman, Nathalie Faumont, Davi Collares, Didier Bordereaux, Aurélie Montagne, Isabelle Martins, Nicolas Cagnard, Martial Caly, Oussama Taoui, Leonardo Lordello, Jacqueline Lehmann-Che, Bruno Tesson, Jose-Angel Martinez-Climent, Christiane Copie-Bergman, Corinne Haioun, Hervé Tilly, Benjamin Bonsang, Anne Vincent-Salomon, Jean-Philippe Jais, Fabrice Jardin, Karen Leroy, Maria Chiara Maiuri, Guido Kroemer, Thierry Jo Molina, Jean Feuillard, Véronique Baud
Journal: Blood
Blood (2022) 139 (3): 384–398.
https://doi.org/10.1182/blood.2020010039
Published: 2022
Includes: Supplemental data
Journal Articles

Deep MRD profiling defines outcome and unveils different modes of treatment resistance in standard- and high-risk myeloma

Clinical Trials & Observations
Ibai Goicoechea, Noemi Puig, Maria-Teresa Cedena, Leire Burgos, Lourdes Cordón, María-Belén Vidriales, Juan Flores-Montero, Norma C. Gutierrez, Maria-Jose Calasanz, Maria-Luisa Martin Ramos, David Lara-Astiaso, Amaia Vilas-Zornoza, Diego Alignani, Idoia Rodriguez, Sarai Sarvide, Daniel Alameda, Juan José Garcés, Sara Rodriguez, Vicente Fresquet, Jon Celay, Ramón Garcia-Sanz, Joaquin Martinez-Lopez, Albert Oriol, Rafael Rios, Jesus Martin-Sanchez, Rafael Martinez-Martinez, Josep Sarra, Miguel-Teodoro Hernandez, Javier de la Rubia, Isabel Krsnik, Jose-Maria Moraleda, Luis Palomera, Joan Bargay, Jose-Angel Martinez-Climent, Alberto Orfao, Laura Rosiñol, Maria-Victoria Mateos, Juan-José Lahuerta, Joan Blade, Jesús San Miguel, Bruno Paiva
Journal: Blood
Blood (2021) 137 (1): 49–60.
https://doi.org/10.1182/blood.2020006731
Published: 2021
Includes: Supplemental data
Journal Articles

Waldenström's Macroglobulinemia (WM) Is Preceded By Clonal Lymphopoiesis Including MYD88 L265P in Progenitor B Cells

Sara Rodríguez, PhD, Cirino Botta, MDPhD, Jon Celay, PhD, Ibai Goicoechea, PhD, Cristina Jiménez, PhD, Maria J Garcia-Barchino, PhD, Rafael Valdés-Mas, Yolanda Carrasco, Juan José Garcés, Marta Larrayoz, PhD, Susana Santos, Diego Alignani, PhD, Amaia Vilas-Zornoza, PhD, Cristina Pérez Ruiz, Sonia Garate, Sarvide Sarai, Aitziber Lopez Lopez, Christian Reinhardt, MD, Isidro Sanchez-Garcia, PhD, Maria Jose Larrayoz, BSc, María José Calasanz, PhD, Felipe Prosper, MD, Marina Motta, MD, Giuseppe Rossi, MD, Antonio Sacco, RN, Massimo Gentile, Sara Duarte, Helena Vitoria, Catarina Geraldes, MD PhD, Artur Paiva, Ramón Garcia-Sanz, MD PhD, Aldo M. Roccaro, MDPhD, Jesus F. San-Miguel, MD PhD, Jose Angel Martinez-Climent, MD PhD, Bruno Paiva, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 42–43.
https://doi.org/10.1182/blood-2020-136982
Published: 2020
Journal Articles

Discordances between Immunofixation (IFx) and Minimal Residual Disease (MRD) Assessment with Next-Generation Flow (NGF) and Sequencing (NGS) in Patients (Pts) with Multiple Myeloma (MM): Clinical and Pathogenic Significance

Sara Rodríguez, PhD, Ibai Goicoechea, PhD, Katerina Gemenetzi, Cirino Botta, MDPhD, Andreas Agathangelidis, PhD, Noemi Puig, MD PhD, María Teresa Cedena, MD, Alejandro Medina, MD, Rafael Valdés-Mas, Juan José Garcés, José J Pérez, Leire Burgos, María José Calasanz, PhD, Diego Alignani, PhD, Amaia Vilas-Zornoza, PhD, Sarvide Sarai, Felipe Prosper, MD, Jose Angel Martinez-Climent, MD PhD, Alberto Orfao, MD PhD, Ramón García-Sanz, MD PhD, Ana Jiménez Ubieto, MDPhD, Joaquin Martinez Lopez, Juan Jose Lahuerta, MD PhD, Laura Rosinol, MD PhD, Joan Bladé, MD PhD, María-Victoria Mateos, MD PhD, Anastasia Chatzidimitriou, Jesus F. San-Miguel, MD PhD, Bruno Paiva, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 5–6.
https://doi.org/10.1182/blood-2020-136258
Published: 2020
Journal Articles

The Pathogenesis of Multiple Myeloma (MM) Is Preceded By Mutated Lymphopoiesis and B Cell Oligoclonality That Persist in Patients with Negative Minimal Residual Disease (MRD)

Sara Rodríguez, PhD, Noemi Puig, MD PhD, Katerina Gemenetzi, Ibai Goicoechea, PhD, Cirino Botta, MD, Andreas Agathangelidis, PhD, Rafael Valdés-Mas, Juan José Garcés, María Teresa Cedena, José J Pérez, Leire Burgos, Maria Jose Calasanz, PhD BSc, Diego Alignani, PhD, Amaia Vilas-Zornoza, PhD, Erika Lorenzo-Vivas, PhD, Irene Aires, Idoia Rodriguez, Sarvide Sarai, Felipe Prosper, MD PhD, Jose Angel Martinez-Climent, MD PhD, Alberto Orfao, MD PhD, Ramón García-Sanz, MD PhD, Joaquin Martinez-Lopez, MD PhD, Juan-José Lahuerta, MD PhD, Laura Rosinol Dachs, Joan Bladé, MD, Maria-Victoria Mateos, Anastasia Hadzidimitriou, PhD, Jesús San-Miguel, Bruno Paiva, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 509.
https://doi.org/10.1182/blood-2019-128049
Published: 2019
Journal Articles

Waldenström's Macroglobulinemia (WM) Is Preceded By Clonal Lymphopoiesis Including MYD88 L265P in Progenitor B Cells

Sara Rodríguez, PhD, Cirino Botta, MD, Jon Celay, PhD, Ibai Goicoechea, PhD, Maria J Garcia-Barchino, PhD, Rafael Valdés-Mas, Yolanda Carrasco, Daniel Alameda, PhD, Juan José Garcés, Marta Larrayoz, PhD, Susana Santos, Diego Alignani, PhD, Amaia Vilas-Zornoza, PhD, Erika Lorenzo-Vivas, PhD, Cristina Pérez Ruiz, Sonia Garate, Sarvide Sarai, Amaia Gascue, Christian Reinhardt, MD, Isidro Sanchez-Garcia, PhD, Maria Jose Larrayoz, PhD, Maria Jose Calasanz, PhD BSc, Felipe Prosper, MD PhD, Marina Motta, Antonella Anastasia, Antonio Sacco, RN, Massimo Gentile, Sara Duarte, Helena Vitoria, Catarina Geraldes, MD PhD, Artur Paiva, Aldo M. Roccaro, MD PhD, Jesús San-Miguel, Jose Angel Martinez-Climent, MD PhD, Bruno Paiva, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1527.
https://doi.org/10.1182/blood-2019-126889
Published: 2019
Journal Articles

PD-1/PD-L1 immune checkpoint and p53 loss facilitate tumor progression in activated B-cell diffuse large B-cell lymphomas

Marién Pascual, María Mena-Varas, Eloy Francisco Robles, Maria-Jose Garcia-Barchino, Carlos Panizo, Sandra Hervas-Stubbs, Diego Alignani, Ainara Sagardoy, Jose Ignacio Martinez-Ferrandis, Karen L. Bunting, Stephen Meier, Xavier Sagaert, Davide Bagnara, Elizabeth Guruceaga, Oscar Blanco, Jon Celay, Alvaro Martínez-Baztan, Noelia Casares, Juan José Lasarte, Thomas MacCarthy, Ari Melnick, Jose Angel Martinez-Climent, Sergio Roa
Journal: Blood
Blood (2019) 133 (22): 2401–2412.
https://doi.org/10.1182/blood.2018889931
Published: 2019
Includes: Supplemental data
Journal Articles

Induced Transdifferentiation of Leukemia B-Cells to Macrophages Involves Reconfiguration of the DNA Methylome

Alberto Bueno-Costa, David Piñeyro, Marta Soler, Biola Maria Javierre, José Angel Martínez-Climent, Manel Esteller, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5115.
https://doi.org/10.1182/blood-2018-99-111580
Published: 2018
Journal Articles

NIK and the Alternative NF-κB Pathway in Human Lymphomas.

Lina Odqvist, Margarita Sanchez-Beato, Santiago Montes-Moreno, Cristina Gomez-Abad, Lydia Sanchez, Ana Rodriguez-Lopez, Jose Angel Martinez-Climent, Joaquin Martinez-Lopez, Francisco Javier Alves, Miguel A. Piris, MD
Journal: Blood
Blood (2009) 114 (22): 3943.
https://doi.org/10.1182/blood.V114.22.3943.3943
Published: 2009
Journal Articles

Identification and Characterization of Single Nucleotide Polymorphisms (SNPs) Associated with Genetic Predisposition to Develop Therapy-Related Acute Myeloid Leukemia (t-AML).

Vicent M. Guillem, PhD, Mar Tormo, MD, Jose Angel Martinez-Climent, MD, Ana Lluch, MD, Isabel Benet, MD, Marcos Gonzalez, MD, Josep Nomdedeu, MD, Javier Garcia-Conde, MD
Journal: Blood
Blood (2004) 104 (11): 3001.
https://doi.org/10.1182/blood.V104.11.3001.3001
Published: 2004
Journal Articles

MALT1 is deregulated by both chromosomal translocation and amplification in B-cell non-Hodgkin lymphoma

Dolors Sanchez-Izquierdo, Gerard Buchonnet, Reiner Siebert, Randy D. Gascoyne, Joan Climent, Loraine Karran, Miguel Marin, David Blesa, Douglas Horsman, Andreas Rosenwald, Louis M. Staudt, Donna G. Albertson, Ming-Qing Du, Hongtao Ye, Peter Marynen, Javier Garcia-Conde, Daniel Pinkel, Martin J. S. Dyer, Jose Angel Martinez-Climent
Journal: Blood
Blood (2003) 101 (11): 4539–4546.
https://doi.org/10.1182/blood-2002-10-3236
Published: 2003
Includes: Supplemental data