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Journal Articles

Deep MRD profiling defines outcome and unveils different modes of treatment resistance in standard- and high-risk myeloma

Clinical Trials & Observations
Ibai Goicoechea, Noemi Puig, Maria-Teresa Cedena, Leire Burgos, Lourdes Cordón, María-Belén Vidriales, Juan Flores-Montero, Norma C. Gutierrez, Maria-Jose Calasanz, Maria-Luisa Martin Ramos, David Lara-Astiaso, Amaia Vilas-Zornoza, Diego Alignani, Idoia Rodriguez, Sarai Sarvide, Daniel Alameda, Juan José Garcés, Sara Rodriguez, Vicente Fresquet, Jon Celay, Ramón Garcia-Sanz, Joaquin Martinez-Lopez, Albert Oriol, Rafael Rios, Jesus Martin-Sanchez, Rafael Martinez-Martinez, Josep Sarra, Miguel-Teodoro Hernandez, Javier de la Rubia, Isabel Krsnik, Jose-Maria Moraleda, Luis Palomera, Joan Bargay, Jose-Angel Martinez-Climent, Alberto Orfao, Laura Rosiñol, Maria-Victoria Mateos, Juan-José Lahuerta, Joan Blade, Jesús San Miguel, Bruno Paiva
Journal: Blood
Blood (2021) 137 (1): 49–60.
https://doi.org/10.1182/blood.2020006731
Published: 2021
Includes: Supplemental data
Journal Articles

Clinical Significance and Transcriptional Profiling of Persistent Minimal Residual Disease (MRD) in Multiple Myeloma (MM) Patients with Standard-Risk (SR) and High-Risk (HR) Cytogenetics

Ibai Goicoechea, PhD, Noemi Puig, MD PhD, María Teresa Cedena, Lourdes Cordon, Maria-Belen Vidriales, MD, Leire Burgos, Juan Flores-Montero, Norma C. Gutierrez, MD PhD, Maria Jose Calasanz, BSc, PhD, Maria Luisa Martin-Ramos, David Lara-Astiaso, PhD, Amaia Vilas-Zornoza, PhD, Diego Alignani, PhD, Idoia Rodriguez, Sarai Sarvide, Ramon Garcia-Sanz, MD PhD, Joaquin Martinez-Lopez, MD PhD, Albert Oriol, MD, Rafael Rios, MD PhD, Jesús Martín, Rafael Martínez, Josep Sarra, Miguel T Hernández, MD PhD, Javier De La Rubia, MD, Isabel Krsnik, Jose Maria Moraleda, Luis Palomera, MD PhD, Joan Bargay, MD PhD, Alberto Orfao, MD PhD, Laura Rosiñol, Maria-Victoria Mateos, MD PhD, Juan Jose Lahuerta, MD PhD, Joan Bladé, MD PhD, Jesus F San-Miguel, MD PhD, Bruno Paiva, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 112.
https://doi.org/10.1182/blood-2018-99-113312
Published: 2018
Journal Articles

Immunofixation (IF) in Urine Is Really Necessary to Define Complete Remission in Multiple Myeloma (MM)? a Subanalysis from the Pethema/GEM2012MENOS65 Phase III Clinical Trial

Ana Jiménez Ubieto, MD PhD, Bruno Paiva, MD PhD, Joaquin Martínez-López, MD PhD, Laura Rosinol, MD PhD, Maria Teresa Cedena Romero, MD PhD, Maria Jose Calasanz, BSc, PhD, Noemi Puig, MD PhD, Ramon Garcia-Sanz, MD PhD, Norma C. Gutierrez, MD PhD, Maria Luisa Martin-Ramos, Albert Oriol, MD, José Gonzalez Medina, Rafael Alonso Fernandez, Jesús Blanchard, MD, Rafael Rios, MD PhD, Jesús Martín, Rafael Martinez Martinez, Josep Sarra, Miguel-Teodoro Hernández, Javier De La Rubia, MD, Isabel Krsnik, MD PhD, Jose Maria Moraleda, Luis Palomera, MD PhD, Maria-Victoria Mateos, MD PhD, Jesús F San-Miguel, MD, Joan Bladé, MD, Juan-José Lahuerta, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 474.
https://doi.org/10.1182/blood-2018-99-115050
Published: 2018
Journal Articles

Impact of Next-Generation Flow (NGF) Minimal Residual Disease (MRD) Monitoring in Multiple Myeloma (MM): Results from the Pethema/GEM2012 Trial

Bruno Paiva, PhD, Noemi Puig, MD PhD, Maria Teresa Cedena, Lourdes Cordon, Maria-Belen Vidriales, Leire Burgos, Juan Flores-Montero, Lucía Lopez-Anglada, Norma Gutierrez, MD PhD, Maria Jose Calasanz, BSc, PhD, Maria Luisa Martin-Ramos, Ramon Garcia-Sanz, MD PhD, Joaquin Martinez-Lopez, MD PhD, Albert Oriol, MD, M Jesús Blanchard, Rafael Rios, Jesús Martín, Rafael Martínez, Josep Sarra, Miguel T Hernández, Javier de la Rubia, Isabel Krsnik, Jose M Moraleda, Luis Palomera, Juan Bargay, Alberto Orfao, MD PhD, Laura Rosinol, MD PhD, Maria-Victoria Mateos, MD, Juan-José Lahuerta, Joan Bladé, MD PhD, Jesus F. San Miguel, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 905.
https://doi.org/10.1182/blood.V130.Suppl_1.905.905
Published: 2017
Journal Articles

Renal Response in Patients (Pts) with Relapsed Refractory Multiple Myeloma (RRMM): Interim Data of a Large Observational, Prospective Study

Javier de la Rubia, Enrique Morales, Fernando Escalante, Mª Soledad Durán, Manuel Perez Encinas, Merche Gironella, Tomas J Gonzalez-Lopez, Ignacio Español, Josep Sarrà, Elena Cabezudo, Esther Gonzalez, Carmen Calle, Rafael Martinez, Mario Arnao, Yolanda González, MD, José Antonio Márquez, Valentin Cabañas, Joan Blade, Antonio Ruiz Boza, Antonio Garcia
Journal: Blood
Blood (2014) 124 (21): 2104.
https://doi.org/10.1182/blood.V124.21.2104.2104
Published: 2014
Journal Articles

Phase 2 Study Of Bendamustine, Bortezomib (Velcade) and Prednisone (BVP) For Newly Diagnosed Multiple Myeloma (MM)

Maria-Victoria Mateos, MD, Ph.D, Albert Oriol, MD, Laura Rosiñol, MD, Felipe de Arriba, Jesús Martín, Joaquín Martínez-López, MD, PhD, Maria Asuncion Echeveste, Josep Sarrá, MD, Gemma Ramirez, Enrique M. Ocio, Rafael Martinez, MD, Luis Palomera, MD, Angel Payer, Rebeca Iglesias, Javier De La Rubia, MD, PhD, Adrian Alegre, MD, Anabelle Chinea, Joan Bladé, MD, PhD, Juan José Lahuerta, Jesús F San Miguel, MD
Journal: Blood
Blood (2013) 122 (21): 2155.
https://doi.org/10.1182/blood.V122.21.2155.2155
Published: 2013
Journal Articles

Prognostic Significance Of Copy Number Alterations In B-Lineage Adult Acute Lymphoblastic Leukemia Patients Enrolled In Risk-Adapted Protocols From The Pethema Group

Jordi Ribera, Lurdes Zamora, PhD, Mireia Morgades, Ramon Guardia, MD, Josep Sarrá, MD, Inés Gómez-Seguí, MD., Pau Montesinos, Marta Pratcorona, Jordi Esteve, MD, PhD, Josep F. Nomdedeu, MD, Salut Brunet, MD, Mar Tormo, MD, Maria Collado, Joaquín Martínez, Pilar Martinez-Sanchez, MD, Jesus Maria Hernández-Rivas, MD, Marcos González, MD, José González-Campos, MD, Pablo Trujillo, Pere Barba, MD, Neus Ruiz-Xivillé, Isabel Granada, Silvia Marce, PhD, Marta Cabezón, Eulàlia Genescà, PhD, Francesc Solé, PhD, Jordi Juncà, MD, Fuensanta Millá, MD, PhD, Evarist Feliu, MD, PhD, Josep-Maria Ribera, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2556.
https://doi.org/10.1182/blood.V122.21.2556.2556
Published: 2013
Journal Articles

Different Prognosis According to Subtype-Oriented Protocols in Elderly Patients with Acute Lymphoblastic Leukemia (ALL). Comparison of Three Prospective Parallel Trials from the Pethema Group

Josep-Maria Ribera, MD, PhD, Olga Garcia, Pascual Fernandez, Pau Montesinos, Salut Brunet, Maria del Pilar Martinez, Esperanza Lavilla, Teresa Bernal, MD, Jose González, MD, PhD, Mar Tormo, MD, Pere Barba, Carmen Monteserín, Josep Sarrá, MD, Marta Fernandez, Mercedes Colorado, Andrés Novo, Antonio Garcia, Maria Calbacho, Eugenia Abella, Maria-Jose Moreno, Jesús-Maria Hernández-Rivas, MD, PhD, Maria-Elsa Lopez, Natalia Alonso, Alfons Serrano, Evarist Feliu, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 3869.
https://doi.org/10.1182/blood.V122.21.3869.3869
Published: 2013
Journal Articles

Validation Of a Comprehensive Health Status Assessment Scale In Older Patients (≥ 65 years) With Hematological Malignances. Gah Study

Santiago Bonanad, MD, Ernesto Perez Persona, MD, Itziar Oiartzabal, MD, Bernardo Gonzalez, Carlos Fernandez-Lago, MD, Maria Teresa Zudaire, MD, Mercedes Gironella, MD, Alfonso Soler, MD, David Valcarcel, MD, Jose Ángel Hernández-Rivas, MD, Carmen Marrero, MD, Montserrat Arnan, MD, Carmen Olivier, MD, Pau Abrisqueta, MD, Blanca Xicoy, MD, PhD, Josep Sarrá, MD, Benet Nomdedeu, MD, PhD, Eva González, MD, Jesus Martinez, MD, José González-Campos, MD, Cristina Encinas, MD, Almudena Laiglesia, MD, Cristina Fernández-Maqueda, MD, Isidro Jarque, MD, Christelle Ferra, MD, José Falantes, MD, Estrella Carrillo, MD, Cristina Muñoz, MD, J Feliú, MD, Marta Durán, Marina Marcos, Silvia López, Alfonso J Cruz-Jentoft, MD, PhD, Javier De La Rubia, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2979.
https://doi.org/10.1182/blood.V122.21.2979.2979
Published: 2013
Journal Articles

Treatment of Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma (ALL/LL). Results of a Single Center.

Josep Sarra, Esmeralda de la Banda, MD, Encuentra Maite, Jose Petit, Eva Gonzalez-Barca, Eva Domingo-Domènech, MD, Ana Carla Oliveira, Santiago Mercadal, MD, Victoria Clapes, Alberto Fernandez de Sevilla, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 4108.
https://doi.org/10.1182/blood.V114.22.4108.4108
Published: 2009
Journal Articles

Treatment of High-Risk (HR) Philadelphia Chromosome-Negative (Ph-) Adult Acute Lymphoblastic Leukemia (ALL) According to Baseline Risk Factors and Minimal Residual Disease (MRD). Results of the PETHEMA ALL-AR-03 Trial Including the Use of Propensity Score (PS) Method to Reduce Assignment Bias.

Josep-Maria Ribera, Albert Oriol, Mireia Morgades, Miguel-Angel Sanz, Pau Montesinos, Josep Sarra, Salut Brunet, Pascual Fernández-Abellan, Ramon Guardia, Jordi Esteve, Jose Gonzalez-Campos, Arancha Bermudez, Maria-Jose Moreno, Maria-Teresa Bernal, Mar Tormo, Eloy Del Potro, Antonia Cladera, Andreu Llorente, Raimundo Garcia-Boyero, Maria-Jose Rabuñal, Juan Bergua, Carlos Grande, Maria-Luz Amigo, Javier Bueno, Concepcion Bethencourt, Jesus-Maria Hernandez-Rivas, Evarist Feliu
Journal: Blood
Blood (2009) 114 (22): 322.
https://doi.org/10.1182/blood.V114.22.322.322
Published: 2009
Journal Articles

Treatment of High-Risk (HR) Philadelphia Chromosome-Negative (Ph-) Adult Acute Lymphoblastic Leukemia (ALL) According to Baseline Risk Factors and Minimal Residual Disease (MRD). Results of the PETHEMA ALL-AR-03 Trial.

Josep-Maria Ribera, Albert Oriol, Mireia Morgades, Josep Sarra, Pau Montesinos, Salut Brunet, Ramon Guardia, Pascual Fernández-Abellan, Teresa Bernal, MD, Arancha Bermudez, Maria-Jose Moreno, Ricardo Parody, Mar Tormo, Eloy Del Potro, Andreu Llorente, Raimundo Garcia-Boyero, Jordi Esteve, Maria-Jose Rabuñal, Emilia Pardal, Carlos Grande, Javier Bueno, Antonia Cladera, Concepcion Bethencourt, Victoria Martin-Reina, Maria-Luz Amigo, Jesus-Maria Hernandez-Rivas, Miguel-Angel Sanz, Evarist Feliu
Journal: Blood
Blood (2008) 112 (11): 3291.
https://doi.org/10.1182/blood.V112.11.3291.3291
Published: 2008