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Journal Articles

Associations between serum asparaginase activity and asparaginase-associated toxicities in pediatric ALL patients receiving calaspargase: A report from the DFCI ALL consortium

Free
Sara Mohamed, Yael Flamand, Victoria Koch, Lynda Vrooman, Peter Cole, Lisa Gennarini, Kara Kelly, Bruno Michon, Thai Hoa Tran, Jennifer Welch, Jeffrey Supko, Justine Kahn, Lewis Silverman
Journal: Blood
Blood (2025) 146 (Supplement 1): 5104.
https://doi.org/10.1182/blood-2025-5104
Published: 2025
Journal Articles

Safety and effectiveness of standard versus extended duration of anticoagulation in children with acute lymphoblastic leukemia and venous thrombo-embolism

Free
Marie-Claude Pelland-Marcotte, Thai Hoa Tran, Chantal Éthier, Camille Beaulieu, Thien-Vu Truong, Olivia Perrone, Nadia Tarhini, Juliann Duzan, Lynda Vrooman, Melissa Burns, Lewis Silverman, Riten Kumar
Journal: Blood
Blood (2025) 146 (Supplement 1): 3123.
https://doi.org/10.1182/blood-2025-3123
Published: 2025
Journal Articles

Clinical characteristics and outcomes of children with T-cell acute lymphoblastic leukemia harboring ABL-class fusions: A report from the ponte di legno consortium

Free
Thai Hoa Tran, Meenakshi Devidas, Leyna Xoi, Andishe Attarbaschi, Judith Boer, Gunnar Cario, Giovanni Cazzaniga, Gabriele Escherich, Yoshihiro Gocho, Mats Heyman, Stephen Hunger, Hiroto Inaba, Gabor Kovacs, Anthony Moorman, Charles Mullighan, Kjeld Schmiegelow, Jan Stary, Tomasz Szczepanski, David Teachey, Andrea Biondi, Mignon Loh, Rob Pieters, Sarah Elitzur
Journal: Blood
Blood (2025) 146 (Supplement 1): 761.
https://doi.org/10.1182/blood-2025-761
Published: 2025
Journal Articles

The prolong trial: A two Phase randomized placebo-controlled trial to optimize rituximab response with dexamethasone and maintenance therapy with low dose rituximab in immune thrombocytopenia (ITP) patients

Free
Waleed Ghanima, Doaa El Demerdash, Henrik Frederiksen, James Bussel, Galina Tsykunova, Marc Michel, Hoa Tran, Carina Nassar, Bernadette Darne, Eirik Tjønnfjord, Tor Henrik Tvedt, Fehmi M'Sadek, Mervat Mattar, Abderraheem Khelif, Pål Holme
Journal: Blood
Blood (2025) 146 (Supplement 1): 736.
https://doi.org/10.1182/blood-2025-736
Published: 2025
Journal Articles

Comprehensive and rapid detection of genomic alterations in pediatric leukemias using whole-genome sequencing with adaptive sampling

Free
Nicholas Geoffrion, Charlene Lawruk-Desjardins, Sylvie Langlois, Marjorie Aleman Alvarado, Niklas Dreyer, Anthony Carrier, Véronique Lisi, Chantal Richer, Alex Saint-Hilaire, Pascal Tremblay-Dauphinais, Banafsheh Khakipoor, Sandy Fong, Adam Shlien, Sonia Cellot, Thai Hoa Tran, Daniel Sinnett, Vincent-Philippe Lavallee
Journal: Blood
Blood (2025) 146 (Supplement 1): 4337.
https://doi.org/10.1182/blood-2025-4337
Published: 2025
Journal Articles

The holistic trial: A comprehensive evaluation of two second-line therapeutic approaches for immune thrombocytopenia (ITP) – a pragmatic randomized controlled trial

Free
Eirik Tjønnfjord, Inge Christoffer Olsen, Lamya Garabet, Hoa Tran, Doaa El Demerdash, Salam AlKindy, Geir Tjønnfjord, Waleed Ghanima
Journal: Blood
Blood (2025) 146 (Supplement 1): 8226.
https://doi.org/10.1182/blood-2025-8226
Published: 2025
Journal Articles

Fixed-duration versus continuous targeted treatment for previously untreated chronic lymphocytic leukemia: Results from the randomized CLL17 trial

Free
Othman Al-Sawaf, Janina Stumpf, Can Zhang, Florian Simon, Francesc Bosch Albareda, Emadoldin Feyzi, Paolo Ghia, Michael Gregor, Arnon Kater, Vesa Lindström, Mattias Mattsson, Carsten Niemann, Philipp Staber, Tamar Tadmor, Patrick Thornton, Clemens-Martin Wendtner, Ann Janssens, Thomas Noesslinger, Jan-Paul Bohn, Caspar da Cunha-Bang, Christian Poulsen, Juha Ranti, Thomas Illmer, Bjoern Schoettker, Sebastian Böttcher, Tobias Gaska, Elisabeth Vandenberghe, Ruth Clifford, Ohad Benjamini, Annamaria Frustaci, Lydia Scarfo, Paolo Sportoletti, John Schreurs, Mark-David Levin, Hanneke van der Straaten, Marjolein van der Klift, Hoa Tran, Javier de la Serna, Javier Loscertales, Oscar Lindblad, Anna Bergendahl Sandstedt, Jeroen Goede, Michael Baumann, Anna Maria Fink, Kirsten Fischer, Matthias Ritgen, Karl-Anton Kreuzer, Christof Schneider, Eugen Tausch, Stephan Stilgenbauer, Sandra Robrecht, Barbara Eichhorst, Michael Hallek
Journal: Blood
Blood (2025) 146 (Supplement 1): 1.
https://doi.org/10.1182/blood-2025-1
Published: 2025
Journal Articles

Comparison of paired bone marrow and peripheral blood measurable residual disease in pediatric acute lymphoblastic leukemia by next-generation sequencing: A report from the dana farber ALL consortium protocol 16-001.

Free
Jennifer Welch, Yael Flamand, Victoria Koch, Peter Cole, Lisa Gennarini, Justine Kahn, Kara Kelly, Bruno Michon, Thai Hoa Tran, Ilan Kirsch, Heidi Simmons, Melissa Burns, Lewis Silverman, Marian Harris
Journal: Blood
Blood (2025) 146 (Supplement 1): 5146.
https://doi.org/10.1182/blood-2025-5146
Published: 2025
Journal Articles

How I treat Philadelphia chromosome–like acute lymphoblastic leukemia in children, adolescents, and young adults

Available to Purchase
Thai Hoa Tran, Sarah K. Tasian
Journal: Blood
Blood (2025) 145 (1): 20–34.
https://doi.org/10.1182/blood.2023023153
Published: 2025
Journal Articles

Household Material Hardship and Inpatient Days in Dana-Farber Cancer Institute (DFCI) Acute Lymphoblastic Leukemia (ALL) Consortium Trial 16-001

Free
Kristine A Karvonen, Morgan A. Paul, Yael Flamand, Puja J. Umaretiya, Rahela Aziz-Bose, Colleen A. Kelly, Leanne Duhaney, Daniel J. Zheng, Lucille Lokko, Victoria Koch, Peter D. Cole, Lisa M. Gennarini, Justine M. Kahn, Kara M. Kelly, Thai Hoa Tran, Bruno Michon, Jennifer J.G. Welch, Joanne Wolfe, Lewis B. Silverman, Kira Bona
Journal: Blood
Blood (2024) 144 (Supplement 1): 3649.
https://doi.org/10.1182/blood-2024-199274
Published: 2024
Journal Articles

Public Insurance As a Proxy Measure of Household Poverty-Exposures Among Children with Hematologic Malignancies

Free
Rahela Aziz-Bose, Morgan A. Paul, Yael Flamand, Colleen A. Kelly, Leanne Duhaney, Puja J. Umaretiya, Lucille Lokko, McKenzie Griffin, Alexandria Hawkins, Peter D. Cole, Lisa M. Gennarini, Justine M. Kahn, Kara M. Kelly, Victoria B. Koch, Bruno Michon, Thai Hoa Tran, Jennifer J.G. Welch, Lewis B. Silverman, Kira Bona
Journal: Blood
Blood (2024) 144 (Supplement 1): 3750.
https://doi.org/10.1182/blood-2024-205672
Published: 2024
Journal Articles

Efficacy and Toxicity of Fixed Dose Versus Reduced/PK-Adjusted Dose Pegaspargase in Pediatric Patients with Newly Diagnosed Acute Lymphoblastic Leukemia: Results of DFCI ALL Consortium Protocol 16-001

Free
Melissa A. Burns, Yael Flamand, Lynda M. Vrooman, Victoria B. Koch, Yves Theoret, Sarah M. Cronholm, Sarah K. Hunt, Peter D. Cole, Lisa M. Gennarini, Nobuko Hijiya, Justine M. Kahn, Kara M. Kelly, Bruno Michon, Donna S. Neuberg, Andrew E. Place, Thai Hoa Tran, Jennifer J.G. Welch, Stephen E. Sallan, Lewis B. Silverman
Journal: Blood
Blood (2024) 144 (Supplement 1): 307.
https://doi.org/10.1182/blood-2024-207273
Published: 2024
Journal Articles

Feasibility of Adjusting Risk Group and Risk Group-Based Therapy during Induction in the Treatment of B-Cell Acute Lymphoblastic Leukemia: Results from DFCI ALL Consortium Protocol 16-001

Free
Lynda M. Vrooman, Yael Flamand, Melissa A. Burns, Victoria B. Koch, Sarah M. Cronholm, Sarah K. Hunt, Peter D. Cole, Lisa M. Gennarini, Marian H. Harris, Nobuko Hijiya, Justine M. Kahn, Kara M. Kelly, Bruno Michon, Andrew E. Place, Thai Hoa Tran, Jennifer J.G. Welch, Stephen E. Sallan, Lewis B. Silverman
Journal: Blood
Blood (2024) 144 (Supplement 1): 311.
https://doi.org/10.1182/blood-2024-208605
Published: 2024
Journal Articles

ATM germ line pathogenic variants affect outcomes in children with ataxia-telangiectasia and hematological malignancies

Free
Clinical Trials & Observations
Sarah Elitzur, Ruth Shiloh, Jan L. C. Loeffen, Agata Pastorczak, Masatoshi Takagi, Simon Bomken, Andre Baruchel, Thomas Lehrnbecher, Sarah K. Tasian, Oussama Abla, Nira Arad-Cohen, Itziar Astigarraga, Miriam Ben-Harosh, Nicole Bodmer, Triantafyllia Brozou, Francesco Ceppi, Liliia Chugaeva, Luciano Dalla Pozza, Stephane Ducassou, Gabriele Escherich, Roula Farah, Amber Gibson, Henrik Hasle, Julieta Hoveyan, Elad Jacoby, Janez Jazbec, Stefanie Junk, Alexandra Kolenova, Jelena Lazic, Luca Lo Nigro, Nizar Mahlaoui, Lane Miller, Vassilios Papadakis, Lucie Pecheux, Marta Pillon, Ifat Sarouk, Jan Stary, Eftichia Stiakaki, Marion Strullu, Thai Hoa Tran, Marek Ussowicz, Jaime Verdu-Amoros, Anna Wakulinska, Joanna Zawitkowska, Dominique Stoppa-Lyonnet, A. Malcolm Taylor, Yosef Shiloh, Shai Izraeli, Veronique Minard-Colin, Kjeld Schmiegelow, Ronit Nirel, Andishe Attarbaschi, Arndt Borkhardt
Journal: Blood
Blood (2024) 144 (11): 1193–1205.
https://doi.org/10.1182/blood.2024024283
Published: 2024
Includes: Supplemental data
Journal Articles

Comparison of World Health Organization and International Consensus Classification Guidelines for Myeloid Neoplasms Harboring TP53 -Mutations Using an Independent International Cohort

Free
Mithun V Shah, Monika Kutyna, Syed Shah, Elizabeth Ngoc Hoa Tran, Anmol Baranwal, Dariusz Ladon, Aref Al-Kali, Anna Brown, Dong Chen, Patricia Greipp, Kebede Begna, Mark R. Litzow, William J. Hogan, Peter Bardy, Sharad Kumar, David T Yeung, Mrinal M. Patnaik, James M. Foran, Rong He, Naseema Gangat, Hamish S Scott, Cecilia Y. Arana Yi, Hassan Alkhateeb, Abhishek A Mangaonkar, Daniel Thomas, Christopher Norman Hahn, Attilio Orazi, Daniel A. Arber, Chung Hoow Kok, Ayalew Tefferi, Devendra Hiwase
Journal: Blood
Blood (2023) 142 (Supplement 1): 3243.
https://doi.org/10.1182/blood-2023-187860
Published: 2023
Journal Articles

Outcome of Infants Treated on Total Therapy for Infants with Acute Lymphoblastic Leukemia I: Results from a Non-Randomized Multi-Center Study

Free
Tanja A. Gruber, Minxuan Huang, Sima Jeha, Rebecca J. Deyell, Victor A. Lewis, Bill H. Chang, Eric J. Lowe, Jamie Frediani, Catherine Vezina, Bruno Michon, Nathan Gossai, Erin H. Breese, Thai Hoa Tran, Norman J. Lacayo, Christine Bolen, Sunil J. Desai, Jennifer L. Pauley, Emily Ashcraft, Cheng Cheng, Kirk R. Schultz, Krysta Schils, Linda C. Stork, Van Thu Huynh, Michael Richards, Yoav H. Messinger, Henrique Bittencourt, Terzah M. Horton, Uma Athale, Duncan Stearns, Deborah E. Schiff, Paul S. Gaynon
Journal: Blood
Blood (2023) 142 (Supplement 1): 823.
https://doi.org/10.1182/blood-2023-177798
Published: 2023
Journal Articles

Real-World Use, Effectiveness and Safety of Romiplostim, Eltrombopag and Avatrombopag in Immune Thrombocytopenia: Data from the Norwegian ITP Registry

Free
Riccardo Tomasello, Lamya Garabet, Heidi Pettersen, Eirik Tjønnfjord, Galina Tsykunova, Torkild Pedersen, Hoa Tran, Mariasanta Napolitano, Waleed Ghanima
Journal: Blood
Blood (2023) 142 (Supplement 1): 3952.
https://doi.org/10.1182/blood-2023-182848
Published: 2023
Journal Articles

Health Related Quality of Life in Patients with Primary ITP Compared with Population Norms: A Multicenter Retrospective Analysis of Data from Norwegian ITP Registry

Free
Riccardo Tomasello, Lamya Garabet, Heidi Pettersen, Hoa Tran, Mazdac Tavoly, Galina Tsykunova, Eirik Tjønnfjord, Mariasanta Napolitano, Waleed Ghanima
Journal: Blood
Blood (2023) 142 (Supplement 1): 3754.
https://doi.org/10.1182/blood-2023-188445
Published: 2023
Journal Articles

Trends of Obesity over Time and Its Prognostic Significance in Children and Adolescents with Newly-Diagnosed Acute Lymphoblastic Leukemia in Canada: A Population-Based Study

Free
Samuel Sassine, Marie-Claude Pelland-Marcotte, André Ilinca, Uma Athale, Henrique Bittencourt, Lynette Bowes, Josée Brossard, Sara J. Israels, Johnston Donna, Ketan Kulkarni, Sarah McKillop, Meera Rayar, Roona Sinha, Tony Truong, Catherine Vezina, Laura Wheaton, Alexandra Zorzi, Lillian Sung, Thai Hoa Tran
Journal: Blood
Blood (2023) 142 (Supplement 1): 3760.
https://doi.org/10.1182/blood-2023-178401
Published: 2023
Journal Articles

ATM Germline Pathogenic Variants Affect Treatment Outcomes in Children with Acute Lymphoblastic Leukemia/Lymphoma and Ataxia Telangiectasia

Free
Sarah Elitzur, Ruth Shiloh, Jan Loeffen, Agata Pastorczak, Masatoshi Takagi, Simon Bomken, Andre Baruchel, Stephane Ducassou, Nizar Mahlaoui, Marion Strullu, Thomas Lehrnbecher, Kjeld Schmiegelow, Oussama Abla, Liliia Anderzhanova, Nira Arad-Cohen, Itziar Astigarraga, Miriam Ben-Harosh, Francesco Ceppi, Nicole Bodmer, Triantafyllia Brozou, Luciano Dalla-Pozza, Gabriele Escherich, Roula Farah, Amber Gibson, Henrik Hasle, Julieta Hoveyan, Elad Jacoby, Janez Jazbec, Alexandra Kolenova, Jelena Lazic, Luca Lo Nigro, Lane Miller, Vassilios Papadakis, Lucie Pecheux, Marta Pillon, Ifat Sarouk, Jan Stary, Eftichia Stiakaki, Sarah K. Tasian, Thai Hoa Tran, Marek Ussowicz, Jose Jaime Verdu-Amoros, Anna Wakulinska, Joanna Zawitkowska, Dominique Stoppa-Lyonnet, Malcolm Taylor, Yosef Shiloh, Shai Izraeli, Ronit Nirel, Veronique Minard-Colin, Andishe Attarbaschi, Arndt Borkhardt
Journal: Blood
Blood (2023) 142 (Supplement 1): 520.
https://doi.org/10.1182/blood-2023-179333
Published: 2023