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François Lemonnier
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Journal Articles

Single-Cell Atlas of Diffuse Large B-Cell Lymphoma Reveals Integrated Malignant B Cell and Tumor Microenvironment Characteristics Associated with Clinical Response

Sabrina Baaklini, Alexandre Sarrabay, Adrien Mazuel, Bertrand Escaliere, Chuang Dong, Camille Barthelemy, Laurine Gil, Laila Dahbi, Noushin Mossadegh-Keller, Nathalie Van Acker, Pauline Gravelle, Jean-Marc Navarro, Caroline Huber, Romain Fenouil, Romane Trombetta, Marine Pujol, Philippe Gaulard, Benjamin Riviere, Peggy Dartigues, Francesco Llamas Gutierrez, Celine Pangault, Fabrice Jardin, François Lemonnier, Gilles Salles, Corinne Haioun, Gabriel Brisou, Matthew E. Stokes, Sahil Seth, Maria Ortiz Estevez, Camille Laurent, Lionel Spinelli, Mark Kaplan, C. Chris Huang, Anita K. Gandhi, Bertrand Nadel, Sandrine Roulland, Pierre Milpied
Journal: Blood
Blood (2024) 144 (Supplement 1): 1597.
https://doi.org/10.1182/blood-2024-209815
Published: 2024
Journal Articles

Health-Related Quality of Life after Axi-Cel As a Second-Line Therapy in Patients with High-Risk Relapsed/Refractory Large B-Cell Lymphoma Who Are Ineligible for Autologous Stem Cell Transplantation: Results of the Alycante Phase II Trial

Emilie Charton, Amelie Anota, Emmanuel Bachy, Guillaume Cartron, François-Xavier Gros, Franck Morschhauser, Lucie Oberic, Thomas Gastinne, Pierre Feugier, Remy Dulery, Catherine Thieblemont, Magalie Joris, Fabrice Jardin, Sylvain Choquet, Olivier Casasnovas, Gabriel Brisou, Morgane Cheminant, Jacques-Olivier Bay, Francesco Llamas Gutierrez, Cédric Portugues, Emmanuel Itti, Xavier Pallard, Paul Blanc-Durand, Yassine Al Tabaa, Clément Bailly, Camille Laurent, Francois Lemonnier, Roch Houot
Journal: Blood
Blood (2024) 144 (Supplement 1): 4505.
https://doi.org/10.1182/blood-2024-200614
Published: 2024
Journal Articles

Valemetostat Monotherapy in Patients with Relapsed or Refractory Large B-Cell Lymphoma: Primary Results of the Phase 2 Valym Study from the Lysa

Emmanuel Bachy, Bernard Drenou, Fabrice Jardin, Keiko Nakajima, Katell Le Du, Gandhi Damaj, Fontanet Bijou, Borhane Slama, Gian Matteo Pica, Gaetan Vanstraelen, Charles Herbaux, Roch Houot, Francois Lemonnier, Julie Gay, Pierre Sujobert, Marguerite Fournier, Marlene Ochmann, Romain Guieze, Jorge Zeron, Alexandra Traverse-Glehen, Jean Marc Schiano De Colella, Franck Morschhauser
Journal: Blood
Blood (2024) 144 (Supplement 1): 4479.
https://doi.org/10.1182/blood-2024-193960
Published: 2024
Journal Articles

PRIMAVERA: A Modular Phase I/II Study to Evaluate the Safety, Tolerability, and Efficacy of AZD3470, a Protein Arginine Methyltransferase 5 (PRMT5) Inhibitor, in Participants with Relapsed/Refractory Hematologic Malignancies

Tae Min Kim, Katharine L. Lewis, Juan Pablo Alderuccio, Hun Ju Lee, Enrico Derenzini, Pier Luigi Zinzani, Marco Ladetto, Elizabeth H. Phillips, Hervé Ghesquieres, François Lemonnier, Franck Morschhauser, Ana Sureda Balari, Antonia Rodriguez Izquierdo, Peter Borchmann, Matthew Weinstock, Jakub Svoboda, Emma Dean, Jelena Urosevic, Stefanie Meyer, Robert Chen, Richard Olsson, Kaitlyn Beyfuss, Graham P. Collins
Journal: Blood
Blood (2024) 144 (Supplement 1): 1674.2.
https://doi.org/10.1182/blood-2024-203060
Published: 2024
Journal Articles

Tazemetostat in Combination with R-CHOP in Patients with High-Risk, Frontline Follicular Lymphoma (Epi-RCHOP): A Phase II Study from the Lysa

Loic Ysebaert, Francois Lemonnier, Gabriel Brisou, Olivier Casasnovas, Gian Matteo Pica, Emmanuel Bachy, Ludovic Fouillet, Julie Abraham, Stephanie Guidez, Marc André, Guillaume Cartron, Romain Guieze, Sylvain Carras, Benoit Tessoulin, Roch Houot, Bohrane Slama, Christophe Bonnet, Luc-Matthieu Fornecker, Marie-Helene Delfau, Clementine Sarkozy, Camille Laurent, Vincent Ribrag, Franck Morschhauser
Journal: Blood
Blood (2023) 142 (Supplement 1): 297.
https://doi.org/10.1182/blood-2023-185057
Published: 2023
Journal Articles

A Single Cell Atlas of Diffuse Large B Cell Lymphomas Reveals Distinct Cellular States Predictive of Outcomes

Sabrina Baaklini, Alexandre Sarrabay, Camille Barthelemy, Laila Dahbi, Laurine Gil, Noushin Mossadegh-Keller, Jean-Marc Navarro, Caroline Huber, Romain Fenouil, Bertrand Escaliere, Romane Trombetta, Marine Pujol, Philippe Gaulard, Benjamin Riviere, Peggy Dartigues, Francesco Llamas Gutierrez, Celine Pangault, Fabrice Jardin, Francois Lemonnier, Gabriel Brisou, Corinne Haioun, Pauline Gravelle, Camille Laurent, Lionel Spinelli, C Chris Huang, Matthew E Stokes, Sahil Seth, Maria Ortiz, Anita K. Gandhi, Bertrand Nadel, Pierre Milpied, Sandrine Roulland
Journal: Blood
Blood (2023) 142 (Supplement 1): 848.
https://doi.org/10.1182/blood-2023-173929
Published: 2023
Journal Articles

Trial in Progress: A Randomized Phase II Study of MB-CART2019.1 Compared to Standard of Care Therapy in Patients with Relapsed/Refractory DLBCL Ineligible for High-Dose Chemotherapy and Autologous Stem Cell Transplantation - DALY 2-EU Trial

Peter Borchmann, Peter Vandenberghe, Alvaro Urbano-Ispizua, Corinne Haioun, Francois Lemonnier, Laimonas Griskevicius, Sébastien Maury, Silke Holtkamp, Birte Friedrichs, Gregor Zadoyan, Linda Hanssens, Toon Overstijns, Mario Assenmacher, Ulf Bethke, Iris Bürger, Olaf Reer, Ulrich Jaeger, Marie José Kersten
Journal: Blood
Blood (2022) 140 (Supplement 1): 12784–12785.
https://doi.org/10.1182/blood-2022-164650
Published: 2022
Journal Articles

Axicabtagene Ciloleucel As Second-Line Therapy for Large B-Cell Lymphoma in Transplant-Ineligible Patients: Primary Analysis of Alycante, a Phase 2 Lysa Study

Roch Houot, Emmanuel Bachy, Guillaume Cartron, François-Xavier Gros, Franck Morschhauser, Lucie Oberic, Thomas Gastinne, Pierre Feugier, Remy Dulery, Catherine Thieblemont, Magalie Joris, Francisco Llamas-Gutierrez, Emmanuel Itti, Cedric Menard, Yassine Al-Tabaa, Clement Bailly, Marie-Helene Delfau, Camille Laurent, Francois Lemonnier
Journal: Blood
Blood (2022) 140 (Supplement 1): 410–411.
https://doi.org/10.1182/blood-2022-156626
Published: 2022
Journal Articles

Oral Azacytidine in Patients with Relapsed/Refractory Angioimmunoblastic T-Cell Lymphoma: Final Analysis of the Oracle Phase III Study

Jehan Dupuis, Kunihiro Tsukasaki, Emmanuel Bachy, Franck Morschhauser, Guillaume Cartron, Noriko Fukuhara, Nicolas Daguindau, René-Olivier Casasnovas, Sylvia Snauwaert, Rémy Gressin, Christopher P. Fox, Francesco Annibale d'Amore, Philipp B. Staber, Argyrios Gkasiamis, Mitsufumi Nishio, Luc-Matthieu Fornecker, Marie-Helene Delfau, Nouhoum Sako, Sebastien Mule, Laurence De Leval, Philippe Gaulard, Francois Lemonnier
Journal: Blood
Blood (2022) 140 (Supplement 1): 2310–2312.
https://doi.org/10.1182/blood-2022-156789
Published: 2022
Journal Articles

Single-Cell and Spatial Analyses Characterize Distinct Subsets of Malignant T Cells in Angioimmunoblastic T Cell Lymphoma

Francois Lemonnier, Chuang Dong, Bruno Tesson, Laurine Gil, Noudjoud Attaf, Diana-Laure Mboumba, Philippe Gaulard, Pierre Milpied
Journal: Blood
Blood (2021) 138 (Supplement 1): 2393.
https://doi.org/10.1182/blood-2021-147246
Published: 2021
Journal Articles

Integrative Study of a High-Grade B-Cell Lymphoma Cohort of 45 Patients: A Single Institution Real Life Study

Louise Roulin, Elsa Poullot, Paul Blanc-Durand, Cyrielle Robe, Francois Lemonnier, Fabien Le Bras, Romain Gounot, Karim Belhadj, Jehan Dupuis, Mohammad Hammoud, Taoufik El Gnaoui, Sebastien Mule, Christiane Copie Bergman, Thierry Molina, Marie Helene Delfau Larue, Emmanuel Itti, Philippe Gaulard, Corinne Haioun
Journal: Blood
Blood (2021) 138 (Supplement 1): 4576.
https://doi.org/10.1182/blood-2021-152627
Published: 2021
Journal Articles

Preliminary Study of Ruxolitinib and Venetoclax for Treatment of Patients with T-Cell Prolymphocytic Leukemia Refractory to, or Ineligible for Alemtuzumab

Charles Herbaux, Stéphanie Poulain, Damien Roos-Weil, Jacques-Olivier Bay, Yann Guillermin, Francois Lemonnier, Kamel Laribi, Sorin Visanica, Jerome Moreaux, Hugo Gonzalez, Maxime Jullien, Abderrazak El Yamani, Houria Debarri, Sophie Godet, Franck Morschhauser, Olivier Tournilhac, Matthew S. Davids, Loic Ysebaert
Journal: Blood
Blood (2021) 138 (Supplement 1): 1201.
https://doi.org/10.1182/blood-2021-149228
Published: 2021
Journal Articles

BH3 profiling identifies ruxolitinib as a promising partner for venetoclax to treat T-cell prolymphocytic leukemia

Charles Herbaux, Christoph Kornauth, Stéphanie Poulain, Stephen J. F. Chong, Mary C. Collins, Rebecca Valentin, Liam Hackett, Olivier Tournilhac, François Lemonnier, Jehan Dupuis, Adrien Daniel, Cecile Tomowiak, Kamel Laribi, Loïc Renaud, Damien Roos-Weil, Cedric Rossi, Eric Van Den Neste, Cecile Leyronnas, Fatiha Merabet, Jean Valère Malfuson, Mourad Tiab, Loïc Ysebaert, Samuel Ng, Franck Morschhauser, Philipp B. Staber, Matthew S. Davids
Journal: Blood
Blood (2021) 137 (25): 3495–3506.
https://doi.org/10.1182/blood.2020007303
Published: 2021
Includes: Supplemental data
Journal Articles

Gene alterations in epigenetic modifiers and JAK-STAT signaling are frequent in breast implant–associated ALCL

Camille Laurent, Alina Nicolae, Cécile Laurent, Fabien Le Bras, Corinne Haioun, Virginie Fataccioli, Nadia Amara, José Adélaïde, Arnaud Guille, Jean-Marc Schiano, Bruno Tesson, Alexandra Traverse-Glehen, Marie-Pierre Chenard, Lénaïg Mescam, Anne Moreau, Catherine Chassagne-Clement, Joan Somja, Frédéric Escudié, Marc André, Nadine Martin, Laetitia Lacroix, François Lemonnier, Anne-Sophie Hamy, Fabien Reyal, Marie Bannier, Lucie Oberic, Nais Prade, François-Xavier Frénois, Asma Beldi-Ferchiou, Marie-Helene Delfau-Larue, Reda Bouabdallah, Daniel Birnbaum, Pierre Brousset, Luc Xerri, Philippe Gaulard
Journal: Blood
Blood (2020) 135 (5): 360–370.
https://doi.org/10.1182/blood.2019001904
Published: 2020
Includes: Supplemental data
Journal Articles

Rituximab Plus Gemcitabine and Oxaliplatin (R-GemOx) in Refractory/Relapsed (R/R) DLBCL. a Real Life Study in Patients Ineligible for Autologous Transplantation

Clarisse Cazelles, Karim Belhadj, Helene Vellemans, Vincent Camus, Christiane Copie, MD PhD, Liana Veresezan, MD, Emmanuel Itti, MD PhD, Stephanie Becker, MD, Muriel verlinde Carvalho, Jehan Dupuis, MD, Fabien Le Bras, Francois Lemonnier, MD PhD, Louise Roulin, MD, Taoufik El Gnaoui, Fabrice Jardin, Nicolas Mounier, MD, Herve Tilly, MD PhD, Corinne Haioun, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4115.
https://doi.org/10.1182/blood-2019-124143
Published: 2019
Journal Articles

Clinical, Immunophenotypic and Genetic Characteristics of Aggressive (non-Burkitt) B-Cell Lymphoma in a Real Life Cohort

Louise Roulin, MD, Jean-Philippe Jais, MD PhD, Alina Nicolae, MD PhD, Elsa Poullot, MD, Cyrielle Robe, Francois Lemonnier, MD PhD, Fabien Le Bras, Alizee Maarek, MD, Karim Belhadj, MD, Jehan Dupuis, MD, Elodie Scherman, MD, Mohammad Hammoud, MD, Taoufik El Gnaoui, MD, Sebastien Mule, MD PhD, Emmanuel Itti, MD PhD, Asma Beldi-Ferchiou, MD, Marie Helene Delfau Larue, MD PhD, Philippe Gaulard, MD PhD, Corinne Haioun, MD PhD, Christiane Copie, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4122.
https://doi.org/10.1182/blood-2019-123259
Published: 2019
Journal Articles

Genetic drivers of oncogenic pathways in molecular subgroups of peripheral T-cell lymphoma

Tayla B. Heavican, Alyssa Bouska, Jiayu Yu, Waseem Lone, Catalina Amador, Qiang Gong, Weiwei Zhang, Yuping Li, Bhavana J. Dave, Maarja-Liisa Nairismägi, Timothy C. Greiner, Julie Vose, Dennis D. Weisenburger, Cynthia Lachel, Chao Wang, Kai Fu, Jadd M. Stevens, Soon Thye Lim, Choon Kiat Ong, Randy D. Gascoyne, Edoardo Missiaglia, Francois Lemonnier, Corinne Haioun, Sylvia Hartmann, Martin Bjerregård Pedersen, Maria Antonella Laginestra, Ryan A. Wilcox, Bin Tean Teh, Noriaki Yoshida, Koichi Ohshima, Masao Seto, Andreas Rosenwald, German Ott, Elias Campo, Lisa M. Rimsza, Elaine S. Jaffe, Rita M. Braziel, Francesco d’Amore, Giorgio Inghirami, Francesco Bertoni, Laurence de Leval, Philippe Gaulard, Louis M. Staudt, Timothy W. McKeithan, Stefano Pileri, Wing C. Chan, Javeed Iqbal
Journal: Blood
Blood (2019) 133 (15): 1664–1676.
https://doi.org/10.1182/blood-2018-09-872549
Published: 2019
Includes: Supplemental data
Journal Articles

Lenalidomide in Combination with CHOP in Patients with Angioimmunoblastic T-Cell Lymphoma (AITL): Final Analysis of Clinical and Molecular Data of a Phase 2 Lysa Study

Francois Lemonnier, MD PhD, Violaine Safar, MD, Laurence de Leval, MD, Anne Ségolène Cottereau, Laura Pelletier, Cyrielle Robe, Emmanuel Bachy, MD PhD, Guillaume Cartron, Marie-Pierre Moles, Audrey Letourneau, Edoardo Missiaglia, Alain Jacques Delmer, MD, Reda Bouabdallah, Laurent Voillat, MD, Marie Parrens, Olivier Casasnovas, MD, Victoria Cacheux, Remy Gressin, Herve Tilly, MD, Marie-Helene Delfau, MD, Michel Meignan, Philippe Gaulard, MD, Corinne Haioun, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 999.
https://doi.org/10.1182/blood-2018-99-110354
Published: 2018
Journal Articles

Serum 2-Hydroxyglutarate in Angioimmunoblastic T Cell Lymphomas: A New Marker for IDH2 Mutation Detection and Monitoring

Sophie Broutin, PhD PharmD, Francois Lemonnier, MD PhD, Aurélie Dupuy, PhD, Julia Delahousse, Virginie Fataccioli, PhD, Vincent Ribrag, MD, Violaine Safar, MD, Laura Pelletier, Cyrielle Robe, Herve Tilly, MD, Anne Ségolène Cottereau, MD, Céline Bossard, MD, Laurence de Leval, MD, Marie-Helene Delfau, MD, Corinne Haioun, MD, Angelo Paci, PharmD, PhD, Philippe Gaulard, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2898.
https://doi.org/10.1182/blood-2018-99-115893
Published: 2018
Journal Articles

Treatment with 5-azacytidine induces a sustained response in patients with angioimmunoblastic T-cell lymphoma

Clinical Trials & Observations
François Lemonnier, Jehan Dupuis, Pierre Sujobert, Olivier Tournillhac, Morgane Cheminant, Clémentine Sarkozy, Laura Pelletier, Ambroise Marçais, Cyrielle Robe, Virginie Fataccioli, Corinne Haioun, Olivier Hermine, Philippe Gaulard, Richard Delarue
Journal: Blood
Blood (2018) 132 (21): 2305–2309.
https://doi.org/10.1182/blood-2018-04-840538
Published: 2018
Includes: Supplemental data