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Erica M. Sparkenbaugh
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Journal Articles

EPCR shedding light on sickle nephropathy

Erica M. Sparkenbaugh
Journal: Blood
Blood (2024) 144 (5): 472–474.
https://doi.org/10.1182/blood.2024025479
Published: 2024
Journal Articles

Factor XII contributes to thrombotic complications and vaso-occlusion in sickle cell disease

Erica M. Sparkenbaugh, Michael W. Henderson, Megan Miller-Awe, Christina Abrams, Anton Ilich, Fatima Trebak, Nirupama Ramadas, Shantel Vital, Dillon Bohinc, Kara L. Bane, Chunsheng Chen, Margi Patel, Michael Wallisch, Thomas Renné, Andras Gruber, Brian Cooley, David Gailani, Malgorzata Kasztan, Gregory M. Vercellotti, John D. Belcher, Felicity E. Gavins, Evi X. Stavrou, Nigel S. Key, Rafal Pawlinski
Journal: Blood
Blood (2023) 141 (15): 1871–1883.
https://doi.org/10.1182/blood.2022017074
Published: 2023
Includes: Multimedia, Supplemental data
Journal Articles

Plasmin-mediated cleavage of high-molecular-weight kininogen contributes to acetaminophen-induced acute liver failure

Michael W. Henderson, Erica M. Sparkenbaugh, Shaobin Wang, Anton Ilich, Denis F. Noubouossie, Reiner Mailer, Thomas Renné, Matthew J. Flick, James P. Luyendyk, Zu-Lin Chen, Sidney Strickland, R. Todd Stravitz, Keith R. McCrae, Nigel S. Key, Rafal Pawlinski
Journal: Blood
Blood (2021) 138 (3): 259–272.
https://doi.org/10.1182/blood.2020006198
Published: 2021
Includes: Supplemental data
Journal Articles

Targeting the AnxA1/Fpr2/ALX pathway regulates neutrophil function, promoting thromboinflammation resolution in sickle cell disease

Junaid Ansari, Elena Y. Senchenkova, Shantel A. Vital, Zaki Al-Yafeai, Gaganpreet Kaur, Erica M. Sparkenbaugh, A. Wayne Orr, Rafal Pawlinski, Robert P. Hebbel, D. Neil Granger, Paul Kubes, Felicity N. E. Gavins
Journal: Blood
Blood (2021) 137 (11): 1538–1549.
https://doi.org/10.1182/blood.2020009166
Published: 2021
Includes: Multimedia, Supplemental data
Journal Articles

Thrombin activation of PAR-1 contributes to microvascular stasis in mouse models of sickle cell disease

Brief Report
Erica M. Sparkenbaugh, Chunsheng Chen, Tomasz Brzoska, Julia Nguyen, Shaobin Wang, Gregory M. Vercellotti, Nigel S. Key, Prithu Sundd, John D. Belcher, Rafal Pawlinski
Journal: Blood
Blood (2020) 135 (20): 1783–1787.
https://doi.org/10.1182/blood.2019003543
Published: 2020
Includes: Multimedia, Supplemental data
Journal Articles

Red blood cells modulate structure and dynamics of venous clot formation in sickle cell disease

Camille Faes, Anton Ilich, Amandine Sotiaux, Erica M. Sparkenbaugh, Michael W. Henderson, Laura Buczek, Joan D. Beckman, Patrick Ellsworth, Denis F. Noubouossie, Lantarima Bhoopat, Mark Piegore, Céline Renoux, Wolfgang Bergmeier, Yara Park, Kenneth I. Ataga, Brian Cooley, Alisa S. Wolberg, Nigel S. Key, Rafal Pawlinski
Journal: Blood
Blood (2019) 133 (23): 2529–2541.
https://doi.org/10.1182/blood.2019000424
Published: 2019
Includes: Multimedia, Supplemental data
Journal Articles

FXIIa Differentially Regulates Thrombin Generation during Steady State and Vaso-Occlusive Crisis in Sickle Cell Mice

Erica M Sparkenbaugh, PhD, Camille Faes, PhD, Denis Noubouossie, MD PhD, Daniel K. Kirchhofer, PhD, András Gruber, MD, Nigel S. Key, MB, ChB, Rafal Pawlinski, PhD
Journal: Blood
Blood (2016) 128 (22): 162.
https://doi.org/10.1182/blood.V128.22.162.162
Published: 2016
Journal Articles

Alteration of the Structure and Dynamics of Venous Clot Formation in Human and Murine Sickle Cell Disease

Camille Faes, PhD, Anton Ilich, MD, Erica M Sparkenbaugh, PhD, Alisa S. Wolberg, PhD, Brian C. Cooley, PhD, Kenneth I. Ataga, MD, Nigel S. Key, MB, ChB, FRCP,, Rafal Pawlinski, PhD
Journal: Blood
Blood (2016) 128 (22): 2478.
https://doi.org/10.1182/blood.V128.22.2478.2478
Published: 2016
Journal Articles

Thrombin-independent contribution of tissue factor to inflammation and cardiac hypertrophy in a mouse model of sickle cell disease

Erica M. Sparkenbaugh, Pichika Chantrathammachart, Kasemsiri Chandarajoti, Nigel Mackman, Nigel S. Key, Rafal Pawlinski
Journal: Blood
Blood (2016) 127 (10): 1371–1373.
https://doi.org/10.1182/blood-2015-11-681114
Published: 2016
Journal Articles

Differential contribution of FXa and thrombin to vascular inflammation in a mouse model of sickle cell disease

Erica M. Sparkenbaugh, Pichika Chantrathammachart, Jacqueline Mickelson, Joanne van Ryn, Robert P. Hebbel, Dougald M. Monroe, Nigel Mackman, Nigel S. Key, Rafal Pawlinski
Journal: Blood
Blood (2014) 123 (11): 1747–1756.
https://doi.org/10.1182/blood-2013-08-523936
Published: 2014
Includes: Supplemental data
Journal Articles

Protease Activated Receptor 2 (PAR-2) Promotes Vascular Inflammation in a Mouse Model of Sickle Cell Disease

Pichika Chantrathammachart, MD, Erica M Sparkenbaugh, PhD, BS, Nigel Mackman, PhD, Nigel S Key, MBChB, Rafal Pawlinski, PhD
Journal: Blood
Blood (2012) 120 (21): 375.
https://doi.org/10.1182/blood.V120.21.375.375
Published: 2012
Journal Articles

Heme Induces Systemic Activation of Coagulation in Vivo in a Tissue Factor-Dependent Manner

Erica M Sparkenbaugh, PhD, BS, Pichika Chantrathammachart, MD, Nigel Mackman, PhD, Nigel S Key, MBChB, Rafal Pawlinski, PhD
Journal: Blood
Blood (2012) 120 (21): 820.
https://doi.org/10.1182/blood.V120.21.820.820
Published: 2012