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Journal Articles

Oncogene-induced maladaptive activation of trained immunity in the pathogenesis and treatment of Erdheim-Chester disease

Blood (2021) 138 (17): 1554–1569.

https://doi.org/10.1182/blood.2020009594

Published: 2021

Includes: Supplemental data

Journal Articles

α 1 -Antitrypsin infusion for treatment of steroid-resistant acute graft-versus-host disease

John M. Magenau, Steven C. Goldstein, Dan Peltier, Robert J. Soiffer, Thomas Braun, Attaphol Pawarode, Mary M. Riwes, Maggi Kennel, Joseph H. Antin, Corey S. Cutler, Vincent T. Ho, Edwin P. Alyea, III, Brian L. Parkin, Gregory A. Yanik, Sung Won Choi, Eli C. Lewis, Charles A. Dinarello, John Koreth, Pavan Reddy

Blood (2018) 131 (12): 1372–1379.

https://doi.org/10.1182/blood-2017-11-815746

Published: 2018

Includes: Supplemental data

Journal Articles

Vorinostat plus tacrolimus/methotrexate to prevent GVHD after myeloablative conditioning, unrelated donor HCT

Sung Won Choi, Thomas Braun, Israel Henig, Erin Gatza, John Magenau, Brian Parkin, Attaphol Pawarode, Mary Riwes, Greg Yanik, Charles A. Dinarello, Pavan Reddy

Blood (2017) 130 (15): 1760–1767.

https://doi.org/10.1182/blood-2017-06-790469

Published: 2017

Journal Articles

Development of Anti-IL-1R3 Monoclonal Antibodies for Treating Cancer and IL-1 Family-Mediated Inflammation

Jesper F Højen, MD, Megan K Taylor, Tania Azam, Stephan Fischer, Daniel A Pollyea, MD, Craig T Jordan, PhD, Charles A. Dinarello, MD

Blood (2016) 128 (22): 5224.

https://doi.org/10.1182/blood.V128.22.5224.5224

Published: 2016

Journal Articles

Histone deacetylase inhibition regulates inflammation and enhances Tregs after allogeneic hematopoietic cell transplantation in humans

Sung Won Choi, Erin Gatza, Guoqing Hou, Yaping Sun, Joel Whitfield, Yeohan Song, Katherine Oravecz-Wilson, Isao Tawara, Charles A. Dinarello, Pavan Reddy

Blood (2015) 125 (5): 815–819.

https://doi.org/10.1182/blood-2014-10-605238

Published: 2015

Includes: Supplemental data

Journal Articles

Alpha 1 Anti-Trypsin (AAT) Offers Potent Therapy for Steroid Resistant Gut Gvhd: Interim Results of a Phase I/II Clinical Study

A. Mario Q. Marcondes, MD PhD, Mohamed L. Sorror, MD, Ekapun Karoopongse, MD, Terry Furlong, NP, Marina Lesnikova, PhD, Sabina Janciauskiene, MD, Charles A. Dinarello, MD, H. Joachim Deeg, MD

Blood (2014) 124 (21): 3927.

https://doi.org/10.1182/blood.V124.21.3927.3927

Published: 2014

Journal Articles

α-1-Antitrypsin (AAT)–modified donor cells suppress GVHD but enhance the GVL effect: a role for mitochondrial bioenergetics

A. Mario Marcondes, Ekapun Karoopongse, Marina Lesnikova, Daciana Margineantu, Tobias Welte, Charles A. Dinarello, David Hockenbery, Sabina Janciauskiene, H. Joachim Deeg

Blood (2014) 124 (18): 2881–2891.

https://doi.org/10.1182/blood-2014-04-570440

Published: 2014

Includes: Supplemental data

Journal Articles

The C3a receptor, caspase-1, and release of IL-1β

Charles A. Dinarello

Blood (2013) 122 (20): 3394–3395.

https://doi.org/10.1182/blood-2013-08-518282

Published: 2013

Journal Articles

Donor Treatment with α1 Anti-Trypsin (AAT) Mitigates Gvhd and Increases Survival While Sparing GVL Effects

A. Mario Q. Marcondes, MD, PhD, Ekapun Karoopongse, MD, Marina Lesnikova, PhD, Sabina Janciauskiene, MD, Charles A. Dinarello, M.D., H. Joachim Deeg, MD

Blood (2012) 120 (21): 1889.

https://doi.org/10.1182/blood.V120.21.1889.1889

Published: 2012

Journal Articles

α1 Anti-Trypsin (AAT) Mitigates Hematopoietic Injury and Enhances Bone Marrow Recovery After Total Body Irradiation (TBI)

Ekapun Karoopongse, MD, Sabina Janciauskiene, MD, Charles A. Dinarello, M.D., H. Joachim Deeg, A. Mario Q. Marcondes, MD, PhD

Blood (2012) 120 (21): 4142.

https://doi.org/10.1182/blood.V120.21.4142.4142

Published: 2012

Journal Articles

Targeting Histone Deacetylases As a New Strategy for Graft Versus Host Disease Prevention

Blood (2012) 120 (21): 740.

https://doi.org/10.1182/blood.V120.21.740.740

Published: 2012

Journal Articles

Keep up the heat on IL-1

Charles A. Dinarello

Blood (2012) 120 (13): 2538–2539.

https://doi.org/10.1182/blood-2012-08-445254

Published: 2012

Journal Articles

Inhibition of IL-32 activation by α-1 antitrypsin suppresses alloreactivity and increases survival in an allogeneic murine marrow transplantation model

A. Mario Marcondes, Xiang Li, Laura Tabellini, Matthias Bartenstein, Julia Kabacka, George E. Sale, John A. Hansen, Charles A. Dinarello, H. Joachim Deeg

Blood (2011) 118 (18): 5031–5039.

https://doi.org/10.1182/blood-2011-07-365247

Published: 2011

Journal Articles

Interleukin-1 in the pathogenesis and treatment of inflammatory diseases

Charles A. Dinarello

Blood (2011) 117 (14): 3720–3732.

https://doi.org/10.1182/blood-2010-07-273417

Published: 2011

Journal Articles

Interleukin-32, α1 Anti-Trypsin (AAT-1) and Graft-Versus-Host-Disease

A. Mario Q. Marcondes, MD, PhD, Laura Tabellini, John A. Hansen, MD, Charles A. Dinarello, MD, H. Joachim Deeg, MD

Blood (2010) 116 (21): 522.

https://doi.org/10.1182/blood.V116.21.522.522

Published: 2010

Journal Articles

Differential requirement for the activation of the inflammasome for processing and release of IL-1β in monocytes and macrophages

Mihai G. Netea, Claudia A. Nold-Petry, Marcel F. Nold, Leo A. B. Joosten, Bastian Opitz, Jonathan H. M. van der Meer, Frank L. van de Veerdonk, Gerben Ferwerda, Bas Heinhuis, Isabel Devesa, C. Joel Funk, Robert J. Mason, Bart Jan Kullberg, Anna Rubartelli, Jos W. M. van der Meer, Charles A. Dinarello

Blood (2009) 113 (10): 2324–2335.

https://doi.org/10.1182/blood-2008-03-146720

Published: 2009

Journal Articles

Histone deacetylase inhibitors prevent exocytosis of interleukin-1β-containing secretory lysosomes: role of microtubules

Sonia Carta, Sara Tassi, Claudia Semino, Gianluca Fossati, Paolo Mascagni, Charles A. Dinarello, Anna Rubartelli

Blood (2006) 108 (5): 1618–1626.

https://doi.org/10.1182/blood-2006-03-014126

Published: 2006

Journal Articles

Severe imbalance of IL-18/IL-18BP in patients with secondary hemophagocytic syndrome

Karin Mazodier, Valérie Marin, Daniela Novick, Catherine Farnarier, Stéphane Robitail, Nicolas Schleinitz, Véronique Veit, Pascale Paul, Menachem Rubinstein, Charles A. Dinarello, Jean-Robert Harlé, Gilles Kaplanski

Blood (2005) 106 (10): 3483–3489.

https://doi.org/10.1182/blood-2005-05-1980

Published: 2005

Journal Articles

The p38 mitogen-activated protein kinase pathway plays a critical role in thrombin-induced endothelial chemokine production and leukocyte recruitment

Valérie Marin, Catherine Farnarier, Sandra Grès, Solange Kaplanski, Michael S.-S. Su, Charles A. Dinarello, Gilles Kaplanski

Blood (2001) 98 (3): 667–673.

https://doi.org/10.1182/blood.V98.3.667

Published: 2001

Journal Articles

Interleukin-18 Regulation of Interferon γ Production and Cell Proliferation as Shown in Interleukin-1β–Converting Enzyme (Caspase-1)-Deficient Mice

Giamila Fantuzzi, Adrian J. Puren, Matthew W. Harding, David J. Livingston, Charles A. Dinarello

Blood (1998) 91 (6): 2118–2125.

https://doi.org/10.1182/blood.V91.6.2118

Published: 1998

NARROW

Oncogene-induced maladaptive activation of trained immunity in the pathogenesis and treatment of Erdheim-Chester disease

α 1 -Antitrypsin infusion for treatment of steroid-resistant acute graft-versus-host disease

Vorinostat plus tacrolimus/methotrexate to prevent GVHD after myeloablative conditioning, unrelated donor HCT

Development of Anti-IL-1R3 Monoclonal Antibodies for Treating Cancer and IL-1 Family-Mediated Inflammation

Histone deacetylase inhibition regulates inflammation and enhances Tregs after allogeneic hematopoietic cell transplantation in humans

Alpha 1 Anti-Trypsin (AAT) Offers Potent Therapy for Steroid Resistant Gut Gvhd: Interim Results of a Phase I/II Clinical Study

α-1-Antitrypsin (AAT)–modified donor cells suppress GVHD but enhance the GVL effect: a role for mitochondrial bioenergetics

The C3a receptor, caspase-1, and release of IL-1β

Donor Treatment with α1 Anti-Trypsin (AAT) Mitigates Gvhd and Increases Survival While Sparing GVL Effects

α1 Anti-Trypsin (AAT) Mitigates Hematopoietic Injury and Enhances Bone Marrow Recovery After Total Body Irradiation (TBI)

Targeting Histone Deacetylases As a New Strategy for Graft Versus Host Disease Prevention

Keep up the heat on IL-1

Inhibition of IL-32 activation by α-1 antitrypsin suppresses alloreactivity and increases survival in an allogeneic murine marrow transplantation model

Interleukin-1 in the pathogenesis and treatment of inflammatory diseases

Interleukin-32, α1 Anti-Trypsin (AAT-1) and Graft-Versus-Host-Disease

Differential requirement for the activation of the inflammasome for processing and release of IL-1β in monocytes and macrophages

Histone deacetylase inhibitors prevent exocytosis of interleukin-1β-containing secretory lysosomes: role of microtubules

Severe imbalance of IL-18/IL-18BP in patients with secondary hemophagocytic syndrome

The p38 mitogen-activated protein kinase pathway plays a critical role in thrombin-induced endothelial chemokine production and leukocyte recruitment

Interleukin-18 Regulation of Interferon γ Production and Cell Proliferation as Shown in Interleukin-1β–Converting Enzyme (Caspase-1)-Deficient Mice

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American Society of Hematology

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ASH Publications

American Society of Hematology

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