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Bernhard Küster
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Journal Articles

Boosting CAR T-Cell Efficacy by Blocking Proteasomal Degradation of Membrane Antigens

Open Access
Leonie Rieger, Kilian Irlinger, Franziska Füchsl, Marlene Tietje, Anna Purcarea, Nicolas Mathis Barbian, Melanie Faber, Carolin Vogelsang, Lisa Pfeuffer, Sonja Stotz, Oleksandra Karpiuk, Tobias Schulze, Abirami Augsburger, Nadine Glaisner, Verena Konetzki, Sabrina Friedel, Andrej Besse, Lenka Besse, Christoph Driessen, Maike Buchner, Kristina Schwamborn, Katja Steiger, Piero Giansanti, Sebastian Theurich, Johannes M. Waldschmidt, Klaus Martin Kortüm, Michael Hudecek, Hermann Einsele, Marion Högner, Bernhard Kuster, Angela Krackhardt, Judith S. Hecker, Florian Bassermann
Journal: Blood
Blood blood.2024027616.
https://doi.org/10.1182/blood.2024027616
Published: 2025
Includes: Supplemental data
Journal Articles

Pathogenesis and Clinical Relevance of Diffuse Large B-Cell Lymphoma Proteogenotypes

Free
Julius C. Enssle, Björn Häupl, Arber Qoku, Boya Wang, George W. Wright, Sharon Barrans, Matthew Anthony Care, Cathy Burton, Caitlin Gribbin, Sebastian Scheich, Sebastian Wolf, James D. Phelan, Da Wei Huang, Andrea diFonzo, Martine Pape, Marion Bodach, Dominique Jahn, Uwe Plessmann, Daniel J Hodson, Bernhard Kuster, Roland Schmitz, Henning Urlaub, Reuben Tooze, Giorgio Inghirami, Florian Buettner, Louis M. Staudt, Thomas Oellerich
Journal: Blood
Blood (2024) 144 (Supplement 1): 229.
https://doi.org/10.1182/blood-2024-204606
Published: 2024
Journal Articles

Multi-Omics Analysis of Proteasome Inhibitor Resistance in Multiple Myeloma

Free
Seungbin Han, Chien-Yun Lee, Lenka Besse, Umair Munawar, Andrej Besse, Ann-Sohpie Hainold, Silvia Nerreter, Cornelia Vogt, Shilpa Kurian, Xiang Zhou, Larissa Haertle, Johannes Waldschmidt, Christoph Driessen, Hermann Einsele, Leo Rasche, Bernhard Kuster, K. Martin Kortüm
Journal: Blood
Blood (2024) 144 (Supplement 1): 6817.
https://doi.org/10.1182/blood-2024-203352
Published: 2024
Journal Articles

Regulation of BCMA By the Ubiquitin Proteasome System Enables Optimization of BCMA-Targeting Therapies in Multiple Myeloma

Free
Leonie Rieger, Kilian Irlinger, Franziska Fuechsl, Nicolas Barbian, Marlene Tietje, Melanie Faber, Tobias Schulze, Piero Giansanti, Lenka Besse, Christoph Driessen, Angela Krackhardt, Bernhard Kuster, Florian Bassermann
Journal: Blood
Blood (2023) 142 (Supplement 1): 3310.
https://doi.org/10.1182/blood-2023-187349
Published: 2023
Journal Articles

Impact of ABCB1 Promoter Methylation on PI-Resistance in Multiple Myeloma

Free
Seungbin Han, Larissa Haertle, Lenka Besse, Chien-Yun Lee, Xiang Zhou, Umair Munawar, Andrej Besse, Miriam Kull, Max Bittrich, Max Johannes Steinhardt, Julia Mersi, Eva Teufel, Silvia Nerreter, Cornelia Vogt, Sophia Danhof, Jan Krönke, Niels Weinhold, Marc S Raab, Thomas Haaf, Christoph Driessen, Hermann Einsele, Leo Rasche, Bernhard Küster, Martin Kortuem
Journal: Blood
Blood (2022) 140 (Supplement 1): 12462–12463.
https://doi.org/10.1182/blood-2022-168694
Published: 2022
Journal Articles

Synergistic Antileukemic Effect of Mek and Lsd1 Inhibitors Correlates with Decreased Phospho-Serine 315 of TP53

Free
Alessandra Caroleo, Paul Kerbs, Anja Swoboda, Lucas Wange, Stephanie Heinzlmeir, Yun-Chien Chang, Bernhard Küster, Wolfgang Enard, Michael von Bergwelt, Philipp A. Greif, Monica Cusan
Journal: Blood
Blood (2022) 140 (Supplement 1): 5870–5871.
https://doi.org/10.1182/blood-2022-169202
Published: 2022
Journal Articles

Negative Feedback Regulation of MAPK Signaling Is an Important Driver of CLL Progression

Free
Lisa Brandmeier, Veronika Ecker, Martina Stumpf, Piero Giansanti, Aida Varela Moreira, Lisa Pfeuffer, Marcel Fens, Junyan Lu, Bernhard Küster, Thomas Engleitner, Simon Heidegger, Ingo Ringshausen, Thorsten Zenz, Clemens-Martin Wendtner, Markus Müschen, Jürgen Ruland, Maike Buchner
Journal: Blood
Blood (2022) 140 (Supplement 1): 9840–9841.
https://doi.org/10.1182/blood-2022-160103
Published: 2022
Journal Articles

The Fanconi Anemia-Associated Protein NIPA Is Essential for the Nuclear Abundance of FANCD2

Free
Stefanie Kreutmair, Miriam Erlacher, Geoffroy Andrieux, Rouzanna Istvanffy, Alina Rudorf, Melissa Zwick, Tamina Rückert, Milena Pantic, Teresa Poggio, Khalid Shoumariyeh, MD, Tony Andreas Müller, Hiroyuki Kawaguchi, Marie Follo, Cathrin Klingeberg, Marcin Wlodarski, Irith Baumann, Dietmar Pfeifer, Michal Kulinski, Martina Rudelius, Simone Lemeer, Bernhard Kuster, Christine Dierks, Christian Peschel, Nina Cabezas-Wallscheid, Jesus Duque-Afonso, Robert Zeiser, MD, Michael Cleary, Detlev Schindler, Annette Schmitt-Graeff, Melanie Boerries, Charlotte M. Niemeyer, MD, Robert A.J. Oostendorp, Justus Duyster, MD, Anna Lena Illert
Journal: Blood
Blood (2019) 134 (Supplement_1): 3741.
https://doi.org/10.1182/blood-2019-125973
Published: 2019
Journal Articles

The IMiD-Target Cereblon Determines Transmembrane Protein Quality Control Promoting Tumor Metabolism

Free
Michael Heider, Ruth Eichner, Jacob Stroh, Anna Kuisl, Jana Zecha, Jannis Lawatscheck, Martina Rudelius, Anne-Kathrin Garz, Simone Lemeer, Christian Peschel, Ulrich Keller, MD, Katharina Götze, Johannes Buchner, Bernhard Kuster, Vanesa Fernandez-Saiz, Florian Bassermann, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 314.
https://doi.org/10.1182/blood-2019-129064
Published: 2019
Journal Articles

Deciphering The Molecular Impact Of Myc Overexpression On B Cell Receptor Signaling and Its Implications For Burkitt Lymphoma Treatment

Free
Thomas Oellerich, Jasmin Corso, Simone Lemeer, Ekkehard Schütz, Julia Beck, Stephan Lorenzen, Tim Beissbarth, Silvia Münch, Pascal Degenhardt, Michael Engelke, Christoph Lenz, Bernhard Küster, Henning Urlaub, Hubert Serve, MD
Journal: Blood
Blood (2013) 122 (21): 3018.
https://doi.org/10.1182/blood.V122.21.3018.3018
Published: 2013