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Antonio Curti, MD
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Journal Articles

Vascular and Parenchymal Alterations of the Liver and Liver Surveillance in Patients Who Received Inotuzumab Ozogamicin As the Standard of Care for Relapse/Refractory Acute Lymphoblastic Leukemia

Giovanni Marconi, Federico Ravaioli, MD, Giovanni Martinelli, MD, Elton Dajti, Maria Chiara Abbenante, MD, Chiara Sartor, MD, Luigina Vanessa Alemanni, MD, Jacopo Nanni, MD, Sarah Parisi, MD PhD, Giovanni Marasco, MD, Gianluca Cristiano, MD, Amanda Vestito, MD, Francesca Bonifazi, Stefania Paolini, MD PhD, Antonio Curti, MD PhD, Davide Festi, MD, Michele Cavo, Cristina Papayannidis, Antonio Colecchia, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1343.
https://doi.org/10.1182/blood-2019-130632
Published: 2019
Journal Articles

The Use of Venetoclax for Acute Myeloid Leukemia in a Real-Life Setting: A Multicenter National Experience

Jacopo Nanni, MD, Giacomo Gianfaldoni, MD, Gianluca Cristiano, Giovanni Marconi, Matteo Piccini, MD, Pietro Grieco, Sr., MD, Sofia Pilerci, Sr., MD, Michele Gottardi, Marco Cerrano, MD, Sarah Parisi, MD PhD, Chiara Sartor, MD, Emanuela Ottaviani, Lorenza Baldini, MSc, Nicoletta Testoni, Carmen Baldazzi, PhD, Stefania Paolini, MD PhD, Filippo Gherlinzoni, MD, Alberto Bosi, MD, Mario Boccadoro, Michele Cavo, Cristina Papayannidis, Antonio Curti, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5098.
https://doi.org/10.1182/blood-2019-128583
Published: 2019
Journal Articles

An IDO1 -Related 3-Gene Signature Predicts Overall Survival in Intermediate-Risk Acute Myeloid Leukemia

Simone Ragaini, MD, Sarah Wagner, BSc MSc, Giovanni Marconi, Sarah Parisi, MD PhD, Chiara Sartor, MD, Jacopo Nanni, MD, Gianluca Cristiano, Annalisa Talami, MD, Matteo Olivi, MD, Darina Ocadlikova, PhD, Marilena Ciciarello, PhD, Giulia Corradi, PhD, Emanuela Ottaviani, Cristina Papayannidis, Stefania Paolini, MD PhD, Jayakumar Vadakekolathu, PhD, Michele Cavo, Sergio Rutella, MD PhD FRCPath, Antonio Curti, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5193.
https://doi.org/10.1182/blood-2019-128348
Published: 2019
Journal Articles

AML-CM Score Predicts Prognosis in Hemato-Geriatric Patients with New-Onset Acute Myeloid Leukemia (AML) Who Receive Hypomethylating Agents (HMA)

Giovanni Marconi, Roberta di Nicola, Chiara Sartor, MD, Mariachiara Abbenante, MD, Jacopo Nanni, MD, Gianluca Cristiano, MD, Sarah Parisi, MD PhD, Carmen Baldazzi, PhD, Maria Chiara Fontana, PhD, Lorenza Bandini, Emanuela Ottaviani, Nicoletta Testoni, Giovanni Martinelli, MD, Michele Baccarani, MD, Cristina Papayannidis, Stefania Paolini, MD PhD, Michele Cavo, Antonio Curti, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2617.
https://doi.org/10.1182/blood-2019-130630
Published: 2019
Journal Articles

In Systemic Masocytosis, Midostaurin Targets Both Kit and Aurora Kinase a Reverting H3K36Me3 Deficiency and Synergizes with Second-Generation Tyrosine Kinase Inhibitors

Manuela Mancini, PhD, Cecilia Monaldi, Dr, Sara De Santis, Dr, Cristina Papayannidis, Michela Rondoni, MD, Luana Bavaro, Dr, Margherita Martelli, Dr, Antonio Curti, MD PhD, Maria Chiara Fontana, PhD, Samantha Bruno, Dr, Roberta Zanotti, MD, Massimiliano Bonifacio, MD, Luigi Scaffidi, MD, Livio Pagano, MD, Marianna Criscuolo, MD, Francesco Albano, MD, Fabio Ciceri, MD, Chiara Elena, MD, Patrizia Tosi, Massimo Delledonne, Carla Avanzato, Luciano Xumerle, Peter Valent, MD, Giovanni Martinelli, Michele Cavo, Simona Soverini, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4204.
https://doi.org/10.1182/blood-2019-126538
Published: 2019
Journal Articles

Mechanisms of Tolerance Induction through T Regulatory Cells during Chemotherapy-Mediated Immunogenic Cell Death in Acute Myeloid Leukemia

Darina Ocadlikova, PhD, Serenella Casella, Ines Pintao, Elena Adinolfi, Sabina Sangaletti, PhD, Elena De Marchi, Anna Pegoraro, Elisa Orioli, Mario Paolo Colombo, Francesco Di Virgilio, Michele Cavo, Antonio Curti, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2332.
https://doi.org/10.1182/blood-2019-126478
Published: 2019
Journal Articles

Interferon-γ-Dependent Inflammatory Signature in Acute Myeloid Leukemia Cells Is Able to Shape Stromal and Immune Bone Marrow Microenvironment

Marilena Ciciarello, PhD, Giulia Corradi, PhD, Sabina Sangaletti, PhD, Barbara Bassani, Giorgia Simonetti, PhD, Jayakumar Vadakekolathu, PhD, Giovanni Marconi, Giovanni Martinelli, MD, Mario Paolo Colombo, Sergio Rutella, MDPhDFRCPath, Michele Cavo, Antonio Curti, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1212.
https://doi.org/10.1182/blood-2019-126512
Published: 2019
Journal Articles

Bitter Taste Receptors Are Expressed on Acute Myeloid Leukemia Cells and Their Activation Results in Quiescence Induction and Prevention of Migration

Valentina Salvestrini, PhD, Marilena Ciciarello, Giorgia Simonetti, PhD, Giovanni Martinelli, MD, Michele Cavo, MD, Antonio Curti, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3949.
https://doi.org/10.1182/blood.V130.Suppl_1.3949.3949
Published: 2017
Journal Articles

Chemotherapy-Dependent ATP Release from Leukemia Dying Cells Induces Indoleamine 2,3-Dioxygenase 1 in Dendritic Cells

Mariangela Lecciso, PhD, Darina Ocadlikova, PhD, Elena De Marchi, M.S., Elisa Orioli, Sabina Sangaletti, PhD, Sara Trabanelli, PhD, Camilla Jandus, MD PhD, Andrea Bontadini, Annarita Redavid, Pedro Romero, professor, Mario Paolo Colombo, M.S., Francesco Di Virgilio, Giovanni Martinelli, Michele Cavo, MD, Elena Adinolfi, Antonio Curti, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3711.
https://doi.org/10.1182/blood.V128.22.3711.3711
Published: 2016
Journal Articles

The Induction of Inhibitory Pathways in Dendritic Cells May Hamper the Efficient Activation of Anti-Leukemia T Cells within Chemotherapy-Induced Immunogenic Cell Death

Darina Ocadlikova, PhD, Mariangela Lecciso, M.S., Elisa Orioli, M.S., Elena De Marchi, M.S., Sabina Sangaletti, PhD, Sara Trabanelli, PhD, Camilla Jandus, PhD, Valentina Salvestrini, PhD, Pedro Romero, professor, Mario Paolo Colombo, M.S., Francesco Di Virgilio, Roberto M Lemoli, Professor, Michele Cavo, Elena Adinolfi, Antonio Curti, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1019.
https://doi.org/10.1182/blood.V126.23.1019.1019
Published: 2015
Journal Articles

Upregulation of Indoleamine 2,3-Dioxygenase Enzymes in Leukemic Mesenchymal Stromal Cells (MSCs) Can Influence MSC/Acute Myeloid Leukemia Cell Cross Talk

Marilena Ciciarello, PhD, Giulia Corradi, PhDstudent, Carmen Baldazzi, PhD, Nicoletta Testoni, Professor, Roberto Massimo Lemoli, MD, Michele Cavo, Antonio Curti, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1191.
https://doi.org/10.1182/blood.V126.23.1191.1191
Published: 2015
Journal Articles

The Tissue Inhibitor of Metalloproteinases-1 (TIMP-1) Regulates the Function and Migration of Leukemic Blasts through CD63/PI3K/AKT/P21 Axis

Dorian Forte, PhD Student, Valentina Salvestrini, PhD, Lucia Catani, PhD, Roberto M Lemoli, Professor, Michele Cavo, Antonio Curti, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2394.
https://doi.org/10.1182/blood.V126.23.2394.2394
Published: 2015
Journal Articles

Two or More Chemotherapy Consolidation Courses, Followed By Autologous Bone Marrow Transplantation, and MRD Negativity, Give Long Term Overall Survival in Acute Myeloid Leukemia Patients

Giovanni Marconi, MD, Cristina Papayannidis, MD PhD, Federico Mosna, Michele Gottardi, Giorgia Simonetti, PhD, Simona Soverini, Antonio Curti, MD PhD, Elisa Zuffa, PhD, Maria Chiara Abbenante, MD, Sarah Parisi, MD, Stefania Paolini, MD, Chiara Sartor, Eugenia Franchini, Emanuela Ottaviani, Claudia Venturi, PhD, Maria Chiara Fontana, Antonella Padella, Viviana Guadagnuolo, PhD, Maria Teresa Bochicchio, Anna Ferrari, PhD, Nicoletta Testoni, Carmen Baldazzi, PhD, Marco Manfrini, PhD, Debora Capelli, MD, Piero Galieni, Andrea Piccin, MD, Giuseppe Visani, MD, Francesco Rodeghiero, Cristina Tecchio, Filippo Gherlinzoni, MD, Michele Cavo, Giovanni Martinelli, MD PhD
Journal: Blood
Blood (2015) 126 (23): 3198.
https://doi.org/10.1182/blood.V126.23.3198.3198
Published: 2015
Journal Articles

P2X7 Receptor Activation By ATP As Target of Novel Therapies in Acute Myeloid Leukemia

Valentina Salvestrini, Stefania Orecchioni, Francesca Reggiani, Giovanna Talarico, Elisa Orioli, Elena Adinolfi, Francesco Bertolini, Francesco Di Virgilio, Michele Cavo, Roberto Massimo Lemoli, MD, Antonio Curti, MD PhD
Journal: Blood
Blood (2015) 126 (23): 3684.
https://doi.org/10.1182/blood.V126.23.3684.3684
Published: 2015
Journal Articles

Treating Ph+ Acute Lymphoblastic Leukemia (ALL) in the Elderly: The Sequence of Two Tyrosine Kinase Inhibitors (TKI) (Nilotinib and Imatinib) Does Not Prevent Mutations and Relapse.

Cristina Papayannidis, Paola Fazi, MD, Alfonso Piciocchi, Francesco Di Raimondo, Giovanni Pizzolo, MD, Angelo Michele Carella, MD, Mario Cazzola, Antonio Cuneo, MD, Pietro Leoni, MD, Mario Luppi, Enrica Morra, MD, Giorgina Specchia, MD, Emanuele Angelucci, MD, Monica Bocchia, Renato Fanin, MD, Giuseppe Saglio, MD, Daniele Vallisa, MD, Sandra De Simone, Antonella Vitale, Ilaria Iacobucci, Simona Soverini, Anna Ferrari, Claudia Venturi, Caterina De Benedittis, Nicoletta Testoni, Antonio Curti, MD, Stefania Paolini, Miriam Fogli, Giovanni Martinelli, Michele Baccarani, MD
Journal: Blood
Blood (2012) 120 (21): 2601.
https://doi.org/10.1182/blood.V120.21.2601.2601
Published: 2012
Journal Articles

Human Blood Dendritic Cells Induce Tregs Through the PGE2-Independent Expression of an Active Form of IDO2 Enzyme

Sara Trabanelli, Darina Ocadlikova, Marilena Ciciarello, Valentina Salvestrini, Cecilia Evangelisti, Richard Metz, Lisa Laury-Kleintop, George Prendergast, Antonio Curti, MD, Roberto M. Lemoli
Journal: Blood
Blood (2012) 120 (21): 1047.
https://doi.org/10.1182/blood.V120.21.1047.1047
Published: 2012
Journal Articles

Gas1 and Kif27 Genes Are Strongly up-Regulated Biomarkers of Hedgehog Inhibition (PF-04449913) on Leukemia Stem Cells in Phase I Acute Myeloid Leukemia and Chronic Myeloid Leukemia Treated Patients

Viviana Guadagnuolo, Cristina Papayannidis, Ilaria Iacobucci, PhD, Sandra Durante, Carolina Terragna, PhD, Emanuela Ottaviani, Maria Chiara Abbenante, Federica Cattina, MD, Simona Soverini, Barbara Lama, Lucia Toni, Wendy J. Levin, MD, MS, Rachel Courtney, PhD, Carmen Baldazzi, Antonio Curti, MD, Michele Baccarani, MD, Catriona Jamieson, MD, Ph.D., Jorge E. Cortes, Vivian Oehler, MD, Karen McLachlan, Todd Van Arsdale, PhD, Giovanni Martinelli, MD
Journal: Blood
Blood (2011) 118 (21): 1535.
https://doi.org/10.1182/blood.V118.21.1535.1535
Published: 2011
Journal Articles

PGE 2 -Independent Expression of Indoleamine 2,3-Dioxygenase-2 (IDO2) Supports the Tolerogenic Function of Monocyte-Derived Dendritic Cells,

Sara Trabanelli, Antonio Curti, MD, Darina Ocadlikova, Cecilia Evangelisti, Valentina Salvestrini, Marilena Ciciarello, Michela Aluigi, PhD, Lara Rossi, Richard Metz, Lisa Laury-Kleintop, George Prendergast, Roberto M. Lemoli, MD
Journal: Blood
Blood (2011) 118 (21): 3231.
https://doi.org/10.1182/blood.V118.21.3231.3231
Published: 2011
Journal Articles

Integrin Alpha E (CD103) Beta 7 Expression Marks A Subset of Human Bone Marrow-Derived CD207 + Dendritic Cells Which Induce T Regulatory Cells Via Indoleamine 2,3-Dioxygenase,

Antonio Curti, MD, Darina Ocadlikova, Sara Trabanelli, Cecilia Evangelisti, Marilena Ciciarello, Michele Baccarani, MD, Roberto M. Lemoli, MD
Journal: Blood
Blood (2011) 118 (21): 3233.
https://doi.org/10.1182/blood.V118.21.3233.3233
Published: 2011
Journal Articles

CD4 + T-Cell Functions Are Modulated by the Extracellular ATP Concentration

Sara Trabanelli, Darina Ocadlikova, Sara Gulinelli, Marco Idzko, M.D., Antonio Curti, MD, Francesco Di Virgilio, Davide Ferrari, Roberto M. Lemoli, MD
Journal: Blood
Blood (2011) 118 (21): 2190.
https://doi.org/10.1182/blood.V118.21.2190.2190
Published: 2011