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Volume 133, Issue 13
March 28 2019
Issue Cover

Table of Contents

EDITORIAL

Single-cell technology meets hematology: introduction to a review series
Margaret A. Goodell,David M. Bodine
View Articletitled, Single-cell technology meets hematology: introduction to a review series

BLOOD COMMENTARIES

PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS
Null donors favor prepared immunologists
Ronald P. Taylor
View Articletitled, Null donors favor prepared immunologists
CLINICAL TRIALS AND OBSERVATIONS
Maintenance therapy for AML: are we there yet?
Clinical Trials & Observations
Andrew H. Wei
View Articletitled, Maintenance therapy for AML: are we there yet?
MYELOID NEOPLASIA
Arsenic and old FLT3
Mark Levis
View Articletitled, Arsenic and old <em>FLT3</em>
THROMBOSIS AND HEMOSTASIS
MAA868 locks factor XIa in a zymogen-like state
Jeffrey I. Weitz,Noel C. Chan
View Articletitled, MAA868 locks factor XIa in a zymogen-like state

PLENARY PAPER

PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS
Human neutrophils express low levels of FcγRIIIA, which plays a role in PMN activation
Josée Golay,Rut Valgardsdottir,Gerta Musaraj,Damiano Giupponi,Orietta Spinelli,Martino Introna

There is a Blood Commentary on this article in this issue.

View Articletitled, Human neutrophils express low levels of FcγRIIIA, which plays a role in PMN activation
Supplemental data

REVIEW SERIES

Understanding cell fate control by continuous single-cell quantification
Dirk Loeffler,Timm Schroeder
View Articletitled, Understanding cell fate control by continuous single-cell quantification
New insights into hematopoietic differentiation landscapes from single-cell RNA sequencing
Sam Watcham,Iwo Kucinski,Berthold Gottgens
View Articletitled, New insights into hematopoietic differentiation landscapes from single-cell RNA sequencing
Single-cell approaches reveal novel cellular pathways for megakaryocyte and erythroid differentiation
Bethan Psaila,Adam J. Mead
View Articletitled, Single-cell approaches reveal novel cellular pathways for megakaryocyte and erythroid differentiation
Clonal approaches to understanding the impact of mutations on hematologic disease development
Jyoti Nangalia,Emily Mitchell,Anthony R. Green
View Articletitled, Clonal approaches to understanding the impact of mutations on hematologic disease development
Dissecting CLL through high-dimensional single-cell technologies
Satyen H. Gohil,Catherine J. Wu
View Articletitled, Dissecting CLL through high-dimensional single-cell technologies

CLINICAL TRIALS AND OBSERVATIONS

Azacitidine maintenance after intensive chemotherapy improves DFS in older AML patients
Clinical Trials & Observations
Gerwin Huls,Dana A. Chitu,Violaine Havelange,Mojca Jongen-Lavrencic,Arjan A. van de Loosdrecht,Bart J. Biemond,Harm Sinnige,Beata Hodossy,Carlos Graux,Rien van Marwijk Kooy,Okke de Weerdt,Dimitri Breems,Saskia Klein,Jürgen Kuball,Dries Deeren,Wim Terpstra,Marie-Christiane Vekemans,Gert J. Ossenkoppele,Edo Vellenga,Bob Löwenberg,the Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON)

There is a Blood Commentary on this article in this issue.

View Articletitled, Azacitidine maintenance after intensive chemotherapy improves DFS in older AML patients
Supplemental data

HEMATOPOIESIS AND STEM CELLS

Endothelial protein C receptor supports hematopoietic stem cell engraftment and expansion in Mpl-deficient mice
Saskia Kohlscheen,Franziska Schenk,Marcel G. E. Rommel,Katharina Cullmann,Ute Modlich
View Articletitled, Endothelial protein C receptor supports hematopoietic stem cell engraftment and expansion in Mpl-deficient mice
Supplemental data

IMMUNOBIOLOGY AND IMMUNOTHERAPY

The HLA-B −21 dimorphism impacts on NK cell education and clinical outcome of immunotherapy in acute myeloid leukemia
Alexander Hallner,Elin Bernson,Brwa Ali Hussein,Frida Ewald Sander,Mats Brune,Johan Aurelius,Anna Martner,Kristoffer Hellstrand,Fredrik B. Thorén
View Articletitled, The HLA-B −21 dimorphism impacts on NK cell education and clinical outcome of immunotherapy in acute myeloid leukemia
Supplemental data

LYMPHOID NEOPLASIA

Autocrine LTA signaling drives NF-κB and JAK-STAT activity and myeloid gene expression in Hodgkin lymphoma
Brief Report
Linda von Hoff,Eva Kärgel,Vedran Franke,Erik McShane,Kathrin W. Schulz-Beiss,Giannino Patone,Nikolai Schleussner,Marina Kolesnichenko,Norbert Hübner,Oliver Daumke,Matthias Selbach,Altuna Akalin,Stephan Mathas,Claus Scheidereit
View Articletitled, Autocrine LTA signaling drives NF-κB and JAK-STAT activity and myeloid gene expression in Hodgkin lymphoma
Supplemental data

MYELOID NEOPLASIA

FLT3-ITD impedes retinoic acid, but not arsenic, responses in murine acute promyelocytic leukemias
Cécile Esnault,Ramy Rahmé,Kim L. Rice,Caroline Berthier,Coline Gaillard,Samuel Quentin,Anne-Lise Maubert,Scott Kogan,Hugues de Thé
View Articletitled, <em>FLT3</em>-ITD impedes retinoic acid, but not arsenic, responses in murine acute promyelocytic leukemias
Supplemental data

THROMBOSIS AND HEMOSTASIS

MAA868, a novel FXI antibody with a unique binding mode, shows durable effects on markers of anticoagulation in humans
Alexander W. Koch,Nikolaus Schiering,Samu Melkko,Stefan Ewert,Janeen Salter,Yiming Zhang,Peter McCormack,Jianying Yu,Xueming Huang,Yu-Hsin Chiu,Zhiping Chen,Simone Schleeger,Geraldine Horny,Keith DiPetrillo,Lionel Muller,Andreas Hein,Frederic Villard,Meike Scharenberg,Paul Ramage,Ulrich Hassiepen,Serge Côté,Julie DeGagne,Carsten Krantz,Jörg Eder,Brian Stoll,Kenneth Kulmatycki,David L. Feldman,Peter Hoffmann,Craig T. Basson,Robert J. A. Frost,Yasser Khder

There is a Blood Commentary on this article in this issue.

View Articletitled, MAA868, a novel FXI antibody with a unique binding mode, shows durable effects on markers of anticoagulation in humans
Supplemental data

BLOOD WORK

CAR T cells mimicking an aggressive lymphoma
Joo Y. Song,Alex F. Herrera
View Articletitled, CAR T cells mimicking an aggressive lymphoma
Acanthocytosis causing chronic hemolysis in a patient with advanced cirrhosis
Eric I. Marks,Thomas A. Ollila
View Articletitled, Acanthocytosis causing chronic hemolysis in a patient with advanced cirrhosis
All Issues

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