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Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia
Thrombotic complications in adult patients with lymphoma: a meta-analysis of 29 independent cohorts including 18 018 patients and 1149 events
Presence of the P2RY8-CRLF2 rearrangement is associated with a poor prognosis in non–high-risk precursor B-cell acute lymphoblastic leukemia in children treated according to the ALL-BFM 2000 protocol
Issue Archive
Table of Contents
INSIDE BLOOD
BLOOD WORK
PLENARY PAPERS
Duffy antigen receptor for chemokines (Darc) polymorphism regulates circulating concentrations of monocyte chemoattractant protein-1 and other inflammatory mediators
Renate B. Schnabel,Jens Baumert,Maja Barbalic,Josée Dupuis,Patrick T. Ellinor,Peter Durda,Abbas Dehghan,Joshua C. Bis,Thomas Illig,Alanna C. Morrison,Nancy S. Jenny,John F. Keaney, Jr,Christian Gieger,Cathy Tilley,Jennifer F. Yamamoto,Natalie Khuseyinova,Gerardo Heiss,Margaret Doyle,Stefan Blankenberg,Christian Herder,Jeremy D. Walston,Yanyan Zhu,Ramachandran S. Vasan,Norman Klopp,Eric Boerwinkle,Martin G. Larson,Bruce M. Psaty,Annette Peters,Christie M. Ballantyne,Jacqueline C. M. Witteman,Ron C. Hoogeveen,Emelia J. Benjamin,Wolfgang Koenig,Russell P. Tracy
HOW I TREAT
CLINICAL TRIALS AND OBSERVATIONS
Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia
Clinical Trials & Observations
Richard C. Harvey,Charles G. Mullighan,I-Ming Chen,Walker Wharton,Fady M. Mikhail,Andrew J. Carroll,Huining Kang,Wei Liu,Kevin K. Dobbin,Malcolm A. Smith,William L. Carroll,Meenakshi Devidas,W. Paul Bowman,Bruce M. Camitta,Gregory H. Reaman,Stephen P. Hunger,James R. Downing,Cheryl L. Willman
Thrombotic complications in adult patients with lymphoma: a meta-analysis of 29 independent cohorts including 18 018 patients and 1149 events
Clinical Trials & Observations
Vanesa Caruso,Augusto Di Castelnuovo,Susana Meschengieser,Maria A. Lazzari,Giovanni de Gaetano,Sergio Storti,Licia Iacoviello,Maria Benedetta Donati
GENE THERAPY
Lentiviral gene therapy of murine hematopoietic stem cells ameliorates the Pompe disease phenotype
Niek P. van Til,Merel Stok,Fatima S. F. Aerts Kaya,Monique C. de Waard,Elnaz Farahbakhshian,Trudi P. Visser,Marian A. Kroos,Edwin H. Jacobs,Monique A. Willart,Pascal van der Wegen,Bob J. Scholte,Bart N. Lambrecht,Dirk J. Duncker,Ans T. van der Ploeg,Arnold J. J. Reuser,Monique M. Verstegen,Gerard Wagemaker
HEMATOPOIESIS AND STEM CELLS
IMMUNOBIOLOGY
LYMPHOID NEOPLASIA
Elevated IL-17 produced by Th17 cells promotes myeloma cell growth and inhibits immune function in multiple myeloma
Rao H. Prabhala,Dheeraj Pelluru,Mariateresa Fulciniti,Harsha K. Prabhala,Puru Nanjappa,Weihua Song,Christine Pai,Samir Amin,Yu-Tzu Tai,Paul G. Richardson,Irene M. Ghobrial,Steven P. Treon,John F. Daley,Kenneth C. Anderson,Jeffery L. Kutok,Nikhil C. Munshi
Presence of the P2RY8-CRLF2 rearrangement is associated with a poor prognosis in non–high-risk precursor B-cell acute lymphoblastic leukemia in children treated according to the ALL-BFM 2000 protocol
Brief Report
Gunnar Cario,Martin Zimmermann,Renja Romey,Stefan Gesk,Inga Vater,Jochen Harbott,André Schrauder,Anja Moericke,Shai Izraeli,Takashi Akasaka,Martin J. S. Dyer,Reiner Siebert,Martin Schrappe,Martin Stanulla
PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS
TRANSPLANTATION
VASCULAR BIOLOGY
CORRESPONDENCE
Long-term survival after nonintensive chemotherapy in some juvenile myelomonocytic leukemia patients with CBL mutations, and the possible presence of healthy persons with the mutations
Kazuyuki Matsuda,Chiaki Taira,Kazuo Sakashita,Shoji Saito,Miyuki Tanaka-Yanagisawa,Ryu Yanagisawa,Yozo Nakazawa,Masaaki Shiohara,Keitaro Fukushima,Megumi Oda,Takayuki Honda,Tatsutoshi Nakahata,Kenichi Koike
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Cover Image
Cover Image
![issue cover]()
The cover depicts dye transfer occurring with at least some membrane dyes. At the beginning of the experiment, only the hematopoietic progenitor cells (cyan) were stained with the lipophilic dye (red), but after few hours of coculture on a layer of human umbilical vein endothelial cells (HUVECs), a significant amount of red dye fluorescence is found associated with the stromal cells. See the article by Lassailly et al on page 5347.
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