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Serum ferritin level changes in children with sickle cell disease on chronic blood transfusion are nonlinear and are associated with iron load and liver injury
Relationship of erythropoietin, fetal hemoglobin, and hydroxyurea treatment to tricuspid regurgitation velocity in children with sickle cell disease
Mutation of the H-bond acceptor S119 in the ADAMTS13 metalloprotease domain reduces secretion and substrate turnover in a patient with congenital thrombotic thrombocytopenic purpura
Issue Archive
November 19 2009
Table of Contents
INSIDE BLOOD
REVIEW ARTICLES
HOW I TREAT
CLINICAL TRIALS AND OBSERVATIONS
Serum ferritin level changes in children with sickle cell disease on chronic blood transfusion are nonlinear and are associated with iron load and liver injury
Clinical Trials & Observations
Thomas V. Adamkiewicz,Miguel R. Abboud,Carole Paley,Nancy Olivieri,Melanie Kirby-Allen,Elliott Vichinsky,James F. Casella,Ofelia A. Alvarez,Julio C. Barredo,Margaret T. Lee,Rathi V. Iyer,Abdullah Kutlar,Kathleen M. McKie,Virgil McKie,Nadine Odo,Beatrice Gee,Janet L. Kwiatkowski,Gerald M. Woods,Thomas Coates,Winfred Wang,Robert J. Adams
Relationship of erythropoietin, fetal hemoglobin, and hydroxyurea treatment to tricuspid regurgitation velocity in children with sickle cell disease
Clinical Trials & Observations
Victor R. Gordeuk,Andrew Campbell,Sohail Rana,Mehdi Nouraie,Xiaomei Niu,Caterina P. Minniti,Craig Sable,Deepika Darbari,Niti Dham,Onyinye Onyekwere,Tatiana Ammosova,Sergei Nekhai,Gregory J. Kato,Mark T. Gladwin,Oswaldo L. Castro
HEMATOPOIESIS AND STEM CELLS
The role and regulation of friend of GATA-1 (FOG-1) during blood development in the zebrafish
Julio D. Amigo,Gabriele E. Ackermann,John J. Cope,Ming Yu,Jeffrey D. Cooney,Dongdong Ma,Nathaniel B. Langer,Ebrahim Shafizadeh,George C. Shaw,Wyatt Horsely,Nikolaus S. Trede,Alan J. Davidson,Bruce A. Barut,Yi Zhou,Sarah A. Wojiski,David Traver,Tyler B. Moran,George Kourkoulis,Karl Hsu,John P. Kanki,Dhvanit I. Shah,Hui Feng Lin,Robert I. Handin,Alan B. Cantor,Barry H. Paw
IMMUNOBIOLOGY
Alternatively activated macrophages engage in homotypic and heterotypic interactions through IL-4 and polyamine-induced E-cadherin/catenin complexes
Jan Van den Bossche,Pieter Bogaert,Jolanda van Hengel,Christopher J. Guérin,Geert Berx,Kiavash Movahedi,Rafael Van den Bergh,Anna Pereira-Fernandes,Jan M. C. Geuns,Hanspeter Pircher,Pierre Dorny,Johan Grooten,Patrick De Baetselier,Jo A. Van Ginderachter
LYMPHOID NEOPLASIA
Hairy cell leukemias with unmutated IGHV genes define the minor subset refractory to single-agent cladribine and with more aggressive behavior
Francesco Forconi,Elisa Sozzi,Emanuele Cencini,Francesco Zaja,Tamara Intermesoli,Caterina Stelitano,Luigi Rigacci,Filippo Gherlinzoni,Renato Cantaffa,Anna Baraldi,Andrea Gallamini,Alfonso Zaccaria,Alessandro Pulsoni,Marco Gobbi,Maristella Tassi,Donatella Raspadori,Lorenzo Leoncini,Andrea Rinaldi,Elena Sabattini,Francesco Bertoni,Stefano A. Pileri,Francesco Lauria
TAPP2 links phosphoinositide 3-kinase signaling to B-cell adhesion through interaction with the cytoskeletal protein utrophin: expression of a novel cell adhesion-promoting complex in B-cell leukemia
Jennifer L. Costantini,Samuel M. S. Cheung,Sen Hou,Hongzhao Li,Sam K. Kung,James B. Johnston,John A. Wilkins,Spencer B. Gibson,Aaron J. Marshall
Follicular lymphoma cells induce T-cell immunologic synapse dysfunction that can be repaired with lenalidomide: implications for the tumor microenvironment and immunotherapy
Alan G. Ramsay,Andrew J. Clear,Gavin Kelly,Rewas Fatah,Janet Matthews,Finlay MacDougall,T. Andrew Lister,Abigail M. Lee,Maria Calaminici,John G. Gribben
PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS
PLATELETS AND THROMBOPOIESIS
THROMBOSIS AND HEMOSTASIS
Mutation of the H-bond acceptor S119 in the ADAMTS13 metalloprotease domain reduces secretion and substrate turnover in a patient with congenital thrombotic thrombocytopenic purpura
Brief Report
Hendrik B. Feys,Inge Pareyn,Renee Vancraenenbroeck,Marc De Maeyer,Hans Deckmyn,Chris Van Geet,Karen Vanhoorelbeke
CORRESPONDENCE
Limited role of MHC class I chain–related gene A (MICA) typing in assessing graft-versus-host disease risk after fully human leukocyte antigen–matched unrelated donor transplantation
Eric Anderson,Bartosz Grzywacz,Hongbo Wang,Tao Wang,Michael Haagenson,Stephen Spellman,Bruce R. Blazar,Jeffrey S. Miller,Michael R. Verneris
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Cover Image
Cover Image
![issue cover]()
Pictured are adult zebrafish (Danio rerio) superimposed on a background of zebrafish erythrocytes, which are nucleated like those of most vertebrates, in contrast to mammalian erythrocytes. The genetic programs for hematopoiesis and lineage differentiation are highly conserved, making zebrafish an excellent model organism for studying the genetics and developmental biology of the blood system. Here, researchers show the function of friend of GATA-1 (FOG-1) in blood lineage differentiation and its regulation by GATA-1 in the zebrafish. See the article by Amigo et al on page 4654. Artwork and photograph courtesy of Lisa Sherman and A. Joseph Dalton.
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