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Jonathan Skupsky
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Journal Articles

Effect of B-cell depletion using anti-CD20 therapy on inhibitory antibody formation to human FVIII in hemophilia A mice

Ai-Hong Zhang, Jonathan Skupsky, David W. Scott
Journal: Blood
Blood (2011) 117 (7): 2223–2226.
https://doi.org/10.1182/blood-2010-06-293324
Published: 2011
Includes: Supplemental data
Journal Articles

B-Cell Depletion Using IgG1 Anti-CD20 Spares MZ B Cells and Promotes Tolerance to Human FVIII In a Murine Model of Hemophilia A

Ai-Hong Zhang, Ph.D., Jonathan Skupsky, PhD, David W. Scott, PhD
Journal: Blood
Blood (2010) 116 (21): 2206.
https://doi.org/10.1182/blood.V116.21.2206.2206
Published: 2010
Journal Articles

Tolerance Induced by B-Cell Gene Therapy: Expansion and Increased Activity of Antigen-Specific Tregs.

Jonathan Skupsky, BS, Yan Su, Ph.D, David W. Scott, PhD
Journal: Blood
Blood (2009) 114 (22): 2129.
https://doi.org/10.1182/blood.V114.22.2129.2129
Published: 2009
Journal Articles

Effect of B-Cell Depletion On Inhibitor Antibody Formation and Immune Tolerance Induction to Human Factor VIII in Hemophilia A Mice.

Ai-Hong Allan Zhang, MS, PhD, Jonathan Skupsky, BS, David W. Scott, PhD
Journal: Blood
Blood (2009) 114 (22): 2137.
https://doi.org/10.1182/blood.V114.22.2137.2137
Published: 2009
Journal Articles

Immunogenicity of FVIII: a Role for Thrombin.

Jonathan Skupsky, BS, Ai-Hong Allan Zhang, MS, PhD, David W. Scott, PhD
Journal: Blood
Blood (2009) 114 (22): 3175.
https://doi.org/10.1182/blood.V114.22.3175.3175
Published: 2009
Journal Articles

A role for thrombin in the initiation of the immune response to therapeutic factor VIII

Jonathan Skupsky, Ai-Hong Zhang, Yan Su, David W. Scott
Journal: Blood
Blood (2009) 114 (21): 4741–4748.
https://doi.org/10.1182/blood-2008-10-186452
Published: 2009
Includes: Supplemental data
Journal Articles

Unraveling the Danger Signal Necessary for the Immune Response to Therapeutic Factor VIII.

Jonathan Skupsky, BS, Ai-Hong Zhang, MS, PhD, David W. Scott, PhD
Journal: Blood
Blood (2008) 112 (11): 1220.
https://doi.org/10.1182/blood.V112.11.1220.1220
Published: 2008
Journal Articles

Role of Adaptive Regulatory T Cells in the Induction of Tolerance to FVIII

Jonathan Skupsky, BS, Elika Farrokhi, BS, David W. Scott, PhD
Journal: Blood
Blood (2008) 112 (11): 1027.
https://doi.org/10.1182/blood.V112.11.1027.1027
Published: 2008
Journal Articles

De-Immunization of Human Factor VIII: Identification of Epitopes in the C2 Domain

Leonard Moise, Ph.D, Jonathan Skupsky, BS, Ryan Tassone, Julie A McMurry, William D Martin, Anne S. De Groot, M.D., David W. Scott, PhD
Journal: Blood
Blood (2008) 112 (11): 1030.
https://doi.org/10.1182/blood.V112.11.1030.1030
Published: 2008
Journal Articles

Immunogenicity of Factor VIII: Is Clotting the “Danger” Signal?.

Jonathan Skupsky, B.S., David W. Scott, PhD
Journal: Blood
Blood (2007) 110 (11): 2685.
https://doi.org/10.1182/blood.V110.11.2685.2685
Published: 2007
Journal Articles

Immunogenicity of Human Factor VIII in Rhesus and Cynomolgus Monkeys.

Jonathan Skupsky, BS, Jay N. Lozier, M.D., Robert E. Donahue, D.V.M., Mark N. Metzger, B.A., Agnes M. Azimzadeh, Ph.D., Richard N. Pierson, III, M.D., David W. Scott, Ph.D.
Journal: Blood
Blood (2007) 110 (11): 3148.
https://doi.org/10.1182/blood.V110.11.3148.3148
Published: 2007