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Issue Archive

Volume 8, Issue 1
January 9 2024
Issue Cover

Table of Contents

INSIDE BLOOD ADVANCES

Deciphering racial disparities in multiple myeloma outcomes
Clinical Trials & Observations
Kimberly A. Bertrand,Raphael Szalat
View Articletitled, Deciphering racial disparities in multiple myeloma outcomes
Shrinking the divide: improving myeloma CART access
Ajay K. Nooka,Monique A. Hartley-Brown,Kenneth C. Anderson,Sagar Lonial
View Articletitled, Shrinking the divide: improving myeloma CART access

REVIEW ARTICLE

Nelarabine: when and how to use in the treatment of T-cell acute lymphoblastic leukemia
Shai Shimony,Daniel J. DeAngelo,Marlise R. Luskin
View Articletitled, Nelarabine: when and how to use in the treatment of T-cell acute lymphoblastic leukemia

CLINICAL TRIALS AND OBSERVATIONS

Isoquercetin for thromboinflammation in sickle cell disease: a randomized double-blind placebo-controlled trial
Clinical Trials & Observations
Maria A. Lizarralde-Iragorri,Bindu Parachalil Gopalan,Brenda Merriweather,Jennifer Brooks,Mai Hill,Dianna Lovins,Ruth Pierre-Charles,Ann Cullinane,Alina Dulau-Florea,Duck-Yeon Lee,Rafael Villasmil,Neal Jeffries,Arun S. Shet
View Articletitled, Isoquercetin for thromboinflammation in sickle cell disease: a randomized double-blind placebo-controlled trial
Supplemental data

HEALTH SERVICES AND OUTCOMES

Implementation of hospital-based sickle cell newborn screening and follow-up programs in Haiti
Global Advances
Ofelia A. Alvarez,Nora St Victor Dély,Michele Paul Hanna,Rony Saint Fleur,Marie Cetoute,Sarah Metalonis,Tally Hustace,Eric C. Brown,Louis Herns Marcelin,Emanise Muscadin,Ronald Eveillard,Emmeline Lerebours
View Articletitled, Implementation of hospital-based sickle cell newborn screening and follow-up programs in Haiti
Supplemental data
Socioeconomic determinants of the biology and outcomes of acute lymphoblastic leukemia in adults
Hannah Johnston,Hamed Rahmani Youshanlouei,Clinton Osei,Anand A. Patel,Adam DuVall,Peng Wang,Pankhuri Wanjari,Jeremy Segal,Girish Venkataraman,Jason X. Cheng,Sandeep Gurbuxani,Angela Lager,Carrie Fitzpatrick,Michael Thirman,Mariam Nawas,Hongtao Liu,Michael Drazer,Olatoyosi Odenike,Richard Larson,Wendy Stock,Caner Saygin
View Articletitled, Socioeconomic determinants of the biology and outcomes of acute lymphoblastic leukemia in adults
Supplemental data
Comparing super-utilizers and lower-utilizers among commercial- and Medicare-insured adults with sickle cell disease
Sarah R. MacEwan,ChienWei Chiang,Sarah H. O’Brien,Susan Creary,Chyongchiou J. Lin,J. Madison Hyer,Robert M. Cronin
View Articletitled, Comparing super-utilizers and lower-utilizers among commercial- and Medicare-insured adults with sickle cell disease
Supplemental data
Racial and ethnic differences in clinical outcomes among patients with multiple myeloma treated with CAR T-cell therapy
Clinical Trials & Observations
Lauren C. Peres,Laura B. Oswald,Christen M. Dillard,Gabriel De Avila,Taiga Nishihori,Brandon J. Blue,Ciara L. Freeman,Frederick L. Locke,Melissa Alsina,Omar Castaneda Puglianini,Leyla Shune,Douglas W. Sborov,Charlotte Wagner,Danai Dima,Hamza Hashmi,James A. Davis,Mehmet H. Kocoglu,Ashraf Z. Badros,Shebli Atrash,Gary Simmons,Nilesh Kalariya,Christopher Ferreri,Larry D. Anderson, Jr,Aimaz Afrough,Gurbakhash Kaur,Yi Lin,Lawrence Liu,Omar Nadeem,Peter Voorhees,Jack Khouri,Joseph McGuirk,Surbhi Sidana,Doris K. Hansen,Krina Patel
View Articletitled, Racial and ethnic differences in clinical outcomes among patients with multiple myeloma treated with CAR T-cell therapy
Supplemental data
Shrinking the divide: improving myeloma CART access
Ajay K. Nooka,Monique A. Hartley-Brown,Kenneth C. Anderson,Sagar Lonial
View Articletitled, Shrinking the divide: improving myeloma CART access

HEMATOPOIESIS AND STEM CELLS

CD61 identifies a superior population of aged murine HSCs and is required to preserve quiescence and self-renewal
Natalia Skinder,Irene Sanz Fernández,Albertien Dethmers-Ausema,Ellen Weersing,Gerald de Haan
View Articletitled, CD61 identifies a superior population of aged murine HSCs and is required to preserve quiescence and self-renewal
Supplemental data

IMMUNOBIOLOGY AND IMMUNOTHERAPY

Teclistamab impairs humoral immunity in patients with heavily pretreated myeloma: importance of immunoglobulin supplementation
Kristine A. Frerichs,Christie P. M. Verkleij,Maria Victoria Mateos,Thomas G. Martin,Cesar Rodriguez,Ajay Nooka,Arnob Banerjee,Katherine Chastain,Alfredo Perales-Puchalt,Tara Stephenson,Clarissa Uhlar,Rachel Kobos,Bronno van der Holt,Sandy Kruyswijk,Maria T. Kuipers,Kaz Groen,Deeksha Vishwamitra,Sheri Skerget,Diana Cortes-Selva,Margaret Doyle,Hans L. Zaaijer,Sonja Zweegman,Raluca I. Verona,Niels W. C. J. van de Donk
View Articletitled, Teclistamab impairs humoral immunity in patients with heavily pretreated myeloma: importance of immunoglobulin supplementation
Supplemental data

LYMPHOID NEOPLASIA

Analysis of baseline circulating tumor cells integrated with PET/CT findings in transplant-ineligible multiple myeloma
Daisuke Ikeda,Toshiki Terao,Mitsuaki Oura,Atsushi Uehara,Rikako Tabata,Kentaro Narita,Masami Takeuchi,Youichi Machida,Kosei Matsue
View Articletitled, Analysis of baseline circulating tumor cells integrated with PET/CT findings in transplant-ineligible multiple myeloma
Supplemental data
A clinical trial of therapeutic vaccination in lymphoma with serial tumor sampling and single-cell analysis
Clinical Trials & Observations
Tanaya Shree,Sarah Haebe,Debra K. Czerwinski,Erik Eckhert,Grady Day,Anuja Sathe,Susan Grimes,Matthew J. Frank,Lauren S. Maeda,Ash A. Alizadeh,Ranjana Advani,Richard T. Hoppe,Steven R. Long,Brock Martin,Michael G. Ozawa,Michael S. Khodadoust,Hanlee P. Ji,Ronald Levy
View Articletitled, A clinical trial of therapeutic vaccination in lymphoma with serial tumor sampling and single-cell analysis
Supplemental data
Resistance to PRMT5-targeted therapy in mantle cell lymphoma
Mackenzie Elizabeth Long,Shirsha Koirala,Shelby Sloan,Fiona Brown-Burke,Christoph Weigel,Lynda Villagomez,Kara Corps,Archisha Sharma,Ian Hout,Margaret Harper,JoBeth Helmig-Mason,Sheetal Tallada,Zhengming Chen,Peggy Scherle,Kris Vaddi,Selina Chen-Kiang,Maurizio Di Liberto,Cem Meydan,Jonathan Foox,Daniel Butler,Christopher Mason,Lapo Alinari,Bradley W. Blaser,Robert Baiocchi
View Articletitled, Resistance to PRMT5-targeted therapy in mantle cell lymphoma
Supplemental data
Prevalence and impact of diabetes on survival of patients with multiple myeloma in different racial groups
Clinical Trials & Observations
Urvi A. Shah,Erin Moshier,Andriy Derkach,Yuanhui Huang,Sham Mailankody,Carlyn R. Tan,Kylee Maclachlan,Malin Hultcrantz,Neha Korde,Hani Hassoun,Santiago Thibaud,Larysa Sanchez,Cesar Rodriguez,Shambavi Richard,Joshua Richter,Adriana Rossi,Hearn Jay Cho,Alexander Lesokhin,Ajai Chari,Saad Z. Usmani,Sundar Jagannath,Samir Parekh,Emily J. Gallagher
View Articletitled, Prevalence and impact of diabetes on survival of patients with multiple myeloma in different racial groups
Supplemental data
Deciphering racial disparities in multiple myeloma outcomes
Clinical Trials & Observations
Kimberly A. Bertrand,Raphael Szalat
View Articletitled, Deciphering racial disparities in multiple myeloma outcomes

MYELOID NEOPLASIA

The nonessential amino acid cysteine is required to prevent ferroptosis in acute myeloid leukemia
Alan Cunningham,Lieve L. Oudejans,Marjan Geugien,Diego Antonio Pereira-Martins,Albertus T. J. Wierenga,Ayşegül Erdem,Dominique Sternadt,Gerwin Huls,Jan Jacob Schuringa
View Articletitled, The nonessential amino acid cysteine is required to prevent ferroptosis in acute myeloid leukemia
Supplemental data
Deep learning predicts therapy-relevant genetics in acute myeloid leukemia from Pappenheim-stained bone marrow smears
Jacqueline Kockwelp,Sebastian Thiele,Jannis Bartsch,Lars Haalck,Jörg Gromoll,Stefan Schlatt,Rita Exeler,Annalen Bleckmann,Georg Lenz,Sebastian Wolf,Björn Steffen,Wolfgang E. Berdel,Christoph Schliemann,Benjamin Risse,Linus Angenendt
View Articletitled, Deep learning predicts therapy-relevant genetics in acute myeloid leukemia from Pappenheim-stained bone marrow smears
Supplemental data
Linking GATA2 to myeloid dysplasia and complex cytogenetics in adult myelodysplastic neoplasm and acute myeloid leukemia
Daniel J. Robbins,Tatiana S. Pavletich,Apoorva T. Patil,Demetra Pahopos,Michael Lasarev,Usha S. Polaki,Zhubin J. Gahvari,Emery H. Bresnick,Daniel R. Matson
View Articletitled, Linking GATA2 to myeloid dysplasia and complex cytogenetics in adult myelodysplastic neoplasm and acute myeloid leukemia
Supplemental data
CBFA2T3::GLIS2 pediatric acute megakaryoblastic leukemia is sensitive to BCL-XL inhibition by navitoclax and DT2216
Verena Gress,Mathieu Roussy,Luc Boulianne,Mélanie Bilodeau,Sophie Cardin,Nehme El-Hachem,Véronique Lisi,Banafsheh Khakipoor,Alexandre Rouette,Azer Farah,Louis Théret,Léo Aubert,Furat Fatima,Éric Audemard,Pierre Thibault,Éric Bonneil,Jalila Chagraoui,Louise Laramée,Patrick Gendron,Loubna Jouan,Safa Jammali,Bastien Paré,Shawn M. Simpson,Thai Hoa Tran,Michel Duval,Pierre Teira,Henrique Bittencourt,Raoul Santiago,Frédéric Barabé,Guy Sauvageau,Martin A. Smith,Josée Hébert,Philippe P. Roux,Tanja A. Gruber,Vincent-Philippe Lavallée,Brian T. Wilhelm,Sonia Cellot
View Articletitled, CBFA2T3::GLIS2 pediatric acute megakaryoblastic leukemia is sensitive to BCL-X<sub>L</sub> inhibition by navitoclax and DT2216
Supplemental data

PLATELETS AND THROMBOPOIESIS

Structural analysis of platelet fragments and extracellular vesicles produced by apheresis platelets during storage
Silvia H. De Paoli,Mehulkumar Patel,Oumsalama K. Elhelu,Ivan D. Tarandovskiy,Tseday Z. Tegegn,Jan Simak
View Articletitled, Structural analysis of platelet fragments and extracellular vesicles produced by apheresis platelets during storage
Supplemental data

RED CELLS, IRON, AND ERYTHROPOIESIS

Phosphoproteomics and morphology of stored human red blood cells treated by protein tyrosine phosphatases inhibitor
Manon Bardyn,David Crettaz,Benjamin Rappaz,Romain Hamelin,Florence Armand,Jean-Daniel Tissot,Gerardo Turcatti,Michel Prudent
View Articletitled, Phosphoproteomics and morphology of stored human red blood cells treated by protein tyrosine phosphatases inhibitor
Supplemental data
Characterizing epigenetic aging in an adult sickle cell disease cohort
Brandon M. Lê,Daniel Hatch,Qing Yang,Nirmish Shah,Faith S. Luyster,Melanie E. Garrett,Paula Tanabe,Allison E. Ashley-Koch,Mitchell R. Knisely
View Articletitled, Characterizing epigenetic aging in an adult sickle cell disease cohort
Supplemental data

THROMBOSIS AND HEMOSTASIS

Management and follow-up of pregnancy-onset thrombotic thrombocytopenic purpura: the French experience
Nicolas Béranger,Paul Coppo,Vassilis Tsatsaris,Pierre Boisseau,François Provôt,Yahsou Delmas,Pascale Poullin,Karen Vanhoorelbeke,Agnès Veyradier,Bérangère S. Joly
View Articletitled, Management and follow-up of pregnancy-onset thrombotic thrombocytopenic purpura: the French experience
Supplemental data

RESEARCH LETTERS

Clinical outcomes of older and younger patients treated with loncastuximab tesirine in the LOTIS-2 clinical trial
Clinical Trials & Observations
Mehdi Hamadani,Alexander Spira,Xiaolei Zhou,Laura Liao,Lei Chen,John Radford,Weiyun Ai,Melhem Solh,Kirit M. Ardeshna,Brian Hess,Paolo F. Caimi,Anastasios Stathis,Carmelo Carlo-Stella,Juan Pablo Alderuccio,Brad Kahl,Ying Wang,Yajuan Qin,Zhiying Cindy Xu,Pier Luigi Zinzani
View Articletitled, Clinical outcomes of older and younger patients treated with loncastuximab tesirine in the LOTIS-2 clinical trial
Supplemental data
CD36 regulates factor VIII secretion from liver endothelial cells
Paula Reventun,Pablo Toledano-Sanz,Nunzio Alcharani,Maria Viskadourou,Alanna C. Morrison,Maria Sabater-Lleal,Alisa S. Wolberg,Paul S. de Vries,Nicholas L. Smith,William O. Osburn,Marios Arvanitis,Charles J. Lowenstein,the Cohorts for Heart and Aging in Genomic Epidemiology Hemostasis Working Group
View Articletitled, CD36 regulates factor VIII secretion from liver endothelial cells
Supplemental data
Impact of treatment effect on MRD and PFS: an aggregate data analysis from randomized clinical trials in multiple myeloma
Clinical Trials & Observations
Bruno Paiva,Anastasiia Zherniakova,Jorge M. Nuñez-Córdoba,Paula Rodriguez-Otero,Qian Shi,Nikhil C. Munshi,Brian G. M. Durie,Jesus San-Miguel
View Articletitled, Impact of treatment effect on MRD and PFS: an aggregate data analysis from randomized clinical trials in multiple myeloma
Supplemental data
  • Cover Image

    Cover Image

    issue cover

    In this 3-dimensional illustration of sickle cell anemia, clumps of sickle cells block the blood vessel. ID 128974418 © Kateryna Kon | Dreamstime.com

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