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Issue Archive

Volume 5, Issue 21
November 9 2021
Issue Cover

Table of Contents

STIMULUS REPORT

A novel class of ZNF384 aberrations in acute leukemia
Marketa Zaliova,Lucie Winkowska,Jan Stuchly,Karel Fiser,Petr Triska,Martina Zwyrtkova,Ondrej Hrusak,Julia Starkova,Lucie Sramkova,Jan Stary,Jan Trka,Jan Zuna
View Articletitled, A novel class of ZNF384 aberrations in acute leukemia
Supplemental data
Anti-cysteine/spacer antibodies that open ADAMTS13 are a common feature in iTTP
Laure De Waele,Alexandre Curie,Kadri Kangro,Edwige Tellier,Gilles Kaplanski,Andres Männik,Claudia Tersteeg,Bérangère S. Joly,Paul Coppo,Agnès Veyradier,Simon F. De Meyer,Elien Roose,Karen Vanhoorelbeke
View Articletitled, Anti-cysteine/spacer antibodies that open ADAMTS13 are a common feature in iTTP
Rational biomarker development for the early and minimally invasive monitoring of AML
Sherif Abdelhamed,John T. Butler,Seul Jung,Ding-Wen Chen,Gaye Jenkins,Lina Gao,Jeong Y. Lim,Jeffery M. Klco,Terzah M. Horton,Peter Kurre
View Articletitled, Rational biomarker development for the early and minimally invasive monitoring of AML
Supplemental data

SYSTEMATIC REVIEW

Heparin-induced thrombocytopenia in patients with COVID-19: a systematic review and meta-analysis
Noppacharn Uaprasert,Nuanrat Tangcheewinsirikul,Ponlapat Rojnuckarin,Rushad Patell,Jeffrey I. Zwicker,Thita Chiasakul
View Articletitled, Heparin-induced thrombocytopenia in patients with COVID-19: a systematic review and meta-analysis
Supplemental data

CLINICAL TRIALS AND OBSERVATIONS

Long-term quality of life of patients with acute promyelocytic leukemia treated with arsenic trioxide vs chemotherapy
Clinical Trials & Observations
Fabio Efficace,Uwe Platzbecker,Massimo Breccia,Francesco Cottone,Paola Carluccio,Prassede Salutari,Eros Di Bona,Erika Borlenghi,Francesco Autore,Luciano Levato,Olimpia Finizio,Valentina Mancini,Stefano D’Ardia,Richard F. Schlenk,Lorella Melillo,Monica Fumagalli,Walter Fiedler,Germana Beltrami,Nicola Stefano Fracchiolla,Massimo Bernardi,Paola Fazi,Ombretta Annibali,Karin Mayer,Maria Teresa Voso,Marco Vignetti
View Articletitled, Long-term quality of life of patients with acute promyelocytic leukemia treated with arsenic trioxide vs chemotherapy
Supplemental data
Longitudinal analysis of cardiac abnormalities in pediatric patients with sickle cell anemia and effect of hydroxyurea therapy
Clinical Trials & Observations
Arushi Dhar,Tung Ming Leung,Abena Appiah-Kubi,Dorota Gruber,Banu Aygun,Olivia Serigano,Elizabeth Mitchell
View Articletitled, Longitudinal analysis of cardiac abnormalities in pediatric patients with sickle cell anemia and effect of hydroxyurea therapy
Incidence and risk factors associated with bleeding and thrombosis following chimeric antigen receptor T-cell therapy
Clinical Trials & Observations
Andrew Johnsrud,Juliana Craig,John Baird,Jay Spiegel,Lori Muffly,James Zehnder,John Tamaresis,Robert Negrin,Laura Johnston,Sally Arai,Judith Shizuru,Robert Lowsky,Everett Meyer,Wen-Kai Weng,Parveen Shiraz,Andrew Rezvani,Theresa Latchford,Crystal Mackall,David Miklos,Matthew Frank,Surbhi Sidana
View Articletitled, Incidence and risk factors associated with bleeding and thrombosis following chimeric antigen receptor T-cell therapy
Supplemental data
Role of radiotherapy to bulky sites of advanced Hodgkin lymphoma treated with ABVD: final results of FIL HD0801 trial
Clinical Trials & Observations
Umberto Ricardi,Mario Levis,Andrea Evangelista,Daniela Maria Gioia,Gian Mauro Sacchetti,Manuel Gotti,Alessandro Re,Michela Buglione,Vincenzo Pavone,Antonio Nardella,Luca Nassi,Manuela Zanni,Paola Franzone,Giovanni Piero Frezza,Alessandro Pulsoni,Lavinia Grapulin,Armando Santoro,Luigi Rigacci,Gabriele Simontacchi,Monica Tani,Francesco Zaja,Elisabetta Abruzzese,Barbara Botto,Vittorio Ruggero Zilioli,Delia Rota-Scalabrini,Roberto Freilone,Giovannino Ciccone,Andrea Riccardo Filippi,Pier Luigi Zinzani
View Articletitled, Role of radiotherapy to bulky sites of advanced Hodgkin lymphoma treated with ABVD: final results of FIL HD0801 trial
Supplemental data

HEALTH SERVICES AND OUTCOMES

Racial and ethnic enrollment disparities and demographic reporting requirements in acute leukemia clinical trials
Clinical Trials & Observations
Andrew Hantel,Marlise R. Luskin,Jacqueline S. Garcia,Wendy Stock,Daniel J. DeAngelo,Gregory A. Abel
View Articletitled, Racial and ethnic enrollment disparities and demographic reporting requirements in acute leukemia clinical trials
Supplemental data

HEMATOPOIESIS AND STEM CELLS

R4 RGS proteins suppress engraftment of human hematopoietic stem/progenitor cells by modulating SDF-1/CXCR4 signaling
Kathy Yuen Yee Chan,Chi Zhang,Yorky Tsin Sik Wong,Xiao-Bing Zhang,Chi Chiu Wang,Wing Hei Ng,Siu Ping Fok,Patrick Ming Kuen Tang,Wei Kang,Bo Feng,Ellen Ngar Yun Poon,King Yiu Lee,Cheuk Kwong Lee,Chun Chen,Tak Yeung Leung,Margaret Heung Ling Ng,Ka Fai To,Han Wang,Hugh Simon Lam,Pak Cheung Ng,Patrick Man Pan Yuen,Karen Li,Alex Wing Kwan Leung,Chi Kong Li,Kam Tong Leung
View Articletitled, R4 RGS proteins suppress engraftment of human hematopoietic stem/progenitor cells by modulating SDF-1/CXCR4 signaling
Supplemental data
Novel population of human monocyte and osteoclast progenitors from pluripotent stem cells and peripheral blood
Sierra H. Root,Héctor L. Aguila
View Articletitled, Novel population of human monocyte and osteoclast progenitors from pluripotent stem cells and peripheral blood
Supplemental data

IMMUNOBIOLOGY AND IMMUNOTHERAPY

Cytokine-induced natural killer cell training is dependent on cellular metabolism and is defective in obesity
Nidhi Kedia-Mehta,Laura Tobin,Vanessa Zaiatz-Bittencourt,Marta M. Pisarska,Conor De Barra,Chloe Choi,Einas Elamin,Donal O’Shea,Clair M. Gardiner,David K. Finlay,Andrew E. Hogan
View Articletitled, Cytokine-induced natural killer cell training is dependent on cellular metabolism and is defective in obesity
Supplemental data

LYMPHOID NEOPLASIA

The microenvironment of DLBCL is characterized by noncanonical macrophages recruited by tumor-derived CCL5
Benoît Manfroi,Maria De Grandis,Jérôme Moreaux,Sébastien Tabruyn,Jean-François Mayol,Mélanie Quintero,Christian Righini,Nathalie Sturm,Michel Aurrand-Lions,Bertrand Huard
View Articletitled, The microenvironment of DLBCL is characterized by noncanonical macrophages recruited by tumor-derived CCL5
Supplemental data
Poor neutralizing antibody responses in 106 patients with WM after vaccination against SARS-CoV-2: a prospective study
Clinical Trials & Observations
Maria Gavriatopoulou,Evangelos Terpos,Ioannis Ntanasis-Stathopoulos,Alexandros Briasoulis,Sentiljana Gumeni,Panagiotis Malandrakis,Despina Fotiou,Magdalini Migkou,Foteini Theodorakakou,Evangelos Eleutherakis-Papaiakovou,Nikolaos Kanellias,Efstathios Kastritis,Ioannis P. Trougakos,Meletios A. Dimopoulos
View Articletitled, Poor neutralizing antibody responses in 106 patients with WM after vaccination against SARS-CoV-2: a prospective study

MYELOID NEOPLASIA

A geno-clinical decision model for the diagnosis of myelodysplastic syndromes
Clinical Trials & Observations
Nathan Radakovich,Manja Meggendorfer,Luca Malcovati,C. Beau Hilton,Mikkael A. Sekeres,Jacob Shreve,Yazan Rouphail,Wencke Walter,Stephan Hutter,Anna Galli,Sara Pozzi,Chiara Elena,Eric Padron,Michael R. Savona,Aaron T. Gerds,Sudipto Mukherjee,Yasunobu Nagata,Rami S. Komrokji,Babal K. Jha,Claudia Haferlach,Jaroslaw P. Maciejewski,Torsten Haferlach,Aziz Nazha
View Articletitled, A geno-clinical decision model for the diagnosis of myelodysplastic syndromes
Supplemental data
Calcitonin receptor‐like (CALCRL) is a marker of stemness and an independent predictor of outcome in pediatric AML
Clinical Trials & Observations
Linus Angenendt,Marius Wöste,Jan-Henrik Mikesch,Maria Francisca Arteaga,Adrian Angenendt,Sarah Sandmann,Wolfgang E. Berdel,Georg Lenz,Martin Dugas,Soheil Meshinchi,Christoph Schliemann,Claudia Rössig
View Articletitled, Calcitonin receptor‐like (CALCRL) is a marker of stemness and an independent predictor of outcome in pediatric AML
Supplemental data
Mutational patterns and their correlation to CHIP-related mutations and age in hematological malignancies
Anna Stengel,Constance Baer,Wencke Walter,Manja Meggendorfer,Wolfgang Kern,Torsten Haferlach,Claudia Haferlach
View Articletitled, Mutational patterns and their correlation to CHIP-related mutations and age in hematological malignancies
Supplemental data

TRANSPLANTATION

The impact of pulmonary function in patients undergoing autologous stem cell transplantation
Clinical Trials & Observations
Jesús Duque-Afonso,Sophie Ewald,Gabriele Ihorst,Miguel Waterhouse,Tim Struessmann,Robert Zeiser,Ralph Wäsch,Hartmut Bertz,Joachim Müller-Quernheim,Justus Duyster,Jürgen Finke,Reinhard Marks,Monika Engelhardt
View Articletitled, The impact of pulmonary function in patients undergoing autologous stem cell transplantation
Supplemental data
Genetic variants associated with inflammatory bowel disease and gut graft-versus-host disease
Clinical Trials & Observations
Paul J. Martin,Barry E. Storer,David M. Levine,John A. Hansen
View Articletitled, Genetic variants associated with inflammatory bowel disease and gut graft-versus-host disease
Supplemental data
Clonal expansion of CD8+ T cells reflects graft-versus-leukemia activity and precedes durable remission following DLI
Clinical Trials & Observations
Christian R. Schultze-Florey,Leonie Kuhlmann,Solaiman Raha,Joana Barros-Martins,Ivan Odak,Likai Tan,Yankai Xiao,Sarina Ravens,Lothar Hambach,Letizia Venturini,Michael Stadler,Matthias Eder,Felicitas Thol,Michael Heuser,Reinhold Förster,Arnold Ganser,Immo Prinz,Christian Koenecke
View Articletitled, Clonal expansion of CD8<sup>+</sup> T cells reflects graft-versus-leukemia activity and precedes durable remission following DLI
Supplemental data

RESEARCH LETTER

DNA vs cDNA FLT3-ITD allelic ratio and length measurements in adult acute myeloid leukemia
Clinical Trials & Observations
David G. J. Cucchi,Christian M. Vonk,Melissa Rijken,François G. Kavelaars,Pauline A. Merle,Elvira Verhoef,Bianca Venniker-Punt,Zinia J. Kwidama,Patrycja Gradowska,Bob Löwenberg,Jeroen J. W. M. Janssen,Jacqueline Cloos,Peter J. M. Valk
View Articletitled, DNA vs cDNA <em>FLT3</em>-ITD allelic ratio and length measurements in adult acute myeloid leukemia
Supplemental data
Letermovir prophylaxis in T-cell–depleted transplants: breakthrough and rebound infections in the postmarketing setting
Maria A. V. Marzolini,Varun Mehra,Kirsty J. Thomson,Eleni Tholouli,Adrian J. C. Bloor,Anne Parker,Richard Lovell,Kim Orchard,Amy Publicover,Emma Nicholson,John A. Snowden,Jennifer Byrne,Anjum Khan,Maria H. Gilleece,Gerardo Errico,Sara Lozano,Erin Hurst,Nick Duncan,Jennifer Pirrie,Philip Crea,Ben Carpenter,Antonio Pagliuca,Karl S. Peggs
View Articletitled, Letermovir prophylaxis in T-cell–depleted transplants: breakthrough and rebound infections in the postmarketing setting

COMMENTARY

The RBC’s road to ghost and removal: splenic clearance
Robert J. Asaro,Pedro Cabrales
View Articletitled, The RBC’s road to ghost and removal: splenic clearance
  • Cover Image

    Cover Image

    issue cover

    Fluorescence microscopy of human lymphoid tissue (tonsil) stained for macrophages (CD68, green) and for hematopoietic lineage-restricted antigen (CD45, red). Lack of CD45 expression by tingible body macrophages suggests a tissue-resident origin for these cells, while tumor-associated macrophages from patients with diffuse large B-cell lymphoma are from hematopoietic origin and recruited through tumor-derived CCL5. See the article by Manfroi et al.

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Subsequent malignant neoplasms in patients previously treated with anti-CD19 CAR T-cell therapy
Phillips NS, Mulrooney DA, Williams AM, et al. Neurocognitive impairment associated with chronic morbidity in long-term survivors of Hodgkin Lymphoma. Blood Adv. 2023;7(23):7270-7278.
Unleashed monocytic engagement in Sézary syndrome during the combination of anti-CCR4 antibody with type I interferon
A multicenter study of venetoclax-based treatment for patients with Richter transformation of chronic lymphocytic leukemia
Race and ethnicity reporting and representation in hemophilia clinical trials

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