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Journal Articles

Dimethyl fumarate induces ferroptosis and impairs NF-κB/STAT3 signaling in DLBCL

Blood (2021) 138 (10): 871–884.

https://doi.org/10.1182/blood.2020009404

Published: 2021

Includes: Supplemental data

Journal Articles

Tracing the roots of CLPD-NK by TET2 and STAT3

Marco Herling, Till Braun

Blood (2021) 137 (23): 3156–3158.

https://doi.org/10.1182/blood.2020010542

Published: 2021

Journal Articles

Linking the KIR phenotype with STAT3 and TET2 mutations to identify chronic lymphoproliferative disorders of NK cells

Cédric Pastoret, Fabienne Desmots, Gaëlle Drillet, Simon Le Gallou, Marie-Laure Boulland, Alexia Thannberger, Anne-Violaine Doncker, Véronique Salaun, Gandhi Laurent Damaj, Richard Veyrat-Masson, Olivier Tournilhac, Aline Moignet, Céline Pangault, Mikaël Roussel, Thierry Fest, Thierry Lamy

Blood (2021) 137 (23): 3237–3250.

https://doi.org/10.1182/blood.2020006721

Published: 2021

Includes: Supplemental data

Journal Articles

TLR8 gain of function: a tall surprise

Bertrand Boisson, Jean-Laurent Casanova

Blood (2021) 137 (18): 2420–2422.

https://doi.org/10.1182/blood.2020010463

Published: 2021

Journal Articles

Halting the FGF/FGFR axis leads to antitumor activity in Waldenström macroglobulinemia by silencing MYD88

Blood (2021) 137 (18): 2495–2508.

https://doi.org/10.1182/blood.2020008414

Published: 2021

Includes: Supplemental data

Journal Articles

MDH1-mediated malate-aspartate NADH shuttle maintains the activity levels of fetal liver hematopoietic stem cells

Blood (2020) 136 (5): 553–571.

https://doi.org/10.1182/blood.2019003940

Published: 2020

Includes: Multimedia, Supplemental data

Journal Articles

The role of AGK in thrombocytopoiesis and possible therapeutic strategies

Haojie Jiang, Zhuo Yu, Nan Ding, Mina Yang, Lin Zhang, Xuemei Fan, Yuan Zhou, Qiang Zou, Jian Hou, Junke Zheng, Lei Zhang, Yanyan Xu, Junling Liu

Blood (2020) 136 (1): 119–129.

https://doi.org/10.1182/blood.2019003851

Published: 2020

Includes: Supplemental data

Journal Articles

Ruxolitinib can cause weight gain by blocking leptin signaling in the brain via JAK2/STAT3

Nicole Mollé, Spencer Krichevsky, Pouneh Kermani, Richard T. Silver, Ellen Ritchie, Joseph M. Scandura

Blood (2020) 135 (13): 1062–1066.

https://doi.org/10.1182/blood.2019003050

Published: 2020

Includes: Supplemental data

Journal Articles

Gene alterations in epigenetic modifiers and JAK-STAT signaling are frequent in breast implant–associated ALCL

Blood (2020) 135 (5): 360–370.

https://doi.org/10.1182/blood.2019001904

Published: 2020

Includes: Supplemental data

Journal Articles

Stat3 Is Activated By ROS to Uniquely Regulate Primitive Erythropoiesis

Zachary C. Murphy, PhD, Kathleen E. McGrath, PhD, James Palis, MD

Blood (2019) 134 (Supplement_1): 2216.

https://doi.org/10.1182/blood-2019-127229

Published: 2019

Journal Articles

Brefeldin Α Reduces STAT3 Dependent Survival of Acute Leukemia and Neuroblastoma Cells

Mitsuteru Hiwatari, MD PhD, Kentaro Watanabe, MD, Yasuo Kubota, MD, Masahiro Sekiguchi, MD, Junko Takita, MD PhD

Blood (2019) 134 (Supplement_1): 5762.

https://doi.org/10.1182/blood-2019-130056

Published: 2019

Journal Articles

A Phase I-II Study of Ruxolitinib (INCB18424) for Patients with Chronic Myeloid Leukemia with Minimal Residual Disease While on Therapy with Imatinib

Veronica A Guerra, MD, Hagop M. Kantarjian, MD, Gautam M. Borthakur, MD, Srdan Verstovsek, MD PhD, Allison Pike, RN, Farhad Ravandi, MD, Elias Jabbour, MD, Jorge E. Cortes, MD

Blood (2019) 134 (Supplement_1): 5906.

https://doi.org/10.1182/blood-2019-127272

Published: 2019

Journal Articles

Prospective, Multicentric Phase II Randomized Trial Comparing the Efficacy of Methotrexate or Cyclophosphamide in Large Granular Lymphocytic Leukemia: A French National Study. Report on the Interim Analysis

Blood (2019) 134 (Supplement_1): 1545.

https://doi.org/10.1182/blood-2019-123439

Published: 2019

Journal Articles

HTLV-1 Dysregulates IL-6 and IL-10-JAK/STAT Signaling and Induces Leukemia/Lymphoma of Mature CD4+ T Cells with Regulatory T-Cell-like Signatures

Yusuke Higuchi, MD, Jun-ichirou Yasunaga, MD PhD, Yu Mitagami, PhD, Koichi Ohshima, MD PhD, Masao Matsuoka, MD PhD

Blood (2019) 134 (Supplement_1): 1516.

https://doi.org/10.1182/blood-2019-125546

Published: 2019

Journal Articles

R4 Rgs Subfamily Proteins Suppress Engraftment and Regulate SDF-1/CXCR4 Signaling in Human CD34+ Hematopoietic Stem/Progenitor Cells

Kathy Chan, PhD, Tsin Sik Wong, Mphil, Karen Li, PhD, Xiao-Bing Zhang, PhD, Ronald Wang, PhD, King Yiu Lee, PhD, Frankie Wai Tsoi Cheng, MD, Chi Kong Li, MBBS,MD, Kam Tong Leung, PhD

Blood (2019) 134 (Supplement_1): 1927.

https://doi.org/10.1182/blood-2019-129498

Published: 2019

Journal Articles

Targeted Marrow Radiation (TMI) Improves Therapeutic Efficacy of STAT3 Decoy Molecules By Augmenting Its Delivery and Immune Modulation in an AML Mouse Model

Srideshikan Sargur Madabushi, PhD, Darren Zuro, Yu-Lin SU, PhD, Paresh Vishwasrao, MSc, Jamison Brooks, B.S, Liliana E Parra, James F Sanchez, PhD, Jeffrey Wong, MD, Marcin Kortylewski, PhD, Susanta Hui, PhD, DABR.

Blood (2019) 134 (Supplement_1): 3929.

https://doi.org/10.1182/blood-2019-127470

Published: 2019

Journal Articles

Mutated MYD88 Regulates HCK Pro-Survival Signaling through JunB in MYD88 Mutated B-Lymphoma Cells

Xia Liu, MD, Jiaji G Chen, Manit Munshi, MS, Lian Xu, MS, Amanda Kofides, Nicholas Tsakmaklis, Maria Demos, Maria Luisa Guerrera, MD, Gloria G Chan, MS, Cristina Jimenez, PhD, Zachary R Hunter, PhD, Christopher Patterson, Kirsten Meid, MPH, Andrew Keezer, BS, Jorge J. Castillo, MD, Steven P Treon, MD PhD FRCP, Guang Yang, PhD

Blood (2019) 134 (Supplement_1): 3778.

https://doi.org/10.1182/blood-2019-130885

Published: 2019

Journal Articles

Synergistic Targeting of BTK and E-Selectin/CXCR4 in the Microenvironment of Mantle Cell Lymphomas

Mahesh Basyal, Weiguo Zhang, MD PhD, Nalini B Patel, Sujan Piya, PhD, Hongying Zhang, MD PhD, William E. Fogler, PhD, William G Rice, PhD, John L. Magnani, PhD, Gautam M. Borthakur, MD, Michael Andreeff, MD PhD

Blood (2019) 134 (Supplement_1): 3802.

https://doi.org/10.1182/blood-2019-126030

Published: 2019

Journal Articles

Small Molecule-Induced, Selective STAT3 Degradation Leads to Anti-Tumor Activity in STAT3-Dependent Heme Malignancies

Fred Csibi, Nan Ji, PhD, Bin Yang, Karen Yuan, Michele Mayo, Haojing Rong, PhD, Scott Rusin, Kirti Sharma, Christine Loh, PhD, Henry Li, PhD, Sharon Townson, Jesse Chen, PhD, Hari Kamadurai, PhD, Duncan Walker, PhD, Jared Gollob, PhD MD, Nello Mainolfi, PhD

Blood (2019) 134 (Supplement_1): 3803.

https://doi.org/10.1182/blood-2019-128981

Published: 2019

Journal Articles

Inflammatory Cytokine Responsive Enzymatic Mutagenesis Fuels Myeloproliferative Neoplasm Pre-Leukemia Stem Cell Evolution

Catriona Jamieson, MD PhD, Qingfei Jiang, PhD, Frida Holm, PhD, Jane Isquith, MS, Adam Mark, Cayla Mason, BS, Wenxue Ma, MD PhD, Raymond H Diep, Jessica Pham, B.S., Eduardo Reynoso Moreno, PhD, Chanond A Nasamran, Xu Guorong, Amanda Birmingham, Leslie A Crews, PhD, Ludmil Alexandrov, Gabriel Pineda, PhD, Thomas Whisenant, Kathleen M Fisch

Blood (2019) 134 (Supplement_1): 3780.

https://doi.org/10.1182/blood-2019-131510

Published: 2019

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Dimethyl fumarate induces ferroptosis and impairs NF-κB/STAT3 signaling in DLBCL

Tracing the roots of CLPD-NK by TET2 and STAT3

Linking the KIR phenotype with STAT3 and TET2 mutations to identify chronic lymphoproliferative disorders of NK cells

TLR8 gain of function: a tall surprise

Halting the FGF/FGFR axis leads to antitumor activity in Waldenström macroglobulinemia by silencing MYD88

MDH1-mediated malate-aspartate NADH shuttle maintains the activity levels of fetal liver hematopoietic stem cells

The role of AGK in thrombocytopoiesis and possible therapeutic strategies

Ruxolitinib can cause weight gain by blocking leptin signaling in the brain via JAK2/STAT3

Gene alterations in epigenetic modifiers and JAK-STAT signaling are frequent in breast implant–associated ALCL

Stat3 Is Activated By ROS to Uniquely Regulate Primitive Erythropoiesis

Brefeldin Α Reduces STAT3 Dependent Survival of Acute Leukemia and Neuroblastoma Cells

A Phase I-II Study of Ruxolitinib (INCB18424) for Patients with Chronic Myeloid Leukemia with Minimal Residual Disease While on Therapy with Imatinib

Prospective, Multicentric Phase II Randomized Trial Comparing the Efficacy of Methotrexate or Cyclophosphamide in Large Granular Lymphocytic Leukemia: A French National Study. Report on the Interim Analysis

HTLV-1 Dysregulates IL-6 and IL-10-JAK/STAT Signaling and Induces Leukemia/Lymphoma of Mature CD4+ T Cells with Regulatory T-Cell-like Signatures

R4 Rgs Subfamily Proteins Suppress Engraftment and Regulate SDF-1/CXCR4 Signaling in Human CD34+ Hematopoietic Stem/Progenitor Cells

Targeted Marrow Radiation (TMI) Improves Therapeutic Efficacy of STAT3 Decoy Molecules By Augmenting Its Delivery and Immune Modulation in an AML Mouse Model

Mutated MYD88 Regulates HCK Pro-Survival Signaling through JunB in MYD88 Mutated B-Lymphoma Cells

Synergistic Targeting of BTK and E-Selectin/CXCR4 in the Microenvironment of Mantle Cell Lymphomas

Small Molecule-Induced, Selective STAT3 Degradation Leads to Anti-Tumor Activity in STAT3-Dependent Heme Malignancies

Inflammatory Cytokine Responsive Enzymatic Mutagenesis Fuels Myeloproliferative Neoplasm Pre-Leukemia Stem Cell Evolution

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