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Journal Articles

Diamond-Blackfan anemia

Lydie Da Costa, Thierry Leblanc, Narla Mohandas
Journal: Blood
Blood (2020) 136 (11): 1262–1273.
https://doi.org/10.1182/blood.2019000947
Published: 2020
Journal Articles

A master erythroid regulator gets its own GPS

Lily Jun-shen Huang, James J. Bieker
Journal: Blood
Blood (2020) 135 (25): 2209–2210.
https://doi.org/10.1182/blood.2020005882
Published: 2020
Journal Articles

“HIT”ing back against NETs

Shadi Swaidani, Keith R. McCrae
Journal: Blood
Blood (2020) 135 (10): 706–707.
https://doi.org/10.1182/blood.2019004461
Published: 2020
Journal Articles

A KLF4-DYRK2–mediated pathway regulating self-renewal in CML stem cells

Chun Shik Park, Andrew H. Lewis, Taylor J. Chen, Cory S. Bridges, Ye Shen, Koramit Suppipat, Monica Puppi, Julie A. Tomolonis, Paul D. Pang, Toni-Ann Mistretta, Leyuan Ma, Michael R. Green, Rachel Rau, H. Daniel Lacorazza
Journal: Blood
Blood (2019) 134 (22): 1960–1972.
https://doi.org/10.1182/blood.2018875922
Published: 2019
Includes: Supplemental data
Journal Articles

Mechanisms of Tolerance Induction through T Regulatory Cells during Chemotherapy-Mediated Immunogenic Cell Death in Acute Myeloid Leukemia

Darina Ocadlikova, PhD, Serenella Casella, Ines Pintao, Elena Adinolfi, Sabina Sangaletti, PhD, Elena De Marchi, Anna Pegoraro, Elisa Orioli, Mario Paolo Colombo, Francesco Di Virgilio, Michele Cavo, Antonio Curti, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2332.
https://doi.org/10.1182/blood-2019-126478
Published: 2019
Journal Articles

Long Term Nomacopan Administration Results in Complete Transfusion Independence in Previously Transfusion-Dependent PNH Patients

Austin Kulasekararaj, MBBS MDMRCP FRCPath, Wynne Weston-Davies, Tadeusz Robak, MD, Miles Nunn, PhD, Agnieszka Piekarska, MD, Anna Szmigielska-Kaplon, MD, Anita Hill, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4797.
https://doi.org/10.1182/blood-2019-125263
Published: 2019
Journal Articles

Direct Phosphorylation and Stabilization of MYC By Aurora B Kinase Promotes T Cell Leukemogenesis

Hudan Liu, PhD, Jue Jiang, PhD, Jingchao Wang, PhD, Ming Yue, PhD, Hui Feng, MD PhD, Guoliang Qing, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 732.
https://doi.org/10.1182/blood-2019-130112
Published: 2019
Journal Articles

TRIP13 Modulates Protein Deubiquitination to Promote Myeloma Progression

Can Li, MD, Reinaldo Franqui-Machin, Jiliang Xia, PhD, Gregory S. Thomas, Yogesh Jethava, MBBS,MDFRCPath,MRCP, Fangping Chen, MD PhD, Ivana Frech, DSc, PhD MBA, Guido J. Tricot, MD PhD, Fenghuang Zhan, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 854.
https://doi.org/10.1182/blood-2019-123818
Published: 2019
Journal Articles

Selective Targeting of Histone Deacetylase 11 Disables Metabolism of Myeloproliferative Neoplasms

Vasundhara Sharma, PhD, Lanzhu Yue, MD, Nathan P. Horvat, MDCandidate, Agni Christodoulidou, PhD, Afua Adutwumwa Akuffo, PhDCandidate, Mathew Beatty, PhD, Cem Murdun, MS, Julia Billington, PhDCandidate, William E Goodheart, MS, PhDCandidate, Eva Sahakian, PhD, Ling Zhang, MD, John J. Powers, BS, Narmin E. Amin, Que T. Lambert-Showers, Lancia Darville, PhD, Javier Pinilla Ibarz, MD PhD, Gary W. Reuther, Jennifer Lee, PhD, Xiaozhang Zheng, PhD, Pui Yee Ng, PhD, Mathew W. Martin, PhD, Gary C. Marshall, PhD, John M. Koomen, PhD, Ross L. Levine, MD, Amit Verma, MBBS, H. Leighton Grimes, PhD, Eduardo Sotomayor, MD, Zonghong Shao, MD, Kenneth Wright, PhD, Pearlie K. Epling-Burnette
Journal: Blood
Blood (2019) 134 (Supplement_1): 474.
https://doi.org/10.1182/blood-2019-127235
Published: 2019
Journal Articles

Updated Results from the German Mpnsg-0212 Combination Trial: Ruxolitinib Plus Pomalidomide in Myelofibrosis with Anemia

Frank Stegelmann, MD, Steffen Koschmieder, Susanne Isfort, Andreas Hochhaus, MD, Florian H. Heidel, Holger Hebart, Markus Bangerter, Denise Wolleschak, Christoph Scheid, MD, Joachim R Göthert, PD, MD, Philippe Schafhausen, Thomas Kindler, MD, Markus P. Radsak, MD, Robert Möhle, MD, Cornelius Waller, Nikolas von Bubnoff, Andreas Reiter, Hartmut Döhner, MD, Martin Griesshammer, MD, Konstanze Döhner
Journal: Blood
Blood (2019) 134 (Supplement_1): 672.
https://doi.org/10.1182/blood-2019-127859
Published: 2019
Journal Articles

Azacitidine for Pre-Emptive Treatment of Measurable-Residual Disease in MDS/AML Patients at High Risk of Hematological Relapse: Results of the Second Cohort of the RELAZA2 Trial

Uwe Platzbecker, MD, Jan Moritz Middeke, MD, Katja Sockel, MD, Regina Herbst, MD, Lars R. Fransecky, MD, Dominik Wolf, MD, Schumacher Martin, MD, Alwin Krämer, MD, Richard Noppeney, MD, Juergen Novotny, MD, Gesine Bug, Katharina Götze, Karsten Spiekermann, MD, Matthias Stelljes, MD, Christoph Groth, MD, Marion Subklewe, MD, Antje Schubert, Anke Mütherig, MD, Tilmann Bochtler, MD, Marika Mende, MD, Anne Sophie Kubasch, MD, Mathias Hänel, MD, Ulrich Dührsen, Prof, MD PhD, Johannes Schetelig, MD MSc, Christoph Röllig, MD MSC, Claudia D Baldus, Gerhard Ehninger, MD, Carsten Müller-Tidow, MD, Hubert Serve, MD, Michael Kramer, M.Sc., Martin Bornhäuser, MD, Christian Thiede, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 644.
https://doi.org/10.1182/blood-2019-129926
Published: 2019
Journal Articles

Phase 2 Results of APR-246 and Azacitidine (AZA) in Patients with TP53 mutant Myelodysplastic Syndromes (MDS) and Oligoblastic Acute Myeloid Leukemia (AML)

David A Sallman, MD, Amy E. DeZern, MD, Guillermo Garcia-Manero, MD, David P. Steensma, MD, Gail J. Roboz, MD, Mikkael A. Sekeres, MD MS, Thomas Cluzeau, MD PhD, Kendra L. Sweet, MD, Amy F McLemore, M.S., Kathy McGraw, PhD, John Puskas, PhD, Ling Zhang, MD, Jiqiang Yao, PhD, Qianxing Mo, PhD, Lisa Nardelli, Najla Al Ali, M.Sc, Eric Padron, MD, Greg Korbel, PhD MBA, Eyal C. Attar, MD, Hagop M. Kantarjian, MD, Jeffrey E. Lancet, MD, Pierre Fenaux, MD PhD, Alan F. List, MD, Rami S. Komrokji, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 676.
https://doi.org/10.1182/blood-2019-131055
Published: 2019
Journal Articles

KMT2A-Rearranged Infant Acute Lymphoblastic Leukemia Cells Undergo ER-Stress-Induced Apoptosis Following Exposure to Proteasome Inhibitors

Wonil Kim, PhD, Cary S. Koss, BS, Tanja A. Gruber, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1283.
https://doi.org/10.1182/blood-2019-127699
Published: 2019
Journal Articles

Improved Anti-Leukemic Pre-Clinical Efficacy of a Protac Based MDM2 Degrader in a Large AML Cohort

Malathi Kandarpa, PhD, Luke F. Peterson, PhD, Harish Potu, PhD, Megha Ramappan, Yihong Liu, Avery Polk, Shaomeng Wang, PhD, Moshe Talpaz, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2670.
https://doi.org/10.1182/blood-2019-131949
Published: 2019
Journal Articles

NPM-ALK Upregulates Jab1/Csn5 through STAT3 Activation in Anaplastic Large Cell Lymphoma: A Novel Function of NPM-ALK That Contributes to PD1/PD-L1 Immune Checkpoint Regulation

Elias Drakos, MD PhD Prof., Konstantina Stathopoulou, MSc., Lingxiao Li, PhD, Daniel Bilbao, Vasiliki Leventaki, Pedro Farrajota Neves Da Silva, MD, Vasileios Atsaves, PhD, Anders Österborg, MD PhD, L. Jeffrey Medeiros, MD, Francisco Vega, MD PhD, Jonathan H. Schatz, MD, Francois Claret, PhD, George Z. Rassidakis, MD PhD Prof.
Journal: Blood
Blood (2019) 134 (Supplement_1): 2796.
https://doi.org/10.1182/blood-2019-130457
Published: 2019
Journal Articles

New Paradigms for the Mechanisms of Thrombopoietin Receptor Activation and Dysregulation By the JAK2 V617F Mutation

Stephan Wilmes, PhD, Maximillian Hafer, BSc, Tess A Stanly, Ignacio Moraga, PhD, Joni Vuorio, PhD, Chetan Poojari, PhD, Vivek Sharma, PhD, Sara Löchte, PhD, Katiuska Pulgar Prieto, BSc, Julie A Tucker, PhD, Stevan R Hubbard, PhD, K.Christopher Garcia, PhD, Ilpo Vattulainen, PhD, Ian Hitchcock, PhD, Jacob Piehler, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2962.
https://doi.org/10.1182/blood-2019-129234
Published: 2019
Journal Articles

Molecular Mechanisms of Primary Resistance to Azacitidine in MDS/AML Patients - Data of the Hellenic MDS Study Group

Vassiliki Mpakou, PhD, Aris Spathis, PhD, Anthi Bouhla, MD, Frieda Kontsioti, PhD, Zoi Tsakiraki, MD, Sotirios Papageorgiou, MD PhD, Efthimia Mpazani, MD, Irene Glezou, MD, Konstantinos Gkodopoulos, MD, Georgia Stavroulaki, MD, Athanasios Galanopoulos, MD PhD, Argiris Symeonidis, MD PhD, Nora-Athina Viniou, MD PhD, Kalliopi Zafeiropoulou, Ioannis Kotsianidis, MD PhD, Periklis Foukas, MD PhD, Vassiliki Pappa, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5403.
https://doi.org/10.1182/blood-2019-122424
Published: 2019
Journal Articles

Fecal Microbiota Transplantation As a Treatment of Severe Steroid-Resistant Acute and Chronic Graft Versus Host Disease. Spectrum of Responses and Complications

Jaroslaw Bilinski, MD PhD, Karol Lis, MD, Agnieszka Tomaszewska, MD PhD, Pawel Grzesiowski, MD PhD, Aleksandra Pechcinska, Tomasz Dzieciatkowski, Kazimierz Halaburda, MD PhD, Magdalena Tormanowska, MD PhD, Martyna Tyszka, MD, Krzysztof Mądry, MD PhD, Ewa Karakulska-Prystupiuk, MD PhD, Alicja Hoffman, Wieslaw W. Jedrzejczak, MD PhD, Grzegorz W Basak, MD PhD Professor
Journal: Blood
Blood (2019) 134 (Supplement_1): 5667.
https://doi.org/10.1182/blood-2019-127063
Published: 2019
Journal Articles

Post Allograft Rituximab Responsive Cytopenia (RRC)

Samar Kulkarni, MD, John Murray, RGN, MSc, David Kaye, MSc, Michael Dennis, FRCPath, Anna Castleton, FRCPath, Mohd K Mamat, MRCP, James Cavet, Daniel Wiseman, FRCPath, Tim Somervaille, FRCPath, Sven Sommerfeld, MRCP, Richard Chasty, FRCPath, Adrian Bloor, FRCPath
Journal: Blood
Blood (2019) 134 (Supplement_1): 5645.
https://doi.org/10.1182/blood-2019-132214
Published: 2019
Journal Articles

Identification of Deubiquitinase OTUD1 As a Novel Player in Resistance of Multiple Myeloma to Bortezomib

Alexander Vdovin, Tomas Jelinek, MD, Matous Hrdinka, PhD, Juli R. Bago, PhD, Tereza Sevcikova, Roman Hajek, Prof, MD PhD, Michal Simicek, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5526.
https://doi.org/10.1182/blood-2019-127930
Published: 2019