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Journal Articles

A KLF4-DYRK2–mediated pathway regulating self-renewal in CML stem cells

Chun Shik Park, Andrew H. Lewis, Taylor J. Chen, Cory S. Bridges, Ye Shen, Koramit Suppipat, Monica Puppi, Julie A. Tomolonis, Paul D. Pang, Toni-Ann Mistretta, Leyuan Ma, Michael R. Green, Rachel Rau, H. Daniel Lacorazza

Blood (2019) 134 (22): 1960–1972.

https://doi.org/10.1182/blood.2018875922

Published: 2019

Includes: Supplemental data

Journal Articles

Vitamin K3 (menadione) Induces Cytotoxicity in Chronic Myeloid Leukemia Stem Cells By Upregulating DYRK2 through the Inhibition of SIAH2 Ubiquitin Ligase

Chun Shik Park, PhD, Ye Shen, PhD, Andrew H Lewis, BS, Koramit Suppipat, MD, Monica Puppi, Julie Tomolonis, Taylor J Chen, Paul Pang, Toni-Ann Mistretta, Leyuan Ma, Michael R Green, PhD, Rachel E. Rau, MD, H. Daniel Lacorazza, PhD

Blood (2017) 130 (Supplement 1): 4171.

https://doi.org/10.1182/blood.V130.Suppl_1.4171.4171

Published: 2017

Journal Articles

DYRK2 Inhibits the Self-Renewal of Leukemic Stem Cells in Chronic Myeloid Leukemia By Inducing Degradation of c-Myc Downstream of the Reprogramming Factor KLF4

Chun Shik Park, PhD, Ye Shen, BS, Koramit Suppipat, MD, Andrew Lewis, B.S., Julie Tomolonis, B.S., Monica Puppi, M.Sc., toni-Ann Mistretta, PhD, Leyuan Ma, Michael R Green, MD PhD, Daniel Lacorazza, PhD

Blood (2016) 128 (22): 1879.

https://doi.org/10.1182/blood.V128.22.1879.1879

Published: 2016

Journal Articles

Krüppel-like Factor 4 (KLF4) Suppresses T-Cell Acute Lymphoblastic Leukemia By Inhibiting Expression of MAP2K7 and Expansion of Leukemia Initiating Cells

Ye Shen, Chun Shik Park, PhD, Koramit Suppipat, MD, Takeshi Yamada, PhD, Toni-Ann Mistretta, PhD, Daniel Lacorazza, PhD

Blood (2014) 124 (21): 3569.

https://doi.org/10.1182/blood.V124.21.3569.3569

Published: 2014

Journal Articles

KLF4 Regulates Self-Renewal of Leukemic Stem Cells in Chronic Myeloid Leukemia By Repressing Gbl Expression and Altering mTORC2 Activity

Chun Shik Park, PhD, Ye Shen, Takeshi Yamada, PhD, Koramit Suppipat, MD, Monica Puppi, MS, Daniel Lacorazza, PhD

Blood (2014) 124 (21): 1789.

https://doi.org/10.1182/blood.V124.21.1789.1789

Published: 2014

Journal Articles

Tumor Suppressor Capacity of Krüppel Like Factor 4 (KLF4) in NOTCH1-Induced T-Cell Acute Lymphoblastic Leukemia

Ye Shen, Koramit Suppipat, MD, Chun Shik Park, PhD, Takeshi Yamada, PhD, H. Daniel Lacorazza, PhD

Blood (2012) 120 (21): 1325.

https://doi.org/10.1182/blood.V120.21.1325.1325

Published: 2012

Journal Articles

Loss of Krüppel-Like Factor 4 (KLF4) Impairs the Self-Renewal of Leukemic Stem Cells

Chun Shik Park, PhD, Ye Shen, Takeshi Yamada, PhD, Koramit Suppipat, MD, H. Daniel Lacorazza, PhD

Blood (2012) 120 (21): 911.

https://doi.org/10.1182/blood.V120.21.911.911

Published: 2012

Journal Articles

Loss of Krüppel-Like Factor 4 (KLF4) Leads to Increased Self-Renewal Under Stress Conditions and Improved Survival of Hematopoietic Stem Cells

Chun Shik Park, PhD, Takeshi Yamada, PhD, Koramit Suppipat, MD, Maksim Mamonkin, H. Daniel Lacorazza, PhD

Blood (2011) 118 (21): 861.

https://doi.org/10.1182/blood.V118.21.861.861

Published: 2011

Journal Articles

Targeting AKT Signaling in Pediatric Acute Lymphoblastic Leukemia with Sulforaphane

Koramit Suppipat, MD, Evelyn Zhu, Daniel Lacorazza, PhD

Blood (2011) 118 (21): 1521.

https://doi.org/10.1182/blood.V118.21.1521.1521

Published: 2011

Journal Articles

The Transcription Factor ELF4 Promotes Survival of Myeloid Leukemic Stem Cells.

Chun Shik Park, PhD, Koramit Suppipat, MD, H. Daniel Lacorazza, PhD

Blood (2010) 116 (21): 1209.

https://doi.org/10.1182/blood.V116.21.1209.1209

Published: 2010

Journal Articles

Anti-Leukemic Property of Sulphoraphane In Precursor B Cell Acute Lymphoblastic Leukemia

Koramit Suppipat, MD, Xiao Zhu, Chun Shik Park, PhD, H. Daniel Lacorazza, PhD

Blood (2010) 116 (21): 3974.

https://doi.org/10.1182/blood.V116.21.3974.3974

Published: 2010

NARROW

A KLF4-DYRK2–mediated pathway regulating self-renewal in CML stem cells

Vitamin K3 (menadione) Induces Cytotoxicity in Chronic Myeloid Leukemia Stem Cells By Upregulating DYRK2 through the Inhibition of SIAH2 Ubiquitin Ligase

DYRK2 Inhibits the Self-Renewal of Leukemic Stem Cells in Chronic Myeloid Leukemia By Inducing Degradation of c-Myc Downstream of the Reprogramming Factor KLF4

Krüppel-like Factor 4 (KLF4) Suppresses T-Cell Acute Lymphoblastic Leukemia By Inhibiting Expression of MAP2K7 and Expansion of Leukemia Initiating Cells

KLF4 Regulates Self-Renewal of Leukemic Stem Cells in Chronic Myeloid Leukemia By Repressing Gbl Expression and Altering mTORC2 Activity

Tumor Suppressor Capacity of Krüppel Like Factor 4 (KLF4) in NOTCH1-Induced T-Cell Acute Lymphoblastic Leukemia

Loss of Krüppel-Like Factor 4 (KLF4) Impairs the Self-Renewal of Leukemic Stem Cells

Loss of Krüppel-Like Factor 4 (KLF4) Leads to Increased Self-Renewal Under Stress Conditions and Improved Survival of Hematopoietic Stem Cells

Targeting AKT Signaling in Pediatric Acute Lymphoblastic Leukemia with Sulforaphane

The Transcription Factor ELF4 Promotes Survival of Myeloid Leukemic Stem Cells.

Anti-Leukemic Property of Sulphoraphane In Precursor B Cell Acute Lymphoblastic Leukemia

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American Society of Hematology

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American Society of Hematology

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