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Journal Articles

The BET Proteins Brd4 and CBP Contribute to Severity of Anemia in EKLF/KLF1 Mutants By Driving Selective Release of Paused RNA Polymerase II

Kaustav Mukherjee, Li Xue, Haocheng Fang, Jan Frayne, James J Bieker

Blood (2024) 144 (Supplement 1): 941.

https://doi.org/10.1182/blood-2024-206035

Published: 2024

Journal Articles

Sting and Vdac Inhibitors Ameliorate Ineffective Erythropoiesis in a Mouse Model of Anemia Induced By Mutation in EKLF/KLF1

Tasleem Arif, Kaustav Mukherjee, Li Xue, James J Bieker

Blood (2024) 144 (Supplement 1): 937.

https://doi.org/10.1182/blood-2024-199202

Published: 2024

Journal Articles

A novel human cellular model of CDA IV enables comprehensive analysis revealing the molecular basis of the disease phenotype

Ivan Ferrer-Vicens, Daniel C. J. Ferguson, Marieangela C. Wilson, Kate J. Heesom, James J. Bieker, Jan Frayne

Blood (2023) 141 (25): 3039–3054.

https://doi.org/10.1182/blood.2022018735

Published: 2023

Includes: Supplemental data

Journal Articles

Mutation in Erythroid-Specific Transcription Factor EKLF/KLF1 Elevates Erythroid Metabolism and Induces Inflammation

Tasleem Arif, James J Bieker

Blood (2022) 140 (Supplement 1): 1239–1240.

https://doi.org/10.1182/blood-2022-169659

Published: 2022

Journal Articles

EKLF/Klf1 Regulates Erythroid Transcription By Its Pioneering Activity and Subsequent Control of RNA Pol II Pause-Release

Kaustav Mukherjee, James J Bieker, Venkata Srinivas Mohan Nimai Dangeti

Blood (2021) 138 (Supplement 1): 283.

https://doi.org/10.1182/blood-2021-151470

Published: 2021

Journal Articles

The Glucocorticoid Receptor-Dependent Stress Response in Human Erythropoiesis Is BCL11A-Dependent

Lilian Varricchio, Eliza Geer, Fabrizio Martelli, Maria Mazzarini, Alister Funnell, James J Bieker, Thalia Papayannopoulou, Anna Rita Migliaccio

Blood (2021) 138 (Supplement 1): 939.

https://doi.org/10.1182/blood-2021-145568

Published: 2021

Journal Articles

A master erythroid regulator gets its own GPS

Lily Jun-shen Huang, James J. Bieker

Blood (2020) 135 (25): 2209–2210.

https://doi.org/10.1182/blood.2020005882

Published: 2020

Journal Articles

A Potential Role for Genes within the mTORC1 Pathway in the Regulation of Embryonic Globin Expression Revealed By ChIP-Seq, RNA-Seq and eQTL Mapping in the Nan Anemia Mouse Model

Danitza M. Nebor, PhD, Joel H. Graber, PhD, Kevin R. Gillinder, PhD, Melissa D. Ilsley, BSc, Raymond F. Robledo, PhD, Steven L. Ciciotte, MS, Vivek Philip, PhD, James J. Bieker, PhD, Andrew C Perkins, PhD, Luanne L. Peters, PhD

Blood (2017) 130 (Supplement 1): 2203.

https://doi.org/10.1182/blood.V130.Suppl_1.2203.2203

Published: 2017

Journal Articles

Identifying Novel Modifiers of Embryonic Globin Expression By Combining Chipseq, Rnaseq and eQTL Mapping in the Adult Nan Mouse Model

Danitza Nebor, PhD, Kevin R. Gillinder, PhD, Raymond F. Robledo, PhD, Joel H. Graber, PhD, Vivek Philip, PhD, Melissa Ilsley, BSc, James J. Bieker, PhD, Andrew Perkins, PhD, Luanne L. Peters, PhD

Blood (2016) 128 (22): 398.

https://doi.org/10.1182/blood.V128.22.398.398

Published: 2016

Journal Articles

EKLF/KLF1-regulated cell cycle exit is essential for erythroblast enucleation

Merlin Nithya Gnanapragasam, Kathleen E. McGrath, Seana Catherman, Li Xue, James Palis, James J. Bieker

Blood (2016) 128 (12): 1631–1641.

https://doi.org/10.1182/blood-2016-03-706671

Published: 2016

Includes: Supplemental data

Journal Articles

Krüppeling erythropoiesis: an unexpected broad spectrum of human red blood cell disorders due to KLF1 variants

Andrew Perkins, Xiangmin Xu, Douglas R. Higgs, George P. Patrinos, Lionel Arnaud, James J. Bieker, Sjaak Philipsen, the KLF1 Consensus Workgroup

Blood (2016) 127 (15): 1856–1862.

https://doi.org/10.1182/blood-2016-01-694331

Published: 2016

Includes: Supplemental data

Journal Articles

Degenerate DNA Binding By Mutant (E339D) KLF1 Dramatically Alters the Erythroid Transcriptome in the Nan Mouse Model

Danitza Nebor, PhD, Raymond F. Robledo, PhD, Joel H. Graber, PhD, Omorose Aighewi, Lionel Blanc, PhD, Andrew C Perkins, Kevin R. Gillinder, PhD, James J. Bieker, PhD, Luanne L. Peters, PhD

Blood (2015) 126 (23): 932.

https://doi.org/10.1182/blood.V126.23.932.932

Published: 2015

Journal Articles

New Insights into the Mechanism of Dominant Anemia Caused By Zinc Finger Mutations in KLF1

Andrew C Perkins, MDPhD, Kevin R Gillinder, BSc PhD, Graham Magor, BSc, Mathieu Lajoie, BSc PhD, Timothy L Bailey, BSc PhD, Michael R Tallack, BSc PhD, Melissa Ilsley, BSc, Michael Landsberg, BSc PhD, Joel P Mackay, PhD, James J. Bieker, PhD, Luanne L. Peters, PhD

Blood (2014) 124 (21): 740.

https://doi.org/10.1182/blood.V124.21.740.740

Published: 2014

Journal Articles

KLF1: when less is more

Deepa Manwani, James J. Bieker

Blood (2014) 124 (5): 672–673.

https://doi.org/10.1182/blood-2014-05-576967

Published: 2014

Journal Articles

Identification of a New Functional HDAC Complex Composed by HDAC5, GATA1 and EKLF in Human Erythroid Cells

Lilian Varricchio, PhD, Carmela Dell'Aversana, PhD, Angela Nebbioso, MD, Giovanni Migliaccio, PhD, Lucia Altucci, MD, James J. Bieker, PhD, Anna Rita F Migliaccio, PhD

Blood (2012) 120 (21): 979.

https://doi.org/10.1182/blood.V120.21.979.979

Published: 2012

Journal Articles

Case Report of Erythroid Transcription Factor EKLF Mutation Causing a Rare Form of Congenital Dyserythropoetic Anemia in a Patient of Taiwanese Origin

W. Beau Mitchell, MD, Merlin Nithya Gnanapragasam, PhD, Julie A Jaffray, MD, James J. Bieker, PhD, Deepa Manwani, MD

Blood (2011) 118 (21): 2154.

https://doi.org/10.1182/blood.V118.21.2154.2154

Published: 2011

Journal Articles

GATA2 finds its macrophage niche

Anna Rita Migliaccio, James J. Bieker

Blood (2011) 118 (10): 2647–2649.

https://doi.org/10.1182/blood-2011-06-362772

Published: 2011

Journal Articles

The multifunctional role of EKLF/KLF1 during erythropoiesis

Miroslawa Siatecka, James J. Bieker

Blood (2011) 118 (8): 2044–2054.

https://doi.org/10.1182/blood-2011-03-331371

Published: 2011

Journal Articles

Ontogenic-Specific Increasesin HDAC1 Activity and Transcription Factor Association During the Maturation of Human Adult Erythroblasts in Vitro .

Giovanni Migliaccio, Carmela Dell’Aversana, Angela Nebbioso, Elena Alfani, Lilian arricchio, V, Antonello Mai, Pratima Chaurasia, Ronald Hoffman, James J. Bieker, Lucia Altucci, Anna Rita Migliaccio

Blood (2009) 114 (22): 1978.

https://doi.org/10.1182/blood.V114.22.1978.1978

Published: 2009

Journal Articles

Blood group antigens reveal their maker

James J. Bieker

Blood (2008) 112 (5): 1554–1555.

https://doi.org/10.1182/blood-2008-06-160580

Published: 2008

NARROW

The BET Proteins Brd4 and CBP Contribute to Severity of Anemia in EKLF/KLF1 Mutants By Driving Selective Release of Paused RNA Polymerase II

Sting and Vdac Inhibitors Ameliorate Ineffective Erythropoiesis in a Mouse Model of Anemia Induced By Mutation in EKLF/KLF1

A novel human cellular model of CDA IV enables comprehensive analysis revealing the molecular basis of the disease phenotype

Mutation in Erythroid-Specific Transcription Factor EKLF/KLF1 Elevates Erythroid Metabolism and Induces Inflammation

EKLF/Klf1 Regulates Erythroid Transcription By Its Pioneering Activity and Subsequent Control of RNA Pol II Pause-Release

The Glucocorticoid Receptor-Dependent Stress Response in Human Erythropoiesis Is BCL11A-Dependent

A master erythroid regulator gets its own GPS

A Potential Role for Genes within the mTORC1 Pathway in the Regulation of Embryonic Globin Expression Revealed By ChIP-Seq, RNA-Seq and eQTL Mapping in the Nan Anemia Mouse Model

Identifying Novel Modifiers of Embryonic Globin Expression By Combining Chipseq, Rnaseq and eQTL Mapping in the Adult Nan Mouse Model

EKLF/KLF1-regulated cell cycle exit is essential for erythroblast enucleation

Krüppeling erythropoiesis: an unexpected broad spectrum of human red blood cell disorders due to KLF1 variants

Degenerate DNA Binding By Mutant (E339D) KLF1 Dramatically Alters the Erythroid Transcriptome in the Nan Mouse Model

New Insights into the Mechanism of Dominant Anemia Caused By Zinc Finger Mutations in KLF1

KLF1: when less is more

Identification of a New Functional HDAC Complex Composed by HDAC5, GATA1 and EKLF in Human Erythroid Cells

Case Report of Erythroid Transcription Factor EKLF Mutation Causing a Rare Form of Congenital Dyserythropoetic Anemia in a Patient of Taiwanese Origin

GATA2 finds its macrophage niche

The multifunctional role of EKLF/KLF1 during erythropoiesis

Ontogenic-Specific Increasesin HDAC1 Activity and Transcription Factor Association During the Maturation of Human Adult Erythroblasts in Vitro .

Blood group antigens reveal their maker

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American Society of Hematology

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American Society of Hematology

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