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Journal Articles

Iron, FRDA, and intermediary metabolism

Kostas Pantopoulos

Blood (2021) 137 (15): 1994–1995.

https://doi.org/10.1182/blood.2021010835

Published: 2021

Journal Articles

Effects of germline DHFR and FPGS variants on methotrexate metabolism and relapse of leukemia

Blood (2020) 136 (10): 1161–1168.

https://doi.org/10.1182/blood.2020005064

Published: 2020

Includes: Supplemental data

Journal Articles

Mitochondrial carrier homolog 2 is necessary for AML survival

Blood (2020) 136 (1): 81–92.

https://doi.org/10.1182/blood.2019000106

Published: 2020

Includes: Supplemental data

Journal Articles

AMP-activated protein kinase links acetyl-CoA homeostasis to BRD4 recruitment in acute myeloid leukemia

Yajian Jiang, Tianyuan Hu, Tao Wang, Xiangguo Shi, Ayumi Kitano, Kenneth Eagle, Kevin A. Hoegenauer, Marina Y. Konopleva, Charles Y. Lin, Nicolas L. Young, Daisuke Nakada

Blood (2019) 134 (24): 2183–2194.

https://doi.org/10.1182/blood.2019001076

Published: 2019

Includes: Supplemental data

Journal Articles

NUP98-KDM5A Fusion Induces Hematopoietic Cell Proliferation and Alters Myelo-Erythropoietic Differentiation

Jonathan Miller, MD PhD, Ryan Hiltenbrand, MS, Tamara Lamprecht, BS, Aman Seth, MS, Sherif Abdelhamed, PhD, Ilaria Iacobucci, PhD, Charles G. Mullighan, MBBS, MD, Jeffery M. Klco, MD PhD

Blood (2019) 134 (Supplement_1): 3775.

https://doi.org/10.1182/blood-2019-130768

Published: 2019

Journal Articles

Epigenetic Activation of the pH Regulator MCT4 in Acute Myeloid Leukemia Exploits a Fundamental Metabolic Process of Enhancing Cell Growth through Proton Shifting

Cheuk-Him Man, David T. Scadden, MD, Francois Mercier, MD FRCPC, Nian Liu, Wentao Dong, Gregory Stephanopoulos, PhD, Li Jiang, PhD, Yookyung Jung, PhD, Charles Lin, PhD, Anskar Y.-H. Leung, MD PhD

Blood (2019) 134 (Supplement_1): 3765.

https://doi.org/10.1182/blood-2019-123604

Published: 2019

Journal Articles

Class I PI3K Is Required for HSC Differentiation

Kristina Ames, PhD, Imit Kaur, PhD, Meng Tong, Shayda Hemmati, PhD, Ellen Tein, Shira Glushakow-Smith, Lindsay Gurska, Kira Gritsman, MD PhD

Blood (2019) 134 (Supplement_1): 2461.

https://doi.org/10.1182/blood-2019-123823

Published: 2019

Journal Articles

Glycolysis Restoration Attenuates Damaged Bone Marrow Endothelial Cells

Zhong-Shi Lyu, PhD, Wei-Li Yao, Qi Wen, MD, Hong-Yan Zhao, MD, Fei-Fei Tang, Yu Wang, Lan-Ping Xu, Xiao-Hui Zhang, Hsiang-Ying Lee, PhD, Xiao-Jun Huang, Yuan Kong, MD PhD

Blood (2019) 134 (Supplement_1): 2491.

https://doi.org/10.1182/blood-2019-122794

Published: 2019

Journal Articles

Effect of Extended Platelet Storage on Platelet Metabolism and Clot Retraction

Prajeeda M Nair, PhD, Michael Adam Meledeo, PhD, Xiaowu Wu, MD MSc, Grantham Peltier, MS, Bin Liu, BS, Kristin M Reddoch-Cardenas, PhD, James Bynum, PhD, Andrew P. Cap, MD PhD

Blood (2019) 134 (Supplement_1): 2450.

https://doi.org/10.1182/blood-2019-131116

Published: 2019

Journal Articles

Characterization of Congenital Sideroblastic Anemia Model Due to ABCB7 Defects: How Do Defects in Iron-Sulfur Cluster Metabolism Lead to Ring Sideroblast Formation?

Tohru Fujiwara, MD PhD, Chie Suzuki, Tetsuro Ochi, Koya Ono, MD, Kei Saito, Noriko Fukuhara, MD PhD, Yasushi Onishi, MD PhD, Hisayuki Yokoyama, MD PhD, Shinichi Fujimaki, Yukio Nakamura, MD PhD, Hideo Harigae, MD PhD

Blood (2019) 134 (Supplement_1): 2232.

https://doi.org/10.1182/blood-2019-123918

Published: 2019

Journal Articles

The GPR68/BCL2 Axis Remodels Metabolism in AML By Relocating Calcium

Xiaofei He, B.S., Caleb Hawkins, B.S., Lauren Lawley, B.S., Mark Wunderlich, MS, Benjamin Mizukawa, Xiang-ming Zha, PhD, Stephanie Halene, MD, Jing Fang, MD PhD

Blood (2019) 134 (Supplement_1): 2661.

https://doi.org/10.1182/blood-2019-125455

Published: 2019

Journal Articles

Human Acute Leukemia Is Addicted to Branched-Chain Amino Acid Metabolism to Maintain Leukemia Stemness

Yoshikane Kikushige, MD PhD, Toshihiro Miyamoto, MD PhD, Takahiro Maeda, MD PhD, Koichi Akashi, MD PhD

Blood (2019) 134 (Supplement_1): 2516.

https://doi.org/10.1182/blood-2019-129372

Published: 2019

Journal Articles

Glutathione Metabolism Contributes to the Pathobiology of Waldenstrom's Macroglobulinemia

Shahrzad Jalali, PhD, Jie Shi, MD PhD, Hyojin Kim, PhD, Zhi-Zhang Yang, MD, Stephen M Ansell, MD

Blood (2019) 134 (Supplement_1): 3971.

https://doi.org/10.1182/blood-2019-124558

Published: 2019

Journal Articles

A Retrospective Review of Mercaptopurine Metabolism Reveals High Rate of Patients with Suboptimal Metabolites Successfully Corrected with Allopurinol

Lauren Marie Vasta, MD, Richard C Zanetti, MD, Dina S. Parekh, MD, Anne B. Warwick, MD MPH, Kenneth Lieuw, MD PhD

Blood (2019) 134 (Supplement_1): 3878.

https://doi.org/10.1182/blood-2019-126184

Published: 2019

Journal Articles

Targeting of Integrin α4/VCAM-1 with AVA4746 Modulates the Redox-Status and Metabolism in ALL and Angiogenesis

Ruan Yongsheng, MD, Enzi Jiang, MD PhD, Hye Na Kim, Heather Ogana, Mo Yang, MD, Deepa Bhojwani, MD, Alan S. Wayne, MD, Yong-Mi Kim, MD MPH, PhD

Blood (2019) 134 (Supplement_1): 3881.

https://doi.org/10.1182/blood-2019-132101

Published: 2019

Journal Articles

Impact of U2AF1 Mutations on Clinical Characteristics and RNA Splicing in Myelodysplastic Syndromes (MDS)

Bing Li, MD, Jinqin Liu, Tiejun Qin, Zefeng Xu, MD, Gang Huang, PhD, Zhijian Xiao, MD

Blood (2019) 134 (Supplement_1): 2979.

https://doi.org/10.1182/blood-2019-126346

Published: 2019

Journal Articles

Dnmt3a Mutation Confers a Selective Advantage Specifically to Cells within the Long-Term Hematopoietic Stem Cell (LT-HSC) Compartment

Elizabeth Eudy, BS, Matthew Loberg, BA, Rebecca Bell, BA, Tim Stearns, Jennifer Trowbridge, PhD

Blood (2019) 134 (Supplement_1): 448.

https://doi.org/10.1182/blood-2019-124540

Published: 2019

Journal Articles

Selective Targeting of Histone Deacetylase 11 Disables Metabolism of Myeloproliferative Neoplasms

Blood (2019) 134 (Supplement_1): 474.

https://doi.org/10.1182/blood-2019-127235

Published: 2019

Journal Articles

Alterations in Sphingomyelin Metabolism Influences Tissue Factor Procoagulant Activity and the Release of TF-Positive Microvesicles

Jue Wang, PhD, Usha Pendurthi, PhD, L. Vijaya Mohan Rao, PhD

Blood (2019) 134 (Supplement_1): 1103.

https://doi.org/10.1182/blood-2019-125933

Published: 2019

Journal Articles

Lineage Tracing in Chronic Lymphocytic Leukemia Reveals Clones with Stable Gene Expression States That Differentially Respond to Therapy

Catherine Gutierrez, Aziz Al'Khafaji, B.S., Eric Brenner, B.S., Russell Durrett, B.S., M.S., Kaitlyn Johnson, B.S., M.S., Wandi Zhang, MD, Shuqiang Li, PhD, Kenneth J. Livak, PhD, Donna S Neuberg, ScD, Amy Brock, PhD, Catherine J. Wu, MD

Blood (2019) 134 (Supplement_1): 1229.

https://doi.org/10.1182/blood-2019-129303

Published: 2019

NARROW

Iron, FRDA, and intermediary metabolism

Effects of germline DHFR and FPGS variants on methotrexate metabolism and relapse of leukemia

Mitochondrial carrier homolog 2 is necessary for AML survival

AMP-activated protein kinase links acetyl-CoA homeostasis to BRD4 recruitment in acute myeloid leukemia

NUP98-KDM5A Fusion Induces Hematopoietic Cell Proliferation and Alters Myelo-Erythropoietic Differentiation

Epigenetic Activation of the pH Regulator MCT4 in Acute Myeloid Leukemia Exploits a Fundamental Metabolic Process of Enhancing Cell Growth through Proton Shifting

Class I PI3K Is Required for HSC Differentiation

Glycolysis Restoration Attenuates Damaged Bone Marrow Endothelial Cells

Effect of Extended Platelet Storage on Platelet Metabolism and Clot Retraction

Characterization of Congenital Sideroblastic Anemia Model Due to ABCB7 Defects: How Do Defects in Iron-Sulfur Cluster Metabolism Lead to Ring Sideroblast Formation?

The GPR68/BCL2 Axis Remodels Metabolism in AML By Relocating Calcium

Human Acute Leukemia Is Addicted to Branched-Chain Amino Acid Metabolism to Maintain Leukemia Stemness

Glutathione Metabolism Contributes to the Pathobiology of Waldenstrom's Macroglobulinemia

A Retrospective Review of Mercaptopurine Metabolism Reveals High Rate of Patients with Suboptimal Metabolites Successfully Corrected with Allopurinol

Targeting of Integrin α4/VCAM-1 with AVA4746 Modulates the Redox-Status and Metabolism in ALL and Angiogenesis

Impact of U2AF1 Mutations on Clinical Characteristics and RNA Splicing in Myelodysplastic Syndromes (MDS)

Dnmt3a Mutation Confers a Selective Advantage Specifically to Cells within the Long-Term Hematopoietic Stem Cell (LT-HSC) Compartment

Selective Targeting of Histone Deacetylase 11 Disables Metabolism of Myeloproliferative Neoplasms

Alterations in Sphingomyelin Metabolism Influences Tissue Factor Procoagulant Activity and the Release of TF-Positive Microvesicles

Lineage Tracing in Chronic Lymphocytic Leukemia Reveals Clones with Stable Gene Expression States That Differentially Respond to Therapy

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American Society of Hematology

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American Society of Hematology

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