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Journal Articles

Sting Negatively Regulates Allogeneic T-Cell Responses By Constraining Antigen-Presenting Cell Function

Yongxia Wu, PhD MD, Chih-Hang Anthony Tang, Corey Mealer, David Bastian, PhD, Mohammed Hanief Sofi, PhD MS, Linlu Tian, PhD, Steven Douglas Schutt, PhD, Hee-Jin Choi, PhD, Taylor Ticer, Mengmeng Zhang, MD, Lei Huang, Andrew L. Mellor, Chih-Chi Andrew Hu, Xue-Zhong Yu, MD MS

Blood (2020) 136 (Supplement 1): 37–38.

https://doi.org/10.1182/blood-2020-139860

Published: 2020

Journal Articles

Microrna-31 Regulates T-Cell Metabolism Via HIF1α and Promotes Effector Function

Yongxia Wu, PhD MD, Mengmeng Zhang, MD, David Bastian, Mohammed Hanief Sofi, PhD MS, Steven Douglas Schutt, BS, Hee-Jin Choi, PhD, Corey Mealer, Hung D Nguyen, PhD, Linlu Tian, Xue-Zhong Yu, MD MS

Blood (2019) 134 (Supplement_1): 623.

https://doi.org/10.1182/blood-2019-131587

Published: 2019

Journal Articles

Fli-1 Regulates Multiple T-Cell Subsets during Inflammatory Responses and Experimental Graft-Versus-Host Disease

Steven Douglas Schutt, BS, David Bastian, Hee-Jin Choi, PhD, Yongxia Wu, PhD MD, Mohammed Hanief Sofi, PhD MS, Hung Nguyen, PhD, Xian Zhang, PhD, Xue-Zhong Yu, MD MS

Blood (2019) 134 (Supplement_1): 3201.

https://doi.org/10.1182/blood-2019-127577

Published: 2019

Journal Articles

Potential Role of IL-39 in the Development of Gvhd

David Bastian, Hung Nguyen, PhD, Yongxia Wu, PhD MD, Steven Douglas Schutt, BS, Mohammed Hanief Sofi, PhD MS, Yuejun Liu, PhD, Eric Bartee, PhD, Xue-Zhong Yu, MD MS

Blood (2019) 134 (Supplement_1): 3206.

https://doi.org/10.1182/blood-2019-131251

Published: 2019

Journal Articles

Targeting Sirt-1 controls GVHD by inhibiting T-cell allo-response and promoting Treg stability in mice

Anusara Daenthanasanmak, Supinya Iamsawat, Paramita Chakraborty, Hung D. Nguyen, David Bastian, Chen Liu, Shikhar Mehrotra, Xue-Zhong Yu

Blood (2019) 133 (3): 266–279.

https://doi.org/10.1182/blood-2018-07-863233

Published: 2019

Includes: Supplemental data

Journal Articles

Association of Donor T Cell Repertoire in Host Lymphoid and Target Organs and Gvhd Development

Yongxia Wu, PhD MD, Jianing Fu, PhD, Anusara Daenthanasanmak, PhD, Hung D Nguyen, PhD, Mohammed Hanief Sofi, PhD MS, Jessica Lauren Heinrichs, BS, MS, Yuejun Liu, PhD, Steven Douglas Schutt, BS, David Bastian, Xue-Zhong Yu, MD MS

Blood (2018) 132 (Supplement 1): 4525.

https://doi.org/10.1182/blood-2018-99-119956

Published: 2018

Journal Articles

MicroRNA-17-92 is required for T-cell and B-cell pathogenicity in chronic graft-versus-host disease in mice

Yongxia Wu, Steven Schutt, Katelyn Paz, Mengmeng Zhang, Ryan P. Flynn, David Bastian, M. Hanief Sofi, Hung Nguyen, Min Dai, Chen Liu, Ying-Jun Chang, Bruce R. Blazar, Xue-Zhong Yu

Blood (2018) 131 (17): 1974–1986.

https://doi.org/10.1182/blood-2017-06-789321

Published: 2018

Includes: Supplemental data

Journal Articles

NKG2D Negatively Regulates CD4 T Cells in Allo-Response in Mice

Mengmeng Zhang, MD, Yongxia Wu, PhD MD, David Bastian, Hung D Nguyen, PhD, Supinya Iamsawat, MSc, Anusara Daenthanasanmak, Fangping Chen, MD PhD, Xue-Zhong Yu, MD MS

Blood (2017) 130 (Supplement 1): 2279.

https://doi.org/10.1182/blood.V130.Suppl_1.2279.2279

Published: 2017

Journal Articles

Complement Promotes Gvhd through Suppressing Autophagy in Recipient Dendritic Cells after Allogeneic Hematopoietic Cell Transplantation in Mice

Hung D Nguyen, PhD, David Bastian, Sandeepkumar Kuril, MD, Mohammmed Dany, David Fairlie, PhD, Carl Atkinson, PhD, Besim Ogretmen, PhD, Stephen Tomlinson, PhD, Xue-Zhong Yu, MD MS

Blood (2017) 130 (Supplement 1): 1904.

https://doi.org/10.1182/blood.V130.Suppl_1.1904.1904

Published: 2017

Journal Articles

U Distinct Roles of IL-12Rβ1 and IL-23R in the Development of Acute and Chronic Gvhd

David Bastian, Hung D Nguyen, PhD, Yongxia Wu, PhD MD, Steven Douglas Schutt, BS, Anusara Daenthanasanmak, Mohammed Hanief Sofi, PhD MS, Supinya Iamsuwat, Mengmeng Zhang, MD, Xue-Zhong Yu, MD MS

Blood (2017) 130 (Supplement 1): 1005.

https://doi.org/10.1182/blood.V130.Suppl_1.1005.1005

Published: 2017

Journal Articles

Microrna-31 Promotes T-Cell Pathogenicity in Chronic Graft-Versus-Host Disease

Yongxia Wu, PhD MD, Mengmeng Zhang, MD, Mohammed Hanief Sofi, PhD MS, Steven Douglas Schutt, BS, David Bastian, Supinya Iamsawat, MSc, Xue-Zhong Yu, MD MS

Blood (2017) 130 (Supplement 1): 3165.

https://doi.org/10.1182/blood.V130.Suppl_1.3165.3165

Published: 2017

Journal Articles

Oxidative Stress Regulates T Cell Pathogenicity in Gvhd

Mohammed Hanief Sofi, PhD MS, Yongxia Wu, PhD MD, Min Dai, MD, Steven Douglas Schutt, BS, Anusara Daenthanasanmak, Jessica Lauren Heinrichs, BS, MS, Hung D Nguyen, PhD, David Bastian, Supinya Iamsawat, MSc, Mengmeng Zhang, MD, Shikhar Mehrotra, PhD, Xue-Zhong Yu, MD MS

Blood (2017) 130 (Supplement 1): 3168.

https://doi.org/10.1182/blood.V130.Suppl_1.3168.3168

Published: 2017

Journal Articles

PIM2 Kinase Regulates T-Cell Alloresponses and Graft-Versus-Host Disease in Mice

Yongxia Wu, MD PhD, Anusara Daenthanasanmak, PhD, Hung Nguyen, PhD, Jessica Lauren Heinrichs, BS, MS, David Bastian, Shikhar Mehrotra, Andrew Kraft, MD, Xue-Zhong Yu, MD MS

Blood (2015) 126 (23): 3074.

https://doi.org/10.1182/blood.V126.23.3074.3074

Published: 2015

Journal Articles

Targeting Host Complement C3a/C5a Receptors to Control of Acute Graft-Versus-Host Disease in Mice

Hung Nguyen, PhD, Jessica Lauren Heinrichs, BS, MS, Jianing Fu, PhD, Yongxia Wu, MD PhD, David Bastian, Steven Schutt, Anusara Daenthanasanmak, PhD, Mohammmed Dany, Chen Liu, MD PhD, David Fairlie, PhD, Stephen Tomlinson, PhD, Xue-Zhong Yu, MD MS

Blood (2015) 126 (23): 3076.

https://doi.org/10.1182/blood.V126.23.3076.3076

Published: 2015

Journal Articles

CD8 Tregs Promote Gvhd Prevention and Restore Impaired GVL Effect Mediated By CD4 Tregs in Mice

Jessica Lauren Heinrichs, BS, MS, Hung Nguyen, PhD, David Bastian, Yongxia Wu, MD PhD, Anusara Daenthanasanmak, PhD, Xue-Zhong Yu, MD MS

Blood (2015) 126 (23): 1873.

https://doi.org/10.1182/blood.V126.23.1873.1873

Published: 2015

Journal Articles

Targeting JAK2 By Gene Knockout or Pacritinib Treatment Reduces Gvhd and Xenograft Rejection By Promoting Induced Treg Differentiation

Brian C Betts, MD, David Bastian, Hung Nguyen, PhD, Jessica Lauren Heinrichs, BS, MS, Yongxia Wu, MD PhD, Anandharaman Veerapathran, PhD, Marie C Lee, MD, Jack Singer, MD, Claudio Anasetti, MD, Xue-Zhong Yu, MD MS

Blood (2015) 126 (23): 1874.

https://doi.org/10.1182/blood.V126.23.1874.1874

Published: 2015

Journal Articles

MicroRNA-17-92 controls T-cell responses in graft-versus-host disease and leukemia relapse in mice

Yongxia Wu, Jessica Heinrichs, David Bastian, Jianing Fu, Hung Nguyen, Steven Schutt, Yuejun Liu, Junfei Jin, Chen Liu, Qi-Jing Li, Changqing Xia, Xue-Zhong Yu

Blood (2015) 126 (11): 1314–1323.

https://doi.org/10.1182/blood-2015-02-627356

Published: 2015

Includes: Supplemental data

Journal Articles

Allogeneic T Cells Utilize Glycolysis As the Predominant Metabolic Pathway to Induce Acute Graft-Versus-Host Disease

Hung Nguyen, Kelley MK Haarberg, MS,PhD, Yongxia Wu, Jianing Fu, Jessica Lauren Heinrichs, David Bastian, Steven Schutt, B.S., Sharad Shrestha, PhD, Chen Lui, PhD, Hongbo Chi, PhD, Xue-Zhong Yu

Blood (2014) 124 (21): 2419.

https://doi.org/10.1182/blood.V124.21.2419.2419

Published: 2014

Journal Articles

Microrna-17-92 Cluster: Novel Target for Controlling Gvhd While Preserving GVL Effect

Yongxia Wu, David Bastian, Jessica Lauren Heinrichs, Jianing Fu, Hung Nguyen, Qi-Jing Li, Changqing Xia, Xue-Zhong Yu

Blood (2014) 124 (21): 845.

https://doi.org/10.1182/blood.V124.21.845.845

Published: 2014

NARROW

Sting Negatively Regulates Allogeneic T-Cell Responses By Constraining Antigen-Presenting Cell Function

Microrna-31 Regulates T-Cell Metabolism Via HIF1α and Promotes Effector Function

Fli-1 Regulates Multiple T-Cell Subsets during Inflammatory Responses and Experimental Graft-Versus-Host Disease

Potential Role of IL-39 in the Development of Gvhd

Targeting Sirt-1 controls GVHD by inhibiting T-cell allo-response and promoting Treg stability in mice

Association of Donor T Cell Repertoire in Host Lymphoid and Target Organs and Gvhd Development

MicroRNA-17-92 is required for T-cell and B-cell pathogenicity in chronic graft-versus-host disease in mice

NKG2D Negatively Regulates CD4 T Cells in Allo-Response in Mice

Complement Promotes Gvhd through Suppressing Autophagy in Recipient Dendritic Cells after Allogeneic Hematopoietic Cell Transplantation in Mice

U Distinct Roles of IL-12Rβ1 and IL-23R in the Development of Acute and Chronic Gvhd

Microrna-31 Promotes T-Cell Pathogenicity in Chronic Graft-Versus-Host Disease

Oxidative Stress Regulates T Cell Pathogenicity in Gvhd

PIM2 Kinase Regulates T-Cell Alloresponses and Graft-Versus-Host Disease in Mice

Targeting Host Complement C3a/C5a Receptors to Control of Acute Graft-Versus-Host Disease in Mice

CD8 Tregs Promote Gvhd Prevention and Restore Impaired GVL Effect Mediated By CD4 Tregs in Mice

Targeting JAK2 By Gene Knockout or Pacritinib Treatment Reduces Gvhd and Xenograft Rejection By Promoting Induced Treg Differentiation

MicroRNA-17-92 controls T-cell responses in graft-versus-host disease and leukemia relapse in mice

Allogeneic T Cells Utilize Glycolysis As the Predominant Metabolic Pathway to Induce Acute Graft-Versus-Host Disease

Microrna-17-92 Cluster: Novel Target for Controlling Gvhd While Preserving GVL Effect

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American Society of Hematology

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American Society of Hematology

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