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Journal Articles

Novel Anti-TMPRSS6 Monoclonal Antibody Provides a Potential Therapeutic Approach for the Treatment of Polycythemia Vera

Buxin Chen, Jean Wang, Lei Huang, Matthew Bujold, Xin Du
Journal: Blood
Blood (2023) 142 (Supplement 1): 3837.
https://doi.org/10.1182/blood-2023-174782
Published: 2023
Journal Articles

First-in-Human Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Factor XI Monoclonal Antibody SHR-2004 in Healthy Subjects

Tingting Ma, Bei Cao, Zuyi Weng, Yanli Dong, Shimin An, Lei Huang, Yuanxun Yang, Yan Geng, Hui Lin, Yuqi Wang, Pinhao Xie, Kai Shen, Juan Li
Journal: Blood
Blood (2023) 142 (Supplement 1): 3981.
https://doi.org/10.1182/blood-2023-173295
Published: 2023
Journal Articles

Prediction of Early Onset Cytokine Release Syndrome and Neurologic Events after Axicabtagene Ciloleucel in Large B-Cell Lymphoma Based on Machine Learning Algorithms

Qinghua Song, Tao Hu, Sattva S. Neelapu, Frederick L. Locke, Caron Jacobson, David B. Miklos, Olalekan O. Oluwole, Marie José Kersten, Max Topp, Jenny J. Kim, Kanwarjit Singh, Jorge Andrade, Lei Huang, Allen Xue, Marco Schupp, Myrna Nahas, Rhine R. Shen, Adrian Bot
Journal: Blood
Blood (2021) 138 (Supplement 1): 2833.
https://doi.org/10.1182/blood-2021-148580
Published: 2021
Journal Articles

Treating Iron Overload Disorders with a Novel Therapeutic Antibody Targeting TMPRSS6

Buxin Chen, Jean Wang, Bin Zheng, Lei Huang, Yu Mao, Zijun Ouyang, Xin Du
Journal: Blood
Blood (2021) 138 (Supplement 1): 941.
https://doi.org/10.1182/blood-2021-151418
Published: 2021
Journal Articles

Macrophage Activation By Dual PI3K-δ/γ Inhibition Enhances Anti-CD47-Mediated Phagocytosis and Prolongs Survival in DLBCL

James Godfrey, MD, Wenjun Kang, MS, Lei Huang, PhD, Silvia Coma, PhD, Roy Maute, PhD, Mark P. Chao, MD PhD, Jonathan A Pachter, PhD, Sonali Smith, MD, Justin Kline, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 40.
https://doi.org/10.1182/blood-2020-143304
Published: 2020
Journal Articles

Sting Negatively Regulates Allogeneic T-Cell Responses By Constraining Antigen-Presenting Cell Function

Yongxia Wu, PhD MD, Chih-Hang Anthony Tang, Corey Mealer, David Bastian, PhD, Mohammed Hanief Sofi, PhD MS, Linlu Tian, PhD, Steven Douglas Schutt, PhD, Hee-Jin Choi, PhD, Taylor Ticer, Mengmeng Zhang, MD, Lei Huang, Andrew L. Mellor, Chih-Chi Andrew Hu, Xue-Zhong Yu, MD MS
Journal: Blood
Blood (2020) 136 (Supplement 1): 37–38.
https://doi.org/10.1182/blood-2020-139860
Published: 2020
Journal Articles

RUNX1 Mutation Leads to Megakaryocyte-Primed Hematopoietic Stem Cell Expansion and Familial Platelet Disorder

Chen Wang, MD, Weinan Wang, BS, Lei Huang, PhD, Yoshihiro Hayashi, MD PhD, Xiongwei Cai, PhD, Xiaomei Yan, MD PhD, Gang Huang, PhD, Yi Zheng, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 8–9.
https://doi.org/10.1182/blood-2020-140769
Published: 2020
Journal Articles

In Situ Fate Mapping of Native and Stress Myelopoiesis Reveals a Unique Niche for Mono- and Dendritic Cell -Poiesis

Jizhou Zhang, Qingqing Wu, PhD, Courtney Johnson, BS, Giang Pham, PhD, Jeremy M. Kinder, Immanuel Kwok, Keith Leong, André Olsson, MS, PhD, Anastasiya Slaughter, BA, Margot Lindsay May, BS, Benjamin Weinhaus, BS, Angelo D'Alessandro, James Douglas Engel, PhD, Jean X. Jiang, PhD, J.Matthew Koffron, Lei Huang, PhD, Lai Guang Ng, Sing Sing Way, MDPhD, Nathan Salomonis, PhD, H. Leighton Grimes, PhD, Daniel Lucas-Alcaraz, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 38–39.
https://doi.org/10.1182/blood-2020-143123
Published: 2020
Journal Articles

Iron Overload Impairs Bone Marrow Mesenchymal Stromal Cells from MDS Patients and Promotes Leukemia Transformation

Rong Fu, Jr., PhD, Liu Zhaoyun, Lei Huang, Hui Liu, Zonghong Shao, MD, Kai Ding, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5398.
https://doi.org/10.1182/blood-2019-127855
Published: 2019
Journal Articles

Autism-Associated Chromatin Remodeler CHD8 Governs the Survival and Differentiation of Hematopoietic Stem/Progenitor Cells

Zhaowei Tu, PhD, Chen Wang, MSc, Chuntao Zhao, PhD, Lei Huang, PhD, Nathan Salomonis, PhD, Richard Q Lu, PhD, Yi Zheng, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1191.
https://doi.org/10.1182/blood-2019-127313
Published: 2019
Journal Articles

The Mechanisms Of Damage To Bone Marrow By Iron Overload In Patients With Immuno-Related Pancytopenia

Rong Fu, MD, Lei Huang, MD, Zonghong Shao, MD
Journal: Blood
Blood (2013) 122 (21): 5561.
https://doi.org/10.1182/blood.V122.21.5561.5561
Published: 2013
Journal Articles

Polyfunctional CD4 + T cells are essential for eradicating advanced B-cell lymphoma after chemotherapy

Zhi-Chun Ding, Lei Huang, Bruce R. Blazar, Hideo Yagita, Andrew L. Mellor, David H. Munn, Gang Zhou
Journal: Blood
Blood (2012) 120 (11): 2229–2239.
https://doi.org/10.1182/blood-2011-12-398321
Published: 2012
Includes: Supplemental data
Journal Articles

Structures of the spectrin-ankyrin interaction binding domains

Jonathan J. Ipsaro, Lei Huang, Alfonso Mondragón
Journal: Blood
Blood (2009) 113 (22): 5385–5393.
https://doi.org/10.1182/blood-2008-10-184358
Published: 2009
Includes: Multimedia, Supplemental data
Journal Articles

Immunization against murine multiple myeloma with fusions of dendritic and plasmacytoma cells is potentiated by interleukin 12

Jianlin Gong, Shigeo Koido, Dongshu Chen, Yasuhiro Tanaka, Lei Huang, David Avigan, Kenneth Anderson, Tsuneya Ohno, Donald Kufe
Journal: Blood
Blood (2002) 99 (7): 2512–2517.
https://doi.org/10.1182/blood.V99.7.2512
Published: 2002