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Journal Articles

A Single-Cell Atlas of Classical Mantle Cell Lymphoma Reveals Paired Tumor-Immune Malignant States Correlating with Prognosis

Amira Marouf, Sneha Mitra, Irem Isgor, Ashlee Joseph, Jahan Rahman, Ya-Hui Lin, Meril Takizawa, Ronan Chaligne, Shenon Sethi, Ahmet Dogan, Sandrine Roulland, Gilles Salles, Christina Leslie, Anita Kumar, Santosha A. Vardhana
Journal: Blood
Blood (2024) 144 (Supplement 1): 234.
https://doi.org/10.1182/blood-2024-206805
Published: 2024
Journal Articles

Distinct Patterns of CD4+ and CD8+ T-Cell Clonal Expansion Enable Broad Clinical Responses to Pembrolizumab + GVD in Patients with Relapsed Hodgkin Lymphoma

Beatriz Wills, Jahan Rahman, Nivetha Ganesan, Gunjan L. Shah, Ariela Noy, Heiko Schoder, Joachim Yahalom, Anita Kumar, Lorenzo Falchi, Paul A. Hamlin, Maria Lia Palomba, William Johnson, Andrew M. Intlekofer, Philip Caron, Theresa Davey, Helen Hancock, Natasha Galasso, Brittney Munayirji, Ya Hui Lin, Alayna Santarosa, Ellie Casper, Georgio Pongas, Andrew D. Zelenetz, Craig H. Moskowitz, Gilles Salles, Santosha A Vardhana, Alison Moskowitz
Journal: Blood
Blood (2023) 142 (Supplement 1): 1623.
https://doi.org/10.1182/blood-2023-185083
Published: 2023
Journal Articles

Ruxolitinib Promotes Clinical Responses in Large Granular Lymphocytic Leukemia Via Suppression of JAK/STAT-Dependent Inflammatory Cascades

Alison Moskowitz, Jahan Rahman, Nivetha Ganesan, Kelly Hannigan, Katie Ksanznak, Hadassah Bitton, Ya-Hui Lin, Theresa Davey, Helen Hancock, Leslie Perez, Tayler Miller, Jamila Brutus, Ahmet Dogan, Mark Blaine Geyer, Eric Jacobsen, Anita Kumar, Jonathan Moreira, Jae H. Park, Meghan C. Thompson, Pallawi Torka, Andrew D. Zelenetz, Santosha A Vardhana, Steven M. Horwitz
Journal: Blood
Blood (2023) 142 (Supplement 1): 183.
https://doi.org/10.1182/blood-2023-181922
Published: 2023
Journal Articles

First-in-Human Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Factor XI Monoclonal Antibody SHR-2004 in Healthy Subjects

Tingting Ma, Bei Cao, Zuyi Weng, Yanli Dong, Shimin An, Lei Huang, Yuanxun Yang, Yan Geng, Hui Lin, Yuqi Wang, Pinhao Xie, Kai Shen, Juan Li
Journal: Blood
Blood (2023) 142 (Supplement 1): 3981.
https://doi.org/10.1182/blood-2023-173295
Published: 2023
Journal Articles

Potent CD8+ T-Cell Proliferation and Effector Differentiation Following Subcutaneous (SC) Mosunetuzumab Administration in Patients with Untreated, High Tumor-Burden Follicular Lymphoma (FL)

Lorenzo Falchi, Ya-Hui Lin, Lauren Melendez, Paola Ghione, Colette Owens, Paul A. Hamlin, Jennifer Kimberly Lue, Zachary D. Epstein-Peterson, Anita Kumar, Maria Lia Palomba, Pallawi Torka, Michelle Okwali, Alexandra Ferreira Lopes, Anastasia Martinova, Lauren Wood, Clare Grieve, Walter Ramos Amador, Andrew D. Zelenetz, Gilles Salles, Santosha A Vardhana
Journal: Blood
Blood (2023) 142 (Supplement 1): 6116.
https://doi.org/10.1182/blood-2023-189638
Published: 2023
Journal Articles

ANP32B-mediated repression of p53 contributes to maintenance of normal and CML stem cells

Shuo Yang, Xiao-Na Zhu, Hui-Lin Zhang, Qian Yang, Yu-Sheng Wei, Di Zhu, Meng-Di Liu, Shao-Ming Shen, Li Xia, Ping He, Meng-Kai Ge, Yi-Lian Pan, Meng Zhao, Ying-Li Wu, Jun-Ke Zheng, Guo-Qiang Chen, Yun Yu
Journal: Blood
Blood (2021) 138 (24): 2485–2498.
https://doi.org/10.1182/blood.2020010400
Published: 2021
Includes: Supplemental data
Journal Articles

Risk Stratification for Acute Arterial and Venous Thromboembolism using CHA 2 DS 2 -VASc Score in Hospitalized COVID-19 Patients: A Multicenter Study

Yi Lee, Qasim Jehangir, Pin Li, Chun-Hui Lin, Anupam A Sule, Geetha Krishnamoorthy, Judie R Goodman, Abdul Halabi, Kiritkumar Patel, Dee Dee Wang, Laila Poisson, Girish B Nair
Journal: Blood
Blood (2021) 138 (Supplement 1): 2120.
https://doi.org/10.1182/blood-2021-146110
Published: 2021
Journal Articles

The Dysregulation of Hepcidin-Ferroportin Axis in Childhood Acute Lymphoblastic Leukemia Survivors after Completion of Chemotherapy

Hsi-Che Liu, MD, Ting-Chi Yeh, MD, Jen-Yin Hou, MD, Ting-Huan Huang, MD, Chia-Yu Sung, MD, Chun-Hui Lin, MS, Syuan-You Ye, MS, Tsai-Ying Chen, MS
Journal: Blood
Blood (2020) 136 (Supplement 1): 1.
https://doi.org/10.1182/blood-2020-141170
Published: 2020
Journal Articles

Prostaglandin E2 Promotes Recovery of Thymus in Survivors of the Hematopoietic Acute Radiation Syndrome (H-ARS)

TONG WU, MD PhD, Artur Plett, PhD, Hui Lin Chua, PhD, Louis M. Pelus, PhD, Christie M. Orschell, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1008.
https://doi.org/10.1182/blood.V130.Suppl_1.1008.1008
Published: 2017
Journal Articles

Mitigating Detrimental Influences of Ambient Air Collection of Bone Marrow By Hypoxic Collection Results in Detection of Functionally Enhanced Aged Mouse Hematopoiesis: Reflecting Stem Cell Expression Levels of CXCR4, CCR5 and ROS

Maegan Capitano, PhD, Scott Cooper, MS, Bin Guo, PhD, Jing Zhang, PhD, Xinxin Huang, PhD, Qingchun Cai, PhD, Heather A. O'Leary, PhD, Hui Lin Chua, PhD, Artur Plett, PhD, Christie M. Orschell, PhD, Hal E. Broxmeyer, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2420.
https://doi.org/10.1182/blood.V130.Suppl_1.2420.2420
Published: 2017
Journal Articles

Prostaglandin E2 Protects HSC from DNA Damage Induced By Ionizing Radiation By Preventing Generation of Reactive Oxygen Species and Histone Acetylation

Liqiong Liu, MD PhD, Andrea M Patterson, PhD, Hui Lin Chua, PhD, Carol Sampson, MS, Artur Plett, PhD, Hongge Li, PhD, Pratibha Singh, PhD, Christie M. Orschell, PhD, Louis M. Pelus, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1151.
https://doi.org/10.1182/blood.V130.Suppl_1.1151.1151
Published: 2017
Journal Articles

Prostaglandin E 2 Promotes Early Bone Marrow Reconstitution for Survival after Lethal Irradiation

Andrea M. Patterson, PhD, Pratibha Singh, PhD, Hongge Li, PhD, Hui Lin Chua, PhD, Alexa Fisher, BS, Carol Sampson, MS, Artur Plett, PhD, Christie M. Orschell, PhD, Louis M. Pelus, PhD
Journal: Blood
Blood (2016) 128 (22): 1481.
https://doi.org/10.1182/blood.V128.22.1481.1481
Published: 2016
Journal Articles

Re-Evaluation of Age-Related Dysregulation of Hematopoiesis Based on Oxygen Induced Changes Associated with Cell Collection/Processing in Ambient Air

Hal E. Broxmeyer, PhD, Maegan L. Capitano, PhD, Heather A. O'leary, PhD, Scott Cooper, MAS, Hui Lin Chua, PhD, Artur Plett, PhD, Christie M. Orschell, PhD
Journal: Blood
Blood (2016) 128 (22): 5051.
https://doi.org/10.1182/blood.V128.22.5051.5051
Published: 2016
Journal Articles

The NAE inhibitor pevonedistat interacts with the HDAC inhibitor belinostat to target AML cells by disrupting the DDR

Liang Zhou, Shuang Chen, Yu Zhang, Maciej Kmieciak, Yun Leng, Lihong Li, Hui Lin, Kathryn A. Rizzo, Catherine I. Dumur, Andrea Ferreira-Gonzalez, Mohamed Rahmani, Lawrence Povirk, Sri Chalasani, Allison J. Berger, Yun Dai, Steven Grant
Journal: Blood
Blood (2016) 127 (18): 2219–2230.
https://doi.org/10.1182/blood-2015-06-653717
Published: 2016
Includes: Supplemental data
Journal Articles

A Bim-targeting strategy overcomes adaptive bortezomib resistance in myeloma through a novel link between autophagy and apoptosis

Shuang Chen, Yu Zhang, Liang Zhou, Yun Leng, Hui Lin, Maciej Kmieciak, Xin-Yan Pei, Richard Jones, Robert Z. Orlowski, Yun Dai, Steven Grant
Journal: Blood
Blood (2014) 124 (17): 2687–2697.
https://doi.org/10.1182/blood-2014-03-564534
Published: 2014
Includes: Supplemental data
Journal Articles

Bim-Targeting Therapy Circumvents Adaptive Bortezomib-Resistance In Myeloma Through a Novel Cross-Link Between Autophagy and Apoptosis

Shuang Chen, MD/PhD, Yun Dai, MD, PhD, Yu Zhang, PhD, Liang Zhou, MD/PhD, Hui Lin, MD, Xin-Yan Pei, Robert Z. Orlowski, M.D., Ph.D., Steven Grant, MD
Journal: Blood
Blood (2013) 122 (21): 601.
https://doi.org/10.1182/blood.V122.21.601.601
Published: 2013
Journal Articles

Recovery of Hematopoiesis and Increased Survival Following Radiological Injury through Modulation of Prostaglandin E 2 (PGE 2 ) Signaling.

Jonathan Hoggatt, Ph.D., Artur Plett, Ph.D., Carol Sampson, M.S., Hui Lin Chua, Ph.D., Christie M. Orschell, Ph.D., Louis M. Pelus, PhD
Journal: Blood
Blood (2010) 116 (21): 2638.
https://doi.org/10.1182/blood.V116.21.2638.2638
Published: 2010
Journal Articles

Kinetics of Self-Renewal and Differentiation Divisions of Transplanted Hematopoietic Stem and Progenitor Cells Early After Transplantation Into Lethally-Irradiated Recipients.

Hui Lin Chua, PhD, Vikram Anand, BS, Carol Sampson, MS, Ngoc-Thinh Nguyen, BS, Artur Plett, PhD, Evan West, BS, Christie M. Orschell, PhD
Journal: Blood
Blood (2009) 114 (22): 2443.
https://doi.org/10.1182/blood.V114.22.2443.2443
Published: 2009
Journal Articles

Global reduction of the epigenetic H3K79 methylation mark and increased chromosomal instability in CALM-AF10–positive leukemias

Yi-Hui Lin, Purvi M. Kakadia, Ying Chen, Ya-Qiang Li, Aniruddha J. Deshpande, Christian Buske, Kang-Ling Zhang, Yi Zhang, Guo-Liang Xu, Stefan K. Bohlander
Journal: Blood
Blood (2009) 114 (3): 651–658.
https://doi.org/10.1182/blood-2009-03-209395
Published: 2009
Includes: Supplemental data
Journal Articles

Differential Protein Expressions Between Leukemia HL-60 and Adriamycin-Resistant HL-60 Cell Lines by Comparative Preteomic Analysis

Jian Da Hu, PhD, Min-Hui Lin, Xin-Ji Chen, Ting-Bo Liu, Lian-Huang Lv
Journal: Blood
Blood (2008) 112 (11): 5052.
https://doi.org/10.1182/blood.V112.11.5052.5052
Published: 2008