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Journal Articles

Overexpression of wild-type IL-7Rα promotes T-cell acute lymphoblastic leukemia/lymphoma

Ana Silva, Afonso R. M. Almeida, Ana Cachucho, João L. Neto, Sofie Demeyer, Mafalda de Matos, Thea Hogan, Yunlei Li, Jules Meijerink, Jan Cools, Ana Rita Grosso, Benedict Seddon, João T. Barata

Blood (2021) 138 (12): 1040–1052.

https://doi.org/10.1182/blood.2019000553

Published: 2021

Includes: Supplemental data

Journal Articles

Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma

Blood (2020) 135 (19): 1685–1695.

https://doi.org/10.1182/blood.2019003880

Published: 2020

Includes: Supplemental data

Journal Articles

IL-7R is essential for leukemia-initiating cell activity of T-cell acute lymphoblastic leukemia

Sara González-García, Marta Mosquera, Patricia Fuentes, Tiziana Palumbo, Adela Escudero, Antonio Pérez-Martínez, Manuel Ramírez, Anne E. Corcoran, Maria L. Toribio

Blood (2019) 134 (24): 2171–2182.

https://doi.org/10.1182/blood.2019000982

Published: 2019

Includes: Supplemental data

Journal Articles

Beyond Exhaustion: The PDL1-PD1 Axis Shapes the Classical Hodgkin Lymphoma Microenvironment

Joseph G Taylor, MBBS, BSc, Andrew James Clear, BSc, Edward Truelove, MBBS, BSc, MRCP, FRCPath, Mariarita Calaminici, John G. Gribben, MD DSc

Blood (2019) 134 (Supplement_1): 658.

https://doi.org/10.1182/blood-2019-125247

Published: 2019

Journal Articles

Identification and Validation of Predictive Biomarkers to CD19- and BCMA-Specific CAR T-Cell Responses in CAR T-Cell Precursors

Blood (2019) 134 (Supplement_1): 622.

https://doi.org/10.1182/blood-2019-122513

Published: 2019

Journal Articles

Potential Influence of Hematological or Immunological Hereditary Predisposition Genes on the Outcomes of Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Hematological Malignancies

Zhihui Li, Qinlong Zheng, Yongqiang Zhao, Yanzhi Song, Fan Yang, Min Jiang, Chunrong Tong, Tong Wu, MD

Blood (2019) 134 (Supplement_1): 2037.

https://doi.org/10.1182/blood-2019-126339

Published: 2019

Journal Articles

Regulatory T Cell Adoptive Immunotherapy Promotes B Cell Immunity after Haploidentical Transplantation

Sara Piccinelli, Antonella Mancusi, PhD, Eni Hoxha, Loredana Ruggeri, MD, Franca Falzetti, MD, Alessandra Carotti, MD, Adelmo Terenzi, MD, Samanta Bonato, MD, Matteo Paradiso, MD, Tiziana Zei, Roberta Iacucci Ostini, Barbara Bigerna, Brunangelo Falini, MD PhD, Mauro Di Ianni, MD PhD, Massimo Fabrizio Martelli, MD, Andrea Velardi, MD, Antonio Pierini, MD PhD

Blood (2019) 134 (Supplement_1): 1917.

https://doi.org/10.1182/blood-2019-125715

Published: 2019

Journal Articles

Enabling Gene-Edited, Regulatory-like, T Cells (edTreg) for Treatment of IPEX and Other Autoimmune Disorders

Yuchi Honaker, PhD, Karen Sommer, PhD, Noelle Dahl, Yufei Xiang, MD, PhD, Christina Lopez, PhD, Samuel Scharffenberger, Michelle Christian, Troy R. Torgerson, MD PhD, Andrew M. Scharenberg, MD, David J. Rawlings, MD

Blood (2019) 134 (Supplement_1): 2071.

https://doi.org/10.1182/blood-2019-131946

Published: 2019

Journal Articles

Immunophenotyping and Function of Peripheral Blood Mononuclear Cells in Patients Undergoing Unrelated Allogeneic Transplantation with Post-Transplantation Cyclophosphamide in Combination with ATG Anti-Graft Versus Host Disease Prophylaxis

Katia Beider, Valeria Voevoda, Noga Shem-Tov, MD, Ronit Yerushalmi, MD, Ivetta Danilesko, MD, Ania Hava Grushchenko-Polaq, Olivia Devillers, Idit Wolf, Olga Ostrovsky, PhD, Avichai Shimoni, MD, Arnon Nagler, MD MSc

Blood (2019) 134 (Supplement_1): 1989.

https://doi.org/10.1182/blood-2019-129619

Published: 2019

Journal Articles

Diffuse Large B-Cell Lymphoma Is Infiltrated with Functional CD8 + T-Cells Lacking the Hallmarks of Exhaustion

Adam Greenbaum, MD PhD, Ajay K. Gopal, MD, Jonathan R. Fromm, MD PhD, A McGarry Houghton, MD

Blood (2019) 134 (Supplement_1): 1518.

https://doi.org/10.1182/blood-2019-126217

Published: 2019

Journal Articles

The Combination of Venetoclax and Tofacitinib Induced Hematological Responses in Patients with Relapse/ Refractory T-ALL with BCL2 Expression and Surface IL7R Expression or IL7R-Pathway Mutations (On behalf of the GRAALL)

Aurélie Cabannes, MD, Aline Schmidt, MD, Eolia Brissot, MD PhD, Marie Balsat, MD, Sébastien Maury, MD PhD, Francoise Isnard, MD PhD, Patrice Chevallier, MD, Victoria Cacheux, Thomas Cluzeau, MD PhD, Carlos Graux, Ludovic Lhermitte, MD PhD, Herve Dombret, MD PhD, Nicolas Boissel, MD PhD, Vahid Asnafi, MD PhD, Philippe Rousselot, MD PhD

Blood (2019) 134 (Supplement_1): 1339.

https://doi.org/10.1182/blood-2019-130818

Published: 2019

Journal Articles

Genomic Characterization of Diffuse Large B-Cell Lymphoma Transformation from Nodular Lymphocyte Predominant Hodgkin Lymphoma

Joo Y. Song, MD, Caoimhe Egan, Alyssa Bouska, PhD, Weiwei Zhang, PhD, Qiang Gong, Girish Venkataraman, MD MBBS, Alex F. Herrera, MD, Lu Chen, PhD, Rebecca Ottesen, Joyce Niland, PhD, Victoria Bedell, Maria Valle-Catuna, Joyce Murata-Collins, PhD, Dennis D. Weisenburger, MD, Javeed Iqbal, PhD, Elaine S. Jaffe, MD, Wing C. Chan, MD

Blood (2019) 134 (Supplement_1): 1486.

https://doi.org/10.1182/blood-2019-125095

Published: 2019

Journal Articles

Novel Simultaneous Single Cell mRNA and Protein Expression Profiling Identifies Distinct Treg and T Effector Signatures in the Bone Marrow of MDS Patients

Jessica Ann Timms, Susann Winter, Steven Hargreaves, Donal P. McLornan, MB, BCh (Hons), MRCP, PhD FRCPath, Uwe Platzbecker, MD, Shahram Kordasti, MD PhD

Blood (2019) 134 (Supplement_1): 2980.

https://doi.org/10.1182/blood-2019-130355

Published: 2019

Journal Articles

Adoptive Immunotherapy with Regulatory and Conventional T Cells in Haploidentical Transplantation Primes Dendritic Cells to Promote T Cell Alloreactivity in the Bone Marrow and Tolerance in the Periphery

Mauro Di Ianni, MD PhD, Raffaella Giancola, Stefano Baldoni, Francesca Ulbar, Beatrice Del Papa, Stella Santarone, Annalisa Natale, Paola Olioso, Paolo Di Bartolomeo, Tiziana Bonfini, Patrizia Accorsi, Paolo Sportoletti, Alessandra Carotti, MD, Antonio Pierini, MD PhD, Loredana Ruggeri, MD, Franca Falzetti, MD, Massimo Fabrizio Martelli, MD, Andrea Velardi, MD

Blood (2019) 134 (Supplement_1): 3224.

https://doi.org/10.1182/blood-2019-126061

Published: 2019

Journal Articles

A Transcriptomic Continuum of Differentiation Arrest in Acute Leukemia

Jonathan Bond, Aleksandra Krzywon, Ludovic Lhermitte, MD PhD, Christophe Roumier, PharmD, Anne Roggy, Mohamed Belhocine, PhD MSc, BSc, Alexander Kheirallah, Patrick Villarese, PhD, Guillaume Hypolite, Francine Garnache-Ottou, D.Pharm PhD, Herve Dombret, MD PhD, Nicolas Boissel, MD PhD, Claude Preudhomme, PharmD, PhD, Vahid Asnafi, MD PhD, Elisa Laurenti, PhD, Elizabeth Macintyre, PhDMD

Blood (2019) 134 (Supplement_1): 2511.

https://doi.org/10.1182/blood-2019-125902

Published: 2019

Journal Articles

Ibrutinib Treatment in CLL Patients Improves T Cell Function and Blinatumomab Redirected Cytotoxicity

Meixiao Long, MD, Erich Williams, Clara Berard, Carolyn Cheney, BS, Eileen Hu, BS, Seema A. Bhat, MD, Kerry A. Rogers, MD, Jennifer Woyach, MD, Natarajan Muthusamy, DVM,PhD, John C. Byrd, MD

Blood (2019) 134 (Supplement_1): 1049.

https://doi.org/10.1182/blood-2019-125417

Published: 2019

Journal Articles

MAPK-ERK Pathway Activation: The Achilles' Heel of IL-7R‒Induced Steroid Resistance

Jordy C.G. Van Der Zwet, MD, Jessica G.C.A.M. Buijs-Gladdines, Willem K. Smits, Zhongli Chen, MSc, Jules P.P. Meijerink, PhD

Blood (2019) 134 (Supplement_1): 1292.

https://doi.org/10.1182/blood-2019-124721

Published: 2019

Journal Articles

Mesenchymal COX2-Derived PGD2 Activates an ILC2-Treg Axis to Promote Proliferation of Normal and Malignant HSPCs

Limei Wu, MD, PhD, Qiqi Lin, Zhilin Ma, Fabliha Chowdhury, Md Habibul Mazumder, Wei Du, MD PhD

Blood (2019) 134 (Supplement_1): 1208.

https://doi.org/10.1182/blood-2019-124144

Published: 2019

Journal Articles

Protein Translocation Inhibitors Overcome Cytokine-Induced Glucocorticoid Resistance in T-Cell Acute Lymphoblastic Leukemia

Lauren K. Meyer, Cristina Delgado-Martin, PhD, Phillip P. Sharp, PhD, Dustin McMinn, PhD, Christopher J. Kirk, PhD, Jack Taunton, PhD, Michelle L. Hermiston, MD PhD

Blood (2019) 134 (Supplement_1): 805.

https://doi.org/10.1182/blood-2019-127537

Published: 2019

Journal Articles

Site to Site Comparison of Follicular Lymphoma Biopsies By Single Cell RNA Sequencing

Sarah Haebe, MD, Tanaya Shree, MDPhDBA, Anuja Sathe, PhD, Grady Day, HoJoon Lee, PhD, Debra K. Czerwinski, BA, Susan Grimes, BSc, Hanlee Ji, MD, Ronald Levy, MD

Blood (2019) 134 (Supplement_1): 297.

https://doi.org/10.1182/blood-2019-129445

Published: 2019

NARROW

Overexpression of wild-type IL-7Rα promotes T-cell acute lymphoblastic leukemia/lymphoma

Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma

IL-7R is essential for leukemia-initiating cell activity of T-cell acute lymphoblastic leukemia

Beyond Exhaustion: The PDL1-PD1 Axis Shapes the Classical Hodgkin Lymphoma Microenvironment

Identification and Validation of Predictive Biomarkers to CD19- and BCMA-Specific CAR T-Cell Responses in CAR T-Cell Precursors

Potential Influence of Hematological or Immunological Hereditary Predisposition Genes on the Outcomes of Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Hematological Malignancies

Regulatory T Cell Adoptive Immunotherapy Promotes B Cell Immunity after Haploidentical Transplantation

Enabling Gene-Edited, Regulatory-like, T Cells (edTreg) for Treatment of IPEX and Other Autoimmune Disorders

Immunophenotyping and Function of Peripheral Blood Mononuclear Cells in Patients Undergoing Unrelated Allogeneic Transplantation with Post-Transplantation Cyclophosphamide in Combination with ATG Anti-Graft Versus Host Disease Prophylaxis

Diffuse Large B-Cell Lymphoma Is Infiltrated with Functional CD8 + T-Cells Lacking the Hallmarks of Exhaustion

The Combination of Venetoclax and Tofacitinib Induced Hematological Responses in Patients with Relapse/ Refractory T-ALL with BCL2 Expression and Surface IL7R Expression or IL7R-Pathway Mutations (On behalf of the GRAALL)

Genomic Characterization of Diffuse Large B-Cell Lymphoma Transformation from Nodular Lymphocyte Predominant Hodgkin Lymphoma

Novel Simultaneous Single Cell mRNA and Protein Expression Profiling Identifies Distinct Treg and T Effector Signatures in the Bone Marrow of MDS Patients

Adoptive Immunotherapy with Regulatory and Conventional T Cells in Haploidentical Transplantation Primes Dendritic Cells to Promote T Cell Alloreactivity in the Bone Marrow and Tolerance in the Periphery

A Transcriptomic Continuum of Differentiation Arrest in Acute Leukemia

Ibrutinib Treatment in CLL Patients Improves T Cell Function and Blinatumomab Redirected Cytotoxicity

MAPK-ERK Pathway Activation: The Achilles' Heel of IL-7R‒Induced Steroid Resistance

Mesenchymal COX2-Derived PGD2 Activates an ILC2-Treg Axis to Promote Proliferation of Normal and Malignant HSPCs

Protein Translocation Inhibitors Overcome Cytokine-Induced Glucocorticoid Resistance in T-Cell Acute Lymphoblastic Leukemia

Site to Site Comparison of Follicular Lymphoma Biopsies By Single Cell RNA Sequencing

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American Society of Hematology

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American Society of Hematology

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