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Journal Articles

Glucocorticoids enhance the antileukemic activity of FLT3 inhibitors in FLT3-mutant acute myeloid leukemia

Melat T. Gebru, Jennifer M. Atkinson, Megan M. Young, Lijun Zhang, Zhenyuan Tang, Zhenqiu Liu, Pinyi Lu, Christopher M. Dower, Longgui Chen, Charyguly Annageldiyev, Arati Sharma, Yuka Imamura Kawasawa, Zhongming Zhao, Barbara A. Miller, David F. Claxton, Hong-Gang Wang

Blood (2020) 136 (9): 1067–1079.

https://doi.org/10.1182/blood.2019003124

Published: 2020

Includes: Supplemental data

Journal Articles

B Cell Restricted Expression of Mutated IKZF3 modulates BCR Signaling and Homing Pathways in a Mouse Model of CLL

Gregory Lazarian, PharmD, Shanye Yin, PhD, Elisa Ten Hacken, PhD, Tomasz Sewastianik, MSc,PhD, Alba Font-tello, PhD, Heather Joyal, Elizabeth Witten, Mei Zheng, Christopher J. Ott, PhD, Donna S Neuberg, ScD, Lili Wang, MD PhD, Ruben D. Carrasco, MD PhD, Catherine J. Wu, MD

Blood (2019) 134 (Supplement_1): 848.

https://doi.org/10.1182/blood-2019-123963

Published: 2019

Journal Articles

Glucocorticoid Resistance in IKZF1-Deleted BCP-ALL: It Is PTEN Again

Laurens Van Der Meer, PhD, Rene Marke, MSc, Miriam Butler, MSc, Dorette van Ingen Schenau, MSc, Blanca Scheijen, PhD, Frank van Leeuwen, PhD

Blood (2018) 132 (Supplement 1): 4088.

https://doi.org/10.1182/blood-2018-99-112888

Published: 2018

Journal Articles

Suppression of B-cell development genes is key to glucocorticoid efficacy in treatment of acute lymphoblastic leukemia

Karina A. Kruth, Mimi Fang, Dawne N. Shelton, Ossama Abu-Halawa, Ryan Mahling, Hongxing Yang, Jonathan S. Weissman, Mignon L. Loh, Markus Müschen, Sarah K. Tasian, Michael C. Bassik, Martin Kampmann, Miles A. Pufall

Blood (2017) 129 (22): 3000–3008.

https://doi.org/10.1182/blood-2017-02-766204

Published: 2017

Includes: Supplemental data

Journal Articles

Targeting BCL6 and Germinal Centers (GCs) in Chronic Graft-Versus-Host Disease (cGVHD) Using Direct and Epigenomic Therapies

Blood (2014) 124 (21): 535.

https://doi.org/10.1182/blood.V124.21.535.535

Published: 2014

Journal Articles

GCS-100 Induces Apoptosis of Acute Myeloid Leukemia Cells By Disrupting Galectin-Mediated Survival Signaling

Richard E. Davis, MD, Vivian R Ruvolo, MA, Zhiqiang Wang, Wencai Ma, PhD, Wendy D. Schober, MLT (ASCP), James Rolke, George Tidmarsh, MD PhD, Michael Andreeff, MD PhD, Peter P. Ruvolo, PhD

Blood (2014) 124 (21): 904.

https://doi.org/10.1182/blood.V124.21.904.904

Published: 2014

Journal Articles

The Bcl6 RD2 Domain Is Essential For Pre-Germinal Center B Cell Development

Chuanxin Huang, PhD, Ann Haberman, PhD, Ari M. Melnick, MD

Blood (2013) 122 (21): 783.

https://doi.org/10.1182/blood.V122.21.783.783

Published: 2013

Journal Articles

Cell-intrinsic regulation of murine dendritic cell function and survival by prereceptor amplification of glucocorticoid

Annelise Soulier, Sandra M. Blois, Shivajanani Sivakumaran, Farnaz Fallah-Arani, Stephen Henderson, Barry Flutter, Elizabeth H. Rabbitt, Paul M. Stewart, Gareth G. Lavery, Clare Bennett, S. John Curnow, Ronjon Chakraverty

Blood (2013) 122 (19): 3288–3297.

https://doi.org/10.1182/blood-2013-03-489138

Published: 2013

Includes: Supplemental data

Journal Articles

IL-12 receptor β1 deficiency alters in vivo T follicular helper cell response in humans

Nathalie Schmitt, Jacinta Bustamante, Laure Bourdery, Salah Eddine Bentebibel, Stephanie Boisson-Dupuis, Fran Hamlin, Mau V. Tran, Derek Blankenship, Virginia Pascual, Daniel A. Savino, Jacques Banchereau, Jean-Laurent Casanova, Hideki Ueno

Blood (2013) 121 (17): 3375–3385.

https://doi.org/10.1182/blood-2012-08-448902

Published: 2013

Includes: Supplemental data

Journal Articles

Splenic proliferative lymphoid nodules distinct from germinal centers are sites of autoantigen stimulation in immune thrombocytopenia

Capucine Daridon, Christoph Loddenkemper, Simone Spieckermann, Anja A. Kühl, Abdulgabar Salama, Gerd R. Burmester, Peter E. Lipsky, Thomas Dörner

Blood (2012) 120 (25): 5021–5031.

https://doi.org/10.1182/blood-2012-04-424648

Published: 2012

Includes: Supplemental data

Journal Articles

Galectin-3 binds to CD45 on diffuse large B-cell lymphoma cells to regulate susceptibility to cell death

Mary C. Clark, Mabel Pang, Daniel K. Hsu, Fu-Tong Liu, Sven de Vos, Randy D. Gascoyne, Jonathan Said, Linda G. Baum

Blood (2012) 120 (23): 4635–4644.

https://doi.org/10.1182/blood-2012-06-438234

Published: 2012

Includes: Supplemental data

Journal Articles

An Alternative Method for Myeloablative Allogenic Stem Cell Transplantation in Hematological Malignancies: Reduced BUCY2 and GCS-F Primed Bone Marrow Stem Cells

Eucario León-Rodríguez, MD, Patricia Guzmán-Uribe, MD, Sandra Ileana Pérez-Álvarez, MD, Andrea Castro-Sánchez, MD, Karla Adriana Espinosa-Bautista, MD, Alejandra Armengol-Alonso, MD, Elena Tuna-Aguilar, MD, Yvette Neme-Yunes, MD, Irma Espinosa-Poblano, MD, Antonio Velázquez-González, MD

Blood (2012) 120 (21): 4138.

https://doi.org/10.1182/blood.V120.21.4138.4138

Published: 2012

Journal Articles

NEK2 Regulates Immature B Cell Development and GC Formation in NEK2 Transgenic Mouse

Wen Zhou, PhD, Xiao He, He Wang, Mohamed E Salama, M.D., Xia Jiliang, Hongwei Xu, MD, MS, Maurizio Zangari, MD, Guido J. Tricot, MD, PhD, Fenghuang Zhan, MD, PhD

Blood (2012) 120 (21): 257.

https://doi.org/10.1182/blood.V120.21.257.257

Published: 2012

Journal Articles

Identification of human germinal center light and dark zone cells and their relationship to human B-cell lymphomas

Gabriel D. Victora, David Dominguez-Sola, Antony B. Holmes, Stephanie Deroubaix, Riccardo Dalla-Favera, Michel C. Nussenzweig

Blood (2012) 120 (11): 2240–2248.

https://doi.org/10.1182/blood-2012-03-415380

Published: 2012

Includes: Supplemental data

Journal Articles

LITAF , a BCL6 Target Gene, Regulates Autophagia in B Cells and Is Essential for T-Cell Dependent Humoral Responses

Cristina Bertolo, PhD, Raquel Malumbres, PhD, Ainara Sagardoy, PhD, Eloy F Robles, PhD, Jose I Martinez-Ferrandis, PhD, Sergio Roa, PhD, Izidore S Lossos, MD, Xavier Sagaert, MD PhD, Ari Melnick, MD, Salomon Amar, MD, Jose A Martinez-Climent, MD, PhD

Blood (2011) 118 (21): 1391.

https://doi.org/10.1182/blood.V118.21.1391.1391

Published: 2011

Journal Articles

FOXO3a Mediates Both the Pro-Survival and Proapoptotic Effects of Glucocorticoids In Acute Lymphoblastic Leuekmia

Sandeep Gurbuxani, MBBS, PhD, Margo P Emont, Barbara L. Kee, PhD, Marcus E Peter, PhD

Blood (2010) 116 (21): 1822.

https://doi.org/10.1182/blood.V116.21.1822.1822

Published: 2010

Journal Articles

Glucocorticoids promote survival of anti-inflammatory macrophages via stimulation of adenosine receptor A3

Katarzyna Barczyk, Jan Ehrchen, Klaus Tenbrock, Martina Ahlmann, Jessica Kneidl, Dorothee Viemann, Johannes Roth

Blood (2010) 116 (3): 446–455.

https://doi.org/10.1182/blood-2009-10-247106

Published: 2010

Journal Articles

BTG1 regulates glucocorticoid receptor autoinduction in acute lymphoblastic leukemia

Joost C. van Galen, Roland P. Kuiper, Liesbeth van Emst, Marloes Levers, Esther Tijchon, Blanca Scheijen, Esmé Waanders, Simon V. van Reijmersdal, Christian Gilissen, Ad Geurts van Kessel, Peter M. Hoogerbrugge, Frank N. van Leeuwen

Blood (2010) 115 (23): 4810–4819.

https://doi.org/10.1182/blood-2009-05-223081

Published: 2010

Includes: Supplemental data

Journal Articles

GCS-100, a novel galectin-3 antagonist, modulates MCL-1, NOXA, and cell cycle to induce myeloma cell death

Matthew J. Streetly, Lenushka Maharaj, Simon Joel, Steve A. Schey, John G. Gribben, Finbarr E. Cotter

Blood (2010) 115 (19): 3939–3948.

https://doi.org/10.1182/blood-2009-10-251660

Published: 2010

Journal Articles

BCL6 Is Critical for the Development of a Diverse Primary B Cell Repertoire.

Cihangir Duy, J. Jessica Yu, Srividya Swaminathan, Rahul R. Nahar, Soo-mi Kweon, Jose M. Polo, PhD, Ester Valls, Lars Klemm, Leandro Cerchietti, Gregor von Levetzow, Sebastian Herzog, Hassan Jumaa, Ignacio Moreno de Alborán, Ari Melnick, B. Hilda Ye, PhD, Markus Müschen

Blood (2009) 114 (22): 91.

https://doi.org/10.1182/blood.V114.22.91.91

Published: 2009

NARROW

Glucocorticoids enhance the antileukemic activity of FLT3 inhibitors in FLT3-mutant acute myeloid leukemia

B Cell Restricted Expression of Mutated IKZF3 modulates BCR Signaling and Homing Pathways in a Mouse Model of CLL

Glucocorticoid Resistance in IKZF1-Deleted BCP-ALL: It Is PTEN Again

Suppression of B-cell development genes is key to glucocorticoid efficacy in treatment of acute lymphoblastic leukemia

Targeting BCL6 and Germinal Centers (GCs) in Chronic Graft-Versus-Host Disease (cGVHD) Using Direct and Epigenomic Therapies

GCS-100 Induces Apoptosis of Acute Myeloid Leukemia Cells By Disrupting Galectin-Mediated Survival Signaling

The Bcl6 RD2 Domain Is Essential For Pre-Germinal Center B Cell Development

Cell-intrinsic regulation of murine dendritic cell function and survival by prereceptor amplification of glucocorticoid

IL-12 receptor β1 deficiency alters in vivo T follicular helper cell response in humans

Splenic proliferative lymphoid nodules distinct from germinal centers are sites of autoantigen stimulation in immune thrombocytopenia

Galectin-3 binds to CD45 on diffuse large B-cell lymphoma cells to regulate susceptibility to cell death

An Alternative Method for Myeloablative Allogenic Stem Cell Transplantation in Hematological Malignancies: Reduced BUCY2 and GCS-F Primed Bone Marrow Stem Cells

NEK2 Regulates Immature B Cell Development and GC Formation in NEK2 Transgenic Mouse

Identification of human germinal center light and dark zone cells and their relationship to human B-cell lymphomas

LITAF , a BCL6 Target Gene, Regulates Autophagia in B Cells and Is Essential for T-Cell Dependent Humoral Responses

FOXO3a Mediates Both the Pro-Survival and Proapoptotic Effects of Glucocorticoids In Acute Lymphoblastic Leuekmia

Glucocorticoids promote survival of anti-inflammatory macrophages via stimulation of adenosine receptor A3

BTG1 regulates glucocorticoid receptor autoinduction in acute lymphoblastic leukemia

GCS-100, a novel galectin-3 antagonist, modulates MCL-1, NOXA, and cell cycle to induce myeloma cell death

BCL6 Is Critical for the Development of a Diverse Primary B Cell Repertoire.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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