1-11 of 11
Simon Joel
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

SKIP Is Underexpressed in AML Leading to Sphingosine Kinase Hypofunction

Essam Ghazaly, MD PhD, Paul Smith, PhD, Chathunissa Gnanaranjan, MSc, Bryan D Young, BSc, PhD, Simon Joel, PhD, John G. Gribben, MD DSc, David C Taussig, PhD MRCP, FRCPath
Journal: Blood
Blood (2014) 124 (21): 5324.
https://doi.org/10.1182/blood.V124.21.5324.5324
Published: 2014
Journal Articles

P110α-mediated constitutive PI3K signaling limits the efficacy of p110δ-selective inhibition in mantle cell lymphoma, particularly with multiple relapse

Sunil Iyengar, Andrew Clear, Csaba Bödör, Lenushka Maharaj, Abigail Lee, Maria Calaminici, Janet Matthews, Sameena Iqbal, Rebecca Auer, John Gribben, Simon Joel
Journal: Blood
Blood (2013) 121 (12): 2274–2284.
https://doi.org/10.1182/blood-2012-10-460832
Published: 2013
Journal Articles

IL-6, IL-8 and VEGF Neutralisation Restores Drug Sensitivity to Conventional and Novel Treatment Combinations in a Multiple Myeloma Bone Marrow Micro-Environment Model.

Lenushka Maharaj, Rakesh Popat, John G Gribben, Simon Joel
Journal: Blood
Blood (2012) 120 (21): 2949.
https://doi.org/10.1182/blood.V120.21.2949.2949
Published: 2012
Journal Articles

Human Primary Mantle Cell Lymphoma Can Be Established in NOD/SCID/IL2Rγ-Null Mice

Sunil Iyengar, MD, Linda Ariza-McNaughton, MSc, Andrew James Clear, BSc, Amy Roe, Debra Lillington, PhD, David C Taussig, PhD, MRCP, FRCPath, John G Gribben, Simon Joel, Dominique Bonnet, PhD
Journal: Blood
Blood (2012) 120 (21): 1565.
https://doi.org/10.1182/blood.V120.21.1565.1565
Published: 2012
Journal Articles

Increased Tonic PI3K Signaling Through p110α Can Limit the Efficacy of P110δ-Selective Inhibition in Mantle Cell Lymphoma, Particularly with Multiple Relapse

Sunil Iyengar, MD, Andrew James Clear, BSc, Csaba Bödör, PhD, Lenushka Maharaj, Janet Matthews, Rebecca Auer, MD, Sameena Iqbal, John G Gribben, Simon Joel
Journal: Blood
Blood (2012) 120 (21): 1652.
https://doi.org/10.1182/blood.V120.21.1652.1652
Published: 2012
Journal Articles

PI3K Inhibition with GDC-0941 Has Greater Efficacy Compared to p110δ-Selective Inhibition with CAL-101 in Mantle Cell Lymphoma and May Be Particularly Advantageous in Multiply Relapsed Patients

Sunil Iyengar, MD, Andrew J. Clear, BSc, Andrew Owen, Lenushka Maharaj, MSc, Janet Matthews, Maria Calaminici, MD, Rebecca Auer, MD, Essam Ghazaly, MD, Sameena Iqbal, John G. Gribben, MD, DSc, Simon Joel, BSc(Hons), PhD
Journal: Blood
Blood (2011) 118 (21): 1654.
https://doi.org/10.1182/blood.V118.21.1654.1654
Published: 2011
Journal Articles

GCS-100, a novel galectin-3 antagonist, modulates MCL-1, NOXA, and cell cycle to induce myeloma cell death

Matthew J. Streetly, Lenushka Maharaj, Simon Joel, Steve A. Schey, John G. Gribben, Finbarr E. Cotter
Journal: Blood
Blood (2010) 115 (19): 3939–3948.
https://doi.org/10.1182/blood-2009-10-251660
Published: 2010
Journal Articles

A European Phase II Study (BIOV-111) of Clofarabine (Evoltra®) in Refractory and Relapsed Childhood Acute Lymphoblastic Leukemia: Final Results.

Pamela Kearns, MD, PhD, Gerard Michel, MD, Brigitte Nelken, MD, Simon Joel, PhD, Essam Al-Ghazaly, PhD, Auke Beishuizen, MD, PhD, Valentino Conter, MD, Gunter Henze, MD, Andre Baruchel, MD, Vaskar Saha, MD, PhD
Journal: Blood
Blood (2007) 110 (11): 11.
https://doi.org/10.1182/blood.V110.11.11.11
Published: 2007
Journal Articles

BIOV-111 a European Phase II Trial of Clofarabine (Evoltra ® ) in Refractory and Relapsed Childhood Acute Lymphoblastic Leukemia.

Pamela Kearns, MD,PhD, Gerard Michel, MD, Brigitte Nelken, MD, Simon Joel, PhD, Essam Al-Ghazaly, MD, Auke Beishuizen, MD,PhD, Valentino Conter, MD, Helmut Gadner, MD, Gunter Henze, MD, Hazel Smith, PhD, Andre Baruchel, MD, Vaskar Saha, MD, PhD
Journal: Blood
Blood (2006) 108 (11): 1859.
https://doi.org/10.1182/blood.V108.11.1859.1859
Published: 2006
Journal Articles

Cannabis-induced cytotoxicity in leukemic cell lines: the role of the cannabinoid receptors and the MAPK pathway

Thomas Powles, Robert te Poele, Jonathan Shamash, Tracy Chaplin, David Propper, Simon Joel, Tim Oliver, Wai Man Liu
Journal: Blood
Blood (2005) 105 (3): 1214–1221.
https://doi.org/10.1182/blood-2004-03-1182
Published: 2005
Journal Articles

The Induction of Apoptosis in Lymphoma Cells by Methylseleninic Acid and Selenodiglutathione.

Kim Last, Jackie Perry, Lenushska Maharaj, Sandra Strauss, Andrew Davies, Spyros Skoulakis, Jude Fitzgibbon, Andrew Lister, Simon Joel
Journal: Blood
Blood (2004) 104 (11): 2502.
https://doi.org/10.1182/blood.V104.11.2502.2502
Published: 2004