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Journal Articles

Structural characterization of a novel GPVI-nanobody complex reveals a biologically active domain-swapped GPVI dimer

Free
Alexandre Slater, Ying Di, Joanne C. Clark, Natalie J. Jooss, Eleyna M. Martin, Fawaz Alenazy, Mark R. Thomas, Robert A. S. Ariëns, Andrew B. Herr, Natalie S. Poulter, Jonas Emsley, Steve P. Watson
Journal: Blood
Blood (2021) 137 (24): 3443–3453.
https://doi.org/10.1182/blood.2020009440
Published: 2021
Includes: Multimedia, Supplemental data
Journal Articles

Taking aim at IDH in fitter patients with AML

Free
Andrew H. Wei, Naval Daver
Journal: Blood
Blood (2021) 137 (13): 1706–1707.
https://doi.org/10.1182/blood.2020009361
Published: 2021
Journal Articles

Ivosidenib or enasidenib combined with intensive chemotherapy in patients with newly diagnosed AML: a phase 1 study

Free
Clinical Trials & Observations
Eytan M. Stein, Courtney D. DiNardo, Amir T. Fathi, Alice S. Mims, Keith W. Pratz, Michael R. Savona, Anthony S. Stein, Richard M. Stone, Eric S. Winer, Christopher S. Seet, Hartmut Döhner, Daniel A. Pollyea, James K. McCloskey, Olatoyosi Odenike, Bob Löwenberg, Gert J. Ossenkoppele, Prapti A. Patel, Mikhail Roshal, Mark G. Frattini, Frederik Lersch, Aleksandra Franovic, Salah Nabhan, Bin Fan, Sung Choe, Hongfang Wang, Bin Wu, Lei Hua, Caroline Almon, Michael Cooper, Hagop M. Kantarjian, Martin S. Tallman
Journal: Blood
Blood (2021) 137 (13): 1792–1803.
https://doi.org/10.1182/blood.2020007233
Published: 2021
Includes: Supplemental data
Journal Articles

Venetoclax and DLI for Patients with Early Relapse of Acute Myeloid Leukemia after Allogeneic Hematopoietic Stem Cell Transplantation. a Historical Prospective Multicenter Trial

Free
Odelia Amit, MD, Yael Bar-On, MD, Galit Perets, MD, Lena Atlas, Liat Shargian, MD, Moshe Yeshurun, MD, Bruria Yachini, RN, Chen Karni, RN, Ron Ram, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2018.
https://doi.org/10.1182/blood-2019-126999
Published: 2019
Journal Articles

Protein Cysteine Sulfenylation By CD36-Dependent Reactive Oxygen Species Signaling Promotes Platelet Activation

Free
Moua Yang, PhD, Calvin Harberg, Wenjing Chen, Sarah L. Wynia-Smith, PhD, Kate S. Carroll, PhD, Jacek Zielonka, PhD, Roy L. Silverstein, MD, Brian C. Smith, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2338.
https://doi.org/10.1182/blood-2019-122465
Published: 2019
Journal Articles

Biomarkers of Hemostatic Activation and Inflammation Are Associated with Altered Coagulation Parameters in Sepsis Patients

Free
Emily Bontekoe, Matthew T. Rondina, MD, Debra Hoppensteadt, PhD, Elizabeth Middleton, MD, Antoinette Blair, Fakiha Siddiqui, Divya Joshi, Alyssandra Abrenica, Iman Darwish, Maryanne Amour, Jawed Fareed, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2401.
https://doi.org/10.1182/blood-2019-130420
Published: 2019
Journal Articles

Soluble P-Selectin Levels in Patients with Sickle Cell Disease Reflect Platelets' Activation Rather Than Endothelial Dysfunction

Free
Ersi Voskaridou, Mantzou Aimilia, PhD, Pagona Flevari, MD, Maria Dimopoulou, MD, Veroniki Komninaka, MD, Konstantina Repa, MD, Ioannis Papassotiriou, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4829.
https://doi.org/10.1182/blood-2019-122524
Published: 2019
Journal Articles

Updated Results of a Phase II Study of Reduced-Intensity Chemotherapy with Mini-Hyper-CVD in Combination with Inotuzumab Ozogamicin, with or without Blinatumomab, in Older Adults with Newly Diagnosed Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia

Free
Nicholas J. Short, MD, Hagop M. Kantarjian, MD, Farhad Ravandi, MD, Xuelin Huang, PhD, Nitin Jain, MD, Koji Sasaki, MD, Rita Khouri, Naval G. Daver, MD, Naveen Pemmaraju, MD, Joseph D. Khoury, MD, Jeffrey L. Jorgensen, MD PhD, Yesid Alvarado, MD, Marina Y Konopleva, MD PhD, Guillermo Garcia-Manero, MD, Tapan M. Kadia, MD, Musa E. Yilmaz, MD, Gautam M. Borthakur, MD, Jan A. Burger, MD PhD, Steven M. Kornblau, MD, William G. Wierda, MD PhD, Courtney D. DiNardo, MD MSc, Alessandra Ferrajoli, MD, Jovitta Jacob, RN, Meagan Rostykus, RN, Rebecca Garris, MSc, Marygrace Ward, RDC, Binru Huang, RDC, Corabelle Encarnacion, RDC, Christopher Loiselle, BS, Susan M. O'Brien, MD, Elias Jabbour, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 823.
https://doi.org/10.1182/blood-2019-125136
Published: 2019
Journal Articles

Clinical Spectrum, Long-Term Outcomes and Predictors of Relapse after Imatinib Discontinuation in FIP1L1-Pdgfra-Associated Chronic Eosinophilic Leukemia: Data from 150 Patients

Free
Julien Rohmer, MD, Matthieu Groh, MD, Julie Trichereau, Kewin Panel, Claude Preudhomme, PharmD, PhD, Fanny Legrand, PhD PharmD, Felix Ackermann, MD, Amélie Couteau-Chardon, MD, Mikael Ebbo, MD PhD, Olivier Fain, MD, Lionel Galicier, MD, Mohamed Hamidou, Mathilde Hunault, MD PhD, Etienne Lengline, MD, Catherine Mohr, MD, Franck E Nicolini, MD PhD, Jerome Rey, Louis Terriou, MD, Chafika Morati Hafsaoui, MD, Suzanne Tavitian, MD, Irene Machelart, Katayoun Jondeau, MD, Bertrand Arnulf, Jean-Christophe Ianotto, MD PhD, Jean-Marc Zini, Viviane Dubruille, MD, Francoise Huguet, MD, Borhane Slama, MD, Fabrice Jardin, Didier Adiko, Elise Toussaint, MD, Aurelien Guffroy, MD PhD, Faustine Lhomme, MD PhD, Nathalie Grardel, Cyrielle Gesquieres, Guillaume Lefèvre, MD PhD, Jean Emmanuel Kahn, PhDMD
Journal: Blood
Blood (2019) 134 (Supplement_1): 840.
https://doi.org/10.1182/blood-2019-130009
Published: 2019
Journal Articles

Durable Remission and Long-Term Survival in Relapsed/Refractory (r/r) AML Patients Treated with Guadecitabine, Median Survival Not Reached for Responders after Long Term Follow up from Phase 2 Study of 103 Patients

Free
Elizabeth A. Griffiths, MD, Hagop M. Kantarjian, MD, Casey L. O'Connell, MD, Karen W.L. Yee, MD, Wendy Stock, MD, Naval G. Daver, MD, Elias Jabbour, MD, Ellen K. Ritchie, MD, Jean-Pierre Issa, MD, Katherine J. Walsh, MD, David A. Rizzieri, MD, Scott D. Lunin, MD, Xiang Yao Su, PhD, Mohammad Azab, MD, Gail J. Roboz, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1319.
https://doi.org/10.1182/blood-2019-131394
Published: 2019
Journal Articles

Combination of Anti-CD19 and Anti-CD20 Chimeric Antigen Receptor T Cells for Relapsed and Refractory Diffuse Larger B Cell Lymphoma: An Open-Label, Single-Arm, Phase Ⅰ/Ⅱ Trial

Free
Wei Sang, MD, Ming Shi, Jingjing Yang, Jiang Cao, MD, Linyan Xu, PhD, Dongmei Yan, Xuguang Song, Cai Sun, Depeng Li, Feng Zhu, Zhenyu Li, MD, Junnian Zheng, Jianlin Qiao, PhD, Kailin Xu, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1590.
https://doi.org/10.1182/blood-2019-127640
Published: 2019
Journal Articles

HM43239, a Novel Potent Small Molecule FLT3 Inhibitor, in Acute Myeloid Leukemia (AML) with FMS-like Tyrosine Kinase 3 (FLT3) Mutations: Phase 1 /2 Study

Free
Naval G. Daver, MD, Kyoo Hyung Lee, MD PhD, Sung-Soo Yoon, MD PhD, Chul Won Jung, MD PhD, Hyun Jeong Kang, Sooa Jung, Sujin Seo, Jiyeon Yoon, Hyunjin Kim, Young Su Noh, Yoonha Seo, Hyeyoung Kwon, Oakpil Han, Seungjae Baek, MD PhD, Kyounghee Seo, Kwee Hyun Suh, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1331.
https://doi.org/10.1182/blood-2019-129670
Published: 2019
Journal Articles

Sequential CD19- and Bcma-Specific Chimeric Antigen Receptor T Cell Treatment for RRMM: Report from a Single Center Study

Free
Lingzhi Yan, Zhi Yan, Jingjing Shang, Xiaolan Shi, Song Jin, Liqing Kang, Su Qu, Jin Zhou, Huizhu Kang, Ruju Wang, Ying Yao, Jing Wang, Weiqin Yao, Guanghua Chen, Lei Yu, Depei Wu, MD PhD, Fu Cheng Cheng, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 578.
https://doi.org/10.1182/blood-2019-129740
Published: 2019
Journal Articles

Enasidenib Plus Azacitidine Significantly Improves Complete Remission and Overall Response Compared with Azacitidine Alone in Patients with Newly Diagnosed Acute Myeloid Leukemia (AML) with Isocitrate Dehydrogenase 2 ( IDH2 ) Mutations: Interim Phase II Results from an Ongoing, Randomized Study

Free
Courtney D. DiNardo, MD MSc, Andre C. Schuh, MD, Eytan M. Stein, MD, Pau Montesinos Fernandez, MD PhD, Andrew Wei, MBBS, FRACP, FRCPA, PhD, Stephane De Botton, Amer M. Zeidan, MBBS, MHS, Amir T. Fathi, MD, Lynn Quek, MD PhD, Hagop M. Kantarjian, MD, Mark G. Frattini, MD, Frederik Lersch, RN, Jing Gong, PhD, Aleksandra Franovic, PhD, Kyle MacBeth, PhD, Paresh Vyas, MD PhD, Hartmut Döhner, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 643.
https://doi.org/10.1182/blood-2019-130362
Published: 2019
Journal Articles

Antibody Dependent Enhancement of Infections after High Dose Chemotherapy

Free
Jens Magnus Bernth-Jensen, MD, Bjarne Kuno Møller, MD, Steffen Thiel, PhD, Anette Tarp Hansen, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1047.
https://doi.org/10.1182/blood-2019-122236
Published: 2019
Journal Articles

Dominant Role of αIIbβ3 in Platelet Interactions with Polymerizing Cross-Linked Fibrin

Free
Claudia Lorena Buitrago, PhD, Barry S. Coller, MD, Hina Zafar
Journal: Blood
Blood (2019) 134 (Supplement_1): 1061.
https://doi.org/10.1182/blood-2019-122753
Published: 2019
Journal Articles

High Serum VEGF Level in Erdheim-Chester Disease: Correlation with Cardiovascular Involvement and Response to Treatment

Free
Anaïs Roeser, MD, Marine Bravetti, MD, Levi-Dan Azoulay, MD, Makoto Miyara, MD, Jean-François Emile, MD, Jean Donadieu, MD PhD, Zahir Amoura, MD MSc, Fleur Cohen-Aubart, MD PhD, Julien Haroche
Journal: Blood
Blood (2019) 134 (Supplement_1): 2324.
https://doi.org/10.1182/blood-2019-129984
Published: 2019
Journal Articles

Lintuzumab Ac-225 in Combination with CLAG-M Chemotherapy in Relapsed/Refractory AML: Interim Results of a Phase I Study

Free
Sameem Abedin, MD, Guru Subramanian Guru Murthy, MBBS, Lyndsey Runaas, MD, Laura C. Michaelis, MD, Ehab L. Atallah, MD, Mehdi Hamadani, MD, Alexandra M. Harrington, MDMT(ASCP), Karen Carlson, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2605.
https://doi.org/10.1182/blood-2019-122487
Published: 2019
Journal Articles

Results from a Global Randomized Phase 3 Study of Guadecitabine (G) Vs Treatment Choice (TC) in 815 Patients with Treatment Naïve (TN) AML Unfit for Intensive Chemotherapy (IC) ASTRAL-1 Study: Analysis By Number of Cycles

Free
Gail J. Roboz, MD, Hartmut Döhner, MD, Marco Gobbi, MD, Patricia L. Kropf, MD, Jiri Mayer, MD, Jürgen Krauter, MD, Tadeusz Robak, MD, Hagop M. Kantarjian, MD, Jan Novak, MD PhD, Wieslaw Jedrzejczak, MD, Xavier Thomas, MD PhD, Mario Ojeda-Uribe, MD, Yasushi Miyazaki, MD PhD, Yoo Hong Min, MD PhD, Su-Peng Yeh, MD, Joseph M Brandwein, MD, Liana Gercheva, MD, Judit Demeter, MD, Elizabeth A. Griffiths, MD, Karen W.L. Yee, MD, Jean-Pierre Issa, MD, Yong Hao, MD PhD, Mohammad Azab, MD, Pierre Fenaux, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2591.
https://doi.org/10.1182/blood-2019-127253
Published: 2019
Journal Articles

Urine Proteomic Analysis Reveals Disease-Specific Patterns in Pediatric Patients with Classical Hodgkin's Disease(HD). an Addon Study to the Euronet-PHL-C2 Trial

Free
Karl-Walter Sykora, MD, Jochen Metzger, PhD, Dieter Körholz, MD PhD, Michael Frühwald, MD, Gabriele Strauss, MD, Norbert Jorch, MD, Jozef Zlocha, MD PhD, Thomas Wiesel, MD, Axel Sauerbrey, MD, Monika Streiter, MD, Rhoikos Furtwaengler, MD, Gunnar Cario, MD PhD, Thorsten Simon, MD PhD, Holger Christiansen, MD, Peter Vorwerk, MD, Angela Wawer, MD, Wolfram Scheurlen, MD, Hermann Müller, MD, Stefan Bielack, MD, Martin Ebinger, PD Dr. MD, Klaus-Michael Debatin, MD, Oliver Andres, MD, Christine Mauz-Körholz, Anja Troeger, MD, Dominik Schneider, MD, Eva M Weissinger, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2804.
https://doi.org/10.1182/blood-2019-125611
Published: 2019