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Journal Articles

PRMT5 Inhibition Modulates E2F1 Methylation and Gene Regulatory Networks Leading to Therapeutic Efficacy in JAK2VF Mutant MPN

Friederike Pastore, MD, Neha Bhagwat, PhDBS, Aishwarya Krishnan, Alessandro Pastore, Bing Li, MD, Robert L Bowman, PhD, Wenbin Xiao, MD PhD, Aaron D Viny, MDMS, Abdul Karzai, Anouar Zouak, Young C Park, Keith Cordner, Stephanie Braunstein, Alexander Grego, Jaanvi Mehta, Benjamin H Durham, MD, Richard P. Koche, PhD, Jesper Maag, Peggy Scherle, PhD, Kris Vaddi, PhD, Ross L. Levine, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 473.
https://doi.org/10.1182/blood-2019-127122
Published: 2019
Journal Articles

Ywhae Located on Chromosome 17p13 Promotes Myeloma Cells Proliferation Via Induction of Anti-Apoptosis and Survival Signaling Pathways

Yan Xu, MD, Mariateresa Fulciniti, PhD, Mehmet Kemal Samur, PhD, Raphael Szalat, MD, Matthew Ho, Michael A Lopez, BS, Na Li, MD, Jianhong Lin, MD MSc, Tommaso Perini, MD, Srikanth Talluri, PhD, Jiye Liu, PhD, Kenneth Wen, BS, Giada Bianchi, MD, Li Zhang, MD, Lijie Xing, MD, An Gang, MD, Liang Lin, PhD, Yu-Tzu Tai, PhD, Lugui Qiu, MD, Kenneth C Anderson, MD, Nikhil Munshi, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1755.
https://doi.org/10.1182/blood.V130.Suppl_1.1755.1755
Published: 2017
Journal Articles

p53-related protein kinase confers poor prognosis and represents a novel therapeutic target in multiple myeloma

Clinical Trials & Observations
Teru Hideshima, Francesca Cottini, Yoshihisa Nozawa, Hyuk-Soo Seo, Hiroto Ohguchi, Mehmet K. Samur, Diana Cirstea, Naoya Mimura, Yoshikazu Iwasawa, Paul G. Richardson, Nikhil C. Munshi, Dharminder Chauhan, Walter Massefski, Teruhiro Utsugi, Sirano Dhe-Paganon, Kenneth C. Anderson
Journal: Blood
Blood (2017) 129 (10): 1308–1319.
https://doi.org/10.1182/blood-2016-09-738500
Published: 2017
Includes: Supplemental data
Journal Articles

Dual Role of Pim-2 Depends on the Associated Proteome.

Daphna Levy, MSc, Amos M. Cohen, M.D., Jeremy Don, PhD
Journal: Blood
Blood (2006) 108 (11): 4334.
https://doi.org/10.1182/blood.V108.11.4334.4334
Published: 2006
Journal Articles

Challenging E2F-1 and c-Myb Block of Myeloid Terminal Differentiation with the Tumor Suppressor-Egr1.

John D. Gibbs, B.S, Alaina A. Borden, B.S, Dan A. Liebermann, Ph.D, Barbara Hoffman, Ph.D.
Journal: Blood
Blood (2004) 104 (11): 4330.
https://doi.org/10.1182/blood.V104.11.4330.4330
Published: 2004
Journal Articles

Transcription activation function of C/EBPα is required for induction of granulocytic differentiation

Karen Keeshan, Giorgia Santilli, Francesca Corradini, Danilo Perrotti, Bruno Calabretta
Journal: Blood
Blood (2003) 102 (4): 1267–1275.
https://doi.org/10.1182/blood-2003-02-0477
Published: 2003
Journal Articles

Overexpression of E2F-1 leads to cytokine-independent proliferation and survival in the hematopoietic cell line BaF-B03

Salvador Gala, Alexandra Marreiros, Graeme J. Stewart, Peter Williamson
Journal: Blood
Blood (2001) 97 (1): 227–234.
https://doi.org/10.1182/blood.V97.1.227
Published: 2001
Journal Articles

Deregulated E2F-1 blocks terminal differentiation and loss of leukemogenicity of M1 myeloblastic leukemia cells without abrogating induction of p15 INK4B and p16 INK4A

Arshad Amanullah, Barbara Hoffman, Dan A. Liebermann
Journal: Blood
Blood (2000) 96 (2): 475–482.
https://doi.org/10.1182/blood.V96.2.475
Published: 2000
Journal Articles

Increased proteasome degradation of cyclin-dependent kinase inhibitor p27 is associated with a decreased overall survival in mantle cell lymphoma

Roberto Chiarle, Leo M. Budel, Jeffrey Skolnik, Glauco Frizzera, Marco Chilosi, Alessandra Corato, Gianni Pizzolo, Jory Magidson, Alessia Montagnoli, Michele Pagano, Brigitte Maes, Christine De Wolf-Peeters, Giorgio Inghirami
Journal: Blood
Blood (2000) 95 (2): 619–626.
https://doi.org/10.1182/blood.V95.2.619
Published: 2000
Journal Articles

MDM2 Protein Overexpression Promotes Proliferation and Survival of Multiple Myeloma Cells

Gerrard Teoh, Mitsuyoshi Urashima, Atsushi Ogata, Dharminder Chauhan, James A. DeCaprio, Steven P. Treon, Robert L. Schlossman, Kenneth C. Anderson
Journal: Blood
Blood (1997) 90 (5): 1982–1992.
https://doi.org/10.1182/blood.V90.5.1982
Published: 1997