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Journal Articles

Relapse risk following truncation of pegylated asparaginase in childhood acute lymphoblastic leukemia

Clinical Trials & Observations
Sofie Gottschalk Højfeldt, Kathrine Grell, Jonas Abrahamsson, Bendik Lund, Kim Vettenranta, Ólafur G. Jónsson, Thomas L. Frandsen, Benjamin O. Wolthers, Hanne Vibeke Marquart, Goda Vaitkeviciene, Kristi Lepik, Mats Heyman, Kjeld Schmiegelow, Birgitte Klug Albertsen
Journal: Blood
Blood (2021) 137 (17): 2373–2382.
https://doi.org/10.1182/blood.2020006583
Published: 2021
Includes: Supplemental data
Journal Articles

Thromboembolism prophylaxis in adult patients with acute lymphoblastic leukemia treated in the GRAALL-2005 study

CME Clinical Trials & Observations
Corentin Orvain, Marie Balsat, Emmanuelle Tavernier, Jean-Pierre Marolleau, Thomas Pabst, Patrice Chevallier, Noémie de Gunzburg, Victoria Cacheux, Françoise Huguet, Sylvain Chantepie, Denis Caillot, Yves Chalandon, Jamilé Frayfer, Caroline Bonmati, Véronique Lheritier, Norbert Ifrah, Hervé Dombret, Nicolas Boissel, Mathilde Hunault-Berger
Journal: Blood
Blood (2020) 136 (3): 328–338.
https://doi.org/10.1182/blood.2020004919
Published: 2020
Includes: Supplemental data
Journal Articles

Reduced–dose intensity therapy for pediatric lymphoblastic leukemia: long-term results of the Recife RELLA05 pilot study

Clinical Trials & Observations
Francisco Pedrosa, Elaine Coustan-Smith, Yinmei Zhou, Cheng Cheng, Arli Pedrosa, Mecneide Mendes Lins, Marcia Pedrosa, Norma Lucena-Silva, Alessandra Maria de Luna Ramos, Ester Vinhas, Gaston K. Rivera, Dario Campana, Raul C. Ribeiro
Journal: Blood
Blood (2020) 135 (17): 1458–1466.
https://doi.org/10.1182/blood.2019004215
Published: 2020
Includes: Supplemental data
Journal Articles

How I treat the toxicities of pegasparaginase in adults with acute lymphoblastic leukemia

Ibrahim Aldoss, Dan Douer
Journal: Blood
Blood (2020) 135 (13): 987–995.
https://doi.org/10.1182/blood.2019002477
Published: 2020
Journal Articles

How I treat newly diagnosed T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma in children

Clinical Trials & Observations
David T. Teachey, David O’Connor
Journal: Blood
Blood (2020) 135 (3): 159–166.
https://doi.org/10.1182/blood.2019001557
Published: 2020
Journal Articles

Predicting success of desensitization after pegaspargase allergy

Clinical Trials & Observations
Hope D. Swanson, John C. Panetta, Patricia J. Barker, Yiwei Liu, Hiroto Inaba, Mary V. Relling, Ching-Hon Pui, Seth E. Karol
Journal: Blood
Blood (2020) 135 (1): 71–75.
https://doi.org/10.1182/blood.2019003407
Published: 2020
Includes: Supplemental data
Journal Articles

Risk of Thrombosis in Adult Philadelphia-Positive ALL Treated with an Asparaginase-Free Pediatric-Inspired ALL Regimen with Imatinib

Ruiqi Chen, MSc, Xing Liu, PharmD, Solaf Kanfar, MD, Dawn Maze, MDFRCPC,MSc, Steven M Chan, MD PhD, Vikas Gupta, MD FRCP, FRCPath, Karen W.L. Yee, MD, Mark D. Minden, MD PhD, Aaron D Schimmer, MD PhD, Andre C. Schuh, MD, Caroline J McNamara, MBBS, Tracy Murphy, MDFRCP,FRCPath, Anna Xu, Umberto Falcone, MD, Jack Seki, PharmD, Hassan Sibai, MBBS
Journal: Blood
Blood (2019) 134 (Supplement_1): 1303.
https://doi.org/10.1182/blood-2019-124117
Published: 2019
Journal Articles

Successful Toxicity Reduction in Ma-Spore ALL 2010 in Standard/Intermediate Risk Childhood ALL: Replacing Cytarabine/Doxorubicin with More Vincristine and L-Asparaginase during Consolidation and Delayed Intensification

Bernice Oh, MBBS, MRCP, Shawn Lee, MD, Zelia Seeto, Germaine Liew, Bsc, Edwynn Chiew, MBBS, Zhi Wei Chen, Bsc, Yiong Huak Chan, PhD, Jing Jia Eng, Bsc, Koon Mian Foo, Bsc, Ching Mei Joyce Lam, MD, Ah Moy Tan, MD, Allen Eng Juh Yeoh, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1307.
https://doi.org/10.1182/blood-2019-122098
Published: 2019
Journal Articles

Outcomes in Older Adults with Acute Lymphoblastic Leukemia (ALL) Receiving Linker Protocol at a Single Center Institution

Cindy Lynn Hickey, MDFRCPC, David Conrad, MD PhD, Stephen Couban, MDBSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 1308.
https://doi.org/10.1182/blood-2019-121336
Published: 2019
Journal Articles

Post-Remission Treatment with Chemotherapy or Allogeneic Hematopoietic Stem Cell Transplantation (alloHSCT) in Adult Patients with High-Risk (HR) Philadelphia Chromosome-Negative (Ph-neg) Acute Lymphoblastic Leukemia (ALL) According to Their Minimal Residual Disease (MRD). Final Results of the Pethema ALL-HR-11 Trial

Josep-Maria Ribera, MD PhD, Mireia Morgades, M.Prob.S, Juana Ciudad, PhD, Pau Montesinos, MD PhD, Pere Barba, MD PhD, Irene García-Cadenas, María José Moreno, MD, Susana Vives, MD, Jordi Esteve, Cristina Gil, Silvia Monsalvo, MD, María Teresa Artola, MD, Jordi Ribera, PhD, Eulàlia Genescà, PhD, Mar Tormo, MD PhD, Marta Cervera, MD, Daniel Martínez-Carballeira, MD, Andrés Novo, MD, José González-Campos, MD, Beatriz Soria, MD, Arancha Bermúdez, MD, Aurelio López Martínez, MD, Santiago Mercadal, MD, Rosa Fernández-Martín, MD, Rosa Coll, MD, Josefina Serrano, Maria Luz Amigo, MD, Pilar Martínez-Sánchez, Juan-Miguel Bergua, MD, Alfons Serrano-Maestro, MD, Alberto Giménez Conca, MD, Susana Barrena, PhD, Isabel Granada, PhD, Evarist Feliu, MD PhD, Alberto Orfao, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 826.
https://doi.org/10.1182/blood-2019-123613
Published: 2019
Journal Articles

First Analysis of the UKALL14 Phase 3 Randomised Trial to Determine If the Addition of Rituximab to Standard Induction Chemotherapy Improves EFS in Adults with Precursor B-ALL (CRUK/09/006)

David I Marks, MBBS, PhD FRCPath, Amy A. Kirkwood, MSc, Clare J Rowntree, MBBS, PhD FRCP, FRCPath, Melanie Aguiar, BSc, Katharine E Bailey, MBBS, FRCPath, MA, MRCP, Brendan Beaton, MD, Laura Clifton-Hadley, PhDBSc, Emma Lawrie, BSc, SooWah Lee, MSc, Andrew K McMillan, FRCP, Anthony V. Moorman, PhD, Rachel J. Mitchell, MSc, Pip Patrick, PhDMSc,MA, Tobias F Menne, MD PhD FRCPath, Paul Smith, Bela Wrench, MBBS, MD MRCP, FRCPath, Krisztina Zuborne Alapi, MSc, Adele K. Fielding, MBBS,PhDFRCP,FRCPath
Journal: Blood
Blood (2019) 134 (Supplement_1): 739.
https://doi.org/10.1182/blood-2019-123374
Published: 2019
Journal Articles

Intensive Chemotherapy for High-Risk ALL in Children - the Nordic Collaborative Approach

Atte Nikkilä, MD, Olli Lohi, MD PhD, Ólafur Gísli Jónsson, MD PhD, Bendik Lund, MD PhD, Jonas Abrahamsson, Goda Elizabeta Vaitkeviciene, MD PhD, Kaie Pruunsild, MD, Mats Heyman, MD PhD, Hanne Vibeke Marquart, MD PhD, Kim Vettenranta, MD PhD, Kjeld Schmiegelow, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 742.
https://doi.org/10.1182/blood-2019-122914
Published: 2019
Journal Articles

A Modified CALGB-10403 in Hispanic Adolescent and Young Adults with Philadelphia -Negative Acute Lymphoblastic Leukemia: Promising Results Despite a High-Rate of Metabolic and Hepatic Toxicities

Juan Rangel-Patiño, MD, Alvaro Cabrero Garcia, Carolina Balderas-Delgado, MD, Lauro Fabian Amador, MD, Yvette Neme Yunes, Ana Cooke, MD, Adriana Rosas, Roberta Demichelis, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1352.
https://doi.org/10.1182/blood-2019-126108
Published: 2019
Journal Articles

Clinical Outcome of an Multicentre, Randomized, Phase II Clinical Trial for Patients with Extranodal NK/T Cell Lymphoma Treated By P-Gemox or Aspametdex

Hui-qiang Huang, Gao Yan, Hang Su, Yunhong Huang, Yuhuan Gao, Wang Xiaoxiao, Bai Bing, Yujing Zhang, Liping Su, Xiaoxia Chu, Wenyu Li, MD PhD, Junyi Zhang, Qiaohua Zhang, MD, Liansheng Zhang, Xiaohua Hu, Liqun Zou, Zhiming Li, Wenqi Jiang
Journal: Blood
Blood (2019) 134 (Supplement_1): 1569.
https://doi.org/10.1182/blood-2019-123478
Published: 2019
Journal Articles

Asian Experience of Treating Venous Thromboembolism in Patients with Acute Leukaemia

Cheryl XQ Lim, MBBS, M MD(Int MD, MRCP, Priscella Shirley Chia, BSc, Eng Soo Yap, MBBS, M MD(Int MD, MRCP, FRCPath Haematology
Journal: Blood
Blood (2019) 134 (Supplement_1): 1161.
https://doi.org/10.1182/blood-2019-130041
Published: 2019
Journal Articles

Separate Roles of Asparagine and Glutamine in Cytostatic Effect of L-Asparaginase - Stable Isotope Tracing Approach

Katerina Hlozkova, PhD, Alpesh Thakker, PhD, Natividad Alquézar-Artieda, Marketa Zaliova, MD PhD, Jan Trka, Prof., MD PhD, Daniel A Tennant, PhD, Julia Starkova, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2575.
https://doi.org/10.1182/blood-2019-127911
Published: 2019
Journal Articles

Major Deviations in the Delivery of Induction Chemotherapy Are Associated with an Increased Risk of Relapse in Acute Lymphoblastic Leukaemia: Results from UKALL2003

Rachael E Hough, MD, Amy A Kirkwood, Sujith Samarasinghe, Clare J Rowntree, MBBS, PhD FRCP, FRCPath, Nicholas John Goulden, MD PhD MRCPath, Ajay Vora
Journal: Blood
Blood (2019) 134 (Supplement_1): 2579.
https://doi.org/10.1182/blood-2019-127223
Published: 2019
Journal Articles

Flow-Cytometry Based Detection of Any Minimal Residual Disease (FC-MRD) in Children with T-Acute Lymphoblastic Leukemias (T-ALL) Is a Powerful Indicator of Outcome

Prashant Tembhare, MD, Gaurav Narula, MD, Gaurav Chatterjee, MD, Twinkle Khanka, Mahima Sanyal, Sitaram Ghogale, Nikhil Patkar, MD, Nilesh Deshpande, Yajamanam Badrinath, Sumeet Gujral, MD, Shripad Banavali, MD, Papagudi Ganesan Subramanian, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2585.
https://doi.org/10.1182/blood-2019-128347
Published: 2019
Journal Articles

Open-Label, Multicenter, Phase 2/3 Study of Recombinant Crisantaspase Produced in Pseudomonas Fluorescens ( RC-P) in Patients with Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LBL) Following Hypersensitivity to Escherichia coli -Derived Asparaginases

Luke Maese, DO, Rachel E. Rau, MD, Elizabeth A. Raetz, MD, Tong Lin, Jin Zhu, Pil Kim, Reddy Chandula, Sherrie McClung, Julie Gray, Mi Rim Choi, MD, Mignon L. Loh, MD, Peter C. Adamson
Journal: Blood
Blood (2019) 134 (Supplement_1): 2586.
https://doi.org/10.1182/blood-2019-123710
Published: 2019
Journal Articles

Safety, Efficacy, and PK of the BCL2 Inhibitor Venetoclax in Combination with Chemotherapy in Pediatric and Young Adult Patients with Relapsed/Refractory Acute Myeloid Leukemia and Acute Lymphoblastic Leukemia: Phase 1 Study

Seth E Karol, MD, Todd M Cooper, DO, Henrique Bittencourt, Lia Gore, MD, Maureen M O'Brien, MD, Christopher Fraser, MD, Marion Gambart, MD, Gunnar Cario, MD PhD, Christian Michel Zwaan, MD PhD, Jean-Pierre Bourquin, MD PhD, Mignon L. Loh, MD, Hubert Caron, MD PhD, Betty Prine, Ahmed Hamed Salem, PhD FCP, Kristina Unnebrink, Bo Tong, PhD, Tammy Palenski, PhD, Andrew E. Place, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2649.
https://doi.org/10.1182/blood-2019-129805
Published: 2019