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Journal Articles

AML Immunotherapy Using a Novel Tcrm-Based Bispecific Antibody That Targets a Leader Sequence Peptide Derived from Cathepsin G

Chunhua Shi, Ze Tian, Jun Yan, Mao Zhang, Pariya Sukhumalchandra, Edward Chang, Guojun Yang, Junping You, Meng Cui, Qing Shi, Anne Philips, Na Qiao, Anna Sergeeva, Lisa St. John, Hong He, Dongxing Zha, Jeffrey J. Molldrem, Gheath Alatrash
Journal: Blood
Blood (2023) 142 (Supplement 1): 1415.
https://doi.org/10.1182/blood-2023-189514
Published: 2023
Journal Articles

Targeting Myeloid Leukemia Using Novel TCR-like Chimeric Antigen Receptor-T Cells Against Cathepsin G

Jun Yan, Ze Tian, Chunhua Shi, Mao Zhang, Pariya Sukhumalchandra, Guojan Yang, Qing Edward Chang, Junping You, Meng Cui, Qing Shi, Anne Philip, Na Qiao, Anna Sergeeva, Lisa St John, Hong He, Dongxing Zha, Jeffrey J. Molldrem, Gheath Alatrash
Journal: Blood
Blood (2022) 140 (Supplement 1): 7392–7393.
https://doi.org/10.1182/blood-2022-166488
Published: 2022
Journal Articles

Phase 1 Trial Testing Single Agent CUDC-907, a Novel, Oral Dual Inhibitor of Histone Deacetylase (HDAC) and PI3K: Initial Assessment of Patients with Relapsed or Refractory (RR) Diffuse Large B-Cell Lymphoma (DLBCL), Including Double Expressor (DE) Lymphoma

Anas Younes, MD, Jesus G. Berdeja, MD, Manish R. Patel, MD, Kevin R. Kelly, MD PhD, Ian W. Flinn, MD PhD, John F Gerecitano, MD PhD, Sattva S. Neelapu, MD, Amanda R. Copeland, RN, MSN, CNS, Amy Akins, RN, BSN, CCRC, Myles Clancy, Anna Ma, MS, Kaiming Sun, PhD, Ze Tian, PhD, Jing Wang, PhD, Jaye Viner, MD MPH, Yasuhiro Oki, MD
Journal: Blood
Blood (2015) 126 (23): 257.
https://doi.org/10.1182/blood.V126.23.257.257
Published: 2015
Journal Articles

Anti-Myeloma Activity of a Novel Free Radical Inducer Rrx-001

Deepika Sharma Das, PhD, Ze Tian, PhD, Arghya Ray, PhD, Durgadevi Ravillah, PhD, Yan Song, PhD, Paul G. Richardson, Bryan Oronsky, MD, Jan Scicinski, PhD, Dharminder Chauhan, PhD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2014) 124 (21): 4712.
https://doi.org/10.1182/blood.V124.21.4712.4712
Published: 2014
Journal Articles

A novel small molecule inhibitor of deubiquitylating enzyme USP14 and UCHL5 induces apoptosis in multiple myeloma and overcomes bortezomib resistance

Ze Tian, Padraig D’Arcy, Xin Wang, Arghya Ray, Yu-Tzu Tai, Yiguo Hu, Ruben D. Carrasco, Paul Richardson, Stig Linder, Dharminder Chauhan, Kenneth C. Anderson
Journal: Blood
Blood (2014) 123 (5): 706–716.
https://doi.org/10.1182/blood-2013-05-500033
Published: 2014
Includes: Supplemental data
Journal Articles

SL-401, A Novel Targeted Therapy Directed To The Interleukin-3 Receptor (IL-3R), Inhibits Plasmacytoid Dendritic Cell (pDC)-Induced Myeloma Cell Growth and Overcomes Drug Resistance

Arghya Ray, Ph.D, Deepika Sharma Das, Ph.D., Ze Tian, Ph.D, Vincent Macri, Christopher L. Brooks, PhD, Paul G. Richardson, MD, Eric Rowinsky, MD, Dharminder Chauhan, PhD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2013) 122 (21): 3170.
https://doi.org/10.1182/blood.V122.21.3170.3170
Published: 2013
Journal Articles

A Novel Small Molecule Inhibitor Of Deubiquitylating Enzyme USP14 and UCHL5 Induces Apoptosis In Myeloma Cells and Overcomes Bortezomib Resistance

Ze Tian, Ph.D, Padraig D'Arcy, Ph.D, Xin Wang, Ph.D, Arghya Ray, Yu-Tzu Tai, PhD, Yiguo Hu, PhD, Ruben Carrasco, MD, PhD, Deepika Das, Ph.D, Paul Richardson, MD, Stig Linder, MD, PhD, Dharminder Chauhan, PhD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2013) 122 (21): 1923.
https://doi.org/10.1182/blood.V122.21.1923.1923
Published: 2013
Journal Articles

Investigational agent MLN9708/2238 targets tumor-suppressor miR33b in MM cells

Ze Tian, Jian-jun Zhao, Yu-Tzu Tai, Samir B. Amin, Yiguo Hu, Allison J. Berger, Paul Richardson, Dharminder Chauhan, Kenneth C. Anderson
Journal: Blood
Blood (2012) 120 (19): 3958–3967.
https://doi.org/10.1182/blood-2012-01-401794
Published: 2012
Includes: Supplemental data
Journal Articles

Investigational Agent MLN9708 Target Tumor Suppressor MicroRNA-33b in Multiple Myeloma Cells

Ze Tian, Jian-Jun Zhao, Jianhong Lin, PhD, Dharminder Chauhan, PhD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2011) 118 (21): 136.
https://doi.org/10.1182/blood.V118.21.136.136
Published: 2011
Journal Articles

An Investigational Novel Orally Bioavailable Proteasome Inhibitor MLN9708/MLN2238 Triggers Cytotoxicity In Multiple Myeloma Cells Via p21- and Caspase-8-Dependent Signaling Pathway

Dharminder Chauhan, PhD, Ze Tian, Teru Hideshima, Nikhil C. Munshi, Paul G Richardson, Kenneth C. Anderson
Journal: Blood
Blood (2010) 116 (21): 2992.
https://doi.org/10.1182/blood.V116.21.2992.2992
Published: 2010
Journal Articles

Deubiquitylating Enzyme USP-7, a Novel Therapeutic Target in Multiple Myeloma.

Dharminder Chauhan, Ph.D, Ze Tian, Ph.D, Benjamin Nicholson, Bin Zhou, Teru Hideshima, Nikhil Munshi, Paul Richardson, Kenneth C. Anderson
Journal: Blood
Blood (2009) 114 (22): 610.
https://doi.org/10.1182/blood.V114.22.610.610
Published: 2009
Journal Articles

HDAC Inhibition by LBH589 Affects Phenotype and Function of Human Dendritic Cells.

Weihua Song, MD, Yu-Tzu Tai, Ph.D., Ze Tian, Ph.D, Teru Hideshima, M.D., Ph.D., Dharminder Chauhan, Ph.D, Puru Nanjappa, MS, Mark A. Exley, Ph.D, Kenneth C. Anderson, MD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2009) 114 (22): 1646.
https://doi.org/10.1182/blood.V114.22.1646.1646
Published: 2009