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Yan-Ou Yang
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Journal Articles

Selective targeting of mutated calreticulin by the monoclonal antibody INCA033989 inhibits oncogenic function of MPN

Edimara S. Reis, Rebecca Buonpane, Hamza Celik, Caroline Marty, Angela Lei, Fatoumata Jobe, Mark Rupar, Yue Zhang, Darlise DiMatteo, Rahel Awdew, Bianca L. Ferreira, Lynn Leffet, Lu Lu, Elodie Rosa, Maxime Evrard, Gaurang Trivedi, Brittney Wass, April Horsey, Xin He, Maryanne Covington, Alla Volgina, Florence Pasquier, Laurence Legros, Guillemette Fouquet, William Vainchenker, Yan-ou Yang, Breann Barker, Jing Zhou, Shaun Stewart, Ian S. Hitchcock, Dashyant Dhanak, Ricardo Macarron, Isabelle Plo, Horacio Nastri, Patrick A. Mayes
Journal: Blood
Blood (2024) 144 (22): 2336–2348.
https://doi.org/10.1182/blood.2024024373
Published: 2024
Includes: Supplemental data
Journal Articles

Exposure-Response Relationships for Axatilimab, a Humanized Monoclonal Antibody Targeting CSF-1R, in Patients with Chronic Graft-Versus-Host Disease

Yan-ou Yang, Alina Volkova, Victor Sokolov, Xing Liu, Cristina Leon, Yuri Kosinsky, Jennifer Sheng, Xuejun Chen
Journal: Blood
Blood (2024) 144 (Supplement 1): 2140.
https://doi.org/10.1182/blood-2024-194594
Published: 2024
Journal Articles

Phase 1/2 Study of the Activin Receptor-like Kinase-2 Inhibitor Zilurgisertib (INCB000928, LIMBER-104) As Monotherapy or with Ruxolitinib in Patients with Anemia Due to Myelofibrosis

Sanjay Mohan, Stephen Oh, Jean-Jacques Kiladjian, Masahiro Takeuchi, Jason Gotlib, Ellen K. Ritchie, Taizo Shimomura, Paola Guglielmelli, Anthony M. Hunter, Francesca Palandri, Francoise Boyer, Alessandro Rambaldi, Takehiko Mori, Tomoki Ito, Betty Lamothe, Yan-Ou Yang, Yi Cui, Francis Seguy, Amanda McBride, Prithviraj Bose
Journal: Blood
Blood (2023) 142 (Supplement 1): 624.
https://doi.org/10.1182/blood-2023-179291
Published: 2023
Journal Articles

Characterization of INCB00928, a Potent and Selective ALK2 Inhibitor for the Treatment of Anemia

Yaoyu Chen, Matthew C. Stubbs, PhD, Michelle Pusey, Xiaoming Wen, Robert J. Collins, Kanishk Kapilashrami, Mark Rupar, Pramod Thekkat, Luping Lin, PhD, Kevin Bowman, Yan-ou Yang, Sharon Diamond, Swamy Yeleswaram, PhD, Sunkyu Kim, Holly K. Koblish, PhD, Yingnan Chen, Susan Wee, PhD BS
Journal: Blood
Blood (2020) 136 (Supplement 1): 52.
https://doi.org/10.1182/blood-2020-136138
Published: 2020
Journal Articles

LSD1 Inhibition Induces Fetal Hemoglobin Expression and Provides a Novel Therapeutic Approach to Sickle Cell Disease

Sang Hyun Lee, PhD, Maxim Soloviev, MDPhD, Yan Zhang, PhD, Valerie Roman, Gengjie Yang, Kevin Bowman, Krista Burke, Alexander Margulis, Sybil O'Connor, Yan-ou Yang, PhD, Liangxing Wu, PhD, Richard Wynn, PhD, Timothy Burn, PhD, Dana Shuey, PhD, Sharon Diamond, PhD, Wenqing Yao, PhD, Gregory Hollis, PhD, Swamy Yeleswaram, PhD, Alan Roberts, PhD, Reid Huber, PhD, Peggy Scherle, PhD, Bruce Ruggeri, PhD
Journal: Blood
Blood (2016) 128 (22): 2472.
https://doi.org/10.1182/blood.V128.22.2472.2472
Published: 2016