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Ricardo Macarron
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Journal Articles

Selective targeting of mutated calreticulin by the monoclonal antibody INCA033989 inhibits oncogenic function of MPN

Edimara S. Reis, Rebecca Buonpane, Hamza Celik, Caroline Marty, Angela Lei, Fatoumata Jobe, Mark Rupar, Yue Zhang, Darlise DiMatteo, Rahel Awdew, Bianca L. Ferreira, Lynn Leffet, Lu Lu, Elodie Rosa, Maxime Evrard, Gaurang Trivedi, Brittney Wass, April Horsey, Xin He, Maryanne Covington, Alla Volgina, Florence Pasquier, Laurence Legros, Guillemette Fouquet, William Vainchenker, Yan-ou Yang, Breann Barker, Jing Zhou, Shaun Stewart, Ian S. Hitchcock, Dashyant Dhanak, Ricardo Macarron, Isabelle Plo, Horacio Nastri, Patrick A. Mayes
Journal: Blood
Blood (2024) 144 (22): 2336–2348.
https://doi.org/10.1182/blood.2024024373
Published: 2024
Includes: Supplemental data
Journal Articles

ALK2 and JAK2 Inhibition for Improved Treatment of Anemia in Myelofibrosis Patients: Preclinical Profile of an ALK2 Inhibitor Zilurgisertib in Combination with Ruxolitinib

Matthew C. Stubbs, Michelle Pusey, Xiaoming Wen, Katherine Drake, Nina Zolotarjova, Amanda Smith, Maryanne Covington, Guofeng Zhang, Ricardo Macarrón, Sunkyu Kim
Journal: Blood
Blood (2023) 142 (Supplement 1): 1789.
https://doi.org/10.1182/blood-2023-181055
Published: 2023
Journal Articles

Preclinical Evaluation of INCB160058 - a Novel and Potentially Disease-Modifying Therapy for JAK2V617F Mutant Myeloproliferative Neoplasms

Matthew C. Stubbs, Hamza Celik, Yanran Ai, Xin He, Hong Chang, Angela Lei, Mark Rupar, Brittney Wass, Melody Diamond, Xiaoming Wen, Jun Li, Nina Zolotarjova, Alex Margulis, Gaurang Trivedi, Angelo B.A. Laranjeira, Cooper A. Taylor, Jennifer Rocha, Christoph Pollmann, Jacob Piehler, Bianca L. Ferreira, Ian Hitchcock, Ricardo Macarrón, Eddy W. Yue, Sunkyu Kim
Journal: Blood
Blood (2023) 142 (Supplement 1): 860.
https://doi.org/10.1182/blood-2023-179369
Published: 2023
Journal Articles

Comparison of the Enzymatic and Cellular Profiles of Clinical JAK2 Inhibitors for the Treatment of Myelofibrosis

Hamza Celik, Maryanne Covington, Katherine Drake, Kamna Katiyar, Alex Margulis, Amanda Smith, Gaurang Trivedi, Brittney Wass, Guofeng Zhang, Nina Zolotarjova, Sunkyu Kim, Ricardo Macarrón
Journal: Blood
Blood (2023) 142 (Supplement 1): 4532.
https://doi.org/10.1182/blood-2023-174917
Published: 2023
Journal Articles

Establishment of Human Bone Marrow-on-Chip As a Preclinical Model to Evaluate Drug-Induced Toxicities and Myelofibrosis Patient-Specific Pathophysiology

Manti Guha, Ronald Dove, Aragaw Gebeyehu, Daniel Merenich, Paul Collier, Erin L. Crowgey, Mike Schaffer, Dana Shuey, Ricardo Macarrón, Alejandro Amador Arjona
Journal: Blood
Blood (2023) 142 (Supplement 1): 5611.
https://doi.org/10.1182/blood-2023-180166
Published: 2023