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Tanya Rapoz-D’Silva
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Journal Articles

Focal deletions of a promoter tether activate the IRX3 oncogene in T-cell acute lymphoblastic leukemia

Sunniyat Rahman, Gianna Bloye, Nadine Farah, Jonas Demeulemeester, Joana R. Costa, David O’Connor, Rachael Pocock, Tanya Rapoz-D’Silva, Adam Turna, Lingyi Wang, SooWah Lee, Adele K. Fielding, Juliette Roels, Roman Jaksik, Małgorzata Dawidowska, Pieter Van Vlierberghe, Suzana Hadjur, Jim R. Hughes, James O. J. Davies, Alejandro Gutierrez, Michelle A. Kelliher, Peter Van Loo, Mark A. Dawson, Marc R. Mansour
Journal: Blood
Blood (2024) 144 (22): 2319–2326.
https://doi.org/10.1182/blood.2024024300
Published: 2024
Includes: Supplemental data
Journal Articles

Molecular, clinical, and therapeutic determinants of outcome in NPM1 -mutated AML

Clinical Trials & Observations
Jad Othman, Nicola Potter, Adam Ivey, Yanis Tazi, Elli Papaemmanuil, Jelena Jovanovic, Sylvie D. Freeman, Amanda Gilkes, Rosemary Gale, Tanya Rapoz-D’Silva, Manohursingh Runglall, Michelle Kleeman, Pawan Dhami, Ian Thomas, Sean Johnson, Joanna Canham, Jamie Cavenagh, Panagiotis Kottaridis, Claire Arnold, Hans Beier Ommen, Ulrik Malthe Overgaard, Mike Dennis, Alan Burnett, Charlotte Wilhelm-Benartzi, Brian Huntly, Nigel H. Russell, Richard Dillon
Journal: Blood
Blood (2024) 144 (7): 714–728.
https://doi.org/10.1182/blood.2024024310
Published: 2024
Includes: Supplemental data
Journal Articles

The Hematopoietic Transcription Factor GATA3 Is the Main Activator of Enhancer-Mediated Activation of Oncogenic TAL1 in T-ALL

Joana R Costa, David O'Connor, Nurkaiyisah Anuar, Sunniyat Rahman, Nivedita Singh, Zhaodong China, Tanya Rapoz-D'Silva, Yang Li, Kent Fung, Sara Hyseni, Stephen Henderson, George Morrow, Yanping Guo, Javier Herrero, Richard Jenner, Dennis Keppei, A. Thomas Look, Marc R. Mansour
Journal: Blood
Blood (2022) 140 (Supplement 1): 3046–3047.
https://doi.org/10.1182/blood-2022-166396
Published: 2022
Journal Articles

Anti-CCR9 chimeric antigen receptor T cells for T-cell acute lymphoblastic leukemia

Paul M. Maciocia, Patrycja A. Wawrzyniecka, Nicola C. Maciocia, Amy Burley, Thaneswari Karpanasamy, Sam Devereaux, Malika Hoekx, David O’Connor, Theresa Leon, Tanya Rapoz-D’Silva, Rachael Pocock, Sunniyat Rahman, Giuseppe Gritti, Diana C. Yánez, Susan Ross, Tessa Crompton, Owen Williams, Lydia Lee, Martin A. Pule, Marc R. Mansour
Journal: Blood
Blood (2022) 140 (1): 25–37.
https://doi.org/10.1182/blood.2021013648
Published: 2022
Includes: Supplemental data
Journal Articles

Anti-CCR9 CAR-T Cells for T Acute Lymphoblastic Leukemia

Paul M Maciocia, Patrycja Wawrzyniecka, Nicola C Maciocia, Amy Burley, David O'Connor, Theresa E. Leon, Tanya Rapoz-D'Silva, Thaneswari Karpanasamy, Martin Pule, Marc R. Mansour
Journal: Blood
Blood (2021) 138 (Supplement 1): 903.
https://doi.org/10.1182/blood-2021-146565
Published: 2021
Journal Articles

Synthetic Lethal Screening Identifies CHK1 Inhibition As an Exploitable Vulnerability in EZH2 Deficient T-ALL

Theresa E. Leon, PhD MSc, BSc, Tanya Rapoz-D'Silva, BSc, MSc, Sunniyat Rahman, MBiochem, DIC, PhD, Michael Magnussen, BSc, MSc, Nadine Farah, MBBChir, MA, MRCP, FRCPath, Jose A. Guerra-Assunção, BSc, PhD, Rajeev Gupta, MB.ChB, PhD FRCP, FRCPath, Elisabeth P. Nacheva, MD PhD, Javier Herrero, PhD, David C. Linch, FRCP, Marc R. Mansour, MD PhD FRCPath
Journal: Blood
Blood (2017) 130 (Supplement 1): 1325.
https://doi.org/10.1182/blood.V130.Suppl_1.1325.1325
Published: 2017