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Journal Articles

Real-world use of oral iptacopan monotherapy in paroxysmal nocturnal hemoglobinuria

Blood (2025) 146 (Supplement 1): 1427.

https://doi.org/10.1182/blood-2025-1427

Published: 2025

Journal Articles

Molecular gene panel analysis in aplastic anaemia: Diagnostic utility and clinical implications

Francesco Versino, Roochi Trikha, Joanna Large, Guy Hannah, Steve Best, Shreyans Gandhi, Luke Ficinski, Paul Inocencio, Ana Olivera, Jianne Miran, Kar Lok Kong, Austin Kulasekararaj

Blood (2025) 146 (Supplement 1): 1711.

https://doi.org/10.1182/blood-2025-1711

Published: 2025

Journal Articles

Switching between complement inhibitors in patients with PNH: A real-world analysis of strategy, efficacy, and safety.

Morag Griffin, Bruno Fattizzo, Jong Wook Lee, Richard Kelly, Roochi Trikha, Yasutaka Ueda, Jun-ichi Nishimura, Christopher Patriquin, Alexander Röth, Petra Muus, Jens Panse, Miguel Gómez Álvarez, Alexandra Pike, Talha Munir, Shreyans Gandhi, Austin Kulasekararaj

Blood (2025) 146 (Supplement 1): 1114.

https://doi.org/10.1182/blood-2025-1114

Published: 2025

Journal Articles

Consistent benefits of pegcetacoplan treatment in PNH patients with and without a history of aplastic anemia in real world: Analysis of the ongoing COMPLETE Phase IV observational study

Roochi Trikha, Lenka Mastikova, Carmen Gonzalez-Gonzalez, Anna-Elina Lehtinen, Elena Surova, Shamil Sadikhov, Michael O'Malley, Regis Peffault De Latour

Blood (2025) 146 (Supplement 1): 1113.

https://doi.org/10.1182/blood-2025-1113

Published: 2025

Journal Articles

6pLOH as a marker of immune-mediated bone marrow failure: Insights from a large single center experience

Francesco Versino, Roochi Trikha, Joanna Large, Henry Wood, Azim Mohamedali, Kar Lok Kong, Shreyans Gandhi, Austin Kulasekararaj

Blood (2025) 146 (Supplement 1): 3194.

https://doi.org/10.1182/blood-2025-3194

Published: 2025

Journal Articles

Improved outcomes following allogeneic hematopoietic stem cell transplantation in patients with DDX41-mutated myeloid neoplasms: A prospective analysis of survival, GVHD, and transplant-related mortality

Shreyas Hanmantgad, Alan Mitchell, Kayleigh Mccloskey, James Aries, Francesco Versino, Roochi Trikha, Shreyans Gandhi, Madson Correia De Farias, Maria Cuadrado, Mili Shah, Varun Mehra, Pramila Krishnamurthy, Michelle Kenyon, Victoria Potter, Austin Kulasekararaj

Blood (2025) 146 (Supplement 1): 6083.

https://doi.org/10.1182/blood-2025-6083

Published: 2025

Journal Articles

Paroxysmal nocturnal hemoglobinuria in pediatric patients: A UK experience

Morag Griffin, Malinthi Adikarama, Shreyans Gandhi, Petra Muus, Alexandra Pike, Talha Munir, Matthew Holt, Louise Arnold, Franceso Versino, Joanna Large, Richard Kelly, Austin Kulasekararaj, Roochi Trikha

Blood (2025) 146 (Supplement 1): 4662.

https://doi.org/10.1182/blood-2025-4662

Published: 2025

Journal Articles

DDX41-related myeloid neoplasms: Insights and treatment landscape in 250 patients managed at a large tertiary centre

Francesco Versino, Shreyas Hanmantgad, Pramila Krishnamurthy, Victoria Potter, Roochi Trikha, Mili Shah, Varun Mehra, Lynn Quek, Guy Hannah, Henry Wood, Shreyans Gandhi, Joanna Large, Clair Engelbrecht, Katie Snape, Guilherme Sapinho, Steve Best, Kar Lok Kong, Austin Kulasekararaj

Blood (2025) 146 (Supplement 1): 5262.

https://doi.org/10.1182/blood-2025-5262

Published: 2025

Journal Articles

Aplastic Anemia in the Elderly: Treatment Patterns and Outcomes from an International Observational Study

Bruno Fattizzo, Carmelo Gurnari, Sabrina Giammarco, Antony Ricchiuti, Hussein Awada, Marta Bortolotti, Giacinto Luca Pedone, Francesco Versino, Dario Consonni, Roochi Trikha, Shreyans Gandhi, Simona Sica, Jaroslaw Maciejewski, Austin G. Kulasekararaj, Wilma Barcellini

Blood (2024) 144 (Supplement 1): 4076.

https://doi.org/10.1182/blood-2024-198321

Published: 2024

Journal Articles

The Association of Anemia and Patient Reported Outcomes in the New Era of PNH Treatment

Blood (2024) 144 (Supplement 1): 2321.

https://doi.org/10.1182/blood-2024-204693

Published: 2024

Journal Articles

A First Report from the COMPLETE Study on the Real-World Effectiveness of Pegcetacoplan in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH)

Régis Peffault de Latour, Roochi Trikha, Carmen Gonzalez Gonzalez, Matthias Nölte, Håkan Malmström, Stefan Lethagen

Blood (2024) 144 (Supplement 1): 5669.

https://doi.org/10.1182/blood-2024-194458

Published: 2024

Journal Articles

Treatment outcomes of complement protein C5 inhibition in 509 UK patients with paroxysmal nocturnal hemoglobinuria

Richard J. Kelly, Matthew Holt, Jennifer Vidler, Louise M. Arnold, Joanna Large, Briony Forrest, Catherine Barnfield, Alexandra Pike, Morag Griffin, Talha Munir, Petra Muus, Sateesh K. Nagumantry, Abraham Varghese, John R. Davies, Roochi Trikha, Austin G. Kulasekararaj, Lindsay Mitchell, Shreyans Gandhi

Blood (2024) 143 (12): 1157–1166.

https://doi.org/10.1182/blood.2023021762

Published: 2024

Journal Articles

Deciphering the Differential Diagnosis of Inherited Versus Acquired Bone Marrow Failure Syndromes: A Large Cohort Study

Marta Bortolotti, Roochi Trikha, Sarah Salter, Joanna Large, Shreyans Gandhi, Bruno Fattizzo, Wilma Barcellini, Austin Kulasekararaj

Blood (2023) 142 (Supplement 1): 1360.

https://doi.org/10.1182/blood-2023-186516

Published: 2023

Journal Articles

Deciphering Treatment Patterns in Non-Severe Aplastic Anemia: An International Observational Study

Bruno Fattizzo, Carmelo Gurnari, Giulio Cassanello, Marta Bortolotti, Hussein Awada, Sabrina Giammarco, Dario Consonni, Simona Sica, Shreyans Gandhi, Roochi Trikha, Jaroslaw P. Maciejewski, Austin Kulasekararaj, Wilma Barcellini

Blood (2022) 140 (Supplement 1): 8638–8640.

https://doi.org/10.1182/blood-2022-166347

Published: 2022

Journal Articles

Treatment Outcomes of Complement Protein C5 Inhibition in 509 Patients with Paroxysmal Nocturnal Hemoglobinuria in the United Kingdom

Richard Kelly, Matthew Holt, Jennifer Vidler, Louise Arnold, Joanna Large, Briony Forrest, Catherine Barnfield, Alexandra Pike, Morag Griffin, Talha Munir, Petra Muus, Sateesh K. Nagumantry, Roochi Trikha, Austin Kulasekararaj, Lindsay Mitchell, Shreyans Ghandi

Blood (2022) 140 (Supplement 1): 5792–5794.

https://doi.org/10.1182/blood-2022-167725

Published: 2022

Journal Articles

Terminal Complement Inhibition and Control of Hemolysis in Paroxysmal Nocturnal Hemoglobinuria Following Switching from High-Dose Eculizumab to Ravulizumab: An Interim Analysis

Morag Griffin, Shreyans Gandhi, Eden Hicks, Deepak Jain, Richard Kelly, Talha Munir, Petra Muus, Masayo Ogawa, Roochi Trikha, Ji Yu, Austin Kulasekararaj

Blood (2022) 140 (Supplement 1): 2928–2930.

https://doi.org/10.1182/blood-2022-159498

Published: 2022

Journal Articles

Experience of Endocrine Late Effects in Children with Haemolobinopathies Post Thiotepa Based Haematopoetic Stem Cell Transplant (HSCT) Regimens

Roochi Trikha, MB ChB, PhD, Catherine Hurley, Saji Alexander, Josu de la Fuente, Leena Karnik, MD FRCPath, MBBS,

Blood (2016) 128 (22): 5801.

https://doi.org/10.1182/blood.V128.22.5801.5801

Published: 2016

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Real-world use of oral iptacopan monotherapy in paroxysmal nocturnal hemoglobinuria

Molecular gene panel analysis in aplastic anaemia: Diagnostic utility and clinical implications

Switching between complement inhibitors in patients with PNH: A real-world analysis of strategy, efficacy, and safety.

Consistent benefits of pegcetacoplan treatment in PNH patients with and without a history of aplastic anemia in real world: Analysis of the ongoing COMPLETE Phase IV observational study

6pLOH as a marker of immune-mediated bone marrow failure: Insights from a large single center experience

Improved outcomes following allogeneic hematopoietic stem cell transplantation in patients with DDX41-mutated myeloid neoplasms: A prospective analysis of survival, GVHD, and transplant-related mortality

Paroxysmal nocturnal hemoglobinuria in pediatric patients: A UK experience

DDX41-related myeloid neoplasms: Insights and treatment landscape in 250 patients managed at a large tertiary centre

Aplastic Anemia in the Elderly: Treatment Patterns and Outcomes from an International Observational Study

The Association of Anemia and Patient Reported Outcomes in the New Era of PNH Treatment

A First Report from the COMPLETE Study on the Real-World Effectiveness of Pegcetacoplan in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH)

Treatment outcomes of complement protein C5 inhibition in 509 UK patients with paroxysmal nocturnal hemoglobinuria

Deciphering the Differential Diagnosis of Inherited Versus Acquired Bone Marrow Failure Syndromes: A Large Cohort Study

Deciphering Treatment Patterns in Non-Severe Aplastic Anemia: An International Observational Study

Treatment Outcomes of Complement Protein C5 Inhibition in 509 Patients with Paroxysmal Nocturnal Hemoglobinuria in the United Kingdom

Terminal Complement Inhibition and Control of Hemolysis in Paroxysmal Nocturnal Hemoglobinuria Following Switching from High-Dose Eculizumab to Ravulizumab: An Interim Analysis

Experience of Endocrine Late Effects in Children with Haemolobinopathies Post Thiotepa Based Haematopoetic Stem Cell Transplant (HSCT) Regimens

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