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Alexandra Pike
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Journal Articles

The effect of breakthrough hemolysis on complement factor h and factor I levels in paroxysmal nocturnal hemoglobinuria

Free
Matthew Holt, Daniel Payne, Natalie Fox, Claire McKinley, Morag Griffin, Petra Muus, Talha Munir, Alexandra Pike, Louise Arnold, Sateesh Nagumantry, Richard Kelly, Darren Newton
Journal: Blood
Blood (2025) 146 (Supplement 1): 3193.
https://doi.org/10.1182/blood-2025-3193
Published: 2025
Journal Articles

Spontaneous remissions in paroxysmal nocturnal hemoglobinuria: True remission or clonal evolution to malignancy?

Free
Caitlin Roger, Matthew Holt, Louise Arnold, Lindsay Mitchell, Sateesh Nagumantry, Katharine Lowndes, Alexandra Pike, Talha Munir, Petra Muus, Morag Griffin, Richard Kelly
Journal: Blood
Blood (2025) 146 (Supplement 1): 29.
https://doi.org/10.1182/blood-2025-29
Published: 2025
Journal Articles

Real-world use of oral iptacopan monotherapy in paroxysmal nocturnal hemoglobinuria

Free
Matthew Holt, Richard Kelly, Regis Peffault De Latour, Morag Griffin, Shreyans Gandhi, Edouard Forcade, Francesco Versino, Roochi Trikha, Alexandra Pike, Joanna Large, Michael Loschi, Marc Michel, Petra Muus, Talha Munir, Alice Garnier, Simona Pagliuca, Yosr Hicheri, Isabelle Brindel, Sateesh Nagumantry, Lynda Maafa, Louise Arnold, Austin Kulasekararaj, Flore Sicre-de-Fontbrune
Journal: Blood
Blood (2025) 146 (Supplement 1): 1427.
https://doi.org/10.1182/blood-2025-1427
Published: 2025
Journal Articles

Switching between complement inhibitors in patients with PNH: A real-world analysis of strategy, efficacy, and safety.

Free
Morag Griffin, Bruno Fattizzo, Jong Wook Lee, Richard Kelly, Roochi Trikha, Yasutaka Ueda, Jun-ichi Nishimura, Christopher Patriquin, Alexander Röth, Petra Muus, Jens Panse, Miguel Gómez Álvarez, Alexandra Pike, Talha Munir, Shreyans Gandhi, Austin Kulasekararaj
Journal: Blood
Blood (2025) 146 (Supplement 1): 1114.
https://doi.org/10.1182/blood-2025-1114
Published: 2025
Journal Articles

The use of anticoagulation on paroxysmal nocturnal hemoglobinuria.

Free
Louise Arnold, Petra Muus, Talha Munir, Alexandra Pike, Sateesh Nagumantry, Hussnain Javaid, Matthew Holt, Elizabeth Littlewood, Amy Todd, Emily Groom-White, Morag Griffin, Richard Kelly
Journal: Blood
Blood (2025) 146 (Supplement 1): 1111.
https://doi.org/10.1182/blood-2025-1111
Published: 2025
Journal Articles

Factor bb as a biomarker during breakthrough hemolysis in paroxysmal nocturnal hemoglobinuria

Free
Matthew Holt, Daniel Payne, Natalie Fox, Claire McKinley, Morag Griffin, Petra Muus, Talha Munir, Alexandra Pike, Louise Arnold, Sateesh Nagumantry, Darren Newton, Richard Kelly
Journal: Blood
Blood (2025) 146 (Supplement 1): 4973.
https://doi.org/10.1182/blood-2025-4973
Published: 2025
Journal Articles

Paroxysmal nocturnal hemoglobinuria in pediatric patients: A UK experience

Free
Morag Griffin, Malinthi Adikarama, Shreyans Gandhi, Petra Muus, Alexandra Pike, Talha Munir, Matthew Holt, Louise Arnold, Franceso Versino, Joanna Large, Richard Kelly, Austin Kulasekararaj, Roochi Trikha
Journal: Blood
Blood (2025) 146 (Supplement 1): 4662.
https://doi.org/10.1182/blood-2025-4662
Published: 2025
Journal Articles

Treatment outcomes of complement protein C5 inhibition in 509 UK patients with paroxysmal nocturnal hemoglobinuria

Free
CME Clinical Trials & Observations
Richard J. Kelly, Matthew Holt, Jennifer Vidler, Louise M. Arnold, Joanna Large, Briony Forrest, Catherine Barnfield, Alexandra Pike, Morag Griffin, Talha Munir, Petra Muus, Sateesh K. Nagumantry, Abraham Varghese, John R. Davies, Roochi Trikha, Austin G. Kulasekararaj, Lindsay Mitchell, Shreyans Gandhi
Journal: Blood
Blood (2024) 143 (12): 1157–1166.
https://doi.org/10.1182/blood.2023021762
Published: 2024
Journal Articles

Sars-Cov-2 Antibody and T-Cell Responses in Patients with Paroxysmal Nocturnal Hemoglobinuria and Aplastic Anemia after Four COVID-19 Vaccinations

Free
Alexandra Pike, Natalie Fox, Claire E McKinley, Louise M Arnold, Mark Harland, Deborah Clarke, Briony Forrest, Nicola Houghton, Nora Youngs, Emily Charlton, Tapiwa Zhakata, Catherine Barnfield, Ruth Harvey, Mary Wu, Caitlin Kavanagh, Stephen John Richards, Daniel Payne, Abraham Mullasseril Varghese, Sateesh Nagumantry, Talha Munir, Petra Muus, Morag Griffin, Darren Newton, Peter Hillmen, Richard J Kelly
Journal: Blood
Blood (2023) 142 (Supplement 1): 2712.
https://doi.org/10.1182/blood-2023-190393
Published: 2023
Journal Articles

Paroxysmal Nocturnal Haemoglobinuria (PNH) Arising from Non-Canonical Mutations

Free
Alexandra Pike, Stephen John Richards, Claire E McKinley, Louise M Arnold, Abraham Mullasseril Varghese, Talha Munir, Petra Muus, Peter Hillmen, Morag Griffin, Richard J Kelly, Darren Newton
Journal: Blood
Blood (2023) 142 (Supplement 1): 4097.
https://doi.org/10.1182/blood-2023-188755
Published: 2023
Journal Articles

Experience of compassionate-use pegcetacoplan for paroxysmal nocturnal hemoglobinuria

Free
Clinical Trials & Observations
Morag Griffin, Petra Muus, Talha Munir, Sateesh Nagumantry, Alexandra Pike, Louise Arnold, Briony Forrest, Catherine Barnfield, Nicola Houghton, Nora Youngs, Richard Kelly
Journal: Blood
Blood (2023) 141 (1): 116–120.
https://doi.org/10.1182/blood.2022017266
Published: 2023
Journal Articles

Treatment Outcomes of Complement Protein C5 Inhibition in 509 Patients with Paroxysmal Nocturnal Hemoglobinuria in the United Kingdom

Free
Richard Kelly, Matthew Holt, Jennifer Vidler, Louise Arnold, Joanna Large, Briony Forrest, Catherine Barnfield, Alexandra Pike, Morag Griffin, Talha Munir, Petra Muus, Sateesh K. Nagumantry, Roochi Trikha, Austin Kulasekararaj, Lindsay Mitchell, Shreyans Ghandi
Journal: Blood
Blood (2022) 140 (Supplement 1): 5792–5794.
https://doi.org/10.1182/blood-2022-167725
Published: 2022
Journal Articles

Incomplete Complement Inhibition in Patients with PNH on Eculizumab - 5 Year Experience from the National PNH Service Leeds

Free
Rachael Jones, BSc, Petra Muus, MD PhD, Talha Munir, MBBS, Alexandra Pike, MBBS, Louise Arnold, Jeanifer Gachev, Briony Forrest, Peter Hillmen, MBChB, PhD, Morag Griffin, MBChB, FRCPath
Journal: Blood
Blood (2020) 136 (Supplement 1): 8–9.
https://doi.org/10.1182/blood-2020-140256
Published: 2020
Journal Articles

Management of Meningococcal Disease Risk in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) on Complement Inhibitors: 18 Years' Experience from the UK National PNH Service in Leeds

Free
Louise Arnold, Ray Borrow, PhD FRCPath, Kathryn Riley, Talha Munir, MBBS, Richard Kelly, BSc, MD, Rachael Jones, BSc, Jeanifer Gachev, Briony Forrest, Alexandra Pike, MBBS, Petra Muus, MD PhD, Peter Hillmen, MBChB, PhD, Morag Griffin, MBChB, FRCPath
Journal: Blood
Blood (2020) 136 (Supplement 1): 5–6.
https://doi.org/10.1182/blood-2020-141780
Published: 2020
Journal Articles

Thrombotic Events with Neisseria Meningitidis Vaccination in Patients with Paroxysmal Nocturnal Hemoglobinuria, UK Experience

Free
Louise Arnold, Richard Kelly, BSc, MD, Talha Munir, MBBS, Petra Muus, MD PhD, Alexandra Pike, MBBS, Kathryn Riley, Briony Forrest, Jeanifer Gachev, Morag Griffin, MBChB, FRCPath, Peter Hillmen, MBChB, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 35–36.
https://doi.org/10.1182/blood-2020-141769
Published: 2020