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Journal Articles

Potency and Efficacy of Pharmacological PIP4K2 Inhibitors in Acute Lymphoblastic Leukemia

Keli Lima, Maria Fernanda Lopes Carvalho, Diego A. Pereira-Martins, Wellington F Silva, Mariane Cristina do Nascimento, Lívia Bassani Lins de Miranda, Rita de Cássia Cavaglieri Medeiros, Luciana Nardinelli, Aline de Medeiros Leal, Elvira Deolinda Rodrigues Pereira Velloso, Israel Bendit, Jan Jacob Schuringa, João Agostinho Machado-Neto, Eduardo Magalhães Rego
Journal: Blood
Blood (2023) 142 (Supplement 1): 5786.
https://doi.org/10.1182/blood-2023-189786
Published: 2023
Journal Articles

Identification of Vulnerabilities for Pharmacological Inhibition of PIP4K2s in Acute Myeloid Leukemia

Keli Lima, Maria Fernanda Lopes Carvalho, Diego A Pereira-Martins, Lívia Bassani Lins de Miranda, Mariane Cristina do Nascimento, Frederico Lisboa Nogueira, Rita de Cássia Cavaglieri Medeiros, Jan Jacob Schuringa, João Agostinho Machado-Neto, Eduardo Magalhães Rego
Journal: Blood
Blood (2023) 142 (Supplement 1): 5774.
https://doi.org/10.1182/blood-2023-189998
Published: 2023
Journal Articles

Feasibility and Relevance of Incorporating Genetic Testing By Next-Generation Sequencing for Acute Myeloid Leukemia Patients Treated in Low- and Middle-Income Countries

Fabiola Traina, Lorena Lobo Figueiredo-Pontes, Maria Isabel Ayrosa, Katia B Pagnano, Ana Beatriz F Gloria, Elvira Deolinda Rodrigues Pereira Velloso, Elenaide C. Nunes, Marcia Higashi, Bruno Kosa Lino Duarte, Evandro M Fagundes, Wellington F Silva, Brunno Gilberto Santos Macedo, Rita de Cássia Cavaglieri Medeiros, Ana Sílvia Gouvêa Lima Yamada, Patricia C Ruy, Melissa Rijken, Bob Lowenberg, Torsten Haferlach, Arnold Ganser, Richard Dillon, Nancy Berliner, Peter J. M. Valk, Eduardo Magalhães Rego
Journal: Blood
Blood (2023) 142 (Supplement 1): 2929.
https://doi.org/10.1182/blood-2023-189806
Published: 2023
Journal Articles

Real-World Data for FLT3-Mutated Acute Myeloid Leukemia Patients Treated in Resource-Constrained Settings

Wellington F Silva, Fernanda Rodrigues Mendes, Marco Sartori, Maria Isabel A Madeira, Katia B Pagnano, Ana Beatriz F Gloria, Elenaide C. Nunes, Luciana Nardinelli, Rita De Cássia Cavaglieri Medeiros, Israel Bendit, Fabiola Traina, Bruno Kosa Lino Duarte, Lorena Lobo Figueiredo-Pontes, Vanderson Rocha, Elvira Deolinda Rodrigues Pereira Velloso, Eduardo Magalhães Rego
Journal: Blood
Blood (2023) 142 (Supplement 1): 5839.
https://doi.org/10.1182/blood-2023-187902
Published: 2023
Journal Articles

Targeting PIP4K2 Lipid Kinases through Thz-P1-2 Reveals Vulnerabilities Related to Mitochondrial Homeostasis and Autophagy in Acute Leukemia

Keli Lima, Diego A Pereira-Martins, Lívia Bassani Lins de Miranda, Juan L Coelho-Silva, Giovana da Silva Leandro, Isabel Weinhäuser, Rita de Cassia Cavaglieri, Wellington F Silva, Aline Medeiros Leal, Ana Paula Alencar de Lima Lange, Elvira Deolinda Rodrigues Pereira Velloso, Emmanuel Griessinger, Jacobien R Hilberink, Gerwin A. Huls, Jan Jacob Schuringa, João Agostinho Machado-Neto, Eduardo M Rego
Journal: Blood
Blood (2022) 140 (Supplement 1): 5965–5966.
https://doi.org/10.1182/blood-2022-165172
Published: 2022
Journal Articles

Treatment with the Recombinant SLIT2 Protein Delays AML Leukemogenesis In Vivo

Luise A de Albuquerque Simoes, Isabel Weinhäuser, Diego A Pereira-Martins, César Alexander Ortiz Rojas, Thiago Mantello Bianco, Rita de Cassia Cavaglieri, Eduardo M Rego
Journal: Blood
Blood (2021) 138 (Supplement 1): 2368.
https://doi.org/10.1182/blood-2021-151069
Published: 2021