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Thiago Mantello Bianco
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Journal Articles

The Oncogenic ΔNp73α Isoform Contributes to Aggressiveness in APL By Leading to ATRA Resistance through NANOG/BMP4 Axis Upregulation

César Alexander Ortiz Rojas, Diego A. Pereira-Martins, Carol Thomé, Germano Ferreira, Thiago Mantello Bianco, Isabel Weinhäuser, Cleide Lúcia Araújo Silva, Lorena Pontes, Vitor Faça, Emanuele Ammatuna, Gerwin Huls, Jan Jacob Schuringa, Eduardo M. Rego
Journal: Blood
Blood (2024) 144 (Supplement 1): 1350.
https://doi.org/10.1182/blood-2024-205613
Published: 2024
Journal Articles

The Oncogenic Function of the Intrinsically Disordered Transcriptional Regulator MN1 Depends on the Chaperone DNAJB6b

Diego A. Pereira-Martins, Vincent Van Den Boom, Isabel Weinhaeuser, Nisha van der Meer, Prodromos Chatzikyriakou, Noortje van Dijk, Xuesen Zheng, Lucio H Pinheiro, Douglas RA Silveira, Thiago Mantello Bianco, César Alexander Ortiz Rojas, Eduardo M. Rego, Stuart A Rushworth, Antonio R. Lucena-Araujo, Lynn Quek, Gerwin Huls, Jan Jacob Schuringa
Journal: Blood
Blood (2024) 144 (Supplement 1): 4321.
https://doi.org/10.1182/blood-2024-207421
Published: 2024
Journal Articles

CEBPA-Driven Expression of the Transcriptionally Inactive deltaTP73 Isoform Phenocopies TP53 mutated Poor Risk and Drug-Resistant Acute Myeloid Leukemia

Diego Pereira-Martins, César Alexander Ortiz Rojas, Isabel Weinhaeuser, Bart-Jan Wierenga, Vincent Van Den Boom, Fatemeh Mojallali, Dominique Sternadt, Thiago Mantello Bianco, Nisha van der Meer, Douglas RA Silveira, Lynn Quek, Emanuele Ammatuna, Antonio R Lucena-Araujo, Gerwin A. Huls, Eduardo Magalhães Rego, Jan Jacob Schuringa
Journal: Blood
Blood (2023) 142 (Supplement 1): 839.
https://doi.org/10.1182/blood-2023-186399
Published: 2023
Journal Articles

Treatment with the Recombinant SLIT2 Protein Delays AML Leukemogenesis In Vivo

Luise A de Albuquerque Simoes, Isabel Weinhäuser, Diego A Pereira-Martins, César Alexander Ortiz Rojas, Thiago Mantello Bianco, Rita de Cassia Cavaglieri, Eduardo M Rego
Journal: Blood
Blood (2021) 138 (Supplement 1): 2368.
https://doi.org/10.1182/blood-2021-151069
Published: 2021
Journal Articles

Clinical and Functional Studies Reveal That TP73 Isoforms Levels Are Associated with Prognosis and RA-Resistance in Acute Promyelocytic Leukemia

César Alexander Ortiz Rojas, BSc, Diego A Pereira-Martins, MSc, Isabel Weinhäuser, MSc, Luciana Yamamoto Almeida, PhD, Thiago Mantello Bianco, MSc, Lorena Lobo Figueiredo-Pontes, MD PhD, Luisa C A Koury, MD, Raul Antônio Morais Melo, MD PhD, Rosane Bittencourt, Katia B Pagnano, MD PhD, Ricardo Pasquini, MD, Elenaide C. Nunes, MD, Evandro Maranhão Fagundes, MD, Ana Beatriz F. Gloria, MD, Fabio R. Kerbauy, MD, Armand Keating, MD, Martin S. Tallman, MD, Raul Ribeiro, MD, Richard Dillon, MA, PhD MRCP, FRCPath, Arnold Ganser, MD, Bob Löwenberg, MD PhD, Peter Valk, PhD, Miguel A. Sanz, Nancy Berliner, MD, Eduardo M Rego, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2719.
https://doi.org/10.1182/blood-2019-131211
Published: 2019
Journal Articles

Efficacy of the Pan-Bcl-2 Inhibitor (Obatoclax) As a Single Agent to Treat Myeloproliferative Neoplasm in JAK2V617F Murine Transplantation Model

Thiago Mantello Bianco, MSc, Juan L Coelho-Silva, BSc, MSc, Diego A Pereira-Martins, MSc, Priscila Santos Scheucher, PhD, Isabel Weinhäuser, MSc, Antonio Bruno Alves Silva, BSc, Cleide Lucia Silva, MSc, Ann Mullally, MD, Susumu S Kobayashi, MD PhD, Eduardo M Rego, MD PhD, Fabiola Traina, MD PhD, Lorena Lobo Figueiredo-Pontes, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2977.
https://doi.org/10.1182/blood-2019-131023
Published: 2019
Journal Articles

Metformin Suppress Cellular and Molecular Processes Related to Maintenance and Proliferation of Myeloproliferative Neoplasm Stem Cell

Juan L Coelho-Silva, BSc, MSc, Thiago Mantello Bianco, MSc, Antonio Bruno Alves Silva, BSc, Diego Antonio Pereira-Martins, M.Sc., Natasha Peixoto Fonseca, B.Sc., M.Sc., Isabel Weinhäuser, MSc, Eduardo M Rego, MD PhD, Fernando Chahud, MD PhD, João Agostinho Machado-Neto, PhD, Lorena Lobo Figueiredo-Pontes, MD PhD, Fabiola Traina, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1682.
https://doi.org/10.1182/blood-2019-132115
Published: 2019
Journal Articles

Reduced SLIT2 Are Associated with Increased Cell Proliferation and Arsenic Trioxide Resistance in APL Cells

Isabel Weinhäuser, MSc, Diego A Pereira-Martins, MSc, Luíse A A Simões, BSc, César Alexander Ortiz Rojas, BSc, Thiago Mantello Bianco, MSc, Cleide Lucia Silva, MSc, Mariane Cristina Do Nascimento, BSc, Lorena Lobo Figueiredo-Pontes, MD PhD, Antonio R. Lucena-Araujo, PhD, Eduardo M Rego, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5165.
https://doi.org/10.1182/blood-2019-131496
Published: 2019
Journal Articles

Abnormal Distribution and Function of NK Cells Subsets May Lead to Impaired Tumor Surveillance in a JAK2V617F Myeloproliferative Neoplasm Model

Thiago Mantello Bianco, MSc, Diego Antonio Pereira-Martins, MSc, Patrícia Vianna Bonini Palma, BSc, Josiane Lilian Schiavinato, PhD, Cleide Araújo Silva, MSc, Ann Mullally, MD, Susumu S Kobayashi, MD PhD, Eduardo Magalhães Rego, MD PhD, Lorena Lobo Figueiredo-Pontes, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4335.
https://doi.org/10.1182/blood-2018-99-115006
Published: 2018
Journal Articles

C/Ebpg (CCAAT/Enhancer Binding Protein Gamma) Balances Cytotoxic and Secretory Potential of Natural Killer Cells

Izabela Aparecida Lopes, MSc, Miroslava Kardosova, MSc, Thiago Mantello Bianco, MSc, Adriana Queiroz Arantes, MD, Cleide Araújo Silva, MSc, Priscila Santos Scheucher, PhD, Daniel G. Tenen, MD, Sanghoon Lee, PhD, Eduardo Magalhães Rego, MD PhD, Robert S. Welner, PhD, Meritxell Alberich-Jorda, Lorena Lobo Figueiredo-Pontes, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3721.
https://doi.org/10.1182/blood-2018-99-119389
Published: 2018
Journal Articles

Imbalance between Tolerant and Cytotoxic Functional Subsets of NK Cells in a JAK2 V617F Myeloproliferative Neoplasm Model

Thiago Mantello Bianco, MSc, Adriana Queiroz Arantes, MD, Izabela Aparecida Lopes, MSc, Priscila Santos Scheucher, PhD, Cleide Araújo Silva, MSc, Ann Mullally, MD, Susumu S Kobayashi, MD PhD, Eduardo Magalhães Rego, MDPhD, Lorena Lobo Figueiredo-Pontes, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4221.
https://doi.org/10.1182/blood.V130.Suppl_1.4221.4221
Published: 2017