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Journal Articles

A novel humanized mouse model with significant improvement of class-switched, antigen-specific antibody production

Hua Yu, Chiara Borsotti, Jean-Nicolas Schickel, Shu Zhu, Till Strowig, Elizabeth E. Eynon, Davor Frleta, Cagan Gurer, Andrew J. Murphy, George D. Yancopoulos, Eric Meffre, Markus G. Manz, Richard A. Flavell

Blood (2017) 129 (8): 959–969.

https://doi.org/10.1182/blood-2016-04-709584

Published: 2017

Includes: Supplemental data

Journal Articles

inv(16) and NPM1 mut AMLs engraft human cytokine knock-in mice

Jana M. Ellegast, Philipp J. Rauch, Larisa V. Kovtonyuk, Rouven Müller, Ulrich Wagner, Yasuyuki Saito, Nicole Wildner-Verhey van Wijk, Christine Fritz, Anahita Rafiei, Veronika Lysenko, Ewa Dudkiewicz, Alexandre P. Theocharides, Davide Soldini, Jeroen S. Goede, Richard A. Flavell, Markus G. Manz

Blood (2016) 128 (17): 2130–2134.

https://doi.org/10.1182/blood-2015-12-689356

Published: 2016

Includes: Supplemental data

Journal Articles

Peripheral blood CD34 + cells efficiently engraft human cytokine knock-in mice

Yasuyuki Saito, Jana M. Ellegast, Anahita Rafiei, Yuanbin Song, Daniel Kull, Mathias Heikenwalder, Anthony Rongvaux, Stephanie Halene, Richard A. Flavell, Markus G. Manz

Blood (2016) 128 (14): 1829–1833.

https://doi.org/10.1182/blood-2015-10-676452

Published: 2016

Includes: Supplemental data

Journal Articles

Adult Donor-Derived Human CD34 + Cell Engraftment and Hemato-Lymphoid System Development in 3rd Generation Humanized Mice

Yasuyuki Saito, MD PhD, Jana M. Ellegast, MD, Rouven Müller, MD, Richard A. Flavell, PhD, Markus G. Manz, MD

Blood (2014) 124 (21): 4378.

https://doi.org/10.1182/blood.V124.21.4378.4378

Published: 2014

Journal Articles

Next Generation Humanized Mice Support Engraftment of Myelofibrosis CD34+ Cells

Alexandre P.A. Theocharides, MD, Rouven Müller, MD, Yasuyuki Saito, MD PhD, Richard A. Flavell, PhD, Markus G. Manz, MD

Blood (2014) 124 (21): 1880.

https://doi.org/10.1182/blood.V124.21.1880.1880

Published: 2014

Journal Articles

ΜΙSΤRG Mice Support Good-Risk AML Engraftment

Jana M. Ellegast, MD, Yasuyuki Saito, MD PhD, Richard A. Flavell, PhD, Markus G. Manz, MD

Blood (2014) 124 (21): 3808.

https://doi.org/10.1182/blood.V124.21.3808.3808

Published: 2014

Journal Articles

Engraftment Of Human Polycythemia Vera CD34+ Cells In hSIRPα-Transgenic-Human-TPO-Expressing RAG2 -/- , IL2Rγ -/- Immunodeficient Mice

Rouven Müller, MD, Alexandre Theocharides, MD, Renate Looser, Radek C. Skoda, M.D., Richard A. Flavell, PhD, Markus G. Manz, MD

Blood (2013) 122 (21): 2844.

https://doi.org/10.1182/blood.V122.21.2844.2844

Published: 2013

Journal Articles

Development of a Novel in Vivo Model for Human Myeloma Via Humanization of the Bone Marrow Niche

Till Strowig, Anja Hafemann, Stephanie Hopf, Kartik Sehgal, Srinivas Koduru, Mehmet H. Kocoglu, MD, Rituparna Das, Madhav V. Dhodapkar, MD, Richard A. Flavell, PhD

Blood (2012) 120 (21): 325.

https://doi.org/10.1182/blood.V120.21.325.325

Published: 2012

Journal Articles

Dendritic cell–mediated activation-induced cytidine deaminase (AID)–dependent induction of genomic instability in human myeloma

Srinivas Koduru, Ellice Wong, Till Strowig, Ranjini Sundaram, Lin Zhang, Matthew P. Strout, Richard A. Flavell, David G. Schatz, Kavita M. Dhodapkar, Madhav V. Dhodapkar

Blood (2012) 119 (10): 2302–2309.

https://doi.org/10.1182/blood-2011-08-376236

Published: 2012

Journal Articles

Efficient differentiation and function of human macrophages in humanized CSF-1 mice

Chozhavendan Rathinam, William T. Poueymirou, Jose Rojas, Andrew J. Murphy, David M. Valenzuela, George D. Yancopoulos, Anthony Rongvaux, Elizabeth E. Eynon, Markus G. Manz, Richard A. Flavell

Blood (2011) 118 (11): 3119–3128.

https://doi.org/10.1182/blood-2010-12-326926

Published: 2011

Includes: Supplemental data

Journal Articles

Human Interleukin-3/Granulocyte Macrophage-Colony Stimulating Factor Knock-In Mice Support Human Myeloid Cell Reconstitution and Human Immune Responses In the Lung.

Tim Willinger, MD, PhD, Anthony Rongvaux, PhD, Hitoshi Takizawa, PhD, Elizabeth E. Eynon, PhD, Sean Stevens, PhD, Markus G Manz, MD, Richard A. Flavell, PhD

Blood (2010) 116 (21): 3789.

https://doi.org/10.1182/blood.V116.21.3789.3789

Published: 2010

Journal Articles

Human Thrombopoietin Knockin Mice Efficiently Support Human Hematopoiesis In Vivo

Anthony Rongvaux, Tim Willinger, Hitoshi Takizawa, PhD, Chozhavendan Rathinam, Elizabeth E. Eynon, PhD, Sean Stevens, PhD, Markus G Manz, MD, Richard A. Flavell, PhD

Blood (2010) 116 (21): 403.

https://doi.org/10.1182/blood.V116.21.403.403

Published: 2010

Journal Articles

Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis

Dirk Lievens, Alma Zernecke, Tom Seijkens, Oliver Soehnlein, Linda Beckers, Imke C. A. Munnix, Erwin Wijnands, Pieter Goossens, Roger van Kruchten, Larissa Thevissen, Louis Boon, Richard A. Flavell, Randolph J. Noelle, Norbert Gerdes, Erik A. Biessen, Mat J. A. P. Daemen, Johan W. M. Heemskerk, Christian Weber, Esther Lutgens

Blood (2010) 116 (20): 4317–4327.

https://doi.org/10.1182/blood-2010-01-261206

Published: 2010

Includes: Supplemental data

Journal Articles

Regulating human Th17 cells via differential expression of IL-1 receptor

Won-Woo Lee, Seong Wook Kang, Jihoon Choi, Seung-Hyun Lee, Kamini Shah, Elizabeth E. Eynon, Richard A. Flavell, Insoo Kang

Blood (2010) 115 (3): 530–540.

https://doi.org/10.1182/blood-2009-08-236521

Published: 2010

Includes: Supplemental data

Journal Articles

The hematopoiesis paradigm: clarity or ambiguity?

Chozhavendan Rathinam, Richard A. Flavell

Blood (2008) 112 (9): 3534–3535.

https://doi.org/10.1182/blood-2008-07-167759

Published: 2008

Journal Articles

Alpha-4 integrins and VCAM-1, but not MAdCAM-1, are essential for recruitment of mast cell progenitors to the inflamed lung

J. Pablo Abonia, Jenny Hallgren, Tatiana Jones, Tong Shi, Yuhui Xu, Pandelakis Koni, Richard A. Flavell, Joshua A. Boyce, K. Frank Austen, Michael F. Gurish

Blood (2006) 108 (5): 1588–1594.

https://doi.org/10.1182/blood-2005-12-012781

Published: 2006

Journal Articles

Constitutive homing of mast cell progenitors to the intestine depends on autologous expression of the chemokine receptor CXCR2

J. Pablo Abonia, K. Frank Austen, Barrett J. Rollins, Sunil K. Joshi, Richard A. Flavell, William A. Kuziel, Pandelakis A. Koni, Michael F. Gurish

Blood (2005) 105 (11): 4308–4313.

https://doi.org/10.1182/blood-2004-09-3578

Published: 2005

Journal Articles

Overexpression of IL-7Rα provides a competitive advantage during early T-cell development

Yasmina Laouar, I. Nicholas Crispe, Richard A. Flavell

Blood (2004) 103 (6): 1985–1994.

https://doi.org/10.1182/blood-2003-06-2126

Published: 2004

Journal Articles

Integrated src kinase and costimulatory activity enhances signal transduction through single-chain chimeric receptors in T lymphocytes

Terrence L. Geiger, Phuong Nguyen, David Leitenberg, Richard A. Flavell

Blood (2001) 98 (8): 2364–2371.

https://doi.org/10.1182/blood.V98.8.2364

Published: 2001

NARROW

A novel humanized mouse model with significant improvement of class-switched, antigen-specific antibody production

inv(16) and NPM1 mut AMLs engraft human cytokine knock-in mice

Peripheral blood CD34 + cells efficiently engraft human cytokine knock-in mice

Adult Donor-Derived Human CD34 + Cell Engraftment and Hemato-Lymphoid System Development in 3rd Generation Humanized Mice

Next Generation Humanized Mice Support Engraftment of Myelofibrosis CD34+ Cells

ΜΙSΤRG Mice Support Good-Risk AML Engraftment

Engraftment Of Human Polycythemia Vera CD34+ Cells In hSIRPα-Transgenic-Human-TPO-Expressing RAG2 -/- , IL2Rγ -/- Immunodeficient Mice

Development of a Novel in Vivo Model for Human Myeloma Via Humanization of the Bone Marrow Niche

Dendritic cell–mediated activation-induced cytidine deaminase (AID)–dependent induction of genomic instability in human myeloma

Efficient differentiation and function of human macrophages in humanized CSF-1 mice

Human Interleukin-3/Granulocyte Macrophage-Colony Stimulating Factor Knock-In Mice Support Human Myeloid Cell Reconstitution and Human Immune Responses In the Lung.

Human Thrombopoietin Knockin Mice Efficiently Support Human Hematopoiesis In Vivo

Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis

Regulating human Th17 cells via differential expression of IL-1 receptor

The hematopoiesis paradigm: clarity or ambiguity?

Alpha-4 integrins and VCAM-1, but not MAdCAM-1, are essential for recruitment of mast cell progenitors to the inflamed lung

Constitutive homing of mast cell progenitors to the intestine depends on autologous expression of the chemokine receptor CXCR2

Overexpression of IL-7Rα provides a competitive advantage during early T-cell development

Integrated src kinase and costimulatory activity enhances signal transduction through single-chain chimeric receptors in T lymphocytes

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American Society of Hematology

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ASH Publications

American Society of Hematology

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