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María Ortiz-Estévez
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Journal Articles

Single-Cell Atlas of Diffuse Large B-Cell Lymphoma Reveals Integrated Malignant B Cell and Tumor Microenvironment Characteristics Associated with Clinical Response

Sabrina Baaklini, Alexandre Sarrabay, Adrien Mazuel, Bertrand Escaliere, Chuang Dong, Camille Barthelemy, Laurine Gil, Laila Dahbi, Noushin Mossadegh-Keller, Nathalie Van Acker, Pauline Gravelle, Jean-Marc Navarro, Caroline Huber, Romain Fenouil, Romane Trombetta, Marine Pujol, Philippe Gaulard, Benjamin Riviere, Peggy Dartigues, Francesco Llamas Gutierrez, Celine Pangault, Fabrice Jardin, François Lemonnier, Gilles Salles, Corinne Haioun, Gabriel Brisou, Matthew E. Stokes, Sahil Seth, Maria Ortiz Estevez, Camille Laurent, Lionel Spinelli, Mark Kaplan, C. Chris Huang, Anita K. Gandhi, Bertrand Nadel, Sandrine Roulland, Pierre Milpied
Journal: Blood
Blood (2024) 144 (Supplement 1): 1597.
https://doi.org/10.1182/blood-2024-209815
Published: 2024
Journal Articles

DNMT3A-Mutant Clonal Haematopoiesis Is Associated with Worse Recovery after ST-Elevation Myocardial Infarction Via Increased Inflammation

Sarah J Mackie, Matthew Sadler, Maroof Hasan, Lynette Graver, Rupavidhya Mondi Anandhakrishna, Fulye Argunhan, Louis-Francois Handfield, Hosanna Assefa-Kebede, Laarni Bogaanay, Prodromos Chatzikyriakou, Pilar Casares Alaez, Antonio Cannata, Mohammad Al-Agil, Amandine Tan, Maria Ortiz Estevez, Ching-Pin Chang, Rajasekhar N.V.S. Suragani, Anita K. Gandhi, Ajay Shah, Theresa McDonagh, Aleksander Ivetic, Ghulam Mufti, Giorgio Napolitani, Daniel Bromage, Lynn Quek
Journal: Blood
Blood (2024) 144 (Supplement 1): 1284.
https://doi.org/10.1182/blood-2024-203813
Published: 2024
Journal Articles

Golcadomide-Mediated Degradation of Aiolos/Ikaros Synergizes with BET Inhibitors through Bidirectional Restructuring of the Directly Regulated Epigenetic Environment in DLBCL

Chih-Chao Hsu, Junfei Zhao, Ann Polonskaia, Chad C. Bjorklund, Maria Ortiz Estevez, Anita K. Gandhi, Patrick R. Hagner
Journal: Blood
Blood (2024) 144 (Supplement 1): 2739.
https://doi.org/10.1182/blood-2024-200270
Published: 2024
Journal Articles

A Single Cell Atlas of Follicular Lymphoma across Clinical Stages Defines Tumor B Cell Archetypes, Immune Microenvironment Heterogeneity and Novel Cell States Associated with High-Risk FL

Alexandre Sarrabay, Sabrina Baaklini, Camille Barthelemy, Laurine Gil, Alicia Beyou, Laila Dahbi, Noushin Mossadegh-Keller, Caroline Huber, Jean-Marc Navarro, Gilles Salles, Gabriel Brisou, Maria Ortiz Estevez, Matthew E. Stokes, Sahil Seth, C. Chris Huang, Mark Kaplan, Lionel Spinelli, Anita K. Gandhi, Bertrand Nadel, Pierre Milpied, Sandrine Roulland
Journal: Blood
Blood (2024) 144 (Supplement 1): 740.
https://doi.org/10.1182/blood-2024-209642
Published: 2024
Journal Articles

Mezigdomide Reverses T-Cell Exhaustion through Degradation of Aiolos/Ikaros and Reinvigoration of Cytokine Production Pathways

Hsiling Chiu, Junfei Zhao, Maria Ortiz Estevez, Patrick R Hagner, Anita K. Gandhi
Journal: Blood
Blood (2023) 142 (Supplement 1): 335.
https://doi.org/10.1182/blood-2023-189445
Published: 2023
Journal Articles

The location of the t(4;14) translocation breakpoint within the NSD2 gene identifies a subset of patients with high-risk NDMM

Clinical Trials & Observations
Nicholas Stong, María Ortiz-Estévez, Fadi Towfic, Mehmet Samur, Amit Agarwal, Jill Corre, Erin Flynt, Nikhil Munshi, Hervé Avet-Loiseau, Anjan Thakurta
Journal: Blood
Blood (2023) 141 (13): 1574–1583.
https://doi.org/10.1182/blood.2022016212
Published: 2023
Includes: Supplemental data
Journal Articles

Whole-genome analysis identifies novel drivers and high-risk double-hit events in relapsed/refractory myeloma

Naser Ansari-Pour, Mehmet Samur, Erin Flynt, Sarah Gooding, Fadi Towfic, Nicholas Stong, Maria Ortiz Estevez, Konstantinos Mavrommatis, Brian Walker, Gareth Morgan, Nikhil Munshi, Herve Avet-Loiseau, Anjan Thakurta
Journal: Blood
Blood (2023) 141 (6): 620–633.
https://doi.org/10.1182/blood.2022017010
Published: 2023
Includes: Supplemental data
Journal Articles

Biological Features of a High-Risk Transcriptional Molecular Subtype in Diffuse Large B-Cell Lymphoma

Matthew E Stokes, Kerstin Wenzl, C. Chris Huang, Maria Ortiz Estevez, Matthew J. Maurer, Nicholas Stong, Patrick Hagner, Yumi Nakayama, Chih-Chao Hsu, Samuel A Danziger, Fadi Towfic, Rebecca L. King, Joel S. Parker, Brian K. Link, Susan L. Slager, Vivekananda Sarangi, Yan Asmann, Joseph P. Novak, Akshay Sudhindra, Stephen M. Ansell, Thomas M. Habermann, Grzegorz S. Nowakowski, James R. Cerhan, Anne J. Novak, Anita K. Gandhi
Journal: Blood
Blood (2022) 140 (Supplement 1): 3548–3550.
https://doi.org/10.1182/blood-2022-170228
Published: 2022
Journal Articles

Loss of COP9 signalosome genes at 2q37 is associated with IMiD resistance in multiple myeloma

Brief Report
Sarah Gooding, Naser Ansari-Pour, Mohammad Kazeroun, Kubra Karagoz, Ann Polonskaia, Mirian Salazar, Evie Fitzsimons, Korsuk Sirinukunwattana, Selina Chavda, Maria Ortiz Estevez, Fadi Towfic, Erin Flynt, William Pierceall, Daniel Royston, Kwee Yong, Karthik Ramasamy, Paresh Vyas, Anjan Thakurta
Journal: Blood
Blood (2022) 140 (16): 1816–1821.
https://doi.org/10.1182/blood.2022015909
Published: 2022
Includes: Supplemental data
Journal Articles

Super-Enhancer Driven Regulation of CKS1B in Multiple Myeloma: Implications in Mediating Response to BET Inhibitor and Celmod Agent Combination

Aarif Ahsan, Ann Polonskaia, Chih-Chao Hsu, Chad C Bjorklund, Maria Ortiz Estevez, Fadi Towfic, Nizar J. Bahlis, Michael Pourdehnad, Erin Flynt, Aarif Ahsan, Anjan Thakurta
Journal: Blood
Blood (2021) 138 (Supplement 1): 2658.
https://doi.org/10.1182/blood-2021-150641
Published: 2021
Journal Articles

Loss of COP9 Signalosome Gene-Containing 2q Region Is Associated with Lenalidomide and Pomalidomide Resistance in Myeloma Patients

Sarah Gooding, Naser Ansari-Pour, Mohammad H Kazeroun, Kubra Karagoz, Mirian Angulo Salazar, Evelyn Fitzsimons, Maria Ortiz Estevez, Fadi Towfic, Erin Flynt, William E. Pierceall, Kwee Yong, Paresh Vyas, Anjan Thakurta
Journal: Blood
Blood (2021) 138 (Supplement 1): 458.
https://doi.org/10.1182/blood-2021-150166
Published: 2021
Journal Articles

Multiple cereblon genetic changes are associated with acquired resistance to lenalidomide or pomalidomide in multiple myeloma

Clinical Trials & Observations Brief Report
Sarah Gooding, Naser Ansari-Pour, Fadi Towfic, María Ortiz Estévez, Philip P. Chamberlain, Kao-Tai Tsai, Erin Flynt, Marissa Hirst, Dan Rozelle, Paula Dhiman, Paola Neri, Karthik Ramasamy, Nizar Bahlis, Paresh Vyas, Anjan Thakurta
Journal: Blood
Blood (2021) 137 (2): 232–237.
https://doi.org/10.1182/blood.2020007081
Published: 2021
Includes: Supplemental data
Journal Articles

Lenalidomide Exhibits Activity in Mantle Cell Lymphoma through Increased NK Cell Mediated Cytotoxicity

Patrick Hagner, PhD, Hsiling Chiu, Maria Ortiz-Estevez, Tsvetan Biyukov, Carrie Brachman, Marek Trneny, Luca Arcaini, Franck Morschhauser, MD, Antoine Thyss, Stephan Stilgenbauer, Noel Milpied, Reinhard Marks, Pellegrino Musto, Giovanni Martinelli, MD PhD, Carla Heise, Thomas Daniel, Rajesh Chopra, James Carmichael, Matthew Trotter, Anita K. Gandhi, PhD, Anjan Thakurta
Journal: Blood
Blood (2015) 126 (23): 821.
https://doi.org/10.1182/blood.V126.23.821.821
Published: 2015